{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T15:25:17Z","timestamp":1790522717768,"version":"4.1.0"},"update-to":[{"DOI":"10.1002\/14651858.cd007137.pub5","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2020,3,31]],"date-time":"2020-03-31T00:00:00Z","timestamp":1585612800000}}],"reference-count":72,"publisher":"Wiley","issue":"1","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd007137.pub6","type":"journal-article","created":{"date-parts":[[2020,3,31]],"date-time":"2020-03-31T12:23:32Z","timestamp":1585657412000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants"],"prefix":"10.1002","volume":"2021","author":[{"given":"Mohan","family":"Pammi","sequence":"additional","affiliation":[{"name":"Section of Neonatology, Department of Pediatrics; Baylor College of Medicine; Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanekal S","family":"Gautham","sequence":"additional","affiliation":[{"name":"Section of Neonatology, Department of Pediatrics; Baylor College of Medicine; Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,3,31]]},"reference":[{"issue":"12","key":"10.1002\/14651858.CD007137.pub6-BIB0001|cit1","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1055\/s-0034-1371704","article-title":"Oral lactoferrin to prevent nosocomial sepsis and necrotizing enterocolitis of premature neonates and effect on T-regulatory cells","volume":"31","author":"Akin","year":"2014","journal-title":"American Journal of Perinatology"},{"issue":"8","key":"10.1002\/14651858.CD007137.pub6-BIB0002|cit2","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1038\/jp.2016.24","article-title":"The Lacuna Trial: a double-blind randomized controlled pilot trial of lactoferrin supplementation in the very preterm infant","volume":"36","author":"Barrington","year":"2016","journal-title":"Journal of Perinatology"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0003|cit3","first-page":"98","article-title":"The effect of lactoferrin supplementation combining Lactobacillus rhamnosus for prevention of late onset sepsis in premature neonates","volume":"10","author":"Dai","year":"2015","journal-title":"China Practical Medicine"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0004|cit4","unstructured":"Enteral lactoferrin supplementation for very preterm infants: a randomised controlled trial isrctn.com\/ISRCTN88261002 10.1186\/ISRCTN88261002"},{"issue":"5","key":"10.1002\/14651858.CD007137.pub6-BIB0005|cit5","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1093\/tropej\/fmv044","article-title":"Efficacy of bovine lactoferrin supplementation in preventing late-onset sepsis in low birth weight neonates: a randomized placebo-controlled clinical trial","volume":"61","author":"Kaur","year":"2015","journal-title":"Journal of Tropical Pediatrics"},{"issue":"6","key":"10.1002\/14651858.CD007137.pub6-BIB0006|cit6","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1016\/S2352-4642(20)30093-6","article-title":"The Lactoferrin Infant Feeding Trial (LIFT): a pragmatic, randomised, multicentre study in very low birth weight infants","volume":"4","author":"Tarnow-Mordi","year":"2020","journal-title":"Lancet. Child and Adolescent Health."},{"issue":"21","key":"10.1002\/14651858.CD007137.pub6-BIB0007|cit7","first-page":"4464","article-title":"The effect of lactoferrin on low birth weight neonates during hospitalization","volume":"31","author":"Liu","year":"2016","journal-title":"Maternal and Child Health Care of China"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0008|cit8","doi-asserted-by":"publisher","first-page":"S60","DOI":"10.1016\/S0378-3782(14)70020-9","article-title":"Bovine lactoferrin supplementation for prevention of necrotizing enterocolitis in very-low-birth-weight neonates: a randomized clinical trial","volume":"90 Suppl 1","author":"Manzoni","year":"2014","journal-title":"Early Human Development"},{"issue":"13","key":"10.1002\/14651858.CD007137.pub6-BIB0009|cit9","doi-asserted-by":"publisher","first-page":"1421","DOI":"10.1001\/jama.2009.1403","article-title":"Bovine lactoferrin supplementation for prevention of late-onset sepsis in very low-birth-weight neonates: a randomized trial","volume":"302","author":"Manzoni","year":"2009","journal-title":"JAMA"},{"issue":"1","key":"10.1002\/14651858.CD007137.pub6-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1542\/peds.2011-0279","article-title":"Bovine lactoferrin prevents invasive fungal infections in very low birth weight infants: a randomized controlled trial","volume":"129","author":"Manzoni","year":"2012","journal-title":"Pediatrics"},{"issue":"6","key":"10.1002\/14651858.CD007137.pub6-BIB0011|cit11","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1097\/INF.0000000000000593","article-title":"Randomized controlled trial of lactoferrin for prevention of sepsis in Peruvian neonates less than 2500 g","volume":"34","author":"Ochoa","year":"2015","journal-title":"Pediatric Infectious Disease Journal"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0012|cit12","unstructured":"Ochoa T Zegarra J Bellomo S Carcamo C Cam L Castaneda A Neolacto Research Group Randomized controlled trial of bovine lactoferrin for prevention of sepsis and neurodevelopmental impairment in infants weighing less than 2000 grams Journal of Pediatrics"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0013|cit13","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.jpeds.2016.04.084","article-title":"Randomized controlled trial of talactoferrin oral solution in preterm infants","volume":"175","author":"Sherman","year":"2016","journal-title":"Journal of Pediatrics"},{"issue":"6","key":"10.1002\/14651858.CD007137.pub6-BIB0014|cit14","first-page":"1223","article-title":"Randomized control trial of lactoferrin for the prevention of late onset sepsis in premature neonates","volume":"32","author":"Tang","year":"2017","journal-title":"Maternal and Child Health Care of China"},{"issue":"2","key":"10.1002\/14651858.CD007137.pub6-BIB0015|cit15","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1097\/01.mpg.0000243435.54958.68","article-title":"A double-blind, placebo-controlled, pilot study of bovine lactoferrin supplementation in bottle-fed infants","volume":"44","author":"Cummings","year":"2007","journal-title":"Journal of Pediatric Gastroenterology and Nutrition"},{"issue":"3","key":"10.1002\/14651858.CD007137.pub6-BIB0016|cit16","doi-asserted-by":"publisher","first-page":"249","DOI":"10.3233\/NPM-16130","article-title":"Reduction in necrotizing enterocolitis and improved outcomes in preterm infants following routine supplementation with lactobacillus GG in combination with bovine lactoferrin","volume":"10","author":"Meyer","year":"2016","journal-title":"Journal of Neonatal-Perinatal Medicine"},{"issue":"2","key":"10.1002\/14651858.CD007137.pub6-BIB0017|cit17","doi-asserted-by":"publisher","first-page":"349\u201356","DOI":"10.1016\/j.jpeds.2012.07.043","article-title":"Randomized double-blind controlled trial of bovine lactoferrin for prevention of diarrhea in children","volume":"162","author":"Ochoa","year":"2013","journal-title":"Journal of Pediatrics"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0018|cit18","unstructured":"Effect of prebiotic or lactoferrin supplementation in formula on the gut flora of preterm infants isrctn.com\/ISRCTN71737811"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0019|cit19","unstructured":"Supplementation with lactoferrin in preterm newborns (lactoprenew) clinicaltrials.gov\/show\/NCT01172236"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0020|cit20","unstructured":"Early versus late lactoferrin in prevention of neonatal sepsis clinicaltrials.gov\/show\/NCT02959229"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0021|cit21","unstructured":"Oral lactoferrin supplementation for prevention of sepsis in preterm neonate clinicaltrials.gov\/show\/NCT01821989"},{"issue":"3","key":"10.1002\/14651858.CD007137.pub6-BIB0022|cit22","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1097\/01.qco.0000224825.57976.87","article-title":"Neonatal infection and long-term neurodevelopmental outcome in the preterm infant","volume":"19","author":"Adams-Chapman","year":"2006","journal-title":"Current Opinion in Infectious Diseases"},{"issue":"4","key":"10.1002\/14651858.CD007137.pub6-BIB0023|cit23","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005496.pub4","article-title":"Probiotics for prevention of necrotizing enterocolitis in preterm infants","author":"AlFaleh","year":"2014","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"6","key":"10.1002\/14651858.CD007137.pub6-BIB0024|cit24","doi-asserted-by":"publisher","first-page":"M111.015248","DOI":"10.1074\/mcp.M111.015248","article-title":"Glycosylation of human milk lactoferrin exhibits dynamic changes during early lactation enhancing its role in pathogenic bacteria-host interactions","volume":"11","author":"Barboza","year":"2012","journal-title":"Molecular Cell Proteomics"},{"issue":"1","key":"10.1002\/14651858.CD007137.pub6-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00000658-197801000-00001","article-title":"Neonatal necrotizing enterocolitis. Therapeutic decisions based upon clinical staging","volume":"187","author":"Bell","year":"1978","journal-title":"Annals of Surgery"},{"issue":"6","key":"10.1002\/14651858.CD007137.pub6-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1111\/j.1365-2672.1992.tb05007.x","article-title":"Antibacterial spectrum of lactoferricin B, a potent bactericidal peptide derived from the N-terminal region of bovine lactoferrin","volume":"73","author":"Bellamy","year":"1992","journal-title":"Journal of Applied Bacteriology"},{"issue":"1","key":"10.1002\/14651858.CD007137.pub6-BIB0027|cit27","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1165\/ajrcmb.17.1.f132","article-title":"The role of nuclear factor-kappa B in cytokine gene regulation","volume":"17","author":"Blackwell","year":"1997","journal-title":"American Journal of Respiratory Cell and Molecular Biology"},{"issue":"4","key":"10.1002\/14651858.CD007137.pub6-BIB0028|cit28","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1203\/pdr.0b013e3180332c8d","article-title":"Lactoferrin induces concentration-dependent functional modulation of intestinal proliferation and differentiation","volume":"61","author":"Buccigrossi","year":"2007","journal-title":"Pediatric Research"},{"issue":"2","key":"10.1002\/14651858.CD007137.pub6-BIB0029|cit29","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1007\/s10534-017-9999-8","article-title":"Prebiotic effects of bovine lactoferrin on specific probiotic bacteria","volume":"30","author":"Chen","year":"2017","journal-title":"Biometals"},{"issue":"1","key":"10.1002\/14651858.CD007137.pub6-BIB0030|cit30","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1159\/000454668","article-title":"The \"golden age\" of probiotics: a systematic review and meta-analysis of randomized and observational studies in preterm infants","volume":"112","author":"Dermyshi","year":"2017","journal-title":"Neonatology"},{"issue":"5","key":"10.1002\/14651858.CD007137.pub6-BIB0031|cit31","doi-asserted-by":"publisher","first-page":"G1140","DOI":"10.1152\/ajpgi.2001.281.5.G1140","article-title":"Lactoferrin protects neonatal rats from gut-related systemic infection","volume":"281","author":"Edde","year":"2001","journal-title":"American Journal of Physiology. Gastrointestinal and Liver Physiology"},{"issue":"22","key":"10.1002\/14651858.CD007137.pub6-BIB0032|cit32","doi-asserted-by":"publisher","first-page":"2588","DOI":"10.1007\/s00018-005-5373-z","article-title":"Lactoferricin: a lactoferrin-derived peptide with antimicrobial, antiviral, antitumor and immunological properties","volume":"62","author":"Gifford","year":"2005","journal-title":"Cellular and Molecular Life Sciences"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0033|cit33","unstructured":"GRADEpro GDT McMaster University (developed by Evidence Prime) 2015"},{"issue":"7650","key":"10.1002\/14651858.CD007137.pub6-BIB0034|cit34","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"issue":"3","key":"10.1002\/14651858.CD007137.pub6-BIB0035|cit35","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1007\/s10637-005-3690-6","article-title":"Phase I trial of oral talactoferrin alfa in refractory solid tumors","volume":"24","author":"Hayes","year":"2006","journal-title":"Investigational New Drugs"},{"issue":"35","key":"10.1002\/14651858.CD007137.pub6-BIB0036|cit36","doi-asserted-by":"publisher","first-page":"e11976","DOI":"10.1097\/MD.0000000000011976","article-title":"Prophylactic lactoferrin for preventing late-onset sepsis and necrotizing enterocolitis in preterm infants","volume":"97","author":"He","year":"2018","journal-title":"Medicine"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0037|cit37","unstructured":"Higgins JP Green S Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from handbook.cochrane.org"},{"issue":"3","key":"10.1002\/14651858.CD007137.pub6-BIB0038|cit38","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1111\/j.1572-0241.2002.05573.x","article-title":"Lactoferrin inhibits hepatitis C virus viremia in chronic hepatitis C patients with high viral loads and HCV genotype 1b","volume":"97","author":"Iwasa","year":"2002","journal-title":"American Journal of Gastroenterology"},{"issue":"11","key":"10.1002\/14651858.CD007137.pub6-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1128\/AAC.43.11.2635","article-title":"Synergistic fungistatic effects of lactoferrin in combination with antifungal drugs against clinical Candida isolates","volume":"43","author":"Kuipers","year":"1999","journal-title":"Antimicrobial Agents and Chemotherapy"},{"issue":"3","key":"10.1002\/14651858.CD007137.pub6-BIB0040|cit40","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1093\/ije\/dyl043","article-title":"Estimating the causes of 4 million neonatal deaths in the year 2000","volume":"35","author":"Lawn","year":"2006","journal-title":"International Journal of Epidemiology"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0041|cit41","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1128\/IAI.66.4.1421-1426.1998","article-title":"The protective effects of lactoferrin feeding against endotoxin lethal shock in germfree piglets","volume":"66","author":"Lee","year":"1998","journal-title":"Infect Immun"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0042|cit42","doi-asserted-by":"publisher","first-page":"S10","DOI":"10.1016\/j.jpeds.2016.02.071","article-title":"Overview of lactoferrin as a natural immune modulator","volume":"173 Suppl","author":"Legrand","year":"2016","journal-title":"Journal of Pediatrics"},{"issue":"1","key":"10.1002\/14651858.CD007137.pub6-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1076\/ceyr.19.1.12.5342","article-title":"Lactoferrin increases the susceptibility of S. epidermidis biofilms to lysozyme and vancomycin","volume":"19","author":"Leitch","year":"1999","journal-title":"Current Eye Research"},{"issue":"7159","key":"10.1002\/14651858.CD007137.pub6-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1136\/bmj.317.7159.612","article-title":"Antimicrobial resistance: bacteria on the defence. Resistance stems from misguided efforts to try to sterilize our environment","volume":"317","author":"Levy","year":"1998","journal-title":"BMJ"},{"issue":"9543","key":"10.1002\/14651858.CD007137.pub6-BIB0045|cit45","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1016\/S0140-6736(06)69525-1","article-title":"Necrotizing enterocolitis","volume":"368","author":"Lin","year":"2006","journal-title":"Lancet"},{"issue":"7","key":"10.1002\/14651858.CD007137.pub6-BIB0046|cit46","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1586\/14787210.2013.811927","article-title":"Lactoferrin and the newborn: current perspectives","volume":"11","author":"Lingappan","year":"2013","journal-title":"Expert Reviews of Anti-Infective Therapy"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0047|cit47","doi-asserted-by":"crossref","first-page":"S43","DOI":"10.1016\/j.jpeds.2016.02.075","article-title":"Clinical benefits of lactoferrin for infants and children","volume":"173 Suppl","author":"Manzoni","year":"2016","journal-title":"Journal of Pediatrics"},{"issue":"2","key":"10.1002\/14651858.CD007137.pub6-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/00054725-200403000-00015","article-title":"Molecular aspects of intestinal epithelial cell-bacterial interactions that determine the development of intestinal inflammation","volume":"10","author":"Neish","year":"2004","journal-title":"Inflammatory Bowel Diseases"},{"issue":"3","key":"10.1002\/14651858.CD007137.pub6-BIB0049|cit49","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.1128\/IAI.69.3.1469-1476.2001","article-title":"Human lactoferrin and peptides derived from its N terminus are highly effective against infections with antibiotic-resistant bacteria","volume":"69","author":"Nibbering","year":"2001","journal-title":"Infection and Immunity"},{"issue":"1","key":"10.1002\/14651858.CD007137.pub6-BIB0050|cit50","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1139\/bcb-2016-0066","article-title":"Lactoferrin and prematurity: a promising milk protein?","volume":"95","author":"Ochoa","year":"2017","journal-title":"Biochemistry and Cell Biology"},{"issue":"1","key":"10.1002\/14651858.CD007137.pub6-BIB0051|cit51","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/j.1432-1033.1991.tb15801.x","article-title":"Molecular cloning and sequence analysis of bovine lactotransferrin","volume":"196","author":"Pierce","year":"1991","journal-title":"European Journal of Biochemistry"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0052|cit52","unstructured":"Review Manager 5 (RevMan 5) Nordic Cochrane Centre, The Cochrane Collaboration 2014"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0053|cit53","unstructured":"Sch\u00fcnemann H Bro\u017cek J Guyatt G Oxman A GRADE Working Group Handbook for grading the quality of evidence and the strength of recommendations using the GRADE approach (updated October 2013) gdt.gradepro.org\/app\/handbook\/handbook.html"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0054|cit54","doi-asserted-by":"crossref","first-page":"S18","DOI":"10.1007\/PL00014314","article-title":"Inflammatory mechanisms in neonatal chronic lung disease","volume":"158 Suppl 1","author":"Speer","year":"1999","journal-title":"European Journal of Pediatrics"},{"issue":"2 Pt 1","key":"10.1002\/14651858.CD007137.pub6-BIB0055|cit55","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1542\/peds.110.2.285","article-title":"Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network","volume":"110","author":"Stoll","year":"2002","journal-title":"Pediatrics"},{"issue":"19","key":"10.1002\/14651858.CD007137.pub6-BIB0056|cit56","doi-asserted-by":"publisher","first-page":"2357","DOI":"10.1001\/jama.292.19.2357","article-title":"Neurodevelopmental and growth impairment among extremely low-birth-weight infants with neonatal infection","volume":"292","author":"Stoll","year":"2004","journal-title":"JAMA"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0057|cit57","first-page":"623","volume-title":"Nelson's Textbook of Pediatrics","author":"Stoll","year":"2004"},{"issue":"7","key":"10.1002\/14651858.CD007137.pub6-BIB0058|cit58","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1097\/01.inf.0000168749.82105.64","article-title":"Very low birth weight preterm infants with early onset neonatal sepsis: the predominance of gram-negative infections continues in the National Institute of Child Health and Human Development Neonatal Research Network, 2002-2003","volume":"24","author":"Stoll","year":"2005","journal-title":"Pediatric Infectious Disease Journal"},{"issue":"4","key":"10.1002\/14651858.CD007137.pub6-BIB0059|cit59","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1111\/j.1349-7006.1999.tb00756.x","article-title":"Lactoferrin inhibits hepatitis C virus viremia in patients with chronic hepatitis C: a pilot study","volume":"90","author":"Tanaka","year":"1999","journal-title":"Japanese Journal of Cancer Research"},{"issue":"3","key":"10.1002\/14651858.CD007137.pub6-BIB0060|cit60","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1007\/s10534-010-9318-0","article-title":"Influence of bovine lactoferrin on selected probiotic bacteria and intestinal pathogens","volume":"23","author":"Tian","year":"2010","journal-title":"Biometals"},{"issue":"1","key":"10.1002\/14651858.CD007137.pub6-BIB0061|cit61","doi-asserted-by":"publisher","first-page":"G187","DOI":"10.1152\/ajpgi.00331.2001","article-title":"Lactoferrin reduces colitis in rats via modulation of the immune system and correction of cytokine imbalance","volume":"283","author":"Togawa","year":"2002","journal-title":"American Journal of Physiology. Gastrointestinal and Liver Physiology"},{"issue":"1","key":"10.1002\/14651858.CD007137.pub6-BIB0062|cit62","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1139\/o01-230","article-title":"Bovine lactoferrin and lactoferricin derived from milk: production and applications","volume":"80","author":"Tomita","year":"2002","journal-title":"Biochemistry and Cell Biology"},{"issue":"4","key":"10.1002\/14651858.CD007137.pub6-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1007\/BF01963459","article-title":"Antibacterial prophylaxis with lactoferrin in neutropenic patients","volume":"8","author":"Trumpler","year":"1989","journal-title":"European Journal of Clinical Microbiology and Infectious Diseases"},{"issue":"5","key":"10.1002\/14651858.CD007137.pub6-BIB0064|cit64","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1007\/s10534-014-9754-3","article-title":"Lactoferrin for prevention of neonatal sepsis","volume":"27","author":"Turin","year":"2014","journal-title":"Biometals"},{"issue":"22","key":"10.1002\/14651858.CD007137.pub6-BIB0065|cit65","doi-asserted-by":"publisher","first-page":"2576","DOI":"10.1007\/s00018-005-5372-0","article-title":"Lactoferrin: an important host defence against microbial and viral attack","volume":"62","author":"Valenti","year":"2005","journal-title":"Cellular and Molecular Life Sciences"},{"issue":"5","key":"10.1002\/14651858.CD007137.pub6-BIB0066|cit66","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1007\/BF02877698","article-title":"Prophylaxis with lactoferrin, a novel antimicrobial agent, enhances survival in a neonatal rat model of co-infection","volume":"24","author":"Venkatesh","year":"2007","journal-title":"Advances in Therapy"},{"key":"10.1002\/14651858.CD007137.pub6-BIB0067|cit67","volume-title":"Neurology of the Newborn","author":"Volpe","year":"1995"},{"issue":"6","key":"10.1002\/14651858.CD007137.pub6-BIB0068|cit68","first-page":"697","article-title":"Lactoferrin can protect mice against a lethal dose of Escherichia coli in experimental infection in vivo","volume":"70","author":"Zagulski","year":"1989","journal-title":"British Journal of Experimental Pathology"},{"issue":"9465","key":"10.1002\/14651858.CD007137.pub6-BIB0069|cit69","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1016\/S0140-6736(05)71881-X","article-title":"Hospital-acquired neonatal infections in developing countries","volume":"365","author":"Zaidi","year":"2005","journal-title":"Lancet"},{"issue":"5","key":"10.1002\/14651858.CD007137.pub6-BIB0070|cit70","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007137.pub2","article-title":"Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants","author":"Pammi","year":"2010","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"10","key":"10.1002\/14651858.CD007137.pub6-BIB0071|cit71","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007137.pub3","article-title":"Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants","author":"Pammi","year":"2011","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"2","key":"10.1002\/14651858.CD007137.pub6-BIB0072|cit72","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007137.pub4","article-title":"Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants","author":"Pammi","year":"2015","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","deposited":{"date-parts":[[2025,3,20]],"date-time":"2025-03-20T03:17:07Z","timestamp":1742440627000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD007137.pub6"}},"subtitle":[],"editor":[{"name":"Cochrane Neonatal Group","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,3,31]]},"references-count":72,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,1]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd007137.pub6","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,31]]}}}