{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T20:34:47Z","timestamp":1780432487920,"version":"3.54.1"},"update-to":[{"DOI":"10.1002\/14651858.cd007388.pub2","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:00:00Z","timestamp":1696896000000}}],"reference-count":168,"publisher":"Wiley","issue":"10","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd007388.pub3","type":"journal-article","created":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T23:38:07Z","timestamp":1697067487000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Alternative magnesium sulphate regimens for women with pre-eclampsia and eclampsia"],"prefix":"10.1002","volume":"2023","author":[{"given":"Virginia","family":"Diaz","sequence":"additional","affiliation":[{"name":"Centro Rosarino de Estudios Perinatales (CREP); Rosario Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Long","sequence":"additional","affiliation":[{"name":"Global Health Research Center; Duke Kunshan University; Kunshan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olufemi T","family":"Oladapo","sequence":"additional","affiliation":[{"name":"UNDP\/UNFPA\/UNICEF\/WHO\/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Sexual and Reproductive Health and Research; World Health Organization; Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,10]]},"reference":[{"issue":"1","key":"10.1002\/14651858.CD007388.pub3-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"82","DOI":"10.3109\/10641950902928704","article-title":"Zuspan's scheme versus an alternative magnesium sulfate scheme: Randomized clinical trial of magnesium serum concentrations","volume":"29","author":"Abbade","year":"2010","journal-title":"Hypertension in Pregnancy"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD007388.pub3-BIB0002|cit2","first-page":"152","article-title":"Zuspan's scheme versus alternative scheme of magnesium sulphate to prevent or to treat eclampsia: comparison of magnesium serum concentrations [abstract]","volume":"25","author":"Abbade","year":"2006","journal-title":"Hypertension in Pregnancy"},{"issue":"4","key":"10.1002\/14651858.CD007388.pub3-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"298","DOI":"10.3109\/01443615.2010.549972","article-title":"A randomised comparative study between low-dose intravenous magnesium sulphate and standard intramuscular regimen for treatment of eclampsia","volume":"31","author":"Bhattacharjee","year":"2011","journal-title":"Journal of Obstetrics and Gynaecology"},{"issue":"1","key":"10.1002\/14651858.CD007388.pub3-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1016\/j.ajog.2019.11.035","article-title":"19: a randomized trial of an alternate dosing protocol of magnesium sulfate in obese preeclamptic women","volume":"222","author":"Brookfield","year":"2020","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"6","key":"10.1002\/14651858.CD007388.pub3-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1097\/AOG.0000000000004137","article-title":"Alternate dosing protocol for magnesium sulfate in obese women with preeclampsia: a randomized controlled trial","volume":"136","author":"Brookfield","year":"2020","journal-title":"Obstetrics and Gynecology"},{"issue":"1","key":"10.1002\/14651858.CD007388.pub3-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"S500","DOI":"10.1016\/j.ajog.2019.11.805","article-title":"789: do alternative magnesium sulfate protocols in obese preeclamptic women impact neonatal morbidity?","volume":"222","author":"Vinson","year":"2020","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0007|cit7","first-page":"607","article-title":"Intravenous and intramuscular magnesium sulphate regimens in severe pre-eclampsia","volume":"84","author":"Chissell","year":"1994","journal-title":"South African Medical Journal"},{"issue":"1","key":"10.1002\/14651858.CD007388.pub3-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1186\/s12884-018-1919-6","article-title":"A randomized trial comparing the pharmacology of magnesium sulfate when used to treat severe preeclampsia with serial intravenous boluses versus a continuous intravenous infusion","volume":"18","author":"Easterling","year":"2018","journal-title":"BMC Pregnancy and Childbirth"},{"issue":"6 Suppl 1","key":"10.1002\/14651858.CD007388.pub3-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"S73","DOI":"10.1016\/j.ajog.2004.10.136","article-title":"Abbreviated post-partum magnesium sulfate therapy for women with mild preeclampsia [abstract]","volume":"191","author":"Ehrenberg","year":"2004","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"4","key":"10.1002\/14651858.CD007388.pub3-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1097\/01.AOG.0000236493.35347.d8","article-title":"Abbreviated postpartum magnesium sulfate therapy for women with mild preeclampsia: a randomized controlled trial","volume":"108","author":"Ehrenberg","year":"2006","journal-title":"Obstetrics & Gynecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0011|cit11","unstructured":"Abbreviated post-partum magnesium sulfate seizure prophylaxis in preeclampsia: a comparison of 12 and 24 hour regimens clinicaltrials.gov\/ct2\/show\/record\/NCT00344058"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.preghy.2016.08.017","article-title":"Serum magnesemia during maintenance dose of 1 g\/h vs. 2 g\/h of magnesium sulfate infusion for the prevention of eclampsia in women with severe preeclampsia: Randomized trial","volume":"6","author":"Katz","year":"2016","journal-title":"Pregnancy Hypertension"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0013|cit13","unstructured":"Effectiveness and safety of 1g\/hour vs. 2g\/hour of magnesium sulfate maintenance dose for eclampsia prevention: randomized clinical trial https:\/\/clinicaltrials.gov\/show\/NCT02396030"},{"issue":"32","key":"10.1002\/14651858.CD007388.pub3-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"e16779","DOI":"10.1097\/MD.0000000000016779","article-title":"Serum magnesium levels during magnesium sulfate infusion at 1 gram\/hour versus 2 grams\/hour as a maintenance dose to prevent eclampsia in women with severe preeclampsia: a randomized clinical trial","volume":"98","author":"Pascoal","year":"2019","journal-title":"Medicine"},{"issue":"3","key":"10.1002\/14651858.CD007388.pub3-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1080\/01443615.2017.1351931","article-title":"Prophylactic magnesium sulphate in prevention of eclampsia in women with severe preeclampsia: randomised controlled trial (PIPES trial)","volume":"38","author":"Keepanasseril","year":"2018","journal-title":"Journal of Obstetrics and Gynaecology"},{"issue":"5 Suppl","key":"10.1002\/14651858.CD007388.pub3-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"64S","DOI":"10.1097\/01.AOG.0000447370.59285.a5","article-title":"12-hour compared with 24-hour postpartum magnesium sulfate therapy in preeclampsia: a randomized clinical trial","volume":"123","author":"Leal","year":"2014","journal-title":"Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.ijgo.2014.03.024","article-title":"Abbreviated (12-hour) versus traditional (24-hour) postpartum magnesium sulfate therapy in severe pre-eclampsia","volume":"126","author":"Maia","year":"2014","journal-title":"International Journal of Gynecology & Obstetrics"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0018|cit18","unstructured":"Postpartum prophylaxis with short course magnesium sulfate in severe preeclampsia: a randomized clinical trial https:\/\/clinicaltrials.gov\/ct2\/show\/record\/NCT01408979"},{"issue":"1","key":"10.1002\/14651858.CD007388.pub3-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s00404-012-2523-z","article-title":"Low-dose magnesium sulphate in the control of eclamptic fits: A randomized controlled trial","volume":"287","author":"Abdul","year":"2013","journal-title":"Archives of Gynecology and Obstetrics"},{"issue":"Suppl 2","key":"10.1002\/14651858.CD007388.pub3-BIB0020|cit20","first-page":"S277","article-title":"Low dose magnesium sulfate in the control of eclamptic fits: a randomized control trial","volume":"107","author":"Muhammad","year":"2009","journal-title":"International Journal of Gynecology & Obstetrics"},{"issue":"8","key":"10.1002\/14651858.CD007388.pub3-BIB0021|cit21","first-page":"7","article-title":"Comparison of efficacy and safety of magnesium sulphate in 12 hours versus 24 hours after last fit in eclamptic patients","volume":"26","author":"Rao","year":"2015","journal-title":"Medical Forum Monthly"},{"issue":"4","key":"10.1002\/14651858.CD007388.pub3-BIB0022|cit22","first-page":"244","article-title":"Loading dose versus standard regimen of magnesium sulphate in eclampsia \u2013 a randomized trial","volume":"12","author":"Regmi","year":"2010","journal-title":"Nepal Medical College Journal: NMCJ"},{"issue":"208","key":"10.1002\/14651858.CD007388.pub3-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"388","DOI":"10.31729\/jnma.3431","article-title":"Loading dose only versus standard dose magnesium sulfate seizure prophylaxis in severe pre-eclamptic women","volume":"56","author":"Rimal","year":"2017","journal-title":"Journal of the Nepal Medical Association"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0024|cit24","first-page":"55","article-title":"A randomized controlled trial of loading dose only versus standard dose magnesium sulfate seizure prophylaxis in severe pre-eclamptic women","volume":"29(Suppl 1)","author":"Rimal","year":"2016","journal-title":"Journal of Maternal-Fetal and Neonatal Medicine"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0025|cit25","unstructured":"Comparison of magnesium sulphate protocol by weight-adjusted versus 2 grams per hour for preventing convulsion in preeclampsia: a randomized trial www.who.int\/trialsearch\/Trial2.aspx?TrialID=TCTR20180122001"},{"issue":"2","key":"10.1002\/14651858.CD007388.pub3-BIB0026|cit26","first-page":"QC01","article-title":"Comparison of magnesium sulphate protocols by weight-adjusted versus two grams per hour for preventing convulsion in preeclampsia: a randomised controlled trial","volume":"13","author":"Tungmanowutthikul","year":"2019","journal-title":"Journal of Clinical and Diagnostic Research"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0027|cit27","unstructured":"A novel protocol for postpartum magnesium sulfate in severe preeclampsia when the woman received less that 8 hours before delivery. Six versus twenty-four hours postpartum clinicaltrials.gov\/ct2\/show\/record\/NCT02317146"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0028|cit28","doi-asserted-by":"crossref","unstructured":"Vigil-De Gracia P Ramirez R Duran Y Quintero A Magnesium sulfate for 6 vs 24 hours post delivery in patients who received magnesium sulfate for less than 8 hours before birth: a randomized clinical trial BMC Pregnancy and Childbirth 2017 17 1 241","DOI":"10.1186\/s12884-017-1424-3"},{"issue":"1","key":"10.1002\/14651858.CD007388.pub3-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.ajog.2016.11.005","article-title":"Is magnesium sulfate use of benefit post partum? A randomized controlled trial","volume":"216","author":"Ludmir","year":"2017","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0030|cit30","unstructured":"Magnesium sulfate during the postpartum in women with severe preeclampsia clinicaltrials.gov\/show\/NCT02307201"},{"issue":"10","key":"10.1002\/14651858.CD007388.pub3-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1111\/1471-0528.15317","article-title":"Safety of eliminating postpartum magnesium sulfate: intriguing but not yet proven","volume":"125","author":"Scott","year":"2018","journal-title":"BJOG: an International Journal of Obstetrics and Gynaecology"},{"issue":"10","key":"10.1002\/14651858.CD007388.pub3-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1111\/1471-0528.15320","article-title":"Is there benefit to continue magnesium sulfate post-partum in women receiving magnesium sulfate prior to delivery? A randomized controlled study","volume":"125","author":"Vigil-De Gracia","year":"2018","journal-title":"BJOG: an International Journal of Obstetrics and Gynaecology"},{"issue":"5","key":"10.1002\/14651858.CD007388.pub3-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1007\/s00404-015-3903-y","article-title":"Short-course postpartum (6-h) magnesium sulfate therapy in severe preeclampsia","volume":"293","author":"Anjum","year":"2016","journal-title":"Archives of Gynecology and Obstetrics"},{"issue":"1","key":"10.1002\/14651858.CD007388.pub3-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.ijgo.2015.06.056","article-title":"Maternal outcomes after 12 hours and 24 hours of magnesium sulfate therapy for eclampsia","volume":"132","author":"Anjum","year":"2016","journal-title":"International Journal of Gynecology & Obstetrics"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0035|cit35","unstructured":"Post partum seizure prophylaxis with short course magnesium sulfate therapy in severe preeclampsia ctri.nic.in\/Clinicaltrials\/pmaindet2.php?trialid=14387"},{"issue":"1","key":"10.1002\/14651858.CD007388.pub3-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1447-0756.2008.00842.x","article-title":"Comparison of intramuscular magnesium sulfate with low dose intravenous magnesium sulfate regimen for treatment of eclampsia","volume":"35","author":"Chowdhury","year":"2009","journal-title":"Journal of Obstetrics and Gynaecology Research"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0037|cit37","unstructured":"Dewan M Munshi S Different anticonvulsant regimen of magnesium sulphate and feto-maternal outcome in treatment of eclampsia 54th All India Congress of Obstetrics and Gynaecology; 2011 Jan 5-9; Hyderabad, Andhra Pradesh, India 2011 55"},{"issue":"1","key":"10.1002\/14651858.CD007388.pub3-BIB0038|cit38","first-page":"6","article-title":"A comparison between intravenous magnesium sulfate and oral magnesium chloride in mild preeclampsia","volume":"10","author":"Ghahiri","year":"2005","journal-title":"Journal of Research in Medical Sciences"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0039|cit39","unstructured":"Gloeb DJ O'Sullivan MJ Comparison of effects of intramuscular and intravenous magnesium sulfate regimens in pre-eclamptic patients on intrapartum events and maternal\/neonatal outcome 9th Annual Meeting of the Society of Perinatal Obstetricians; 1989 Feb 1-4; New Orleans, Louisiana, USA 1989 494"},{"issue":"1","key":"10.1002\/14651858.CD007388.pub3-BIB0040|cit40","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.ijgo.2011.05.013","article-title":"Low-dose magnesium sulfate versus Pritchard regimen for the treatment of eclampsia imminent eclampsia","volume":"115","author":"Malapaka","year":"2011","journal-title":"International Journal of Gynecology & Obstetrics"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0041|cit41","unstructured":"Sinha S Suneja A Vaid NB Ahuja S Is a 24 hour postpartum magnesium sulfate regime justified for all patients with severe preeclampsia? Personal communication 2010"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0042|cit42","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/0002-9378(81)90208-8","article-title":"The effect of magnesium sulfate on fetal heart rate variability and uterine activity","volume":"140","author":"Stallworth","year":"1981","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"Suppl 5","key":"10.1002\/14651858.CD007388.pub3-BIB0043|cit43","first-page":"E455","article-title":"Addition of lignocaine in intramuscular injection of magnesium sulphate: Does it reduce pain in women with severe preeclampsis and conscious eclamptic women? A randomized controlled trial","volume":"131","author":"Swathi","year":"2015","journal-title":"International Journal of Gynecology & Obstetrics"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0044|cit44","first-page":"150","article-title":"Modification of Pritchard regimen of magnesium sulphate for the conditions of a developing country","volume":"126","author":"Agarwal","year":"2019","journal-title":"BJOG: an International Journal of Obstetrics and Gynaecology"},{"issue":"Suppl 5","key":"10.1002\/14651858.CD007388.pub3-BIB0045|cit45","first-page":"E183","article-title":"Evaluation of medium dose versus standard Pritchard regime of magnesium sulfate in the management of eclampsia in developing nation","volume":"131","author":"Agrawal","year":"2015","journal-title":"International Journal of Gynecology and Obstetrics"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0046|cit46","doi-asserted-by":"crossref","unstructured":"Begum A Loading dose vs standard regime of magnesium sulphate in the management of eclampsia \u2013 a randomized trial [abstract] XVI FIGO World Congress of Obstetrics & Gynecology (Book 2); 2000 Sep 3-8; Washington, DC, USA 2000 47","DOI":"10.1016\/S0020-7292(00)86252-9"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0047|cit47","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1046\/j.1341-8076.2002.00029.x","article-title":"Loading dose versus standard regime of magnesium sulfate in the management of eclampsia: a randomized trial","volume":"28","author":"Begum","year":"2002","journal-title":"Journal of Obstetrics and Gynaecology Research"},{"issue":"Suppl 2","key":"10.1002\/14651858.CD007388.pub3-BIB0048|cit48","first-page":"S124","article-title":"A lower dose of magnesium sulphate for control of convulsion in eclamptic women of Bangladesh","volume":"107","author":"Begum","year":"2009","journal-title":"International Journal of Gynecology & Obstetrics"},{"issue":"2","key":"10.1002\/14651858.CD007388.pub3-BIB0049|cit49","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3329\/bjog.v25i2.13743","article-title":"A lower dose of magnesium sulphate for control of convulsion in eclamptic women of Bangladesh","volume":"25","author":"Sultana","year":"2010","journal-title":"Bangladesh Journal of Obstetrics and Gynecology"},{"issue":"10","key":"10.1002\/14651858.CD007388.pub3-BIB0050|cit50","doi-asserted-by":"crossref","first-page":"e032799","DOI":"10.1136\/bmjopen-2019-032799","article-title":"Open-labelled randomised controlled trial of 12 hours versus 24 hours modified Pritchard regimen in the management of eclampsia and pre-eclampsia in Ghana (MOPEP Study): study protocol","volume":"9","author":"Beyuo","year":"2019","journal-title":"BMJ Open"},{"issue":"2","key":"10.1002\/14651858.CD007388.pub3-BIB0051|cit51","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1002\/ijgo.14181","article-title":"A novel 12-hour versus 24-hour magnesium sulfate regimen in the management of eclampsia and preeclampsia in Ghana (MOPEP Study): a randomized controlled trial","volume":"159","author":"Beyuo","year":"2022","journal-title":"International Journal of Gynaecology and Obstetrics"},{"issue":"3","key":"10.1002\/14651858.CD007388.pub3-BIB0052|cit52","first-page":"131","article-title":"A shortened versus standard matched postpartum magnesium sulphate regimen in the treatment of eclampsia: a randomised controlled trial","volume":"17","author":"Chama","year":"2013","journal-title":"African Journal of Reproductive Health"},{"issue":"4","key":"10.1002\/14651858.CD007388.pub3-BIB0053|cit53","first-page":"395","article-title":"Magnesium sulfate maintenance infusion in women with preeclampsia: a randomized comparison between 2 gram per hour and 1 gram per hour","volume":"96","author":"Charoenvidhya","year":"2013","journal-title":"Journal of the Medical Association of Thailand"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0054|cit54","unstructured":"Magnesium sulfate maintenance infusion in woman with preeclampsia, compares between 2gm\/hr and 1 gm\/hr www.who.int\/trialsearch\/Trial2.aspx?TrialID=TCTR20120000009"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0055|cit55","unstructured":"Randomized controlled trial comparing two different regimes of magnesium sulphate in severe pre-eclampsia: a pilot study ctri.nic.in\/Clinicaltrials\/pmaindet2.php?trialid=4131"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0056|cit56","unstructured":"Is the Z track technique of intramuscular injection reduces the pain, drug leakage, post injection gluteal inflammation? www.who.int\/trialsearch\/Trial2.aspx?TrialID=CTRI\/2020\/05\/025165"},{"issue":"3","key":"10.1002\/14651858.CD007388.pub3-BIB0057|cit57","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.ijgo.2011.09.028","article-title":"A shortened postpartum magnesium sulfate prophylaxis regime in pre-eclamptic women at low risk of eclampsia","volume":"116","author":"Darngawn","year":"2012","journal-title":"International Journal of Gynecology & Obstetrics"},{"issue":"9","key":"10.1002\/14651858.CD007388.pub3-BIB0058|cit58","first-page":"1","article-title":"Abbreviated (8 hours) versus traditional (24 hours) postpartum mgso4 prophylaxis in severe preeclampsia: a randomised control trial","volume":"15","author":"Dasgupta","year":"2021","journal-title":"Journal of Clinical and Diagnostic Research"},{"issue":"1","key":"10.1002\/14651858.CD007388.pub3-BIB0059|cit59","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3109\/14767058.2014.991915","article-title":"A novel protocol for post partum magnesium sulphate in severe pre-eclampsia: a randomized controlled pilot trial","volume":"29","author":"El-Khayat","year":"2016","journal-title":"Journal of Maternal-Fetal & Neonatal Medicine"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0060|cit60","unstructured":"New magnesium sulphate protocol for pre-eclampsia clinicaltrials.gov\/show\/NCT01846156"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0061|cit61","unstructured":"Magnesium sulphate in continuous administration compare to discontinuous administration in the expectant management of severe preeclampsia: randomized controlled trial clinicaltrialsregister.eu\/ctr-search\/trial\/2011-002095-17\/ES\/"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0062|cit62","doi-asserted-by":"crossref","first-page":"e21","DOI":"10.1016\/j.preghy.2021.07.016","article-title":"Y-011. Comparison of zuspan regime and its 12-hour modification in women with severe pre-eclampsia and eclampsia in two hospitals in Abeokuta, South Western Nigeria","volume":"25","author":"Grillo","year":"2021","journal-title":"Pregnancy Hypertension"},{"issue":"2","key":"10.1002\/14651858.CD007388.pub3-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"85","DOI":"10.5005\/jp-journals-10006-1661","article-title":"Low-dose intravenous magnesium sulfate: efficacy and safety in eclamptic Indian women","volume":"11","author":"Gupta","year":"2019","journal-title":"Journal of SAFOG"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0064|cit64","unstructured":"A comparison between 2 methods of magnesium sulfate administration for 12 or 24 hours after delivery in patients with severe preeclampsia http:\/\/en.search.irct.ir\/view\/10284"},{"issue":"4","key":"10.1002\/14651858.CD007388.pub3-BIB0065|cit65","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.3109\/14767058.2015.1083547","article-title":"A comparison between the two methods of magnesium sulfate administration for duration of 12 versus 24 h after delivery in patients with severe preeclampsia","volume":"29","author":"Kashanian","year":"2016","journal-title":"Journal of Maternal-Fetal & Neonatal Medicine"},{"issue":"8","key":"10.1002\/14651858.CD007388.pub3-BIB0066|cit66","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.21608\/ejhm.2019.28864","article-title":"Management of women with severe preeclampsia by different regimens of magnesium sulfate","volume":"74","author":"Khalifa","year":"2019","journal-title":"Egyptian Journal of Hospital Medicine"},{"issue":"2","key":"10.1002\/14651858.CD007388.pub3-BIB0067|cit67","first-page":"365","article-title":"Comparison of 12 hours versus 24 hours intravenous administration of MgSO4 in the management of eclampsia","volume":"15","author":"Khan","year":"2021","journal-title":"Pakistan Journal of Medical and Health Sciences"},{"issue":"Suppl 7","key":"10.1002\/14651858.CD007388.pub3-BIB0068|cit68","first-page":"S133","article-title":"Comparison of the level of magnesium during maintenance between 2 gram and 1 gram per hour infusion in overweight mothers with preeclampsia","volume":"99","author":"Kitiyodom","year":"2016","journal-title":"Journal of the Medical Association of Thailand"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0069|cit69","unstructured":"Magnesium sulfate maintenance infusion effect between 2 gram per hour and 1 gram per hour in maternal excessive weight with preeclampisa: a double-blinded randomized controlled trial http:\/\/www.clinicaltrials.in.th\/index.php?tp=regtrials&menu=trialsearch&smenu=fulltext&task=search&task2=view1&id=1270"},{"issue":"4","key":"10.1002\/14651858.CD007388.pub3-BIB0070|cit70","first-page":"281","article-title":"Comparative study of serum magnesium levels attained from magnesium sulfate therapy for severe pre-eclamptic patients between 1 gm\/hr and 2 gm\/hr regimen","volume":"11","author":"Laiteerapong","year":"1999","journal-title":"Thai Journal of Obstetrics and Gynaecology"},{"issue":"2","key":"10.1002\/14651858.CD007388.pub3-BIB0071|cit71","first-page":"76","article-title":"A comparison of serum magnesium sulfate levels in pregnant women with severe preeclampsia between intravenous and intramuscular magnesium sulfate regimens: a randomized controlled trial","volume":"79","author":"Manorot","year":"1996","journal-title":"Journal of the Medical Association of Thailand"},{"issue":"3","key":"10.1002\/14651858.CD007388.pub3-BIB0072|cit72","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.preghy.2012.04.035","article-title":"Magnesium sulfate for prevention of eclampsia: are intramuscular and intravenous regimens equivalent?","volume":"2","author":"Easterling","year":"2012","journal-title":"Pregnancy Hypertension"},{"issue":"Suppl 2","key":"10.1002\/14651858.CD007388.pub3-BIB0073|cit73","first-page":"S278","article-title":"Preeclampsia in low-resource settings: a randomized trial of IV MgSO4 via flow controlled pump","volume":"107","author":"Mundle","year":"2009","journal-title":"International Journal of Gynecology & Obstetrics"},{"issue":"1","key":"10.1002\/14651858.CD007388.pub3-BIB0074|cit74","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.preghy.2011.09.002","article-title":"Treatment approaches for preeclampsia in low-resource settings: A randomized trial of the Springfusor pump for delivery of magnesium sulfate","volume":"2","author":"Mundle","year":"2012","journal-title":"Pregnancy Hypertension"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0075|cit75","unstructured":"Treatment approaches for preeclampsia in low-resource settings https:\/\/clinicaltrials.gov\/ct2\/show\/record\/NCT00666133"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0076|cit76","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1111\/1471-0528.12222","article-title":"Magnesium sulphate for prevention of eclampsia: are intramuscular and intravenous regimens equivalent? A population pharmacokinetic study","volume":"120","author":"Salinger","year":"2013","journal-title":"BJOG: an International Journal of Obstetrics and Gynaecology"},{"issue":"2","key":"10.1002\/14651858.CD007388.pub3-BIB0077|cit77","doi-asserted-by":"crossref","first-page":"121","DOI":"10.5958\/2394-2754.2016.00034.5","article-title":"Feasibility of low dose magnesium sulphate for eclampsia \u2013 a randomized study","volume":"3","author":"Nautiyal","year":"2016","journal-title":"Indian Journal of Obstetrics and Gynecology Research"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0078|cit78","unstructured":"A trial comparing treatment with the Springfusor Infusion Pump to the IV magnesium sulfate regimen clinicaltrials.gov\/show\/NCT02091401"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0079|cit79","unstructured":"Randomized trial of magnesium sulfate in obese preeclamptic women https:\/\/clinicaltrials.gov\/ct2\/show\/record\/NCT02835339"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0080|cit80","unstructured":"Efficacy and safety of one gram versus two grams intravenous maintenance dose of magnesium sulfate in women with severe pre-eclampsia: a randomized clinical trial clinicaltrials.gov\/show\/NCT03164304"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0081|cit81","unstructured":"Use of Cheetah\u00ae Cardiac Monitoring System to guide discontinuation of magnesium sulfate in women with severe preeclampsia clinicaltrials.gov\/show\/NCT04474704"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0082|cit82","unstructured":"Low dose magnesium sulphate versus standard Pritchard regimen in management of severe preeclampsia\/eclampsia clinicaltrials.gov\/show\/NCT04501289"},{"issue":"Suppl 2","key":"10.1002\/14651858.CD007388.pub3-BIB0083|cit83","first-page":"175","article-title":"Magnesium sulphate for preeclampsia and eclampsia with Springfusor\u00ae pump versus intramuscular approach","volume":"128","author":"Ononge","year":"2021","journal-title":"BJOG: an International Journal of Obstetrics and Gynaecology"},{"issue":"Suppl 3","key":"10.1002\/14651858.CD007388.pub3-BIB0084|cit84","first-page":"S447","article-title":"Efficacy of a single loading dose of magnesium sulphate versus the standard Pritchard regimen in the management of severe preeclampsia in an African population","volume":"119","author":"Orji","year":"2012","journal-title":"International Journal of Gynecology & Obstetrics"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0085|cit85","unstructured":"Magnesium sulphate loading dose only versus standard Pritchard regimen in the management of eclampsia \u2013 a multi-centre randomized clinical trial trialsearch.who.int\/Trial2.aspx?TrialID=PACTR202201609390328"},{"issue":"3","key":"10.1002\/14651858.CD007388.pub3-BIB0086|cit86","doi-asserted-by":"crossref","first-page":"138","DOI":"10.53350\/pjmhs22163138","article-title":"Comparison of magnesium sulphate loading dose with & without maintenance regimen for management of patients presenting with eclampsia \u2013 randomized control trial","volume":"16","author":"Rahat","year":"2022","journal-title":"Pakistan Journal of Medical and Health Sciences"},{"issue":"6","key":"10.1002\/14651858.CD007388.pub3-BIB0087|cit87","first-page":"39","article-title":"Prophylactic magnesium sulphate in severe preeclampsia \u2013 loading dose only vs. conventional 24 hour therapy of modified Pritchard regime \u2013 a randomised trial","volume":"4","author":"Ranganna","year":"2014","journal-title":"IOSR Journal of Pharmacy"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0088|cit88","unstructured":"Safety and efficacy of low dose MgSo4 regimen for treatment of eclampsia ctri.nic.in\/Clinicaltrials\/pmaindet2.php?trialid=572"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0089|cit89","unstructured":"Safety and efficacy of abbreviated (12 hr) magnesium sulphate (mgso4) therapy) vs. traditional 24 hrs therapy after delivery in severe preeclampsia: a randomised clinical trial ctri.nic.in\/Clinicaltrials\/pmaindet2.php?trialid=8468"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0090|cit90","doi-asserted-by":"crossref","unstructured":"Saha PK Kaur J Goel P Kataria S Tandon R Saha L Safety and efficacy of low dose intramuscular magnesium sulphate (mgso4) compared to intravenous regimen for treatment of eclampsia Journal of Obstetrics and Gynaecology Research 2017 43 10 1543 9","DOI":"10.1111\/jog.13424"},{"issue":"1","key":"10.1002\/14651858.CD007388.pub3-BIB0091|cit91","doi-asserted-by":"crossref","first-page":"79","DOI":"10.5455\/2320-1770.ijrcog20140316","article-title":"A randomized comparative study between low-dose magnesium sulphate and standard dose regimen for management of eclampsia","volume":"3","author":"Sahu","year":"2014","journal-title":"International Journal of Reproduction, Contraception, Obstetrics and Gynecology"},{"issue":"3","key":"10.1002\/14651858.CD007388.pub3-BIB0092|cit92","doi-asserted-by":"crossref","first-page":"770","DOI":"10.18203\/2320-1770.ijrcog20150089","article-title":"Randomized comparative study between short duration (4 hour) vs. 24 hour post-partum magnesium sulphate therapy in severe preeclampsia","volume":"4","author":"Sahu","year":"2015","journal-title":"International Journal of Reproduction, Contraception, Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0093|cit93","unstructured":"Comparison of modified low dose MgSO4 regime with standard pritchard regime in severe preeclampsia and eclampsia: a randomized control trial http:\/\/www.ctri.nic.in\/Clinicaltrials\/pdf_generate.php?trialid=15615&EncHid=&modid=&compid=%27,%2715615det%27"},{"issue":"2","key":"10.1002\/14651858.CD007388.pub3-BIB0094|cit94","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.ijgo.2007.01.008","article-title":"Safety and efficacy of low-dose MgS04 in the treatment of eclampsia","volume":"97","author":"Saha","year":"2007","journal-title":"International Journal of Gynecology & Obstetrics"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0095|cit95","unstructured":"Low dose magnesium sulphate regimen for management of eclampsia \u2013 a randomized controlled trial (An ICMR Task Force Study) ctri.nic.in\/Clinicaltrials\/pmaindet2.php?trialid=153"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0096|cit96","doi-asserted-by":"crossref","unstructured":"Singh S Behera AK Eclampsia in eastern India: Incidence, demographic profile and response to three different anticonvulsant regimes of magnesium sulphate Internet Journal of Gynecology and Obstetrics 2011 15 2","DOI":"10.5580\/124a"},{"issue":"4","key":"10.1002\/14651858.CD007388.pub3-BIB0097|cit97","first-page":"504","article-title":"A prospective randomized controlled trial to individualize the duration of post partum magnesium sulfate therapy","volume":"27","author":"Suneja","year":"2008","journal-title":"Hypertension in Pregnancy"},{"issue":"7","key":"10.1002\/14651858.CD007388.pub3-BIB0098|cit98","first-page":"509","article-title":"A comparison of intravenous magnesium sulfate regimens in preeclampsia-eclampsia between rate 1 gram and 2 grams per hour","volume":"44","author":"Tongsong","year":"1992","journal-title":"Siriraj Hospital Gazette"},{"issue":"1","key":"10.1002\/14651858.CD007388.pub3-BIB0099|cit99","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/ijgo.13082","article-title":"Intravenous magnesium sulfate in the management of severe pre-eclampsia: a randomized study of 12-hour versus 24-hour maintenance dose","volume":"149","author":"Unwaha","year":"2019","journal-title":"International Journal of Gynaecology and Obstetrics"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0100|cit100","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1016\/j.ajog.2004.12.056","article-title":"A prospective randomized trial of magnesium sulfate in severe preeclampsia: use of diuresis as a clinical parameter to determine the duration of postpartum therapy","volume":"192","author":"Fontenot","year":"2005","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"1","key":"10.1002\/14651858.CD007388.pub3-BIB0101|cit101","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1080\/10641950701825721","article-title":"Prostacyclin and thromboxane levels in women with severe preeclampsia undergoing magnesium sulfate therapy during antepartum and postpartum periods","volume":"27","author":"Wang","year":"2008","journal-title":"Hypertension in Pregnancy"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0102|cit102","unstructured":"Treatment approaches for pre eclampsia in low resource settings ctri.nic.in\/Clinicaltrials\/pmaindet2.php?trialid=152"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0103|cit103","unstructured":"Comparision of two regimens of low dose magnesium sulphate for treatment of eclampsia: loading plus 24-hour maintenance dose versus loading dose only ctri.nic.in\/Clinicaltrials\/pmaindet2.php?trialid=4010"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0104|cit104","unstructured":"Low dose magnesium sulphate for treatment of seizures in pregnancy www.who.int\/trialsearch\/Trial2.aspx?TrialID=CTRI\/2021\/08\/035456"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0105|cit105","unstructured":"The STEP-Mag Trial trialsearch.who.int\/Trial2.aspx?TrialID=PACTR202112816270738 2021"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0106|cit106","unstructured":"Randomized controlled trial comparing the effectiveness and safety of 12 hours duration with the 24 hours duration of magnesium sulphate in maintenance therapy in patients of severe preeclampsia trialsearch.who.int\/Trial2.aspx?TrialID=CTRI\/2022\/01\/039776"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0107|cit107","unstructured":"Comparison treatment of magnesium sulfate for 12-hours and 24-hours in preeclampsia www.who.int\/trialsearch\/Trial2.aspx?TrialID=IRCT20200503047287N1"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0108|cit108","unstructured":"Pharmacokinetics profile of magnesium after intravenous and intramuscular magnesium sulfate administration in Indonesian pregnant women with pre-eclampsia isrctn.com\/ISRCTN13244564"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0109|cit109","unstructured":"Safety and efficacy of twelve hours duration of magnesium sulphate in the treatment of eclampsia in low resource setting in Sudan clinicaltrials.gov\/ct2\/show\/record\/NCT03112551"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0110|cit110","unstructured":"Continuation versus discontinuation of magnesium sulfate after delivery in women with severe preeclampsia. a randomized controlled trial https:\/\/clinicaltrials.gov\/ct2\/show\/record\/NCT03318211"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0111|cit111","unstructured":"Randomized trial to compare magnesium sulphate administration for preeclampsia and eclampsia: springfusor versus standard of approach https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03549767"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0112|cit112","unstructured":"Serum magnesium level between administered rate of 2 g\/hr versus 2.5 g\/hr in severe pre-eclampsia obese pregnancy, multicentered randomized study https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03661775"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0113|cit113","unstructured":"Randomized trial to compare magnesium sulphate administration for preeclampsia and eclampsia: springfusor versus standard approach https:\/\/pactr.samrc.ac.za\/TrialDisplay.aspx?TrialID=2887"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0114|cit114","unstructured":"A comparative study of modified versus standard pritchard regimen in the management of eclampsia and preeclampsia https:\/\/pactr.samrc.ac.za\/TrialDisplay.aspx?TrialID=4690"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0115|cit115","unstructured":"A comparative controlled trial of serum magnesium level in severe preeclamptic women between two standard magnesium sulphate regimens www.who.int\/trialsearch\/Trial2.aspx?TrialID=TCTR20150511001"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0116|cit116","unstructured":"Magnesium sulfate versus combination of magnesium and phentolamine for control of blood pressure in pregnancy induced hypertension www.who.int\/trialsearch\/Trial2.aspx?TrialID=JPRN-UMIN000039038"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0117|cit117","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejogrb.2013.05.005","article-title":"Global and regional estimates of preeclampsia and eclampsia:a systematic review","volume":"170","author":"Abalos","year":"2013","journal-title":"European Journal of Obstetrics and Gynecology and Reproductive Biology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0118|cit118","volume-title":"Hypertension in Pregnancy","author":"Task Force on Hypertension in Pregnancy","year":"2013"},{"issue":"f6564","key":"10.1002\/14651858.CD007388.pub3-BIB0119|cit119","first-page":"14","article-title":"Pre-eclampsia rates in the United States, 1980-2010: age-period-cohort analysis","volume":"347","author":"Ananth","year":"2013","journal-title":"BMJ"},{"issue":"8","key":"10.1002\/14651858.CD007388.pub3-BIB0120|cit120","first-page":"987.e15","article-title":"Secular trends in preeclampsia incidence and outcomes in a large Canada database: a longitudinal study over 24 years","volume":"32","author":"Auger","year":"2016","journal-title":"CJC"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0121|cit121","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S0002-9378(11)91567-1","article-title":"Effect of magnesium sulphate on maternal brain blood flow in preeclampsia: a randomised, placebo controlled study","volume":"167","author":"Belfort","year":"1992","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0122|cit122","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1111\/anae.13938","article-title":"Data fabrication and other reasons for non-random sampling in 5087 randomised, controlled trial in anaesthetic and general medical journals","volume":"72","author":"Carlisle","year":"2017","journal-title":"Anaesthesia"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0123|cit123","first-page":"309","volume-title":"Hypertensive Disorders in Pregnancy","author":"Chesley","year":"1978"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0124|cit124","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1016\/S0140-6736(95)91034-4","article-title":"Which anticonvulsant for women with eclampsia? Evidence from the Collaborative Eclampsia Trial","volume":"345","author":"The Eclampsia Trial Collaborative Group","year":"1995","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0125|cit125","first-page":"927","article-title":"Eclampsia at Harare Maternity Hospital. An epidemiological study","volume":"68","author":"Crowther","year":"1985","journal-title":"South African Medical Journal"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0126|cit126","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1001\/archneur.1988.00520360078016","article-title":"Does magnesium sulfate treat eclamptic seizures? Yes","volume":"45","author":"Dinsdale","year":"1988","journal-title":"Archives of Neurology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0127|cit127","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0959-289X(92)90023-W","article-title":"The case against magnesium sulfate for eclamptic convulsions","volume":"1","author":"Donaldson","year":"1992","journal-title":"International Journal of Obstetric Anesthesia"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0128|cit128","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0002-9378(15)32334-6","article-title":"The intramuscular injection of magnesium sulfate for the control of convulsions in eclampsia","volume":"11","author":"Dorsett","year":"1926","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0129|cit129","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1136\/bmj.309.6966.1395","article-title":"Eclampsia in the United Kingdom","volume":"309","author":"Douglas","year":"1994","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0130|cit130","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1111\/j.1471-0528.1992.tb13818.x","article-title":"Maternal mortality associated with hypertensive disorders of pregnancy in Africa, Asia, Latin America and the Caribbean","volume":"99","author":"Duley","year":"1992","journal-title":"British Journal of Obstetrics and Gynaecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0131|cit131","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1111\/j.1471-0528.1994.tb13644.x","article-title":"Magnesium sulphate for pre-eclampsia and eclampsia: the evidence so far","volume":"101","author":"Duley","year":"1994","journal-title":"British Journal of Obstetrics and Gynaecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0132|cit132","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/j.1471-0528.1996.tb09657.x","article-title":"Magnesium sulphate regimens for women with eclampsia: messages from the Collaborative Eclampsia Trial","volume":"103","author":"Duley","year":"1996","journal-title":"British Journal of Obstetrics and Gynaecology"},{"issue":"9","key":"10.1002\/14651858.CD007388.pub3-BIB0133|cit133","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002960.pub2","article-title":"Magnesium sulphate versus lytic cocktail for eclampsia","author":"Duley","year":"2010","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"12","key":"10.1002\/14651858.CD007388.pub3-BIB0134|cit134","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000127.pub2","article-title":"Magnesium sulphate versus diazepam for eclampsia","author":"Duley","year":"2010","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"10","key":"10.1002\/14651858.CD007388.pub3-BIB0135|cit135","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000128.pub2","article-title":"Magnesium sulphate versus phenytoin for eclampsia","author":"Duley","year":"2010","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"11","key":"10.1002\/14651858.CD007388.pub3-BIB0136|cit136","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000025.pub2","article-title":"Magnesium sulphate and other anticonvulsants for women with pre-eclampsia","author":"Duley","year":"2010","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0137|cit137","first-page":"562","article-title":"The management of pre-eclampsia","volume":"52","author":"Eastman","year":"1945","journal-title":"Canadian Medical Association Journal"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0138|cit138","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1056\/NEJM198811033191813","article-title":"Therapeutic use of magnesium sulfate in selected cases of cerebral ischemia and seizure","volume":"319","author":"Goldman","year":"1988","journal-title":"New England Journal of Medicine"},{"issue":"2","key":"10.1002\/14651858.CD007388.pub3-BIB0139|cit139","doi-asserted-by":"crossref","first-page":"154\u201363","DOI":"10.1016\/S1701-2163(15)30662-9","article-title":"Magnesium sulphate for the management of preeclampsia and eclampsia in low and middle income countries: a systematic review of tested dosing regimens","volume":"36","author":"Gordon","year":"2014","journal-title":"Journal of Obstetrics and Gynaecology Canada"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0140|cit140","unstructured":"Sch\u00fcnemann H Bro\u017cek J Guyatt G Oxman A Handbook for grading the quality of evidence and the strength of recommendations using the GRADE approach (updated October 2013). GRADE Working Group, 2013 Available from gdt.guidelinedevelopment.org\/app\/handbook\/handbook.html"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0141|cit141","unstructured":"GRADEpro GDT McMaster University (developed by Evidence Prime)"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0142|cit142","unstructured":"Higgins JPT Green S Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from training.cochrane.org\/handbook\/archive\/v5.1\/"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0143|cit143","unstructured":"Higgins JPT Thomas J Chandler J Cumpston M Li T Page MJ Cochrane Handbook for Systematic Reviews of Interventions version 6.4 (updated August 2023). Cochrane, 2023 Available from www.training.cochrane.org\/handbook"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0144|cit144","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1001\/archneur.1988.00520360079017","article-title":"No, magnesium sulfate should not be used in treating eclamptic seizures","volume":"45","author":"Kaplan","year":"1988","journal-title":"Archives of Neurology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0145|cit145","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/S0140-6736(06)68397-9","article-title":"WHO analysis of causes of maternal death: a systematic review","volume":"367","author":"Khan","year":"2006","journal-title":"Lancet"},{"issue":"9","key":"10.1002\/14651858.CD007388.pub3-BIB0146|cit146","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1111\/j.1471-0528.2007.01423.x","article-title":"Eclampsia in the United Kingdom 2005","volume":"114","author":"Knight","year":"2007","journal-title":"BJOG: an International Journal of Obstetrics and Gynaecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0147|cit147","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S0002-9378(25)90068-3","article-title":"A preliminary report on the intravenous use of magnesium sulphate in puerperal eclampsia","volume":"9","author":"Lazard","year":"1925","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0148|cit148","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1111\/j.1471-0528.1968.tb01605.x","article-title":"The use of chlordiazepoxide in patients with severe pregnancy toxaemia. (A preliminary study of effects on the newborn infants)","volume":"75","author":"Lean","year":"1968","journal-title":"Journal of Obstetrics and Gynaecology of the British Commonwealth"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0149|cit149","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1016\/S0140-6736(02)08778-0","article-title":"Do women with pre-eclampsia, and their babies, benefit from magnesium sulphate? The Magpie Trial: a randomised placebo-controlled trial","volume":"359","author":"Magpie Trial Collaboration Group","year":"2002","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0150|cit150","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1016\/j.ajog.2004.02.037","article-title":"Delayed postpartum preeclampsia: an experience of 151 cases","volume":"90","author":"Matthys","year":"2004","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"2","key":"10.1002\/14651858.CD007388.pub3-BIB0151|cit151","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005301","article-title":"Interventions for preventing pre-eclampsia and its consequences: generic protocol","author":"Meher","year":"2005","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0152|cit152","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/S0140-6736(15)00070-7","article-title":"Pre-eclampsia","volume":"387(10022)","author":"Mol","year":"2016","journal-title":"Lancet"},{"issue":"2","key":"10.1002\/14651858.CD007388.pub3-BIB0153|cit153","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/aogs.12807","article-title":"Alternative regimens of magnesium sulfate for treatment of preeclampsia and eclampsia: a systematic review of non-randomized studies","volume":"95","author":"Pratt","year":"2016","journal-title":"Acta Obstetricia Gynecologica Scandinavica"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0154|cit154","first-page":"131","article-title":"The use of magnesium ion in the management of eclamptogenic toxemias","volume":"100","author":"Pritchard","year":"1955","journal-title":"Surgery, Gynecology and Obstetrics"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0155|cit155","unstructured":"Review Manager (RevMan) The Cochrane Collaboration 2020"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0156|cit156","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1161\/01.STR.20.9.1273","article-title":"Action of magnesium sulfate in the treatment of preeclampsia-eclampsia","volume":"20","author":"Sadeh","year":"1989","journal-title":"Stroke"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0157|cit157","first-page":"261","article-title":"Effect of magnesium sulfate on electroencephalographic findings in preeclampsia-eclampsia","volume":"64","author":"Sibai","year":"1984","journal-title":"Obstetrics & Gynecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0158|cit158","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/0002-9378(90)90002-O","article-title":"Magnesium sulfate is the ideal anticonvulsant in preeclampsia-eclampsia","volume":"162","author":"Sibai","year":"1990","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0159|cit159","doi-asserted-by":"crossref","first-page":"144\u201351","DOI":"10.1111\/j.1471-0528.2005.00785.x","article-title":"Cost-effectiveness of prophylactic magnesium sulphate for 9996 women with pre-eclampsia from 33 countries: economic evaluation of the Magpie Trial","volume":"113","author":"Simon","year":"2006","journal-title":"BJOG: an International Journal of Obstetrics and Gynaecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0160|cit160","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1016\/S0140-6736(87)90603-9","article-title":"Phenytoin infusion in severe pre-eclampsia","volume":"i","author":"Slater","year":"1987","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0161|cit161","first-page":"289","article-title":"Two hundred cases of eclampsia treated with magnesium sulphate. A preliminary report","volume":"44","author":"Stroganoff","year":"1937","journal-title":"Journal of Obstetrics and Gynaecology"},{"issue":"6","key":"10.1002\/14651858.CD007388.pub3-BIB0162|cit162","doi-asserted-by":"crossref","first-page":"476.e1","DOI":"10.1016\/j.ajog.2013.02.042","article-title":"The incidence of preeclampsia and eclampsia and associated maternal mortality in Australia from population-linked datasets: 2000-2008","volume":"208","author":"Thornton","year":"2013","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0163|cit163","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/0002-9378(88)90782-X","article-title":"Geographic variation in the incidence of hypertension in pregnancy","volume":"158","author":"World Health Organization International Collaborative Study","year":"1988","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0164|cit164","volume-title":"WHO Recommendations for Prevention and Treatment of Pre-eclampsia and Eclampsia","author":"World Health Organization","year":"2011"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0165|cit165","doi-asserted-by":"crossref","first-page":"e323\u201333","DOI":"10.1016\/S2214-109X(14)70227-X","article-title":"Global causes of maternal death: a WHO systematic analysis. Global causes of maternal death: a WHO systematic analysis","volume":"2","author":"Say","year":"2014","journal-title":"Lancet Global Health"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0166|cit166","unstructured":"World Health Organization WHO recommendations on antiplatelet agents for the prevention of pre-eclampsia. Licence: CC BY-NC-SA 3.L0 IGO World Health Organization 2021"},{"key":"10.1002\/14651858.CD007388.pub3-BIB0167|cit167","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/0002-9378(78)90816-5","article-title":"Problems encountered in the treatment of pregnancy-induced hypertension","volume":"131","author":"Zuspan","year":"1978","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"8","key":"10.1002\/14651858.CD007388.pub3-BIB0168|cit168","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007388.pub2","article-title":"Alternative magnesium sulphate regimens for women with pre-eclampsia and eclampsia","author":"Duley","year":"2010","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T00:06:07Z","timestamp":1771200367000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD007388.pub3"}},"subtitle":[],"editor":[{"name":"Cochrane Pregnancy and Childbirth Group","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,10,10]]},"references-count":168,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2023,10]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd007388.pub3","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,10]]}}}