{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T05:34:37Z","timestamp":1792301677070,"version":"4.4.0"},"update-to":[{"DOI":"10.1002\/14651858.cd007543","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2012,6,13]],"date-time":"2012-06-13T00:00:00Z","timestamp":1339545600000}}],"reference-count":35,"publisher":"Wiley","issue":"6","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd007543.pub2","type":"journal-article","created":{"date-parts":[[2012,6,8]],"date-time":"2012-06-08T11:04:40Z","timestamp":1339153480000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":251,"title":["Enhanced glucose control for preventing and treating diabetic neuropathy"],"prefix":"10.1002","volume":"2012","author":[{"given":"Brian C","family":"Callaghan","sequence":"first","affiliation":[{"name":"University of Michigan; Department of Neurology; 5017 BSRB 109 Zina Pitcher Road Ann Arbor Michigan USA MI 48109-2200"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann A","family":"Little","sequence":"additional","affiliation":[{"name":"University of Michigan; Department of Neurology; 5017 BSRB 109 Zina Pitcher Road Ann Arbor Michigan USA MI 48109-2200"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva L","family":"Feldman","sequence":"additional","affiliation":[{"name":"University of Michigan; Department of Neurology; 5017 BSRB 109 Zina Pitcher Road Ann Arbor Michigan USA MI 48109-2200"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard AC","family":"Hughes","sequence":"additional","affiliation":[{"name":"National Hospital for Neurology and Neurosurgery; MRC Centre for Neuromuscular Diseases; PO Box 114 Queen Square London UK WC1N 3BG"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,6,13]]},"reference":[{"issue":"9739","key":"10.1002\/14651858.CD007543.pub2-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0140-6736(10)60576-4","article-title":"Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial","volume":"376","author":"Ismail-Beigi","year":"2010","journal-title":"Lancet"},{"issue":"5-6","key":"10.1002\/14651858.CD007543.pub2-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"307\u201313","DOI":"10.1016\/S1056-8727(99)00062-8","article-title":"The effects of intensive glycemic control on neuropathy in the VA Cooperative Study on Type II Diabetes Mellitus (VA CSDM)","volume":"13","author":"Azad","year":"1999","journal-title":"Journal of Diabetes and Its Complications"},{"issue":"6","key":"10.1002\/14651858.CD007543.pub2-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/BF00403376","article-title":"The effect of 8 years of strict glycaemic control on peripheral nerve function in IDDM patients: the Oslo study","volume":"37","author":"Amthor","year":"1994","journal-title":"Diabetologia"},{"issue":"6556","key":"10.1002\/14651858.CD007543.pub2-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1136\/bmj.293.6556.1195","article-title":"Effect of near normoglycaemia for two years on progression of early diabetic retinopathy, nephropathy, and neuropathy: the Oslo study","volume":"293","author":"Dahl-J\u00f8rgensen","year":"1986","journal-title":"British Medical Journal"},{"issue":"6","key":"10.1002\/14651858.CD007543.pub2-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1002\/ana.410380607","article-title":"Effect of intensive diabetes treatment on nerve conduction in the Diabetes Control and Complications Trial","volume":"38","author":"Diabetes Control and Complications Trial (DCCT) Research Group","year":"1995","journal-title":"Annals of Neurology"},{"issue":"14","key":"10.1002\/14651858.CD007543.pub2-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1056\/NEJM199309303291401","article-title":"The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus","volume":"329","author":"The Diabetes Control and Complications Trial Research Group","year":"1993","journal-title":"New England Journal of Medicine"},{"issue":"14","key":"10.1002\/14651858.CD007543.pub2-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1056\/NEJM199309303291401","article-title":"The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus","volume":"329","author":"The Diabetes Control and Complications Trial Research Group","year":"1993","journal-title":"New England Journal of Medicine"},{"issue":"2","key":"10.1002\/14651858.CD007543.pub2-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1056\/NEJMoa0808431","article-title":"Glucose control and vascular complications in veterans with type 2 diabetes","volume":"360","author":"Duckworth","year":"2009","journal-title":"New England Journal of Medicine"},{"issue":"5","key":"10.1002\/14651858.CD007543.pub2-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1056\/NEJMoa021778","article-title":"Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes","volume":"348","author":"Gaede","year":"2003","journal-title":"New England Journal of Medicine"},{"issue":"8318","key":"10.1002\/14651858.CD007543.pub2-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/S0140-6736(83)92586-2","article-title":"Prevention of deterioration of renal and sensory-nerve function by more intensive management of insulin-dependent diabetic patients: a two-year randomised prospective study","volume":"321","author":"Holman","year":"1983","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD007543.pub2-BIB0011|cit11","first-page":"91S","article-title":"Diabetic neuropathy: effects of intensified glycaemic control with multiple insulin injections","volume":"10 (Suppl 2)","author":"Hotta","year":"1993","journal-title":"Diabetic Medicine"},{"issue":"4","key":"10.1002\/14651858.CD007543.pub2-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"452","DOI":"10.2337\/diab.37.4.452","article-title":"Autonomic and somatosensory nerve function after 2 years of continuous subcutaneous insulin infusion in type I diabetes","volume":"37","author":"Jakobsen","year":"1988","journal-title":"Diabetes"},{"issue":"6","key":"10.1002\/14651858.CD007543.pub2-BIB0013|cit13","doi-asserted-by":"crossref","first-page":"618","DOI":"10.2169\/internalmedicine1962.30.618","article-title":"Determination of the glycemic threshold for the regression or prevention of diabetic microangiopathies, and the insulin injection regimen to establish strict glycemic control in NIDDM","volume":"30","author":"Kawamori","year":"1991","journal-title":"Japanese Journal of Medicine"},{"issue":"Suppl 3","key":"10.1002\/14651858.CD007543.pub2-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"74","DOI":"10.2337\/diab.34.3.S74","article-title":"Two-year experience with continuous subcutaneous insulin infusion in relation to retinopathy and neuropathy","volume":"34","author":"Lauritzen","year":"1985","journal-title":"Diabetes"},{"issue":"12","key":"10.1002\/14651858.CD007543.pub2-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1016\/S0026-0495(96)90180-8","article-title":"Intensive therapy in adult insulin-dependent diabetes mellitus Is associated with improved insulin sensitivity and reserve: a randomized, controlled, prospective study over 5 years in newly diagnosed patients","volume":"45","author":"Linn","year":"1996","journal-title":"Metabolism: Clinical and Experimental"},{"issue":"5","key":"10.1002\/14651858.CD007543.pub2-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1056\/NEJM199307293290502","article-title":"The effect of long-term intensified insulin treatment on the development of microvascular complications of diabetes mellitus","volume":"329","author":"Reichard","year":"1993","journal-title":"New England Journal of Medicine"},{"issue":"5","key":"10.1002\/14651858.CD007543.pub2-BIB0017|cit17","first-page":"283","article-title":"Effect of blood glucose control on peripheral nerve function in diabetic patients","volume":"58","author":"Service","year":"1983","journal-title":"Mayo Clinic Proceedings"},{"key":"10.1002\/14651858.CD007543.pub2-BIB0018|cit18","first-page":"B21","article-title":"Long-term results of the Kumamoto study on optimal diabetes control in type 2 diabetic patients","volume":"23 (Suppl 2)","author":"Shichiri","year":"2000","journal-title":"Diabetes Care"},{"issue":"5","key":"10.1002\/14651858.CD007543.pub2-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/j.1600-0404.1998.tb01746.x","article-title":"Diabetic neuropathy in elderly type 2 diabetic patients: effects of insulin treatment","volume":"98","author":"Tovi","year":"1998","journal-title":"Acta Neurologica Scandinavica"},{"issue":"9131","key":"10.1002\/14651858.CD007543.pub2-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S0140-6736(98)07019-6","article-title":"Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)","volume":"352","author":"UK Prospective Diabetes Study (UKPDS) Group","year":"1998","journal-title":"Lancet"},{"issue":"6","key":"10.1002\/14651858.CD007543.pub2-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1002\/(SICI)1096-9136(199806)15:6<508::AID-DIA613>3.0.CO;2-L","article-title":"Guidelines for the diagnosis and outpatient management of diabetic peripheral neuropathy","volume":"15","author":"Boulton","year":"1998","journal-title":"Diabetes Medicine"},{"issue":"6","key":"10.1002\/14651858.CD007543.pub2-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.2337\/diacare.27.6.1458","article-title":"Diabetic somatic neuropathies (technical review)","volume":"27","author":"Boulton","year":"2004","journal-title":"Diabetes Care"},{"issue":"6","key":"10.1002\/14651858.CD007543.pub2-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.2337\/diabetes.54.6.1615","article-title":"The pathobiology of diabetic complications","volume":"54","author":"Brownlee","year":"2005","journal-title":"Diabetes"},{"key":"10.1002\/14651858.CD007543.pub2-BIB0024|cit24","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1002\/ana.410380607","article-title":"Effect of intensive diabetes treatment on nerve conduction in the Diabetes Control and Complications Trial","volume":"38","author":"Diabetes Control and Complications Trial (DCCT) Research Group","year":"1995","journal-title":"Annals of Neurology"},{"key":"10.1002\/14651858.CD007543.pub2-BIB0025|cit25","first-page":"170","article-title":"Severity and staging of diabetic polyneuropathy","volume-title":"Textbook of Diabetic Neuropathy","author":"Dyck","year":"2003"},{"key":"10.1002\/14651858.CD007543.pub2-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1016\/B978-0-7216-9491-7.50043-0","article-title":"Quantitating overall neuropathic symptoms, impairments, and outcomes","volume-title":"Peripheral Neuropathy","author":"Dyck","year":"2005"},{"issue":"11","key":"10.1002\/14651858.CD007543.pub2-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"3160","DOI":"10.2337\/diacare.26.11.3160","article-title":"Follow-up report on the diagnosis of diabetes mellitus","volume":"26","author":"Genuth","year":"2003","journal-title":"Diabetes Care"},{"issue":"2","key":"10.1002\/14651858.CD007543.pub2-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"217","DOI":"10.2337\/diabetes.50.2.217","article-title":"The discovery of type I diabetes","volume":"50","author":"Gale","year":"2001","journal-title":"Diabetes"},{"issue":"2","key":"10.1002\/14651858.CD007543.pub2-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1007\/s11910-010-0093-7","article-title":"Therapeutic strategies for diabetic neuropathy","volume":"10","author":"Habib","year":"2010","journal-title":"Current Neurology and Neuroscience Reports"},{"key":"10.1002\/14651858.CD007543.pub2-BIB0030|cit30","unstructured":"Higgins JPT Altman DG Sterne JAC (editors) Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011) The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org"},{"issue":"5","key":"10.1002\/14651858.CD007543.pub2-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1046\/j.1464-5491.2002.00698.x","article-title":"The North-West Diabetes Foot Care Study:\u00a0incidence of, and risk factors for, new diabetic foot ulceration in a community-based patient cohort","volume":"19","author":"Abbott","year":"2002","journal-title":"Diabetic Medicine"},{"issue":"2","key":"10.1002\/14651858.CD007543.pub2-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1056\/NEJM199507133330203","article-title":"Natural history of peripheral neuropathy in patients with non-insulin-dependent diabetes mellitus","volume":"333","author":"Partanen","year":"1995","journal-title":"New England Journal of Medicine"},{"issue":"2","key":"10.1002\/14651858.CD007543.pub2-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S1098-3597(01)90027-4","article-title":"Glycemic control in the prevention of diabetic complications","volume":"4","author":"Ratner","year":"2001","journal-title":"Clinical Cornerstone"},{"issue":"3 Suppl","key":"10.1002\/14651858.CD007543.pub2-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.amjmed.2009.12.004","article-title":"Glycemic control and complications in type 2 diabetes mellitus","volume":"123","author":"Stolar","year":"2010","journal-title":"American Journal of Medicine"},{"issue":"5","key":"10.1002\/14651858.CD007543.pub2-BIB0035|cit35","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.2337\/diacare.26.5.1553","article-title":"Diabetic autonomic neuropathy","volume":"26","author":"Vinik","year":"2003","journal-title":"Diabetes Care"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/14651858.CD007543.pub2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T07:32:15Z","timestamp":1729582335000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD007543.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Neuromuscular Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2012,6,13]]},"references-count":35,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2012,6]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd007543.pub2","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,13]]}}}