{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T23:18:01Z","timestamp":1791415081492,"version":"4.3.3"},"update-to":[{"DOI":"10.1002\/14651858.cd008684.pub2","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2021,2,3]],"date-time":"2021-02-03T00:00:00Z","timestamp":1612310400000}}],"reference-count":142,"publisher":"Wiley","issue":"2","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd008684.pub3","type":"journal-article","created":{"date-parts":[[2021,2,6]],"date-time":"2021-02-06T10:23:06Z","timestamp":1612606986000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Coenzyme Q10 for heart failure"],"prefix":"10.1002","volume":"2021","author":[{"given":"Tareq","family":"Al Saadi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine; University of Illinois at Chicago\/Advocate Christ Medical Center; Oak Lawn Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazan","family":"Assaf","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases; Mayo Clinic; Rochester USA"},{"name":"Department of Medicine; University of Florida; Gainesville USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Medhat","family":"Farwati","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases; Mayo Clinic; Rochester USA"},{"name":"Department of Internal Medicine; Cleveland Clinic Foundation; Cleveland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Turkmani","sequence":"additional","affiliation":[{"name":"Department of Surgery; AlKalamoon General Hospital; AlNabek Syrian Arab Republic"},{"name":"Faculty of Medicine; Syrian Private University; Damascus Syrian Arab Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Al-Mouakeh","sequence":"additional","affiliation":[{"name":"Faculty of Medicine; University of Aleppo; Aleppo Syrian Arab Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baraa","family":"Shebli","sequence":"additional","affiliation":[{"name":"Faculty of Medicine; University of Aleppo; Aleppo Syrian Arab Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Khoja","sequence":"additional","affiliation":[{"name":"ENT Department; Al Razi Public Hospital; Aleppo Syrian Arab Republic"},{"name":"Medical Education Program; Syrian Virtual University; Damascus Syrian Arab Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adib","family":"Essali","sequence":"additional","affiliation":[{"name":"Community Mental Health; Counties Manukau Health; Manukau New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed E","family":"Madmani","sequence":"additional","affiliation":[{"name":"Department of Medicine, Cardiology Division; University of Arkansas for Medical Sciences; Little Rock USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,3]]},"reference":[{"issue":"10","key":"10.1002\/14651858.CD008684.pub3-BIB0001|cit1","first-page":"A26","article-title":"Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study","volume":"27","author":"Berman","year":"2004","journal-title":"Clinical Cardiology"},{"issue":"5","key":"10.1002\/14651858.CD008684.pub3-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/clc.4960270512","article-title":"Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study","volume":"27","author":"Berman","year":"2004","journal-title":"Clinical Cardiology"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0003|cit3","unstructured":"Effect of the REduced form of COenzyme Q10 Supplementation on endothelial function in chronic heart failure (RECOQS) apps.who.int\/trialsearch\/Trial2.aspx?TrialID=JPRN-UMIN000012604"},{"issue":"4","key":"10.1002\/14651858.CD008684.pub3-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s40256-019-00384-y","article-title":"Ubiquinol\u00a0improves endothelial function in patients with heart failure with reduced ejection fraction: a single-center, randomized double-blind placebo-controlled crossover pilot study","volume":"20","author":"Akiyama","year":"2020","journal-title":"American Journal of Cardiovascular Drugs"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD008684.pub3-BIB0005|cit5","first-page":"Abstract 14946","article-title":"Ubiquinol\u00a0improves endothelial function in patients with heart failure with reduced ejection fraction: a single center, randomized double-blind placebo-controlled cross-over study","volume":"134","author":"Kawashima","year":"2016","journal-title":"Circulation"},{"issue":"3","key":"10.1002\/14651858.CD008684.pub3-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1046\/j.1443-9506.2003.00189.x","article-title":"Randomised double-blind, placebo-controlled trial of coenzyme Q10 therapy in class II and III systolic heart failure","volume":"12","author":"Keogh","year":"2003","journal-title":"Heart, Lung and Circulation"},{"issue":"8","key":"10.1002\/14651858.CD008684.pub3-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"636","DOI":"10.7326\/0003-4819-132-8-200004180-00006","article-title":"The effect of coenzyme Q10 in patients with congestive heart failure","volume":"132","author":"Khatta","year":"2000","journal-title":"Annals of Internal Medicine"},{"issue":"5","key":"10.1002\/14651858.CD008684.pub3-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1017\/S1047951109990795","article-title":"Coenzyme Q10 improves diastolic function in children with idiopathic dilated cardiomyopathy","volume":"19","author":"Kocharian","year":"2009","journal-title":"Cardiology in the Young"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0009|cit9","unstructured":"Coenzyme Q10 supplementation in children with idiopathic dilated cardiomyopathy clinicaltrials.gov\/show\/nct02115581"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD008684.pub3-BIB0010|cit10","first-page":"56","article-title":"Coenzyme Q-10 in treatment of patients with heart failure: results Russian multicenter double blind placebo controlled study","volume":"19","author":"Mareev","year":"2017","journal-title":"European Journal of Heart Failure"},{"issue":"8 Suppl","key":"10.1002\/14651858.CD008684.pub3-BIB0011|cit11","first-page":"S134","article-title":"Effect of coenzyme Q10 therapy in patients with congestive heart failure: a long-term multicenter randomized study","volume":"71","author":"Morisco","year":"1993","journal-title":"Clinical Investigator"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0012|cit12","unstructured":"Coenzyme Q10 as adjunctive treatment of chronic heart failure. A randomised double-blind multicenter trial with focus on symptoms, biomarker status (BNP) and long-term outcome (hospitalisation\/mortality)\u00a0(Q-Symbio) www.who.int\/trialsearch\/Trial2.aspx?TrialID=EUCTR2005-002960-27-HU"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0013|cit13","unstructured":"Coenzyme Q10 as adjunctive treatment of chronic heart failure: a randomised, double-blind, multicentre trial with focus on SYMptoms, BIOmarker status (Brain-Natriuretic Peptide (BNP)), and long-term outcome (hospitalisations\/mortality) www.isrctn.com\/ISRCTN94506234"},{"issue":"2","key":"10.1002\/14651858.CD008684.pub3-BIB0014|cit14","first-page":"147","article-title":"Effect of coenzyme Q10 in Europeans with chronic heart failure: a sub-group analysis of the Q-SYMBIO randomized double-blind trial","volume":"26","author":"Mortensen","year":"2019","journal-title":"Cardiology Journal"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0015|cit15","first-page":"659","article-title":"Is the therapeutic efficacy of coenzyme Q10 replicated in a geographical subgroup of the Q-SYMBIO study?","volume":"36","author":"Mortensen","year":"2015","journal-title":"European Heart Journal"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"A55","DOI":"10.1136\/heartjnl-2013-303992.168","article-title":"Long-term results with coenzyme Q10 as adjunctive therapy in chronic heart failure","volume":"99","author":"Mortensen","year":"2013","journal-title":"Heart"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0017|cit17","first-page":"S21","article-title":"The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure. Results from the Q-SYMBIO study","volume":"12","author":"Mortensen","year":"2013","journal-title":"European Journal of Heart Failure"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1016\/j.cardfail.2013.06.085","article-title":"Coenzyme Q10 therapy blocks the vicious metabolic cycle in chronic heart failure","volume":"1","author":"Mortensen","year":"2013","journal-title":"Journal of Cardiac Failure"},{"issue":"6","key":"10.1002\/14651858.CD008684.pub3-BIB0019|cit19","first-page":"641","article-title":"The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial","volume":"2","author":"Mortensen","year":"2014","journal-title":"JACC: Heart Failure"},{"issue":"2-4","key":"10.1002\/14651858.CD008684.pub3-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/biof.5520090225","article-title":"Coenzyme Q10 treatment in serious heart failure","volume":"9","author":"Munkholm","year":"1999","journal-title":"Biofactors"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0021|cit21","unstructured":"Coenzyme Q10 supplementation in heart failure with preserved ejection fraction patients www.isrctn.com\/ISRCTN96610559"},{"issue":"1","key":"10.1002\/14651858.CD008684.pub3-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"38","DOI":"10.5582\/ddt.2019.01004","article-title":"Effects of coenzyme Q10 supplementation on diastolic function in patients with heart failure with preserved ejection fraction","volume":"13","author":"Sobirin","year":"2019","journal-title":"Drug Discoveries & Therapeutics"},{"issue":"2","key":"10.1002\/14651858.CD008684.pub3-BIB0023|cit23","first-page":"e209","article-title":"Effect of coenzyme Q10 administration on the incidence of atrial fibrillation in patients with heart failure","volume":"122","author":"Qingyan","year":"2010","journal-title":"Circulation"},{"issue":"5","key":"10.1002\/14651858.CD008684.pub3-BIB0024|cit24","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1097\/JIM.0000000000000202","article-title":"Effect of coenzyme Q10 on the incidence of atrial fibrillation in patients with heart failure","volume":"63","author":"Zhao","year":"2015","journal-title":"Journal of Investigative Medicine"},{"issue":"1-4","key":"10.1002\/14651858.CD008684.pub3-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/biof.5520320117","article-title":"Coenzyme Q10 (CoQ10) in isolated diastolic heart failure in hypertrophic cardiomyopathy (HCM)","volume":"32","author":"Adarsh","year":"2008","journal-title":"BioFactors (Oxford, England)"},{"issue":"1","key":"10.1002\/14651858.CD008684.pub3-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1253\/jcj.56.95","article-title":"Usefulness of taurine in chronic congestive heart failure and its prospective application","volume":"56","author":"Azuma","year":"1992","journal-title":"Japanese Circulation Journal"},{"issue":"8 Suppl","key":"10.1002\/14651858.CD008684.pub3-BIB0027|cit27","first-page":"S145","article-title":"Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure (interim analysis)","volume":"71","author":"Baggio","year":"1993","journal-title":"Clinical Investigator"},{"issue":"1-4","key":"10.1002\/14651858.CD008684.pub3-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1002\/biof.5520250115","article-title":"Coenzyme Q10 improves contractility of dysfunctional myocardium in chronic heart failure","volume":"25","author":"Belardinelli","year":"2005","journal-title":"Biofactors"},{"issue":"1-4","key":"10.1002\/14651858.CD008684.pub3-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/biof.5520320115","article-title":"Oxidative stress, endothelial function and coenzyme Q10","volume":"32","author":"Belardinelli","year":"2008","journal-title":"Biofactors"},{"issue":"5","key":"10.1002\/14651858.CD008684.pub3-BIB0030|cit30","first-page":"43S","article-title":"Treatment of patients with congestive heart failure with coenzyme Q10 in an open trial","volume":"124","author":"Cascone","year":"1985","journal-title":"Bollettino Chimico Farmaceutico"},{"issue":"34","key":"10.1002\/14651858.CD008684.pub3-BIB0031|cit31","first-page":"4334","article-title":"Research progress on correlation and intervention of micronutrients and chronic heart failure","volume":"31","author":"Yuanyuan","year":"2017","journal-title":"Chinese Nursing Research"},{"issue":"11","key":"10.1002\/14651858.CD008684.pub3-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"07","DOI":"10.3390\/nu10111697","article-title":"A pilot clinical study of liquid ubiquinol\u00a0supplementation on cardiac function in pediatric\u00a0dilated cardiomyopathy","volume":"10","author":"Chen","year":"2018","journal-title":"Nutrients"},{"issue":"8","key":"10.1002\/14651858.CD008684.pub3-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.2337\/dc08-0118","article-title":"Hemodynamic effects of fenofibrate and coenzyme Q10 in type 2 diabetic subjects with left ventricular diastolic dysfunction","volume":"31","author":"Chew","year":"2008","journal-title":"Diabetes Care"},{"issue":"11","key":"10.1002\/14651858.CD008684.pub3-BIB0034|cit34","first-page":"449","article-title":"Coenzyme Q10: contractile dysfunction of the myocardial cell and metabolic therapy","volume":"40","author":"Davini","year":"1992","journal-title":"Minerva Cardioangiologica"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0035|cit35","first-page":"369","article-title":"Influence of coenzyme Q10 supplementation in statin treated patients on left ventricular diastolic dysfunction. Results of randomised double-blind clinical study","volume":"30","author":"Fedacko","year":"2009","journal-title":"European Heart Journal"},{"issue":"4","key":"10.1002\/14651858.CD008684.pub3-BIB0036|cit36","first-page":"675","article-title":"Long-term survival in coenzyme Q10 treated congestive-heart-failure patients","volume":"82","author":"Hall","year":"1990","journal-title":"Circulation"},{"issue":"4","key":"10.1002\/14651858.CD008684.pub3-BIB0037|cit37","first-page":"323","article-title":"The changes of PRA, ATII, ALD, ET and ANP in patients with left ventricular and intervention with enalapril","volume":"22","author":"Hanping","year":"1997","journal-title":"Bulletin of Hunan Medical University"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/1071-9164(95)90011-X","article-title":"Coenzyme Q10 as an adjunctive in the treatment of chronic congestive heart failure","volume":"1","author":"Hofman-Bang","year":"1995","journal-title":"Journal of Cardiac Failure"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0039|cit39","unstructured":"Effect of Q10 coenzyme in improving cardiac function en.irct.ir\/trial\/19746"},{"issue":"1","key":"10.1002\/14651858.CD008684.pub3-BIB0040|cit40","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1536\/ihj.17.32","article-title":"A clinical study of the effect of coenzyme Q on congestive heart failure","volume":"17","author":"Ishiyama","year":"1976","journal-title":"Japanese Heart Journal"},{"issue":"9","key":"10.1002\/14651858.CD008684.pub3-BIB0041|cit41","first-page":"2604","article-title":"Clinical efficacy of coenzyme Q10 for cardiac failure: a double-blind controlled comparison","volume":"49","author":"Iwabuchi","year":"1972","journal-title":"Rinsho to Kenkyu (Japanese Journal of Clinical and Experimental Medicine)"},{"issue":"5","key":"10.1002\/14651858.CD008684.pub3-BIB0042|cit42","doi-asserted-by":"crossref","first-page":"281","DOI":"10.3109\/14017431.2013.820838","article-title":"Effect of selenium and Q10 on the cardiac biomarker NT-proBNP","volume":"47","author":"Johansson","year":"2013","journal-title":"Scandinavian Cardiovascular Journal"},{"issue":"9","key":"10.1002\/14651858.CD008684.pub3-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1007\/s12603-015-0509-9","article-title":"Improved health-related quality of life, and more days out of hospital with supplementation with selenium and coenzyme Q10 combined. Results from a double blind, placebo-controlled prospective study","volume":"19","author":"Johansson","year":"2015","journal-title":"Journal of Nutrition Health & Aging"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0044|cit44","unstructured":"Comparison of effects of pitavastatin and rosuvastatin on patients with chronic heart failure www.who.int\/trialsearch\/Trial2.aspx?TrialID=JPRN-UMIN000007695"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0045|cit45","unstructured":"Study of a heart failure treatment using a combination drug consisting of reduced coenzyme Q10, astaxanthin, citrulline, and zinc www.who.int\/trialsearch\/Trial2.aspx?TrialID=JPRN-UMIN000020203"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0046|cit46","unstructured":"Effects of reduced form of coenzyme Q10 (ubiquinol) on heart failure and arrhythmias www.who.int\/trialsearch\/Trial2.aspx?TrialID=JPRN-UMIN000027248"},{"issue":"18","key":"10.1002\/14651858.CD008684.pub3-BIB0047|cit47","first-page":"3411","article-title":"Long-term efficacy of coenzyme Q10 therapy for congestive heart failure","volume":"100","author":"Khatta","year":"1999","journal-title":"Circulation"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0048|cit48","first-page":"109","article-title":"Analysis of changes of ECHO-cardiogram indices in patients with chronic heart failure during therapy with coenzyme Q10","volume":"18","author":"Kukharchik","year":"2016","journal-title":"European Journal of Heart Failure"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0049|cit49","first-page":"399","article-title":"Some aspects of the effect of coenzyme Q10 on inflammatory processes, remodeling and functional status of endothelium in chronic heart failure","volume":"18","author":"Kukharchik","year":"2016","journal-title":"European Journal of Heart Failure"},{"issue":"16","key":"10.1002\/14651858.CD008684.pub3-BIB0050|cit50","doi-asserted-by":"crossref","first-page":"C145","DOI":"10.1016\/j.jacc.2017.07.525","article-title":"The effect of coenzyme Q10 on the content of proinflammatory makers and the realization of the mitochondrial mechanism of apoptosis in chronic heart failure","volume":"70","author":"Kukharchik","year":"2017","journal-title":"Journal of the American College of Cardiology"},{"issue":"4","key":"10.1002\/14651858.CD008684.pub3-BIB0051|cit51","doi-asserted-by":"crossref","first-page":"349","DOI":"10.2143\/AC.62.4.2022278","article-title":"Effect of carni Q-gel (ubiquinol and carnitine) on cytokines in patients with heart failure in the Tishcon study","volume":"62","author":"Kumar","year":"2007","journal-title":"Acta Cardiologica"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0052|cit52","first-page":"345","article-title":"Coenzyme Q10 as an adjuvant therapy in heart failure (HF)","volume":"131","author":"Kumar","year":"2015","journal-title":"Cardiology"},{"issue":"8","key":"10.1002\/14651858.CD008684.pub3-BIB0053|cit53","first-page":"S129","article-title":"Italian multicenter study on the efficacy and safety of coenzyme Q10 as adjuvant therapy in heart-failure","volume":"71","author":"Lampertico","year":"1993","journal-title":"Clinical Investigator"},{"issue":"8","key":"10.1002\/14651858.CD008684.pub3-BIB0054|cit54","first-page":"577","article-title":"Effective treatment with coenzyme Q10 of patients with chronic myocardial disease","volume":"11","author":"Langsjoen","year":"1985","journal-title":"Drugs Under Experimental & Clinical Research"},{"issue":"12","key":"10.1002\/14651858.CD008684.pub3-BIB0055|cit55","doi-asserted-by":"crossref","first-page":"4240","DOI":"10.1073\/pnas.82.12.4240","article-title":"Response of patients in classes III and IV of cardiomyopathy to therapy in a blind and crossover trial with coenzyme Q10","volume":"82","author":"Langsjoen","year":"1985","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"13","key":"10.1002\/14651858.CD008684.pub3-BIB0056|cit56","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/BF01720833","article-title":"Effective and safe therapy with coenzyme Q10 for cardiomyopathy","volume":"66","author":"Langsjoen","year":"1988","journal-title":"Klinische Wochenschrift"},{"issue":"7","key":"10.1002\/14651858.CD008684.pub3-BIB0057|cit57","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/0002-9149(90)90824-K","article-title":"Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy","volume":"65","author":"Langsjoen","year":"1990","journal-title":"American Journal of Cardiology"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0058|cit58","doi-asserted-by":"crossref","first-page":"s165","DOI":"10.1016\/0098-2997(94)90026-4","article-title":"Usefulness of coenzyme Q10 in clinical cardiology: a long-term study","volume":"15 Suppl","author":"Langsjoen","year":"1994","journal-title":"Molecular Aspects of Medicine"},{"issue":"1-4","key":"10.1002\/14651858.CD008684.pub3-BIB0059|cit59","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/biof.5520320114","article-title":"Supplemental ubiquinol in patients with advanced congestive heart failure","volume":"32","author":"Langsjoen","year":"2008","journal-title":"Biofactors"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD008684.pub3-BIB0060|cit60","first-page":"82","article-title":"Changing of some markers of inflammation and remodeling in post-infarction patients with chronic heart failure after ubidecarenone treatment","volume":"20","author":"Leonova I","year":"2018","journal-title":"European Journal of Heart Failure"},{"issue":"3","key":"10.1002\/14651858.CD008684.pub3-BIB0061|cit61","first-page":"173","article-title":"Coenzyme Q10 in dilated cardiomyopathy","volume":"12","author":"Manzoli","year":"1990","journal-title":"International Journal of Tissue Reactions"},{"issue":"6","key":"10.1002\/14651858.CD008684.pub3-BIB0062|cit62","first-page":"923","article-title":"Noninvasive assessment of coenzyme Q10 in patients with chronic stable effort angina and moderate heart failure","volume":"41","author":"Mazzola","year":"1987","journal-title":"Current Therapeutic Research, Clinical and Experimental"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0063|cit63","first-page":"1027","article-title":"Prognostic importance of co-enzyme Q10 in heart failure and interaction with statin therapy in the controlled rosuvastatin Mmltinational trial in heart failure trial (CORONA)","volume":"30","author":"McMurray","year":"2009","journal-title":"European Heart Journal"},{"issue":"22","key":"10.1002\/14651858.CD008684.pub3-BIB0064|cit64","first-page":"Abstract 17490","article-title":"Coenzyme Q10 levels are associated with occurrence of cardiogenic\u00a0shock and in-hospital death in patients admitted to coronary care unit","volume":"128","author":"Miyazaki","year":"2013","journal-title":"Circulation"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0065|cit65","doi-asserted-by":"crossref","first-page":"s155","DOI":"10.1016\/0098-2997(94)90025-6","article-title":"Noninvasive evaluation of cardiac hemodynamics during exercise in patients with chronic heart failure: effects of short-term coenzyme Q10 treatment","volume":"15 Suppl","author":"Morisco","year":"1994","journal-title":"Molecular Aspects of Medicine"},{"issue":"8","key":"10.1002\/14651858.CD008684.pub3-BIB0066|cit66","first-page":"581","article-title":"Long-term coenzyme Q10 therapy: a major advance in the management of resistant myocardial failure","volume":"11","author":"Mortensen","year":"1985","journal-title":"Drugs under Experimental and Clinical Research"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0067|cit67","unstructured":"MitoQ supplementation and cardiovascular function in healthy men and women clinicaltrials.gov\/show\/nct03586414"},{"issue":"1","key":"10.1002\/14651858.CD008684.pub3-BIB0068|cit68","first-page":"27","article-title":"Therapeutic effects of coenzyme Q10 on dilated cardiomyopathy: assessment by 123I-BMIPP myocardial single photon emission computed tomography (SPECT): a multicenter trial in Osaka University Medical School Group","volume":"33","author":"Nishimura","year":"1996","journal-title":"Kaku Igaku (Japanese Journal of Nuclear Medicine)"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0069|cit69","first-page":"107","article-title":"CoQ10 treatment of patients with CHF and effects of BNP level","volume":"18","author":"Medvedev","year":"2016","journal-title":"European Journal of Heart Failure"},{"issue":"11","key":"10.1002\/14651858.CD008684.pub3-BIB0070|cit70","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1093\/oxfordjournals.eurheartj.a060096","article-title":"Ubiquinone (coenzyme Q10) in the long-term treatment of idiopathic dilated cardiomyopathy","volume":"13","author":"Permanetter","year":"1992","journal-title":"European Heart Journal"},{"issue":"5","key":"10.1002\/14651858.CD008684.pub3-BIB0071|cit71","first-page":"878","article-title":"Effect of coenzyme Q10 on left ventricular function in patients with dilative cardiomyopathy. A medium-term randomized double-blind study versus placebo","volume":"49","author":"Poggesi","year":"1991","journal-title":"Current Therapeutic Research, Clinical and Experimental"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0072|cit72","unstructured":"Atorvastatin\/coenzymeQ10 in congestive heart failure clinicaltrials.gov\/show\/nct01925937"},{"issue":"1","key":"10.1002\/14651858.CD008684.pub3-BIB0073|cit73","first-page":"1","article-title":"Combination of atorvastatin\/coenzyme Q10 as adjunctive treatment in congestive heart failure: a double-blind randomized placebo-controlled clinical trial","volume":"10","author":"Pourmoghaddas","year":"2014","journal-title":"Arya Atherosclerosis"},{"issue":"3","key":"10.1002\/14651858.CD008684.pub3-BIB0074|cit74","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1053\/j.ajkd.2016.08.041","article-title":"Effect of coenzyme Q10 on biomarkers of oxidative stress and cardiac function in hemodialysis\u00a0patients: the CoQ10 biomarker trial","volume":"69","author":"Rivera","year":"2017","journal-title":"American Journal of Kidney Diseases"},{"issue":"2-3","key":"10.1002\/14651858.CD008684.pub3-BIB0075|cit75","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1097\/00045391-199702000-00003","article-title":"The clinical and hemodynamic effects of coenzyme Q10 in congestive cardiomyopathy","volume":"4","author":"Sacher","year":"1997","journal-title":"American Journal of Therapeutics"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0076|cit76","first-page":"S30","article-title":"Comparative study of Ubiquinone (CoQ10) and Krill oil in dilated cardiomyopathy","volume":"46","author":"Saurabh","year":"2014","journal-title":"Indian Journal of Pharmacology"},{"issue":"7","key":"10.1002\/14651858.CD008684.pub3-BIB0077|cit77","first-page":"503","article-title":"Clinical studies with coenzyme Q10 in patients with congestive heart failure","volume":"10","author":"Schneeberger","year":"1984","journal-title":"Drugs Under Experimental and Clinical Research"},{"issue":"9","key":"10.1002\/14651858.CD008684.pub3-BIB0078|cit78","doi-asserted-by":"crossref","first-page":"745","DOI":"10.7326\/0003-4819-133-9-200011070-00020","article-title":"Coenzyme Q10 and congestive heart failure","volume":"133","author":"Sinatra","year":"2000","journal-title":"Annals of Internal Medicine"},{"issue":"10","key":"10.1002\/14651858.CD008684.pub3-BIB0079|cit79","doi-asserted-by":"crossref","first-page":"A26, A30","DOI":"10.1002\/clc.4960271017","article-title":"Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study (multiple letters)","volume":"27","author":"Sinatra","year":"2004","journal-title":"Clinical Cardiology"},{"issue":"3","key":"10.1002\/14651858.CD008684.pub3-BIB0080|cit80","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1111\/hdi.12022","article-title":"Coenzyme Q10 supplementation and diastolic heart functions in hemodialysis patients: a randomized double-blind placebo-controlled trial","volume":"17","author":"Turk","year":"2013","journal-title":"Hemodialysis International"},{"issue":"6","key":"10.1002\/14651858.CD008684.pub3-BIB0081|cit81","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1016\/S0735-1097(99)00064-9","article-title":"Lack of effect of coenzyme Q on left ventricular function in patients with congestive heart failure","volume":"33","author":"Watson","year":"1999","journal-title":"Journal of the American College of Cardiology"},{"issue":"21","key":"10.1002\/14651858.CD008684.pub3-BIB0082|cit82","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.1093\/eurheartj\/ehi442","article-title":"The effect of micronutrient supplementation on quality-of-life and left ventricular function in elderly patients with chronic heart failure","volume":"26","author":"Witte","year":"2005","journal-title":"European Heart Journal"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0083|cit83","unstructured":"Ubiquinol\u00a0treatment in patients with heart failure and preserved ejection fraction clinicaltrials.gov\/show\/nct02779634"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0084|cit84","unstructured":"CoQ10 and d-ribose in patients with diastolic heart failure clinicaltrials.gov\/show\/nct03133793"},{"issue":"1","key":"10.1002\/14651858.CD008684.pub3-BIB0085|cit85","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s12872-018-0796-2","article-title":"Study protocol, randomized controlled trial: reducing symptom burden in patients with heart failure with preserved ejection fraction using ubiquinol and\/or D-ribose","volume":"18","author":"Pierce J","year":"2018","journal-title":"BMC Cardiovascular Disorders"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0086|cit86","doi-asserted-by":"crossref","first-page":"s287","DOI":"10.1016\/0098-2997(94)90040-X","article-title":"Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure","volume":"15","author":"Baggio","year":"1994","journal-title":"Molecular Aspects of Medicine"},{"issue":"5","key":"10.1002\/14651858.CD008684.pub3-BIB0087|cit87","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1136\/hrt.65.5.245","article-title":"Oxygen free radicals and congestive heart failure","volume":"65","author":"Belch","year":"1991","journal-title":"British Heart Journal"},{"issue":"8","key":"10.1002\/14651858.CD008684.pub3-BIB0088|cit88","doi-asserted-by":"crossref","first-page":"703","DOI":"10.2165\/00002018-200629080-00007","article-title":"Effect of ezetimibe and\/or simvastatin on coenzyme Q10 levels in plasma: a randomised trial","volume":"29","author":"Berthold","year":"2006","journal-title":"Drug Safety"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0089|cit89","doi-asserted-by":"crossref","first-page":"S78","DOI":"10.1016\/j.mito.2007.03.003","article-title":"Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations","volume":"7S","author":"Bhagavan","year":"2007","journal-title":"Mitochondrion"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0090|cit90","volume-title":"Davidson's Principles and Practice of Medicine","author":"Boon","year":"2006"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0091|cit91","unstructured":"BMJ Clinical Evidence. EBM Tools: Glossary clinicalevidence.bmj.com\/ceweb\/resources\/glossary.jsp#Random_effects"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0092|cit92","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.freeradbiomed.2015.04.028","article-title":"Therapeutic targeting of oxidative stress with coenzyme Q10 counteracts exaggerated diabetic cardiomyopathy in a mouse model of diabetes with diminished PI3K (p110\u03b1) signaling","volume":"87","author":"De Blasio","year":"2015","journal-title":"Free Radical Biology and Medicine"},{"issue":"1","key":"10.1002\/14651858.CD008684.pub3-BIB0093|cit93","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/S0002-8703(96)90063-0","article-title":"Increased malondialdehyde in peripheral blood of patients with congestive heart failure","volume":"131","author":"Diaz-Velez","year":"1996","journal-title":"American Heart Journal"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0094|cit94","first-page":"829","volume-title":"Cardiology","author":"Drexler","year":"2004"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0095|cit95","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"issue":"10","key":"10.1002\/14651858.CD008684.pub3-BIB0096|cit96","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.4065\/76.10.1047","article-title":"Approach to patients with heart failure and normal ejection fraction","volume":"76","author":"Elesber","year":"2001","journal-title":"Mayo Clinic Proceedings"},{"issue":"22","key":"10.1002\/14651858.CD008684.pub3-BIB0097|cit97","doi-asserted-by":"crossref","first-page":"8931","DOI":"10.1073\/pnas.87.22.8931","article-title":"Lovastatin decreases coenzyme Q levels in humans","volume":"87","author":"Folkers","year":"1990","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"2","key":"10.1002\/14651858.CD008684.pub3-BIB0098|cit98","doi-asserted-by":"crossref","first-page":"268","DOI":"10.3945\/ajcn.112.040741","article-title":"Effect of coenzyme Q(10) supplementation on heart failure: a meta-analysis","volume":"97","author":"Fotino","year":"2013","journal-title":"American Journal of Clinical Nutrition"},{"issue":"8","key":"10.1002\/14651858.CD008684.pub3-BIB0099|cit99","doi-asserted-by":"crossref","first-page":"631","DOI":"10.7326\/0003-4819-137-8-200210150-00006","article-title":"Outcome of congestive heart failure in elderly persons: influence of left ventricular systolic function. The Cardiovascular Health Study","volume":"137","author":"Gottdiener","year":"2002","journal-title":"Annals of Internal Medicine"},{"issue":"7","key":"10.1002\/14651858.CD008684.pub3-BIB0100|cit100","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1002\/j.1552-4604.1990.tb01862.x","article-title":"Co-enzyme Q10: a new drug for cardiovascular disease","volume":"30","author":"Greenberg","year":"1990","journal-title":"Journal of Clinical Pharmacology"},{"issue":"14","key":"10.1002\/14651858.CD008684.pub3-BIB0101|cit101","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1080\/10408398.2018.1442316","article-title":"Coenzyme Q10: from bench to clinic in aging diseases, a translational review","volume":"59","author":"Gutierrez-Mariscal","year":"2019","journal-title":"Critical Reviews in Food Science and Nutrition"},{"issue":"13","key":"10.1002\/14651858.CD008684.pub3-BIB0102|cit102","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1093\/ajhp\/57.13.1221","article-title":"Potential interactions between alternative therapies and warfarin","volume":"57","author":"Heck","year":"2000","journal-title":"American Journal of Health-system Pharmacy"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0103|cit103","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0104|cit104","unstructured":"Higgins JPT Green S Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from training.cochrane.org\/handbook\/archive\/v5.1\/"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0105|cit105","doi-asserted-by":"crossref","unstructured":"Higgins JP Thomas J Chandler J Cumpston M Li T Page MJ Cochrane Handbook for Systematic Reviews of Interventions Version 6.0 (updated July 2019). Cochrane, 2019 Available from www.training.cochrane.org\/handbook","DOI":"10.1002\/9781119536604"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0106|cit106","doi-asserted-by":"crossref","first-page":"6A","DOI":"10.1016\/0735-1097(93)90455-A","article-title":"The epidemiology of heart failure: the Framingham study","volume":"22","author":"Ho","year":"1993","journal-title":"Journal of the American College of Cardiology"},{"issue":"1","key":"10.1002\/14651858.CD008684.pub3-BIB0107|cit107","first-page":"157","article-title":"Bioenergetics in clinical medicine XV. Inhibition of coenzyme Q10 enzymes by clinically used adrenergic blockers of beta-receptors","volume":"17","author":"Kishi","year":"1977","journal-title":"Research Communications in Chemical Pathology and Pharmacology"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0108|cit108","unstructured":"Lefebvre C Manheimer E Glanville J Chapter 6: Searching for studies. In: Higgins JP, Green S, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from training.cochrane.org\/handbook\/archive\/v5.1\/"},{"issue":"15","key":"10.1002\/14651858.CD008684.pub3-BIB0109|cit109","doi-asserted-by":"publisher","first-page":"1","DOI":"10.21037\/amj.2020.03.03","article-title":"Global epidemiology and future trends of heart failure","volume":"5","author":"Lippi","year":"2020","journal-title":"AME Medical Journal"},{"issue":"6","key":"10.1002\/14651858.CD008684.pub3-BIB0110|cit110","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008684.pub2","article-title":"Coenzyme Q10 for heart failure","author":"Madmani","year":"2014","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"18","key":"10.1002\/14651858.CD008684.pub3-BIB0111|cit111","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/0002-9149(90)90985-A","article-title":"Evidence for enhanced free radical activity in chronic congestive heart failure secondary to coronary artery disease","volume":"65","author":"McMurray","year":"1990","journal-title":"American Journal of Cardiology"},{"issue":"11","key":"10.1002\/14651858.CD008684.pub3-BIB0112|cit112","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1093\/eurheartj\/14.11.1493","article-title":"Evidence of oxidative stress in chronic heart failure in humans","volume":"14","author":"McMurray","year":"1993","journal-title":"European Heart Journal"},{"issue":"1","key":"10.1002\/14651858.CD008684.pub3-BIB0113|cit113","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/mutage\/geg036","article-title":"Evaluation of cytogenetic and DNA damage in mitochondrial disease patients: effects of coenzyme Q10 therapy","volume":"19","author":"Migliore","year":"2004","journal-title":"Mutagenesis"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0114|cit114","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S0140-6736(98)01085-X","article-title":"Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analysis","volume":"352","author":"Moher","year":"1998","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0115|cit115","doi-asserted-by":"crossref","first-page":"B2535","DOI":"10.1136\/bmj.b2535","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"339","author":"Moher","year":"2009","journal-title":"BMJ"},{"issue":"18","key":"10.1002\/14651858.CD008684.pub3-BIB0116|cit116","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1016\/j.jacc.2008.07.044","article-title":"Coenzyme Q10: an independent predictor of mortality in chronic heart failure","volume":"52","author":"Molyneux","year":"2008","journal-title":"Journal of the American College of Cardiology"},{"issue":"7","key":"10.1002\/14651858.CD008684.pub3-BIB0117|cit117","first-page":"497","article-title":"Deficiency of coenzyme Q10 in myocardial failure","volume":"X","author":"Mortensen","year":"1984","journal-title":"Drugs under Experimental and Clinical Research"},{"issue":"3","key":"10.1002\/14651858.CD008684.pub3-BIB0118|cit118","first-page":"155","article-title":"Coenzyme Q10: clinical benefits with biochemical correlates suggesting a scientific breakthrough in the management of chronic heart failure","volume":"12","author":"Mortensen","year":"1990","journal-title":"International Journal of Tissue Reactions"},{"issue":"8 Suppl","key":"10.1002\/14651858.CD008684.pub3-BIB0119|cit119","first-page":"S116","article-title":"Perspectives on therapy of cardiovascular diseases with coenzyme Q10 (ubiquinone)","volume":"71","author":"Mortensen","year":"1993","journal-title":"Clinical Investigator"},{"issue":"Suppl","key":"10.1002\/14651858.CD008684.pub3-BIB0120|cit120","doi-asserted-by":"crossref","first-page":"S137","DOI":"10.1016\/S0098-2997(97)00014-9","article-title":"Dose-related decrease of serum coenzyme Q10 during treatment with HMG-CoA reductase inhibitors","volume":"18","author":"Mortensen","year":"1997","journal-title":"Molecular Aspects of Medicine"},{"issue":"4","key":"10.1002\/14651858.CD008684.pub3-BIB0121|cit121","doi-asserted-by":"crossref","first-page":"257","DOI":"10.7150\/ijbs.3.257","article-title":"Enrichment of coenzyme Q10 in plasma and blood cells: defence against oxidative damage","volume":"3","author":"Niklowitz","year":"2007","journal-title":"International Journal of Biological Sciences"},{"issue":"1","key":"10.1002\/14651858.CD008684.pub3-BIB0122|cit122","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0002-8703(98)70351-5","article-title":"Oxidative stress is related to exercise intolerance in patients with heart failure","volume":"135","author":"Nishiyama","year":"1998","journal-title":"American Heart Journal"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0123|cit123","volume-title":"Diseases of the Heart and Blood Vessels: Nomenclature and Criteria for Diagnosis","author":"Criteria Committee","year":"1964"},{"issue":"27","key":"10.1002\/14651858.CD008684.pub3-BIB0124|cit124","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1093\/eurheartj\/ehw128","article-title":"2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure of the European Society of Cardiology (ESC) developed with the special contribution of the Heart Failure Association (HFA) of the ESC","volume":"37","author":"Ponikowski","year":"2016","journal-title":"European Heart Journal"},{"issue":"3","key":"10.1002\/14651858.CD008684.pub3-BIB0125|cit125","doi-asserted-by":"crossref","first-page":"185","DOI":"10.14797\/mdcj-15-3-185","article-title":"Coenzyme Q10","volume":"15","author":"Raizner","year":"2019","journal-title":"Methodist DeBakey Cardiovascular Journal"},{"issue":"4","key":"10.1002\/14651858.CD008684.pub3-BIB0126|cit126","first-page":"209","article-title":"Function of coenzyme Q in the cell: some biochemical and physiological properties","volume":"44","author":"Rauchova","year":"1995","journal-title":"Physiological Research"},{"issue":"19","key":"10.1002\/14651858.CD008684.pub3-BIB0127|cit127","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1056\/NEJMcp1511175","article-title":"Heart failure with preserved ejection fraction","volume":"375","author":"Redfield","year":"2016","journal-title":"New England Journal of Medicine"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0128|cit128","unstructured":"Review Manager 5 (RevMan 5) The Cochrane Collaboration 2020"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0129|cit129","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1161\/01.CIR.93.5.841","article-title":"Report of the 1995 Word Health Organization\/International Society and Federation of Cardiology Task Force on the Definition and classification of cardiomyopathies","volume":"93","author":"Richardson","year":"1996","journal-title":"Circulation"},{"issue":"2","key":"10.1002\/14651858.CD008684.pub3-BIB0130|cit130","first-page":"163","article-title":"Epidemiology of heart failure","volume":"57","author":"Rodriguez-Artalejo","year":"2004","journal-title":"Revista Espanola de Cardiologia"},{"issue":"1-4","key":"10.1002\/14651858.CD008684.pub3-BIB0131|cit131","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1002\/biof.5520180211","article-title":"Systematic review of effect of coenzyme Q10 in physical exercise, hypertension and heart failure","volume":"18","author":"Rosenfeldt","year":"2003","journal-title":"BioFactors (Oxford, England)"},{"issue":"6","key":"10.1002\/14651858.CD008684.pub3-BIB0132|cit132","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.cardfail.2006.03.007","article-title":"The impact of coenzyme Q10 on systolic function in patients with chronic heart failure","volume":"12","author":"Sander","year":"2006","journal-title":"Journal of Cardiac Failure"},{"issue":"1","key":"10.1002\/14651858.CD008684.pub3-BIB0133|cit133","doi-asserted-by":"crossref","first-page":"7","DOI":"10.15420\/cfr.2016:25:2","article-title":"Global public health burden of heart failure","volume":"3","author":"Savarese","year":"2017","journal-title":"Cardiac Failure Review"},{"issue":"2","key":"10.1002\/14651858.CD008684.pub3-BIB0134|cit134","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/sj.jhh.1000778","article-title":"Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease","volume":"13","author":"Singh","year":"1999","journal-title":"Journal of Human Hypertension"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0135|cit135","doi-asserted-by":"crossref","first-page":"S159","DOI":"10.1016\/S0098-2997(97)00042-3","article-title":"Treatment of congestive heart failure with coenzyme Q10 illuminated by meta-analyses of clinical trials","volume":"18 Suppl","author":"Soja","year":"1997","journal-title":"Molecular Aspects of Medicine"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0136|cit136","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1111\/j.1749-6632.1972.tb27851.x","article-title":"Vitamin E and free radical peroxidation of lipids","volume":"203","author":"Tappel","year":"1972","journal-title":"Annals of The New York Academy of Sciences"},{"key":"10.1002\/14651858.CD008684.pub3-BIB0137|cit137","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1016\/0002-8703(91)90072-P","article-title":"An overview of contemporary etiologies of congestive heart failure","volume":"121","author":"Teerlink","year":"1991","journal-title":"American Heart Journal"},{"issue":"5","key":"10.1002\/14651858.CD008684.pub3-BIB0138|cit138","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.jnutbio.2011.01.011","article-title":"A novel mechanism of coenzyme Q10 protects against human endothelial cells from oxidative stress-induced injury by modulating NO-related pathways","volume":"23","author":"Tsai","year":"2012","journal-title":"Journal of Nutritional Biochemistry"},{"issue":"6","key":"10.1002\/14651858.CD008684.pub3-BIB0139|cit139","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/S0735-1097(02)01721-7","article-title":"Plasma oxidized low-density lipoprotein as a prognostic predictor in patients with chronic congestive heart failure","volume":"39","author":"Tsutsui","year":"2002","journal-title":"Journal of the American College of Cardiology"},{"issue":"9","key":"10.1002\/14651858.CD008684.pub3-BIB0140|cit140","doi-asserted-by":"publisher","first-page":"e139","DOI":"10.1161\/CIR.0000000000000757","article-title":"Heart disease and stroke statistics 2020 update: a report from the American Heart Association","volume":"141","author":"Virani","year":"2020","journal-title":"Circulation"},{"issue":"6","key":"10.1002\/14651858.CD008684.pub3-BIB0141|cit141","doi-asserted-by":"publisher","first-page":"e137","DOI":"10.1161\/CIR.0000000000000509","article-title":"2017 ACC\/AHA\/HFSA focused update of the 2013 ACCF\/AHA guideline for the management of heart failure: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America","volume":"136","author":"Yancy","year":"2017","journal-title":"Circulation"},{"issue":"6","key":"10.1002\/14651858.CD008684.pub3-BIB0142|cit142","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008684.pub2","article-title":"Coenzyme Q10 for heart failure","author":"Al Saadi","year":"2014","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T21:03:57Z","timestamp":1761253437000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD008684.pub3"}},"subtitle":[],"editor":[{"name":"Cochrane Heart Group","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,2,3]]},"references-count":142,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,2]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd008684.pub3","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,3]]}}}