{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T22:53:46Z","timestamp":1767135226934,"version":"build-2238731810"},"update-to":[{"DOI":"10.1002\/14651858.cd008951","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2012,1,18]],"date-time":"2012-01-18T00:00:00Z","timestamp":1326844800000}}],"reference-count":125,"publisher":"Wiley","issue":"2","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd008951.pub2","type":"journal-article","created":{"date-parts":[[2012,1,18]],"date-time":"2012-01-18T17:29:20Z","timestamp":1326907760000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Pain management for inflammatory arthritis (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and other spondyloarthritis) and gastrointestinal or liver comorbidity"],"prefix":"10.1002","volume":"2012","author":[{"given":"Helga","family":"Radner","sequence":"first","affiliation":[{"name":"Medical University Vienna; Division of Rheumatology, Department of Internal Medicine 3; Waehringer Guertel 18-20 Vienna Austria 1090"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofia","family":"Ramiro","sequence":"additional","affiliation":[{"name":"Hospital Garcia de Orta; Department of Rheumatology; Almada Portugal"},{"name":"Academic Medical Centre; Department of Clinical Immunology & Rheumatology; Amsterdam Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachelle","family":"Buchbinder","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University; Monash Department of Clinical Epidemiology at Cabrini Hospital; Suite 41, Cabrini Medical Centre 183 Wattletree Road Malvern Victoria Australia 3144"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert BM","family":"Landew\u00e9","sequence":"additional","affiliation":[{"name":"Academic Medical Centre; Department of Clinical Immunology & Rheumatology; Amsterdam Netherlands"},{"name":"Atrium Medical Centre; Department of Rheumatology; P. Debyeplein 15 Heerlen Limburg Netherlands 6201AZ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D\u00e9sir\u00e9e","family":"van der Heijde","sequence":"additional","affiliation":[{"name":"Leiden University Medical Center; Department of Rheumatology; PO Box 9600 Leiden Netherlands 2300 RC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Aletaha","sequence":"additional","affiliation":[{"name":"Medical University Vienna; Division of Rheumatology, Department of Internal Medicine 3; Waehringer Guertel 18-20 Vienna Austria 1090"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,1,18]]},"reference":[{"key":"10.1002\/14651858.CD008951.pub2-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1002\/j.1552-4604.1975.tb01468.x","article-title":"An open trial of naproxen in rheumatoid arthritis patients with significant esophageal, gastric, and duodenal lesions","volume":"15","author":"Roth","year":"1975","journal-title":"Journal of Clinical Pharmacology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0002|cit2","first-page":"69","article-title":"Experiences with 800 mg ibuprofen retard in ambulatory patients with activated osteoarthrosis and extra-articular rheumatic manifestations","volume":"50","author":"Adam","year":"1991","journal-title":"Zeitschrift f\u00fcr Rheumatologie"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0003|cit3","first-page":"99","article-title":"Multicentre trial of piroxicam in ambulant rheumatology","volume":"6","author":"Alvart","year":"1983","journal-title":"European Journal of Rheumatology and Inflammation"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1080\/03009742.1979.12088616","article-title":"Fenbufen and Indomethacin in the treatment of rheumatoid arthritis","volume":"23","author":"Ammitzboll","year":"1979","journal-title":"Scandinavian Journal of Rheumatology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0005|cit5","first-page":"15","article-title":"A double blind randomised controlled trial of droxicam versus indomehtacin in rheumatoid arthritis","volume":"11","author":"Andrada","year":"1991","journal-title":"European Journal of Rheumatology and Inflammation"},{"issue":"5","key":"10.1002\/14651858.CD008951.pub2-BIB0006|cit6","first-page":"228","article-title":"Proglumetacin versus indomethacin in rheumatoid arthritis: A double-blind multicenter study","volume":"11","author":"Appelboom","year":"1994","journal-title":"Advances in Therapy"},{"issue":"7-8","key":"10.1002\/14651858.CD008951.pub2-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1345\/aph.10382","article-title":"Upper gastroduodenal ulceration in arthritis patients treated with celecoxib","volume":"35","author":"Ashcroft","year":"2001","journal-title":"The Annals of Pharmacotherapy"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0008|cit8","first-page":"6","article-title":"A comparison of the efficacy and tolerability of lornoxicam and indomethacin in ankylosing spondylithis","volume":"12","author":"Bernstein","year":"1992","journal-title":"European Journal of Rheumatology and Inflammation"},{"issue":"21","key":"10.1002\/14651858.CD008951.pub2-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1056\/NEJM200011233432103","article-title":"Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis","volume":"343","author":"Bombardier","year":"2000","journal-title":"The New England Journal of Medicine"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0010|cit10","first-page":"309","article-title":"A comparison of flurbiprofen with naproxen in ankylosing spondylitis","volume":"92","author":"Burry","year":"1980","journal-title":"The New Zealand Medical Journal"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0011|cit11","first-page":"1","article-title":"A long-term study of flurbiprofen in rheumatological disorders: I Rheumatoid arthritis","volume":"14","author":"Busson","year":"1986","journal-title":"Journal of International Medical Research"},{"issue":"2","key":"10.1002\/14651858.CD008951.pub2-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1177\/030006057700502S12","article-title":"Butacote: A six-year follow-up of patients with gastric intolerance to other medications","volume":"5","author":"Cardoe","year":"1977","journal-title":"Journal of International Medical Research"},{"issue":"3","key":"10.1002\/14651858.CD008951.pub2-BIB0013|cit13","first-page":"133","article-title":"Lornoxicam versus diclofenac in rheumtoid arthritis: A double-blind multicenter study","volume":"11","author":"Caruso","year":"1994","journal-title":"Advances in Therapy"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1592\/phco.29.12.1397","article-title":"Risk of upper gastrointestinal complications associated with cyclooxygenase-2-selective and nonselective nonsteroidal antiinflammatory drugs","volume":"29","author":"Castellsagugue","year":"2009","journal-title":"Pharmacotherapy"},{"issue":"26","key":"10.1002\/14651858.CD008951.pub2-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1056\/NEJMoa021907","article-title":"Celecoxib versus diclofenac and omeprazol in reducing the risk of recurrent ulcer bleeding in patients with arthritis","volume":"347","author":"Chan","year":"2002","journal-title":"The New England Journal of Medicine"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1053\/j.gastro.2004.07.010","article-title":"Celecoxib versus diclofenac plus omeprazole in high risk arthritis patients: Results of a randomized double-blind trial","volume":"127","author":"Chan","year":"2004","journal-title":"Gastroenterology"},{"issue":"9736","key":"10.1002\/14651858.CD008951.pub2-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0140-6736(10)60673-3","article-title":"Celecoxib versus omeprazole and diclofenac in patients with osteoarthritis and rheumatoid arthritis (CONDOR): a randomised trial","volume":"376","author":"Chan","year":"2010","journal-title":"Lancet"},{"issue":"4","key":"10.1002\/14651858.CD008951.pub2-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/S0149-2918(00)89009-8","article-title":"Efficacy and tolerability of meloxicam in an observational, controlled cohort study in patients with rheumatic disease","volume":"22","author":"Degner","year":"2000","journal-title":"Clinical Therapeutics"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3109\/03009749209095096","article-title":"The safety of arthrotec in patients with rheumatoid arthritis or osteoarthritis: An assessment of the upper gastrointestinal tract by endoscopy","volume":"96","author":"Melo Gomes","year":"1992","journal-title":"Scandinavian Journal of Rheumatology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1517\/14656566.6.2.347","article-title":"The safety of lumiracoxib when used in the treatment of arthritis","volume":"6","author":"Doggrell","year":"2005","journal-title":"Expert Opinion on Pharmacotherapy"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1111\/j.1365-2036.2005.02383.x","article-title":"Meta-analysis: upper gastrointestinal tolerability of valdecoxib, a cyclooxygenase-2-specific inhibitor, compared with nonspecific nonsteroidal anti-inflammatory drugs among patients with osteoarthritis and rheumatoid arthritis","volume":"21","author":"EIsen","year":"2005","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/j.1572-0241.2006.00384.x","article-title":"The gastrointestinal safety and effect on disease activity of etoricoxib, a selective cox-2 inhibitor in inflammatory bowel disease","volume":"101","author":"Miedany","year":"2006","journal-title":"American Journal of Gastroenterology"},{"issue":"1","key":"10.1002\/14651858.CD008951.pub2-BIB0023|cit23","first-page":"52","article-title":"Association of esophagitis and esophageal strictures with diseases treated with nonsteroidal anti-inflammatory drugs","volume":"92","author":"El-Serag","year":"1997","journal-title":"The American Journal of Gastroenerology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0024|cit24","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.1016\/S0140-6736(99)02332-6","article-title":"Celecoxib versus diclofenac in long-term management of rheumatoid arthritis: randomised double-blind comparison","volume":"354","author":"Emery","year":"1999","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/0002-9343(93)90391-2","article-title":"Safety experience with nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis","volume":"95","author":"Eversmeyer","year":"1993","journal-title":"The American Journal of Medicine"},{"issue":"6","key":"10.1002\/14651858.CD008951.pub2-BIB0026|cit26","first-page":"1058","article-title":"A double-blind, crossover, multicenter study of piroxicam and naproxen in rheumatoid arthritis","volume":"66","author":"Fenton","year":"1988","journal-title":"Current Therapeutic Research"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0027|cit27","first-page":"93","article-title":"Clinical evaluation of ketoprofen in rheumatoid arthritis","volume":"14 Suppl","author":"Fossgreen","year":"1976","journal-title":"Scandinavian Journal of Rheumatology"},{"issue":"2","key":"10.1002\/14651858.CD008951.pub2-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1007\/BF02032359","article-title":"A comparison of diflunisal and phenylbutazone in the treatment of ankylosing spondylitis","volume":"5","author":"Franssen","year":"1986","journal-title":"Clinical Rheumatology"},{"issue":"3","key":"10.1002\/14651858.CD008951.pub2-BIB0029|cit29","first-page":"436","article-title":"Dose response and safety study of meloxicam up to 22.5mg daily in rheumatoid arthritis: A 12 week mulitcenter, double blind, dose response study versus placebo and diclofenac","volume":"29","author":"Furst","year":"2002","journal-title":"The Journal of Rheumatology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0030|cit30","first-page":"25","article-title":"Arthrotec: A therapeutic option in the management of arthritis","volume":"13","author":"Geis","year":"1993","journal-title":"European Journal of Rheumatology and Inflammation"},{"issue":"7","key":"10.1002\/14651858.CD008951.pub2-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1111\/j.1572-0241.2000.02194.x","article-title":"Reduced risk of upper gastrointestinal ulcer complications with celecoxib, a novel COX-2-inhibitor","volume":"95","author":"Goldstein","year":"2000","journal-title":"The American Journal of Gastroenterology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1111\/j.1365-2036.2004.02118.x","article-title":"Reduced incidence of upper gastrointestinal ulcer complications with the COX-2 selective inhibitor, valdecoxib","volume":"20","author":"Goldstein","year":"2004","journal-title":"Alimentary Pharmacology and Therapy"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0033|cit33","first-page":"20","article-title":"Once-daily or twice daily administration of naproxen in patients with rheumatoid arthritis","volume":"13","author":"Graziano","year":"1991","journal-title":"Clinical Therapeutics"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1177\/003693307702200107","article-title":"Therapeutic uses of azapropazone","volume":"22","author":"Grennan","year":"1977","journal-title":"Scottish Medical Journal"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0035|cit35","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1001\/archinte.160.14.2093","article-title":"Association between nonsteroidal anti-inflammatory drugs and upper gastrointestinal tract bleeding\/perforation","volume":"160","author":"Hern\u00e1ndez-Diaz","year":"2010","journal-title":"Archives of Internal Medicine"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1177\/030006057800600407","article-title":"A double-blind crossover evaluation of ketoprofen and placebo in rheumatoid arthritis with assessment of long-term tolerance","volume":"6","author":"Howard","year":"1978","journal-title":"The Journal of International Medical Research"},{"issue":"4","key":"10.1002\/14651858.CD008951.pub2-BIB0037|cit37","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/BF02230353","article-title":"Aceclofenac in rheumatoid arthritis: a useful and novel anti-Inflammatory","volume":"15","author":"Hunter","year":"1996","journal-title":"Clinical Rheumatology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0038|cit38","first-page":"4","article-title":"A clinical comparison of two leading non-steroidal anti-inflammatory drugs","volume":"11","author":"Huskisson","year":"1991","journal-title":"European Journal of Rheumatology and Inflammation"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1093\/rheumatology\/35.suppl_1.29","article-title":"A long-term study to evaluate the safety and efficacy of meloxicam therapy in patients with rheumatoid arthritis","volume":"35 Suppl 1","author":"Huskisson","year":"1996","journal-title":"British Journal of Rheumatology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0040|cit40","first-page":"809","article-title":"Gastrointestinal safety of amtolmetin guacyl in comparison with celecoxib in patients with rheumatoid arthritis","volume":"23","author":"Jajic","year":"2005","journal-title":"Clinical and Experimental Rheumatology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0041|cit41","first-page":"170","article-title":"Relapses of NSAID-induced ulcers in rheumatologic patients who continue treatment with NSAIDs (meeting abstract)","volume":"67 Suppl II","author":"Karateev","year":"2008","journal-title":"Annals of Rheumatic Disease"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0042|cit42","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/BF02663742","article-title":"Open study on the efficacy and safety of long-term use of surgam-sr (sustained-release form of tiaprofenic acid) in rheumatoid arthritis patients","volume":"2","author":"Kean","year":"1993","journal-title":"Inflammopharmacololgy"},{"issue":"3","key":"10.1002\/14651858.CD008951.pub2-BIB0043|cit43","first-page":"148","article-title":"A double-blind crossover compariosn of ketoprofen and indomethacin in ankylosing spondylitis","volume":"8","author":"Kennedy","year":"1991","journal-title":"Advances in Therapy"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1080\/00325481.1974.11713882","article-title":"Salicylate hepatotoxicity","volume":"56","author":"Koppes","year":"1974","journal-title":"Postgraduate Medicine"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0045|cit45","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1136\/ard.2007.082388","article-title":"Gastrointestinal tolerability of etoricoxib in rheumatoid arthritis patients: results of the etoricoxib vs. diclofenac sodium gastrointestinal tolerability and effectiveness trial (EDGE II)","volume":"67","author":"Krueger","year":"2008","journal-title":"Annals of Rheumatic Diseases"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0046|cit46","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1053\/gast.2002.36013","article-title":"Stratifying the risk of NSAID-related upper gastrointestinal clinical events: Results of a double-blind outcomes study in patients with rheumatoid arthritis","volume":"123","author":"Laine","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0047|cit47","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1111\/j.1365-2036.2006.03043.x","article-title":"Systematic review: the lower gastrointestinal adverse effects of non-steroidal anti-inflammatory drugs","volume":"24","author":"Laine","year":"2006","journal-title":"Alimentary Pharmacology and Therapy"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/S0140-6736(07)60234-7","article-title":"Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Mulinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison","volume":"369","author":"Laine","year":"2007","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0049|cit49","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1053\/j.gastro.2008.07.067","article-title":"Lower gastrointestinal events in a double-blind trial of the cyclo-oxygenase-2-selective inhibitor etoricoxib and the traditional nonsteroidal anti-inflammatory crug diclofenac","volume":"135","author":"Laine","year":"2008","journal-title":"Gastroenterology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0050|cit50","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.dld.2007.04.002","article-title":"COXIBs and non-selective NSAIDs in the gastroenterological setting: what should patients and physicians do?","volume":"39","author":"Lazzaroni","year":"2007","journal-title":"Digestive and Liver Disease"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0051|cit51","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1007\/BF02330602","article-title":"A six-month follow-up study of a slow-release indomehtacin tablet in rheumatic diseases","volume":"6","author":"Lehtinen","year":"1987","journal-title":"Clinical Rheumatology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0052|cit52","first-page":"21","article-title":"Clinical efficacy and safety of naprelan versus naprosyn in the treatment of rheumatoid arthritis","volume":"25","author":"Lisse","year":"1996","journal-title":"American Journal of Orthopedics"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0053|cit53","first-page":"99","article-title":"A double blind cross-over evaluation of ketorprofen and aspirin in rheumatoid arthritis","volume":"14 Suppl","author":"Lussier","year":"1976","journal-title":"Scandinavian Journal of Rheumatology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0054|cit54","first-page":"16","article-title":"Asymptomatic and symptomatic gastroduodenal patients affected by rheumatic disease treated with non-steroidal anti-inflammatory drugs","volume":"31","author":"Magaro","year":"1989","journal-title":"Panminerva Medica"},{"issue":"2","key":"10.1002\/14651858.CD008951.pub2-BIB0055|cit55","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1136\/gut.28.2.226","article-title":"Randomised study of the influence of non-steroidal anti-inflammatory drugs on the treatment of peptic ulcer in patients with rheumatic disease","volume":"28","author":"Manniche","year":"1987","journal-title":"Gut"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0056|cit56","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3109\/03009747609095639","article-title":"A long-term study of benorylate in patients with rheumatoid arthritis","volume":"13","author":"Muller-Fassbender","year":"1976","journal-title":"Scandinavian Journal of Rheumatology"},{"issue":"3","key":"10.1002\/14651858.CD008951.pub2-BIB0057|cit57","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1185\/03007990802714382","article-title":"Pooled analysis of GI tolerability of 21 randomized controlled trials of celecoxib and nonselective NSAIDs","volume":"25","author":"Niculescu","year":"2009","journal-title":"Current Medical Research and Opinions"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0058|cit58","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1365-2036.2006.02745.x","article-title":"Systematic review: coxibs, non-steroidal anti-inflammatory drugs or non cyclo-oxygenase inhibitors in gastroenterological high risk patients","volume":"23","author":"Nielsen","year":"2006","journal-title":"Alimentary Pharmacology and Therapy"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0059|cit59","first-page":"105","article-title":"Ketoprofen in the treatment of rheumatoid arthritis: double blind cross-over placebo comparison","volume":"14 Suppl","author":"O'Brien","year":"1976","journal-title":"Scandinavian Journal of Rheumatology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0060|cit60","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/BF02229644","article-title":"Comparative study of the efficacy and safety of aceclofenac and tenoxicam in rheumatoid arthritis","volume":"15","author":"Perez-Ruiz","year":"1996","journal-title":"Clinical Rheumatology"},{"issue":"12","key":"10.1002\/14651858.CD008951.pub2-BIB0061|cit61","first-page":"1037","article-title":"Therapeutic efficacy and gastric tolerance of ibuprofen at 1600-2400 mg dosage in rheumatoid arthritis","volume":"41","author":"Porkodi","year":"1987","journal-title":"The British Journal of Clinical Practice"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0062|cit62","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1093\/rheumatology\/kel428","article-title":"Risk and benefits of COX-2-inhibitors vs non-selective NSAIDs: does their cardiovascular risk exceed their gastrointestinal benefit? A retrospective cohort study","volume":"46","author":"Rahme","year":"2007","journal-title":"Rheumatology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1046\/j.1365-2036.2003.01596.x","article-title":"An open-label trial of the selective cyclo-oxygenase 2 inhibitor rofecoxib in inflammatory bowel disease associated peripheral arthritis and arthralgia","volume":"17","author":"Reinisch","year":"2003","journal-title":"Alimentary Pharmacology and Therapy"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0064|cit64","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.phrs.2009.03.021","article-title":"Efficacy and safety of piroxicam revisited: a global meta-analysis of randomised control trials","volume":"60","author":"Richy","year":"2009","journal-title":"Pharmacological Research"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0065|cit65","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1185\/03007997409111740","article-title":"A short-term double blind controlled trial of prenazone (DA2370) in rheumatoid arthritis","volume":"2","author":"Rooney","year":"1974","journal-title":"Current Medical Research and Opinion"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0066|cit66","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S1542-3565(04)00777-3","article-title":"Nonsteroidal anti-inflammatory drugs and hepatic toxicity: a systematic review of randomized controlled trials in arthritis patients","volume":"3","author":"Rostom","year":"2005","journal-title":"Clinical Gastroenterology and Hepatology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0067|cit67","first-page":"43","article-title":"Longterm fenoprofen therapy in patients with rheumtoid arthritis","volume":"2","author":"Roth","year":"1976","journal-title":"Journal of Rheumatology"},{"issue":"3","key":"10.1002\/14651858.CD008951.pub2-BIB0068|cit68","doi-asserted-by":"crossref","first-page":"171","DOI":"10.2165\/00044011-199509030-00007","article-title":"Endoscopic evaluation of the long term effects of diclofenac sodium and naproxen in elderly patients with arthritis","volume":"9","author":"Roth","year":"1995","journal-title":"Clinical Drug Investigation"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0069|cit69","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1002\/j.1552-4604.1976.tb02416.x","article-title":"Anti-inflammatory drugs and gastrointestinal bleeding: a comparison of aspirin and ibuprofen","volume":"16","author":"Schmid","year":"1976","journal-title":"Journal of Clinical Pharmacology"},{"issue":"5","key":"10.1002\/14651858.CD008951.pub2-BIB0070|cit70","first-page":"349","article-title":"Indomethacin in rheumatoid arthritis","volume":"25","author":"Seideman","year":"1988","journal-title":"Clinical Trials Journal"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD008951.pub2-BIB0071|cit71","first-page":"65","article-title":"Acetaminophen in patients with rheumatic disease with concomitant liver diseases: pharmacokinetics, effectiveness and tolerance","volume":"46","author":"Seissiger","year":"1987","journal-title":"Zeitschrift f\u00fcr Rheumatologie"},{"issue":"Suppl.1","key":"10.1002\/14651858.CD008951.pub2-BIB0072|cit72","first-page":"40","article-title":"Stomach tolerance of nonsteroidal antirheumatic drugs: comparative endoscopic study","volume":"46","author":"Simon","year":"1987","journal-title":"Zeitschrift f\u00fcr Rheumatologie"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0073|cit73","first-page":"328","article-title":"A large multicentre, parallel group, double-blind study comparing tenoxicam and piroxicam in the treatment of osteoarthritis and rheumatoid arthritis","volume":"43","author":"Simpson","year":"1989","journal-title":"British Journal of Clinical Practice"},{"issue":"14","key":"10.1002\/14651858.CD008951.pub2-BIB0074|cit74","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1001\/archinte.1996.00440130066007","article-title":"Gastrointestinal tract complications of nonsteroidal anti-inflammatory drug treatment in rheumatoid arthritis: a prospective observational cohort study","volume":"156","author":"Singh","year":"1996","journal-title":"Archives of Internal Medicine"},{"issue":"8","key":"10.1002\/14651858.CD008951.pub2-BIB0075|cit75","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1185\/03007990903018279","article-title":"The hepatic safety and tolerability of the cyclooxgenase-2 selective NSAID celecoxib: pooled analysis of 41 randomized controlled trials","volume":"25","author":"Soni","year":"2009","journal-title":"Current Medical Research and Opinion"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0076|cit76","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3109\/03009747609165453","article-title":"Comparative clinical trial with a new substance, diftalone, versus indomethacin in 30 patients with rheumatoid arthritis","volume":"5","author":"Tausch","year":"1976","journal-title":"Scandanavian Journal of Rheumatology"},{"issue":"6","key":"10.1002\/14651858.CD008951.pub2-BIB0077|cit77","first-page":"1129","article-title":"Double-blind comparative multicenter study of the efficacy and safety of a slow release tablet of 200 mg ketoprofen once daily and a 50mg ketoprofen capsule four times daily","volume":"40","author":"Teule","year":"1986","journal-title":"Current Therapeutic Research"},{"issue":"3","key":"10.1002\/14651858.CD008951.pub2-BIB0078|cit78","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0049-0172(88)90042-X","article-title":"Hepatic and renal tolerability of long-term naproxen treatment in patients with rheumatoid arthritis","volume":"17","author":"Turner","year":"1988","journal-title":"Seminars in Arthritis and Rheumatism"},{"issue":"10","key":"10.1002\/14651858.CD008951.pub2-BIB0079|cit79","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1185\/030079904X3078","article-title":"The upper gastrointestinal safety of rofecoxib versus NSAIDs: an updated combined analysis","volume":"20","author":"Watson","year":"2004","journal-title":"Current Medical Research and Opinion"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0080|cit80","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1093\/rheumatology\/XVII.suppl.78","article-title":"A comparison of ketoprofen and naproxen in rheumatoid arthritis","volume":"Suppl","author":"Wollheim","year":"1978","journal-title":"Rheumatology and Rehabilitation"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0081|cit81","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s00535-008-2260-z","article-title":"Cyclooxygenase-2-inhibitors in patients with high gastrointestinal risk: are we there yet?","volume":"44 Suppl XIX","author":"Wong","year":"2009","journal-title":"Journal of Gastroenterololgy"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0082|cit82","first-page":"77","article-title":"Ketorprofen in rheumatoid arthritis: its tolerance and therapeutic effect","volume":"14 Suppl","author":"Zutshi","year":"1976","journal-title":"Scandinavian Journal of Rheumatology"},{"issue":"14","key":"10.1002\/14651858.CD008951.pub2-BIB0083|cit83","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.2174\/1381612053764904","article-title":"Gastrointestinal effects of selective and non-selective non-steroidal anti-inflammatory drugs","volume":"11","author":"Akarca","year":"2005","journal-title":"Current Pharmaceutical Design"},{"issue":"75","key":"10.1002\/14651858.CD008951.pub2-BIB0084|cit84","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0002-9343(83)90237-1","article-title":"Hepatotoxicity following the therapeutic use of antipyretic analgesics","volume":"14","author":"Benson","year":"1983","journal-title":"American Journal of Medicine"},{"issue":"2","key":"10.1002\/14651858.CD008951.pub2-BIB0085|cit85","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/01.mjt.0000140216.40700.95","article-title":"The therapeutic use of acetaminophen in patients with liver disease","volume":"12","author":"Benson","year":"2005","journal-title":"American Journal of Therapeutics"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0086|cit86","first-page":"5","article-title":"Social and economic impact of inflammatory arthritis","volume":"Spec No","author":"Bergmann","year":"2006","journal-title":"Postgraduate Medicine"},{"issue":"4","key":"10.1002\/14651858.CD008951.pub2-BIB0087|cit87","doi-asserted-by":"crossref","first-page":"269","DOI":"10.5055\/jom.2010.0025","article-title":"Burden of opioid-associated gastrointestinal side effects from clinical and economic perspectives: a systematic literature review","volume":"6","author":"Boswell","year":"2010","journal-title":"Journal of Opioid Management"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0088|cit88","doi-asserted-by":"crossref","unstructured":"Briggs A March L Reid C Lassere M Reid C Henderson L Baseline comorbidities in an Australian population-based cohort of rheumatoid arthritis patients receiving biological therapy: Data from the Australian Rheumatology Association Database (ARAD) International Journal of Rheumatology 2009","DOI":"10.1155\/2009\/861481"},{"issue":"12","key":"10.1002\/14651858.CD008951.pub2-BIB0089|cit89","first-page":"2281","article-title":"A new approach to defining functional ability in ankylosing spondylitis: the development of the Bath Ankylosing Spondylitis Functional Index","volume":"21","author":"Calin","year":"1994","journal-title":"Journal of Rheumatology"},{"issue":"12","key":"10.1002\/14651858.CD008951.pub2-BIB0090|cit90","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1111\/j.1365-2036.2008.03689.x","article-title":"Gastrointestinal side effects in chronic opioid users: results from a population-based survey","volume":"27","author":"Cook","year":"2008","journal-title":"Alimentary Pharmacology and Therapy"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0091|cit91","unstructured":"Khan KS ter Riet G Popay J Nixon N Kleijnen J Study quality assessment Undertaking Systematic Reviews of Research on Effectiveness. CRD's guidance for those carrying out or commissioning reviews. Report 4 March 2001"},{"issue":"2","key":"10.1002\/14651858.CD008951.pub2-BIB0092|cit92","first-page":"192","article-title":"Patients- and physicians- priorities for improvement. The case of rheumatic diseases","volume":"35","author":"Silva","year":"2001","journal-title":"Acta Reumatologica"},{"issue":"11","key":"10.1002\/14651858.CD008951.pub2-BIB0093|cit93","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1001\/jama.292.11.1363","article-title":"Clinical trial registration: a statement from the International Committee of Medical Journal Editors","volume":"292","author":"DeAngelis","year":"2004","journal-title":"JAMA"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0094|cit94","unstructured":"Deeks JJ Higgins JPT Altman DG (editors) Chapter 9: Analysing data and undertaking meta-analyses In: Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0095|cit95","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1136\/ard.62.1.20","article-title":"Development of the ASQoL: a quality of life instrument specific to ankylosing spondylitis","volume":"62","author":"Doward","year":"2003","journal-title":"Annals of Rheumatic Disease"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0096|cit96","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1002\/1529-0131(199909)42:9<1854::AID-ANR9>3.0.CO;2-F","article-title":"Long-term course and outcome of functional capacity in rheumatoid arthritis - The effect of disease activity and radiologic damage over time","volume":"42","author":"Drossaers-Bakker","year":"1999","journal-title":"Arthritis and Rheumatism"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0097|cit97","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1136\/bmj.332.7534.152","article-title":"Treatment of rheumatoid arthritis","volume":"332","author":"Emery","year":"2006","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0098|cit98","unstructured":"EPOC data collection checklist http:\/\/epoc.cochrane.org\/epoc-resources-review-authors"},{"issue":"2","key":"10.1002\/14651858.CD008951.pub2-BIB0099|cit99","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1002\/art.1780230202","article-title":"Measurement of patient outcome in arthritis","volume":"23","author":"Fries","year":"1980","journal-title":"Arthritis and Rheumatism"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0100|cit100","first-page":"2475","article-title":"Comorbidity in arthritis","volume":"26","author":"Gabriel","year":"1999","journal-title":"Journal of Rheumatology"},{"issue":"4","key":"10.1002\/14651858.CD008951.pub2-BIB0101|cit101","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/art.10515","article-title":"Preferences for improved health examined in 1,024 patients with rheumatoid arthritis: pain has highest priority","volume":"47","author":"Heiberg","year":"2002","journal-title":"Arthritis and Rheumatism"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0102|cit102","first-page":"43","article-title":"Epidemiology overview of gastrointestinal and renal toxicity of NSAIDs","volume":"135","author":"Henry","year":"2003","journal-title":"International Journal of Clinical Practice"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0103|cit103","unstructured":"Higgins JPT Deeks JJ Chapter 7: Selecting studies and collecting data In: Higgins JPT, Green S, editors, Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0104|cit104","unstructured":"Higgins JPT Altman DG Sterne JAC (editors) Chapter 8: Assessing risk of bias in included studies In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0105|cit105","unstructured":"Higgins JPT Deeks JJ Altman DG (editors) Chapter 16: Special topics in statistics In: Higgins JPT, Green S (editors), Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011 ). The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org"},{"issue":"8","key":"10.1002\/14651858.CD008951.pub2-BIB0106|cit106","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1093\/rheumatology\/36.8.878","article-title":"The reliability and construct validity of the RAQoL: a rheumatoid arthritis-specific quality of life instrument","volume":"36","author":"Jong","year":"1997","journal-title":"British Journal of Rheumatology"},{"issue":"10","key":"10.1002\/14651858.CD008951.pub2-BIB0107|cit107","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008952.pub2","article-title":"Pain management for rheumatoid arthritis and cardiovascular or renal comorbidity","author":"Marks","year":"2011","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"5","key":"10.1002\/14651858.CD008951.pub2-BIB0108|cit108","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.berh.2007.06.002","article-title":"Comorbidities in rheumatoid arthritis","volume":"21","author":"Michaud","year":"2007","journal-title":"Best Practice & Research in Clinical Rheumatology"},{"issue":"5","key":"10.1002\/14651858.CD008951.pub2-BIB0109|cit109","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S1521-6942(03)00041-X","article-title":"Co-morbidity in rheumatoid arthritis","volume":"17","author":"Mikuls","year":"2003","journal-title":"Best Practice & Research in Clinical Rheumatology"},{"issue":"8","key":"10.1002\/14651858.CD008951.pub2-BIB0110|cit110","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1093\/rheumatology\/keg281","article-title":"Women with established rheumatoid arthritis perceive pain as the predominant impairment of health status","volume":"42","author":"Minnock","year":"2003","journal-title":"Rheumatology"},{"issue":"3","key":"10.1002\/14651858.CD008951.pub2-BIB0111|cit111","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.pain.2010.05.011","article-title":"ACTINPAIN Writing Group of the IASP Special Interest Group on Systematic Reviews in Pain Relief; Cochrane Pain, Palliative and Supportive Care Systematic Review Group Editors. \"Evidence\" in chronic pain--establishing best practice in the reporting of systematic reviews","volume":"150","author":"Moore","year":"2010","journal-title":"Pain"},{"issue":"6","key":"10.1002\/14651858.CD008951.pub2-BIB0112|cit112","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1097\/MOG.0b013e32833e91eb","article-title":"NSAID-induced gastrointestinal and cardiovascular injury","volume":"26","author":"Ng","year":"2010","journal-title":"Current Opinion in Gastroenterology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0113|cit113","doi-asserted-by":"crossref","unstructured":"Oldroyd J Schachna L Buchbinder R Staples M Briggs A Lassere M Reid C March L Baseline characteristics in an Australian population-based cohort of patients with ankylosing spondylitis commencing biological therapy: data from the Australian Rheumatology Association Database (ARAD) International Journal of Rheumatology 2009","DOI":"10.1155\/2009\/268569"},{"issue":"11","key":"10.1002\/14651858.CD008951.pub2-BIB0114|cit114","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1002\/art.1780261107","article-title":"Assessment of patient satisfaction in activities of daily living using a modified Stanford Health Assessment Questionnaire","volume":"26","author":"Pincus","year":"1983","journal-title":"Arthritis and Rheumatism"},{"issue":"4","key":"10.1002\/14651858.CD008951.pub2-BIB0115|cit115","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1046\/j.1365-2125.2000.00167.x","article-title":"Paracetamol, alcohol and the liver","volume":"49","author":"Prescott","year":"2000","journal-title":"British Journal of Clinical Pharmacology"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0116|cit116","unstructured":"Sch\u00fcnemann HJ Oxman AD Vist GE Higgins JPT Deeks JJ Glasziou P Guyatt GH Chapter 12: Interpreting results and drawing conclusions In: Higgins JPT, Green S, editors, Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0117|cit117","unstructured":"Sch\u00fcnemann HJ Oxman AD Higgins JP Vist GE Glasziou P Guyatt GH Chapter 11: Presenting results and 'Summary of findings' tables In: Higgins JPT, Green S (editors), Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org"},{"issue":"13","key":"10.1002\/14651858.CD008951.pub2-BIB0118|cit118","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1001\/jama.284.10.1247","article-title":"Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study","volume":"284","author":"Silverstein","year":"2000","journal-title":"JAMA"},{"issue":"20","key":"10.1002\/14651858.CD008951.pub2-BIB0119|cit119","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1001\/jama.282.20.1921","article-title":"Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: a randomized controlled trial.","volume":"282","author":"Simon","year":"1999","journal-title":"JAMA"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0120|cit120","first-page":"18","article-title":"Epidemiology NSAID induced gastrointestinal complications","volume":"26 Suppl 56","author":"Singh","year":"1999","journal-title":"Journal of Rheumatology"},{"issue":"6","key":"10.1002\/14651858.CD008951.pub2-BIB0121|cit121","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1136\/ard.2009.126532","article-title":"EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs","volume":"69","author":"Smolen","year":"2010","journal-title":"Annals of Rheumatic Disease"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0122|cit122","unstructured":"Sterne JAC Egger M Moher D (editors) Chapter 10: Addressing reporting biases Chapter 10: Addressing reporting biases. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Intervention. Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0123|cit123","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/00005650-199206000-00002","article-title":"The Mos 36-Item Short-Form Health Survey (SF-36). 1. Conceptual-Framework and Item Selection","volume":"30","author":"Ware","year":"1992","journal-title":"Medical Care"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0124|cit124","unstructured":"Wells GA Shea B O'Connell D The Newcastle-Ottawa Scale (NOS) for assessing the quality if nonrandomized studies in meta-analyses Available from: URL: http:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.htm 2009"},{"key":"10.1002\/14651858.CD008951.pub2-BIB0125|cit125","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1056\/NEJM199906173402407","article-title":"Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs","volume":"340","author":"Wolfe","year":"1999","journal-title":"New England Journal of Medicine"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/14651858.CD008951.pub2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T15:01:36Z","timestamp":1749740496000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD008951.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Musculoskeletal Group","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2012,1,18]]},"references-count":125,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2012,2]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd008951.pub2","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,18]]}}}