{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T14:54:53Z","timestamp":1772117693988,"version":"3.50.1"},"update-to":[{"DOI":"10.1002\/14651858.cd009429","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2012,10,17]],"date-time":"2012-10-17T00:00:00Z","timestamp":1350432000000}}],"reference-count":27,"publisher":"Wiley","issue":"10","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd009429.pub2","type":"journal-article","created":{"date-parts":[[2012,10,11]],"date-time":"2012-10-11T13:20:37Z","timestamp":1349961637000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Pregabalin monotherapy for epilepsy"],"prefix":"10.1002","volume":"2012","author":[{"given":"Qin","family":"Zhou","sequence":"first","affiliation":[{"name":"First Affiliated Hospital, Guangxi Medical University; Department of Neurology; 6 Shuangyong Road Nanning Guangxi China 530021"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinou","family":"Zheng","sequence":"additional","affiliation":[{"name":"First Affiliated Hospital, Guangxi Medical University; Department of Neurology; 6 Shuangyong Road Nanning Guangxi China 530021"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu","family":"Yu","sequence":"additional","affiliation":[{"name":"First Affiliated Hospital, Guangxi Medical University; Department of Neurology; 6 Shuangyong Road Nanning Guangxi China 530021"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyan","family":"Jia","sequence":"additional","affiliation":[{"name":"First Affiliated Hospital, Guangxi Medical University; Department of Neurology; 6 Shuangyong Road Nanning Guangxi China 530021"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,10,17]]},"reference":[{"issue":"Suppl 7","key":"10.1002\/14651858.CD009429.pub2-BIB0001|cit1","first-page":"109","article-title":"Pregabalin in-patient monotherapy trial - study results and impact of seizure frequency on efficacy evaluations","volume":"40","author":"Abou-Khalil","year":"1999","journal-title":"Epilepsia"},{"issue":"10","key":"10.1002\/14651858.CD009429.pub2-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/S1474-4422(11)70154-5","article-title":"Efficacy and safety of pregabalin versus lamotrigine in patients with newly diagnosed partial seizures: a phase 3, double-blind, randomised, parallel-group trial","volume":"10","author":"Kwan","year":"2011","journal-title":"The Lancet Neurology\u00a0"},{"issue":"1-3","key":"10.1002\/14651858.CD009429.pub2-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0920-1211(01)00220-0","article-title":"Monotherapy trials: presurgical studies","volume":"45","author":"Pledger","year":"2011","journal-title":"Epilepsy Research"},{"issue":"Suppl 6","key":"10.1002\/14651858.CD009429.pub2-BIB0004|cit4","first-page":"67","article-title":"Pregabalin monotherapy in hospitalized patients a study design for early demonstration of anticonvulsant efficacy","volume":"39","author":"Vazquez","year":"1998","journal-title":"Epilepsia"},{"key":"10.1002\/14651858.CD009429.pub2-BIB0005|cit5","unstructured":"NCT00280059 Study Of The Safety And Efficacy Of Lyrica In The Treatment Of Newly Diagnosed Partial Epilepsy clinicaltrials.gov\/show\/NCT00280059"},{"key":"10.1002\/14651858.CD009429.pub2-BIB0006|cit6","unstructured":"NCT00351611 Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or Placebo clinicaltrials.gov\/show\/NCT00351611"},{"key":"10.1002\/14651858.CD009429.pub2-BIB0007|cit7","unstructured":"NCT00437281 Safety, Tolerability, and Pharmacokinetic Study of Pregabalin in Pediatric Patients With Partial Onset Seizures clinicaltrials.gov\/show\/NCT00437281"},{"key":"10.1002\/14651858.CD009429.pub2-BIB0008|cit8","unstructured":"NCT00524030 Efficacy And Safety Study Of Pregabalin (Lyrica) As Monotherapy In Patients With Partial Seizures clinicaltrials.gov\/show\/NCT00524030"},{"key":"10.1002\/14651858.CD009429.pub2-BIB0009|cit9","unstructured":"NCT00552526 Ketogenic Diet vs.Antiepileptic Drug Treatment in Drug Resistant Epilepsy clinicaltrials.gov\/show\/NCT00552526"},{"key":"10.1002\/14651858.CD009429.pub2-BIB0010|cit10","unstructured":"NCT00629889 Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and\/or Radiation Therapy For Primary Brain Tumors clinicaltrial.gov\/show\/NCT00629889"},{"issue":"7","key":"10.1002\/14651858.CD009429.pub2-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1111\/j.1528-1157.1998.tb01167.x","article-title":"Consideration on designing clinical trials to evaluate the place of new antiepileptic drugs in the treatment of newly diagnosed and chronic patients with epilepsy","volume":"39","author":"ILAE Commission on Antiepileptic Drugs","year":"1998","journal-title":"Epilepsia"},{"key":"10.1002\/14651858.CD009429.pub2-BIB0012|cit12","unstructured":"Deeks JJ Higgins JPT Altman DG Chapter 9: Analysing data and undertaking meta-analyses In: Higgins JPT, Green S (editors) Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011) The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org"},{"key":"10.1002\/14651858.CD009429.pub2-BIB0013|cit13","unstructured":"Higgins JPT Altman DG Sterne JAC Chapter 8: \u00a0Assessing risk of bias in included studies. In: Higgins JPT, Green S (editors). CochraneHandbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration Available from www.cochrane-handbook.org"},{"key":"10.1002\/14651858.CD009429.pub2-BIB0014|cit14","unstructured":"Higgins JPT Deeks JJ Chapter 7: Selecting studies and collecting data In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from www.cochrane-handbook.org"},{"key":"10.1002\/14651858.CD009429.pub2-BIB0015|cit15","unstructured":"Higgins JPT Deeks JJ Altman DG Chapter 16: Special topics in statistics. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from www.cochrane-handbook.org"},{"issue":"4","key":"10.1002\/14651858.CD009429.pub2-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"549\u201356","DOI":"10.1111\/j.1528-1167.2008.01546.x","article-title":"Clinical picture of EPM1-Unverricht-Lundborg disease","volume":"49","author":"Kalviainen","year":"2008","journal-title":"Epilepsia"},{"key":"10.1002\/14651858.CD009429.pub2-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1517\/13543784.12.4.663","article-title":"Pregabalin: a new anxiolytic","volume":"12","author":"Lauria-Horner","year":"2003","journal-title":"Expert Opinion on Investigational Drugs"},{"key":"10.1002\/14651858.CD009429.pub2-BIB0018|cit18","unstructured":"Lefebvre C Manheimer E Glanville J Chapter 6: Searching for studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.2 (updated September 2009). The Cochrane Collaboration, 2009 Available from www.cochrane-handbook.org"},{"issue":"1","key":"10.1002\/14651858.CD009429.pub2-BIB0019|cit19","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005612.pub2","article-title":"Pregabalin add-on for drug-resistant partial epilepsy","author":"Lozsadi","year":"2008","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"2","key":"10.1002\/14651858.CD009429.pub2-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S1734-1140(09)70024-6","article-title":"Third-generation antiepileptic drugs: mechanisms of action, pharmacokinetics and interactions","volume":"61","author":"Luszczki","year":"2009","journal-title":"Pharmacological Reports"},{"issue":"9566","key":"10.1002\/14651858.CD009429.pub2-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/S0140-6736(07)60460-7","article-title":"The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial","volume":"369","author":"Marson","year":"2007","journal-title":"Lancet"},{"issue":"24","key":"10.1002\/14651858.CD009429.pub2-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"2815","DOI":"10.1002\/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0.CO;2-8","article-title":"Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints","volume":"17","author":"Parmar","year":"1998","journal-title":"Statistics in Medicine"},{"key":"10.1002\/14651858.CD009429.pub2-BIB0023|cit23","unstructured":"The Nordic Cochrane Centre, The Cochrane Collaboration Review Manager (RevMan) 2011"},{"key":"10.1002\/14651858.CD009429.pub2-BIB0024|cit24","unstructured":"World Health Organization Epilepsy Available from www.who.int\/mediacentre\/factsheets\/fs999\/en\/ 2009"},{"key":"10.1002\/14651858.CD009429.pub2-BIB0025|cit25","unstructured":"World Health Organization Management of epilepsy Available from www.searo.who.int\/LinkFiles\/Information_and_Documents_management.pdf 2010"},{"issue":"2-3","key":"10.1002\/14651858.CD009429.pub2-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.eplepsyres.2009.08.001","article-title":"The long-term retention of pregabalin in a large cohort of patients with epilepsy at a tertiary referral centre","volume":"87","author":"Yuen","year":"2009","journal-title":"Epilepsy Research"},{"issue":"4","key":"10.1002\/14651858.CD009429.pub2-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1111\/j.1528-1167.2010.02966.x","article-title":"The adverse event profile of pregabalin: a systematic review and meta-analysis of randomized controlled trials","volume":"52","author":"Zaccara","year":"2011","journal-title":"Epilepsia"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/14651858.CD009429.pub2\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,29]],"date-time":"2025-03-29T10:16:57Z","timestamp":1743243417000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD009429.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Epilepsy Group","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2012,10,17]]},"references-count":27,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2012,10]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd009429.pub2","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.717962208.793468538","asserted-by":"object"}]},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,17]]}}}