{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T01:00:57Z","timestamp":1789952457563,"version":"4.0.1"},"update-to":[{"DOI":"10.1002\/14651858.cd010461.pub3","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000}}],"reference-count":93,"publisher":"Wiley","issue":"6","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd010461.pub4","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T11:10:09Z","timestamp":1780398609000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Advanced sperm selection techniques for assisted reproduction"],"prefix":"10.1002","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1051-967X","authenticated-orcid":false,"given":"Akanksha","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology; Yale School of Medicine; New Haven Connecticut USA"},{"name":"Department of Metabolism, Digestion and Reproduction; Imperial College London; London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Nakhla","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynaecology and Newborn Health; University of Melbourne; Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Steeper","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynaecology and Newborn Health; University of Melbourne; Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afsana","family":"Afroz","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynaecology and Newborn Health; University of Melbourne; Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Lepine","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology; Tauranga Hospital; Tauranga New Zealand"},{"name":"Fertility Medicine; Fertility Associates; Tauranga New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon J","family":"McDowell","sequence":"additional","affiliation":[{"name":"Fertility Associates; Wellington New Zealand"},{"name":"Department of Obstetrics & Gynaecology; Capital & Coast District Health Board; Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Kroon","sequence":"additional","affiliation":[{"name":"Monash IVF; Brisbane Australia"},{"name":"The University of Queensland; Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Demi\u00e1n","family":"Glujovsky","sequence":"additional","affiliation":[{"name":"Reproductive Medicine; CEGYR (Centro de Estudios en Gen\u00e9tica y Reproducci\u00f3n); Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anusch","family":"Yazdani","sequence":"additional","affiliation":[{"name":"Queensland Fertility Group Research Foundation; Brisbane Australia"},{"name":"The University of Queensland; Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Lensen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynaecology and Newborn Health; University of Melbourne; Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"issue":"10515","key":"10.1002\/14651858.CD010461.pub4-BIB0001|cit1","doi-asserted-by":"publisher","first-page":"2100","DOI":"10.1016\/s0140-6736(25)01188-2","article-title":"Partial progress in sexual and reproductive health and rights: the influence of sociocultural, behavioural, structural, and technological changes on epidemiological trends","volume":"406","author":"Grulich","year":"2025","journal-title":"Lancet"},{"issue":"12","key":"10.1002\/14651858.CD010461.pub4-BIB0002|cit2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD014040.pub2","article-title":"Oocyte activation for women following intracytoplasmic sperm injection (ICSI)","author":"Kamath","year":"2024","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"8810","key":"10.1002\/14651858.CD010461.pub4-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0140-6736(92)92425-F","article-title":"Pregnancies after intracytoplasmic injection of a single spermatozoon into an oocyte","volume":"340","author":"Palermo","year":"1992","journal-title":"Lancet"},{"issue":"1","key":"10.1002\/14651858.CD010461.pub4-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1080\/1464727002000198651","article-title":"Possible consequences of performing ICSI with sperm possessing nuclear DNA damage","volume":"3","author":"Sakkas","year":"2000","journal-title":"Human Fertility"},{"issue":"05\/06","key":"10.1002\/14651858.CD010461.pub4-BIB0005|cit5","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1055\/s-0041-1732313","article-title":"Sperm selection technology in ART","volume":"39","author":"Martin","year":"2021","journal-title":"Seminars in Reproductive Medicine"},{"issue":"4","key":"10.1002\/14651858.CD010461.pub4-BIB0006|cit6","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004507.pub3","article-title":"Semen preparation techniques for intrauterine insemination","author":"Boomsma","year":"2007","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"8","key":"10.1002\/14651858.CD010461.pub4-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1093\/humrep\/dei024","article-title":"Development of a novel electrophoretic system for the isolation of human spermatozoa","volume":"20","author":"Ainsworth","year":"2005","journal-title":"Human Reproduction (Oxford, England)"},{"issue":"3","key":"10.1002\/14651858.CD010461.pub4-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1023\/A:1020188913551","article-title":"Enrichment of non-apoptotic human spermatozoa after cryopreservation by immunomagnetic cell sorting","volume":"2","author":"Grunewald","year":"2001","journal-title":"Cell and Tissue Banking"},{"issue":"10170","key":"10.1002\/14651858.CD010461.pub4-BIB0009|cit9","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1016\/s0140-6736(18)32989-1","article-title":"Physiological, hyaluronan-selected intracytoplasmic sperm injection for infertility treatment (HABSelect): a parallel, two-group, randomised trial","volume":"393","author":"Miller","year":"2019","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/S1472-6483(10)61060-7","article-title":"Fertility testing and ICSI sperm selection by hyaluronic acid binding: clinical and genetic aspect","volume":"14","author":"Huszar","year":"2007","journal-title":"Reproductive Biomedicine Online"},{"issue":"2","key":"10.1002\/14651858.CD010461.pub4-BIB0011|cit11","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1017\/s0967199422000685","article-title":"Comparative study between SpermSlow\u2122 hyaluronan and traditional sperm selection in ICSI outcome","volume":"31","author":"Abd Elraouf","year":"2023","journal-title":"Zygote (Cambridge, England)"},{"issue":"1","key":"10.1002\/14651858.CD010461.pub4-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.fertnstert.2007.05.078","article-title":"Sperm head\u2019s birefringence: a new criterion for sperm selection","volume":"90","author":"Gianaroli","year":"2008","journal-title":"Fertility and Sterility"},{"issue":"10","key":"10.1002\/14651858.CD010461.pub4-BIB0013|cit13","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1096\/fba.2024-00041","article-title":"Microfluidics-a novel technique for high-quality sperm selection for greater ART outcomes","volume":"6","author":"Bhat","year":"2024","journal-title":"FASEB BioAdvances"},{"issue":"1","key":"10.1002\/14651858.CD010461.pub4-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/j.1939-4640.2002.tb02595.x","article-title":"Real-time fine morphology of motile human sperm cells is associated with IVF-ICSI outcome","volume":"23","author":"Bartoov","year":"2002","journal-title":"Journal of Andrology"},{"issue":"6","key":"10.1002\/14651858.CD010461.pub4-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1016\/j.fertnstert.2003.05.016","article-title":"Pregnancy rates are higher with intracytoplasmic morphologically selected sperm injection than with conventional intracytoplasmic injection","volume":"80","author":"Bartoov","year":"2003","journal-title":"Fertility and Sterility"},{"issue":"7","key":"10.1002\/14651858.CD010461.pub4-BIB0016|cit16","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010167.pub2","article-title":"Regular (ICSI) versus ultra-high magnification (IMSI) sperm selection for assisted reproduction","author":"Teixeira","year":"2013","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/S1472-6483(10)60676-1","article-title":"Origins and consequences of DNA damage in male germ cells","volume":"14","author":"Aitken","year":"2007","journal-title":"Reproductive Biomedicine Online"},{"issue":"4","key":"10.1002\/14651858.CD010461.pub4-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.fertnstert.2012.12.025","article-title":"Novel technologies for selecting the best sperm for in vitro fertilization and intracytoplasmic sperm injection","volume":"99","author":"Sakkas","year":"2013","journal-title":"Fertility and Sterility"},{"issue":"10","key":"10.1002\/14651858.CD010461.pub4-BIB0019|cit19","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010461.pub2","article-title":"Advanced sperm selection techniques for assisted reproduction","author":"McDowell","year":"2014","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"7","key":"10.1002\/14651858.CD010461.pub4-BIB0020|cit20","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010461.pub3","article-title":"Advanced sperm selection techniques for assisted reproduction","author":"Lepine","year":"2019","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0021|cit21","unstructured":"Higgins JPT Lasserson T Thomas J Flemyng E Churchill R Methodological expectations of Cochrane intervention reviews (MECIR). Cochrane, August 2023 Available from https:\/\/www.cochrane.org\/authors\/handbooks-and-manuals\/mecir-manual"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0022|cit22","doi-asserted-by":"publisher","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"issue":"3","key":"10.1002\/14651858.CD010461.pub4-BIB0023|cit23","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010461","article-title":"Advanced sperm selection techniques for assisted reproduction","author":"McDowell","year":"2013","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"1","key":"10.1002\/14651858.CD010461.pub4-BIB0024|cit24","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/s41073-023-00130-8","article-title":"Checklist to assess Trustworthiness in RAndomised Controlled Trials (TRACT checklist): concept proposal and pilot","volume":"8","author":"Mol","year":"2023","journal-title":"Research Integrity and Peer Review"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0025|cit25","doi-asserted-by":"publisher","first-page":"d5928","DOI":"10.1136\/bmj.d5928","article-title":"The Cochrane Collaboration\u2019s tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0026|cit26","unstructured":"Higgins JP Green S Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011 Available from https:\/\/www.cochrane.org\/handbook"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0027|cit27","unstructured":"Review Manager (RevMan) The Nordic Cochrane Centre, The Cochrane Collaboration 2014"},{"issue":"7414","key":"10.1002\/14651858.CD010461.pub4-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1093\/ije\/dyn204","article-title":"Heterogeneity in meta-analysis should be expected and appropriately quantified","volume":"37","author":"Higgins","year":"2008","journal-title":"International Journal of Epidemiology"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0030|cit30","unstructured":"GRADEpro GDT McMaster University (developed by Evidence Prime)"},{"issue":"3","key":"10.1002\/14651858.CD010461.pub4-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.fertnstert.2012.05.043","article-title":"Comparison of two ready-to-use systems designed for sperm-hyaluronic acid binding selection before intracytoplasmic sperm injection: PICSI vs. Sperm Slow: a prospective, randomized trial","volume":"98","author":"Parmegiani","year":"2012","journal-title":"Fertility and Sterility"},{"issue":"Suppl 2","key":"10.1002\/14651858.CD010461.pub4-BIB0032|cit32","first-page":"ii121\u201350","article-title":"Sperm-hyaluronic acid (HA) binding selection: PICSE versus sperm slow: P-077","volume":"27","author":"Parmegiani","year":"2012","journal-title":"Human Reproduction (Oxford, England)"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0033|cit33","unstructured":"Comparison of two ready-to-use systems specially designed for physiological intracytoplasmic sperm injection (ICSI): PICSI versus Sperm Slow, a prospective randomised trial https:\/\/trialsearch.who.int\/Trial2.aspx?TrialID=ISRCTN72668039"},{"issue":"2","key":"10.1002\/14651858.CD010461.pub4-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1093\/humrep\/des417","article-title":"Use of hyaluronan in the selection of sperm for intracytoplasmic sperm injection (ICSI): significant improvement in clinical outcomes - multicenter, double-blinded and randomized controlled trial","volume":"28","author":"Worrilow","year":"2013","journal-title":"Human Reproduction (Oxford, England)"},{"issue":"Suppl 3","key":"10.1002\/14651858.CD010461.pub4-BIB0035|cit35","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.1016\/j.fertnstert.2011.07.221","article-title":"Prospective, multi-center, double-blind, randomized clinical trial evaluating the use of hyaluronan bound sperm (HBS) in ICSI: statistically significant improvement in clinical outcomes","volume":"96","author":"Worrilow","year":"2011","journal-title":"Fertility and Sterility"},{"issue":"3","key":"10.1002\/14651858.CD010461.pub4-BIB0036|cit36","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1007\/s10815-018-1375-2","article-title":"Effects of the microfluidic chip technique in sperm selection for intracytoplasmic sperm injection for unexplained infertility: a prospective, randomized controlled trial","volume":"36","author":"Yetkinel","year":"2019","journal-title":"Journal of Assisted Reproduction and Genetics"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0037|cit37","unstructured":"The effects of using fertile chip in sperm selection for intracytoplasmic sperm injection in unexplained infertility https:\/\/clinicaltrials.gov\/ct2\/show\/NCT02488434"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0038|cit38","first-page":"253","article-title":"Zeta sperm selection improves pregnancy rates and alters sex ratio in male factor infertility patients: a double-blind, randomized clinical trial","volume":"10","author":"Esfahani","year":"2016","journal-title":"International Journal of Fertility and Sterility"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/S0140-6736(18)32989-1","article-title":"Physiological, hyaluronan-selected intracytoplasmic sperm injection for infertility treatment (HABSelect): a parallel, two-group, randomised trial","volume":"393","author":"Miller","year":"2019","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0040|cit40","doi-asserted-by":"crossref","unstructured":"Witt KD Beresford L Bhattacharya S Correction: Hyaluronic Acid Binding Sperm Selection for assisted reproduction treatment (HABSelect): study protocol for a multicentre randomised controlled trial BMJ Open 2017 10.1136\/bmjopen-2016-012609corr1","DOI":"10.1136\/bmjopen-2016-012609"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0041|cit41","doi-asserted-by":"crossref","unstructured":"Kirkman-Brown J Pavitt S Khalaf Y Lewis S Hooper R Bhattacharya S Sperm selection for assisted reproduction by prior hyaluronan binding: the HABSelect RCT NIHR Journals Library 2019 6.1 10.3310\/eme06010","DOI":"10.3310\/eme06010"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0042|cit42","unstructured":"HABSelect: a new sperm selection process for ICSI (Intracytoplasmic Sperm Injection) aimed at increasing live birth outcomes and reducing miscarriage rates https:\/\/trialsearch.who.int\/Trial2.aspx?TrialID=ISRCTN99214271"},{"issue":"11","key":"10.1002\/14651858.CD010461.pub4-BIB0043|cit43","doi-asserted-by":"publisher","first-page":"1471EP","DOI":"10.1007\/s10815-013-0108-9","article-title":"A prospective randomized study to evaluate the effect of hyaluronic acid sperm selection on the intracytoplasmic sperm injection outcome of patients with unexplained infertility having normal semen parameters","volume":"30","author":"Majumdar","year":"2013","journal-title":"Journal of Assisted Reproduction and Genetics"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0044|cit44","doi-asserted-by":"publisher","first-page":"i122","DOI":"10.1093\/humrep\/30.Supplement-1.1","article-title":"Sperm selection using MACS has similar obstetric and perinatal outcomes than standard preparation when ICSI was performed in ovum donation in a prospective and randomized trial","volume":"30","author":"Romany","year":"2015","journal-title":"Human Reproduction (Oxford, England)"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0045|cit45","doi-asserted-by":"publisher","first-page":"i45","DOI":"10.1093\/humrep\/29.Supplement_1.1","article-title":"Sperm selection using MACS technology does not improve live-birth delivery rates when ICSI was performed in ovum donation. Prospective and randomized trial in unselected males","volume":"29","author":"Romany","year":"2014","journal-title":"Human Reproduction (Oxford, England)"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0046|cit46","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1016\/j.fertnstert.2014.09.001","article-title":"Removal of annexin V-positive sperm cells for intracytoplasmic sperm injection in ovum donation cycles does not improve reproductive outcome: a controlled and randomized trial in unselected males","volume":"102","author":"Romany","year":"2014","journal-title":"Fertility and Sterility"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0047|cit47","doi-asserted-by":"crossref","first-page":"66","DOI":"10.5935\/1518-0557.20150015","article-title":"Annexin V-MACS in infertile couples as method for separation of sperm without DNA fragmentation","volume":"19","author":"Troya","year":"2015","journal-title":"JBRA Assisted Reproduction"},{"issue":"2","key":"10.1002\/14651858.CD010461.pub4-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1080\/14647273.2018.1424354","article-title":"Clinical outcomes of magnetic activated sperm sorting in infertile men candidate for ICSI","volume":"22","author":"Ziarati","year":"2018","journal-title":"Human Fertility"},{"issue":"2","key":"10.1002\/14651858.CD010461.pub4-BIB0049|cit49","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1080\/14647273.2018.1424354","article-title":"Clinical outcomes of magnetic activated sperm sorting in infertile men candidate for ICSI","volume":"22","author":"Ziarati","year":"2019","journal-title":"Human Fertility (Cambridge)"},{"issue":"2","key":"10.1002\/14651858.CD010461.pub4-BIB0050|cit50","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1016\/j.fertnstert.2021.12.012","article-title":"The sixth edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen: ensuring quality and standardization in basic examination of human ejaculates","volume":"117","author":"Bj\u00f6rndahl","year":"2022","journal-title":"Fertility and Sterility"},{"issue":"5","key":"10.1002\/14651858.CD010461.pub4-BIB0051|cit51","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/S1472-6483(10)61191-1","article-title":"How to improve IVF-ICSI outcome by sperm selection","volume":"12","author":"Berkovitz","year":"2006","journal-title":"Reproductive Biomedicine Online"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0052|cit52","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1017\/S0967199413000191","article-title":"Traditional intracytoplasmic sperm injection provides equivalent outcomes compared with human zona-pellucida-bound selected sperm injection","volume":"22","author":"Casciani","year":"2013","journal-title":"Zygote (Cambridge, England)"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0053|cit53","first-page":"21","article-title":"Selection of sperm based on hypo-osmotic swelling may improve ICSI outcome: a preliminary prospective clinical trial","volume":"8","author":"Charehjooy","year":"2014","journal-title":"International Journal of Fertility and Sterility"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD010461.pub4-BIB0054|cit54","first-page":"A1","article-title":"First prospective controlled trial of a novel membrane-based electrophoretic method of isolating spermatozoa for IVF","volume":"47","author":"Fleming","year":"2007","journal-title":"Australian & New Zealand Journal of Obstetrics & Gynaecology"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0055|cit55","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1111\/j.1439-0272.2011.01258.x","article-title":"Selection of birefringent spermatozoa under Polscope: effect on intracytoplasmic sperm injection outcome","volume":"44","author":"Ghosh","year":"2011","journal-title":"Andrologia"},{"issue":"3","key":"10.1002\/14651858.CD010461.pub4-BIB0056|cit56","doi-asserted-by":"crossref","first-page":"S224","DOI":"10.1016\/j.fertnstert.2009.07.1538","article-title":"Sperm selection by ? By-pass insemination? And clinical result","volume":"92","author":"Han","year":"2009","journal-title":"Fertility and Sterility"},{"issue":"1","key":"10.1002\/14651858.CD010461.pub4-BIB0057|cit57","first-page":"17","article-title":"MACS-DGC versus DGC sperm wash procedure: comparing clinical outcomes in couples with male factor infertility undergoing ICSI: a clinical trial study","volume":"16","author":"Norozi-Hafshejani","year":"2022","journal-title":"International Journal of Fertility and Sterility"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0058|cit58","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s10815-009-9380-0","article-title":"Efficiency of hyaluronic acid (HA) sperm selection","volume":"27","author":"Parmegiani","year":"2010","journal-title":"Journal of Assisted Reproduction and Genetics"},{"issue":"6","key":"10.1002\/14651858.CD010461.pub4-BIB0059|cit59","doi-asserted-by":"crossref","first-page":"1408EP","DOI":"10.1080\/14647273.2023.2236297","article-title":"MACS-DGC sperm preparation method resulted in high-quality sperm, top-quality embryo, and higher blastocyst rate in male factor infertile couples with high DNA fragmented sperm","volume":"26","author":"Salehi Novin","year":"2023","journal-title":"Human Fertility"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0060|cit60","first-page":"i118","article-title":"Magnetic Activated Cell Sorting (MACS) is a useful technique to improved pregnancy rate in patients with high level of sperm DNA fragmentation","volume":"28 (Suppl 1)","author":"San Carchenilla","year":"2013","journal-title":"Human Reproduction (Oxford, England)"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0061|cit61","first-page":"i199","article-title":"Magnetic-activated cell sorting of non-apoptotic spermatozoa improves the good quality blastocyst rate in women over 30 years old: a prospective study in sibling oocytes","volume":"32 (Suppl 1)","author":"Stimpfel","year":"2017","journal-title":"Human Reproduction. Conference"},{"issue":"6","key":"10.1002\/14651858.CD010461.pub4-BIB0062|cit62","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1093\/humrep\/deac058","article-title":"Sperm selection with hyaluronic acid improved live birth outcomes among older couples and was connected to sperm DNA quality, potentially affecting all treatment outcomes","volume":"37","author":"West","year":"2022","journal-title":"Human Reproduction (Oxford, England)"},{"issue":"3","key":"10.1002\/14651858.CD010461.pub4-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/j.fertnstert.2008.10.024","article-title":"Birefringence characteristics in sperm heads allow for the selection of reacted spermatozoa for intracytoplasmic sperm injection","volume":"93","author":"Gianaroli","year":"2010","journal-title":"Fertility and Sterility"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0064|cit64","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1007\/s10815-016-0676-6","article-title":"Outcomes of intracytoplasmic sperm injection using the zona pellucida-bound sperm or manually selected sperm","volume":"33","author":"Jin","year":"2016","journal-title":"Journal of Assisted Reproduction and Genetics"},{"issue":"1","key":"10.1002\/14651858.CD010461.pub4-BIB0065|cit65","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s12958-017-0279-9","article-title":"Retraction Note: intracytoplasmic morphologically selected sperm injection versus conventional intracytoplasmic sperm injection: a randomized controlled trial","volume":"15","author":"Battista La Sala","year":"2017","journal-title":"Reproductive Biology and Endocrinology: RB&E"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0066|cit66","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/s12958-020-00642-8","article-title":"A fast and safe technique for sperm preparation in ICSI treatments within a randomized controlled trial (RCT)","volume":"18","author":"Baldini","year":"2020","journal-title":"Reproductive Biology and Endocrinology"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0067|cit67","unstructured":"Sperm selection by microfluidic separation improves embryo quality in patients with a history of poor embryo quality https:\/\/clinicaltrials.gov\/show\/NCT03085433 2017"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0068|cit68","doi-asserted-by":"publisher","first-page":"i184","DOI":"10.1093\/humrep\/dead093.365","article-title":"Can advanced sperm selection techniques improve blastocyst euploidy rate of abnormal sperm DNA fragmentation cases to the level of normal ones; prospective randomized controlled trial","volume":"38","author":"Hasanen","year":"2023","journal-title":"Human Reproduction (Oxford, England)"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0069|cit69","unstructured":"Advanced sperm selection techniques and their contribution to blastocyst euploidy rates https:\/\/clinicaltrials.gov\/ct2\/show\/NCT05494216 2022"},{"issue":"2","key":"10.1002\/14651858.CD010461.pub4-BIB0070|cit70","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.fertnstert.2009.03.033","article-title":"\"Physiologic ICSI\": hyaluronic acid (HA) favors selection of spermatozoa without DNA fragmentation and with normal nucleus, resulting in improvement of embryo quality","volume":"93","author":"Parmegiani","year":"2010","journal-title":"Fertility and Sterility"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD010461.pub4-BIB0071|cit71","first-page":"i165","article-title":"A prospective randomized trial to verify the efficacy of IMSI procedure in daily IVF routine","volume":"23","author":"Antinori","year":"2008","journal-title":"Human Reproduction (Oxford, England)"},{"issue":"6","key":"10.1002\/14651858.CD010461.pub4-BIB0072|cit72","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S1472-6483(10)60150-2","article-title":"Intracytoplasmic morphologically selected sperm injection: a prospective randomized trial","volume":"16","author":"Antinori","year":"2008","journal-title":"Reproductive Biomedicine Online"},{"issue":"5","key":"10.1002\/14651858.CD010461.pub4-BIB0073|cit73","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.rbmo.2010.11.003","article-title":"Clinical outcome of intracytoplasmic injection of spermatozoa morphologically selected under high magnification: a prospective randomized study","volume":"22","author":"Balaban","year":"2011","journal-title":"Reproductive Biomedicine Online"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0074|cit74","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1111\/j.1365-2605.2010.01066.x","article-title":"Sperm morphology assessment using David's classification: time to switch to strict criteria? Prospective comparative analysis in a selected IVF population?","volume":"34","author":"Blanchard","year":"2010","journal-title":"International Journal of Andrology"},{"issue":"3","key":"10.1002\/14651858.CD010461.pub4-BIB0075|cit75","doi-asserted-by":"crossref","first-page":"e282","DOI":"10.1016\/j.fertnstert.2021.07.759","article-title":"Microfluidic sperm sorting (MFSS) or swim up : better technique to evaluate sperm DNA integrity","volume":"116","author":"Brahmbhatt","year":"2021","journal-title":"Fertility and Sterility"},{"issue":"3","key":"10.1002\/14651858.CD010461.pub4-BIB0076|cit76","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/j.fertnstert.2010.11.018","article-title":"Morphological nuclear integrity of sperm cells is associated with preimplantation genetic aneuploidy screening cycle outcomes","volume":"95","author":"Figueira","year":"2011","journal-title":"Fertility and Sterility"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0077|cit77","first-page":"250","article-title":"The role of morphological nuclear integrity of the sperm cells in preimplantation genetic aneuploidy screening cycles outcome","volume":"7","author":"Figueira","year":"2010","journal-title":"Journal fur Reproduktionsmedizin und Endokrinologie"},{"issue":"3","key":"10.1002\/14651858.CD010461.pub4-BIB0078|cit78","doi-asserted-by":"crossref","first-page":"e349","DOI":"10.1016\/j.fertnstert.2014.07.1178","article-title":"Are hyaluronic acid sperm selection and intracytoplasmic morphologically selected sperm injection effective in patients with teratozoospermia?","volume":"102","author":"Kim","year":"2014","journal-title":"Fertility and Sterility"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0079|cit79","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1186\/1477-7827-9-123","article-title":"The IMSI procedure improves poor embryo development in the same infertile couples with poor semen quality: a comparative prospective randomized study","volume":"9","author":"Knez","year":"2011","journal-title":"Reproductive Biology and Endocrinology"},{"issue":"2","key":"10.1002\/14651858.CD010461.pub4-BIB0080|cit80","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.rbmo.2012.03.011","article-title":"Intracytoplasmic morphologically selected sperm injection improves development and quality of preimplantation embryos in teratozoospermia patients","volume":"25","author":"Knez","year":"2012","journal-title":"Reproductive Biomedicine Online"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0081|cit81","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1080\/14647273.2017.1366077","article-title":"Intracytoplasmic sperm injection using hyaluronic acid of polyvinylpyrrolidone: a time-lapse sibling oocyte study","volume":"22","author":"Liu","year":"2017","journal-title":"Human Fertility"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD010461.pub4-BIB0082|cit82","first-page":"i181","article-title":"How and in which indication the IMSI could improve outcomes?","volume":"26","author":"Mahmoud","year":"2011","journal-title":"Human Reproduction (Oxford, England)"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0083|cit83","unstructured":"Magnetic activated cell sorting in artificial insemination with donor sperm https:\/\/clinicaltrials.gov\/show\/NCT03659812 2018"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0084|cit84","unstructured":"Microfluidic chip method versus density gradient centrifugation method on semen parameters https:\/\/clinicaltrials.gov\/ct2\/show\/NCT05978947 2023"},{"issue":"8","key":"10.1002\/14651858.CD010461.pub4-BIB0085|cit85","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.1016\/j.fertnstert.2011.03.003","article-title":"Intracytoplasmic morphologically selected sperm injection benefits for patients with oligoasthenozoospermia according to the 2010 World Health Organization reference values","volume":"95","author":"Setti","year":"2011","journal-title":"Fertility and Sterility"},{"issue":"4","key":"10.1002\/14651858.CD010461.pub4-BIB0086|cit86","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.rbmo.2012.01.007","article-title":"Gender incidence of intracytoplasmic morphologically selected sperm injection-derived embryos: a prospective randomized study","volume":"24","author":"Setti","year":"2012","journal-title":"Reproductive Biomedicine Online"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD010461.pub4-BIB0087|cit87","doi-asserted-by":"crossref","first-page":"i71","DOI":"10.1093\/humrep\/26.s1.48","article-title":"Gender incidence on intracytoplasmic morphologically selected sperm injection approach: a prospective randomized study","volume":"26","author":"Iaconelli","year":"2011","journal-title":"Human Reproduction (Oxford, England)"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0088|cit88","first-page":"286","article-title":"IMSI is beneficial in cases of advanced maternal age: a prospective randomized study","volume":"171","author":"Setti","year":"2012","journal-title":"Reproductive Biomedicine Online"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0089|cit89","unstructured":"Practice Committees of the American Society for Reproductive Medicine and the Society for Assisted Reproductive Technology The use of preimplantation genetic testing for aneuploidy: a committee opinion Fertility and Sterility 2024 122 421 34 10.1016\/j.fertnstert.2024.04.013"},{"issue":"9","key":"10.1002\/14651858.CD010461.pub4-BIB0090|cit90","doi-asserted-by":"crossref","first-page":"e0267652","DOI":"10.1371\/journal.pone.0267652","article-title":"Freeze all-first versus biopsy-first: A retrospective analysis of frozen blastocyst transfer cycles with preimplantation genetic testing for aneuploidy","volume":"17","author":"Yu","year":"2022","journal-title":"PLOS ONE"},{"key":"10.1002\/14651858.CD010461.pub4-BIB0091|cit91","doi-asserted-by":"crossref","first-page":"113","DOI":"10.5317\/wjog.v4.i4.113","article-title":"Use of hyaluronic acid for sperm immobilisation and selection before intracytoplasmic sperm injection: a systematic review and meta-analysis","volume":"4","author":"Craciunas","year":"2015","journal-title":"World Journal of Obstetrics and Gynaecology"},{"issue":"6","key":"10.1002\/14651858.CD010461.pub4-BIB0092|cit92","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1093\/humupd\/dmr032","article-title":"Effects of advanced selection methods on sperm quality and ART outcome: a systematic review","volume":"17","author":"Said","year":"2007","journal-title":"Human Reproduction Update"},{"issue":"22","key":"10.1002\/14651858.CD010461.pub4-BIB0093|cit93","doi-asserted-by":"publisher","first-page":"13859","DOI":"10.3390\/ijms232213859","article-title":"Advanced sperm selection strategies as a treatment for infertile couples: a systematic review","volume":"23","author":"Ribas-Maynou","year":"2022","journal-title":"International Journal of Molecular Sciences"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:12:06Z","timestamp":1789949526000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD010461.pub4"}},"subtitle":[],"editor":[{"name":"Cochrane Central Editorial Service","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,6,2]]},"references-count":93,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2026,6]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd010461.pub4","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,2]]}}}