{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T10:09:41Z","timestamp":1781604581027,"version":"3.54.5"},"update-to":[{"DOI":"10.1002\/14651858.cd010520","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2017,2,20]],"date-time":"2017-02-20T00:00:00Z","timestamp":1487548800000}}],"reference-count":81,"publisher":"Wiley","issue":"2","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd010520.pub2","type":"journal-article","created":{"date-parts":[[2017,2,20]],"date-time":"2017-02-20T13:24:57Z","timestamp":1487597097000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Topical medication instillation techniques for glaucoma"],"prefix":"10.1002","volume":"2017","author":[{"given":"Li","family":"Xu","sequence":"first","affiliation":[{"name":"Hainan Eye Hospital, Zhongshan Ophthalmic Center; Hainan Provincial Key Laboratory of Ophthalmology; Haikou Hainan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuemei","family":"Wang","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health; Health Policy and Management; 624 N. Broadway St Baltimore Maryland USA 21205"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meijing","family":"Wu","sequence":"additional","affiliation":[{"name":"Feinberg School of Medicine, Northwestern University; Department of Neurological Surgery; 303 E Superior Street Chicago Illinois USA 60611"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,2,20]]},"reference":[{"issue":"6","key":"10.1002\/14651858.CD010520.pub2-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.ajo.2006.07.019","article-title":"Prevention of dermatologic side effects of bimatoprost 0.03% topical therapy","volume":"142","author":"Centofanti","year":"2006","journal-title":"American Journal of Ophthalmology"},{"issue":"2","key":"10.1002\/14651858.CD010520.pub2-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1136\/bjo.2010.198887","article-title":"Impact of eyelid closure on the intraocular pressure lowering effect of prostaglandins: a randomised controlled trial","volume":"96","author":"Maul","year":"2012","journal-title":"British Journal of Ophthalmology"},{"issue":"4","key":"10.1002\/14651858.CD010520.pub2-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/j.1600-0420.1996.tb00720.x","article-title":"The effects of nasolacrimal canal blockage on topical medications for glaucoma","volume":"74","author":"Ariturk","year":"1996","journal-title":"Acta Ophthalmologica"},{"issue":"11","key":"10.1002\/14651858.CD010520.pub2-BIB0004|cit4","first-page":"664","article-title":"Efficacy of silicone punctal plugs as adjuncts to topical pharmacotherapy of glaucoma - a pilot study","volume":"67","author":"Bartlett","year":"1996","journal-title":"Journal of the American Optometric Association"},{"issue":"7","key":"10.1002\/14651858.CD010520.pub2-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1111\/j.1755-3768.2012.02571.x","article-title":"Adherence improvement in Dutch glaucoma patients: a randomized controlled trial","volume":"91","author":"Beckers","year":"2013","journal-title":"Acta Ophthalmologica"},{"issue":"8","key":"10.1002\/14651858.CD010520.pub2-BIB0006|cit6","first-page":"810","article-title":"Alterations of intraocular pressure in comparison of self- and external-administered topical antiglaucomatosa during diurnal intraocular pressure measurements","volume":"231","author":"Bohm","year":"2014","journal-title":"Klinische Monatsblatter Fur Augenheilkunde"},{"issue":"1","key":"10.1002\/14651858.CD010520.pub2-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1755-3768.1979.tb06659.x","article-title":"Pilocarpine medication in open-angle glaucoma. A study using pilocarpine eyedrops and an ocular therapeutic system","volume":"57","author":"Brinchmann-Hansen","year":"1979","journal-title":"Acta Ophthalmologica"},{"issue":"1","key":"10.1002\/14651858.CD010520.pub2-BIB0008|cit8","first-page":"2","article-title":"Improper topical self-administration of ocular medication among patients with glaucoma","volume":"19","author":"Brown","year":"1984","journal-title":"Canadian Journal of Ophthalmology"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0009|cit9","first-page":"1096","article-title":"How glaucoma patients use their eye drops: potential effects of administration difficulties","volume":"135","author":"Smet","year":"2000","journal-title":"Pharmaceutisch Weekblad"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0010|cit10","first-page":"196","article-title":"Timolol 0.5% spray vs. timolol 0.5% drops for the control of intraocular pressure","author":"Doe","year":"1997","journal-title":"American Academy of Ophthalmology"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0011|cit11","first-page":"138","article-title":"The importance of eyelid closure and nasolacrimal occlusion following the ocular instillation of topical glaucoma medications, and the need for the universal inclusion of one of these techniques in all patient treatments and clinical studies","volume":"106","author":"Flach","year":"2008","journal-title":"Transactions of the American Ophthalmological Society"},{"issue":"9","key":"10.1002\/14651858.CD010520.pub2-BIB0012|cit12","first-page":"1199","article-title":"Drug delivery systems for topical ophthalmic medication","volume":"7","author":"Halberg","year":"1975","journal-title":"Annals of Ophthalmology"},{"issue":"2","key":"10.1002\/14651858.CD010520.pub2-BIB0013|cit13","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1159\/000307481","article-title":"Pump infusion of pilocarpine","volume":"171","author":"Harris","year":"1975","journal-title":"Ophthalmologica"},{"issue":"2","key":"10.1002\/14651858.CD010520.pub2-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0002-9394(89)90214-6","article-title":"Punctal occlusion and topical medications for glaucoma","volume":"107","author":"Huang","year":"1989","journal-title":"American Journal of Ophthalmology"},{"issue":"2","key":"10.1002\/14651858.CD010520.pub2-BIB0015|cit15","first-page":"128","article-title":"The effects of health education program using the health belief model on changing self care behaviors and treatment outcomes of primary glaucoma patients","volume":"17","author":"Moolasarn","year":"2007","journal-title":"Thai Journal of Hospital Pharmacy"},{"issue":"6","key":"10.1002\/14651858.CD010520.pub2-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1177\/112067210901900609","article-title":"Xal-Ease: impact of an ocular hypotensive delivery device on ease of eyedrop administration, patient compliance, and satisfaction","volume":"19","author":"Nordmann","year":"2009","journal-title":"European Journal of Ophthalmology"},{"issue":"12","key":"10.1002\/14651858.CD010520.pub2-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"2286","DOI":"10.1016\/j.ophtha.2009.05.026","article-title":"Interventions improve poor adherence with once daily glaucoma medications in electronically monitored patients","volume":"116","author":"Okeke","year":"2009","journal-title":"Ophthalmology"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0018|cit18","unstructured":"Opitz D Tung S Park J Jang U Silicone punctal plugs as an adjunctive therapy to travoprost 0.004% ophthalmic solution in primary open angle glaucoma and ocular hypertension American Academy of Optometry Annual Meeting; 2009 November 11-14: Orlando (FL) Orlando (FL) American Academy of Optometry 2009"},{"issue":"5","key":"10.1002\/14651858.CD010520.pub2-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1111\/j.1444-0938.2010.00587.x","article-title":"Silicone punctal plugs as an adjunctive therapy for open-angle glaucoma and ocular hypertension","volume":"94","author":"Opitz","year":"2011","journal-title":"Clinical and Experimental Optometry"},{"issue":"11","key":"10.1002\/14651858.CD010520.pub2-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1016\/S0161-6420(84)34141-0","article-title":"Plasma timolol in glaucoma patients","volume":"91","author":"Passo","year":"1984","journal-title":"Ophthalmology"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0021|cit21","unstructured":"Rotberg M Bosworth C Pleil AM Zhang M Paggiarino D Comparison of eyedrop delivery using either a novel horizontal delivery device or a conventional dropper bottle Investigative Ophthalmology and Visual Science 2006 ARVO E-abstract 456"},{"issue":"2","key":"10.1002\/14651858.CD010520.pub2-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"221","DOI":"10.5372\/1905-7415.0802.282","article-title":"The effect of the Thai \"Eye Drop Guide\" on success rate of eye drop self-instillation by glaucoma patients","volume":"8","author":"Sakiyalak","year":"2014","journal-title":"Asian Biomedicine"},{"issue":"2","key":"10.1002\/14651858.CD010520.pub2-BIB0023|cit23","first-page":"74","article-title":"Effect of nasolacrimal occlusion on dose and duration of action of tropical ocular hypotensive agents","volume":"10","author":"Sharir","year":"1993","journal-title":"Advances in Therapy"},{"issue":"2","key":"10.1002\/14651858.CD010520.pub2-BIB0024|cit24","first-page":"62","article-title":"Nasolacrimal occlusion improves the therapeutic index of antiglaucoma medications","volume":"5","author":"Sharir","year":"1994","journal-title":"Journal of the Association for Academic Minority Physicians"},{"issue":"1","key":"10.1002\/14651858.CD010520.pub2-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/S0002-9394(14)77405-7","article-title":"Therapeutic index of epinephrine and dipivefrin with nasolacrimal occlusion","volume":"114","author":"Zimmerman","year":"1992","journal-title":"American Journal of Ophthalmology"},{"issue":"1","key":"10.1002\/14651858.CD010520.pub2-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0002-9394(14)77404-5","article-title":"Therapeutic index of pilocarpine, carbachol, and timolol with nasolacrimal occlusion","volume":"114","author":"Zimmerman","year":"1992","journal-title":"American Journal of Ophthalmology"},{"issue":"4","key":"10.1002\/14651858.CD010520.pub2-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"e438","DOI":"10.1097\/IJG.0000000000000342","article-title":"Comparison of eye drop instillation before and after use of drop application strips in glaucoma patients on chronic topical therapy","volume":"25","author":"Sharma","year":"2016","journal-title":"Journal of Glaucoma"},{"issue":"3","key":"10.1002\/14651858.CD010520.pub2-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/S0149-2918(01)80048-5","article-title":"Efficacy and tolerability of timolol maleate ophthalmic gel-forming solution versus timolol ophthalmic solution in adults with open-angle glaucoma or ocular hypertension: a six-month, double-masked, multicenter study","volume":"23","author":"Shedden","year":"2001","journal-title":"Clinical Therapeutics"},{"issue":"9","key":"10.1002\/14651858.CD010520.pub2-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/0895-4356(88)90102-3","article-title":"Does lacrimal duct occlusion decrease intraocular pressure in patients refractory to medical treatment for glaucoma? A randomized, sham-controlled, crossover trial","volume":"41","author":"Simel","year":"1988","journal-title":"Journal of Clinical Epidemiology"},{"issue":"5","key":"10.1002\/14651858.CD010520.pub2-BIB0030|cit30","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1076\/ceyr.24.5.387.8516","article-title":"The safety and efficacy of timolol 0.5% in xanthan gum versus timolol gel forming solution 0.5%","volume":"24","author":"Stewart","year":"2002","journal-title":"Current Eye Research"},{"issue":"9","key":"10.1002\/14651858.CD010520.pub2-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1023\/A:1018938310628","article-title":"Controlled ocular timolol delivery: systemic absorption and intraocular pressure effects in humans","volume":"11","author":"Urtti","year":"1994","journal-title":"Pharmaceutical Research"},{"issue":"4","key":"10.1002\/14651858.CD010520.pub2-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1001\/archopht.1984.01040030429017","article-title":"Improving the therapeutic index of topically applied ocular drugs","volume":"102","author":"Zimmerman","year":"1984","journal-title":"Archives of Ophthalmology"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0033|cit33","unstructured":"NCT01417689 Eyedrop instillation technique: a randomized controlled trial clinicaltrials.gov\/ct2\/show\/NCT01417689"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0034|cit34","unstructured":"NCT01416415 Glaucoma eye drop instillation: impact of education clinicaltrials.gov\/ct2\/show\/NCT01416415"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0035|cit35","unstructured":"NCT02697318 Evaluation of a new method for instilling eye drops clinicaltrials.gov\/ct2\/show\/NCT02697318"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0036|cit36","unstructured":"American Academy of Ophthalmology (AAO) Preferred Practice Pattern Glaucoma Panel Primary Open-Angle Glaucoma PPP - 2015 www.aao.org\/preferred-practice-pattern\/primary-open-angle-glaucoma-ppp-2015"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0037|cit37","first-page":"5","article-title":"Primary angle-closure glaucoma: oculometry, epidemiology, and genetics in a high risk population","volume":"127","author":"Alsbirk","year":"1976","journal-title":"Acta Ophthalmologica Supplementum"},{"issue":"12","key":"10.1002\/14651858.CD010520.pub2-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1001\/archopht.1980.01020041015002","article-title":"Biostatistical analysis of the collaborative glaucoma study. I. Summary report of the risk factors for glaucomatous visual-field defects","volume":"98","author":"Armaly","year":"1980","journal-title":"Archives of Ophthalmology"},{"issue":"10","key":"10.1002\/14651858.CD010520.pub2-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1007\/s00417-008-0875-7","article-title":"Side effects of commonly used glaucoma medications: comparison of tolerability, chance of discontinuation, and patient satisfaction","volume":"246","author":"Beckers","year":"2008","journal-title":"Graefe's Archive for Clinical and Experimental Ophthalmology"},{"issue":"1","key":"10.1002\/14651858.CD010520.pub2-BIB0040|cit40","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S1350-9462(97)00002-5","article-title":"Ophthalmic drug delivery systems - recent advances","volume":"17","author":"Bourlais","year":"1998","journal-title":"Progress in Retinal and Eye Research"},{"issue":"2","key":"10.1002\/14651858.CD010520.pub2-BIB0041|cit41","first-page":"105","article-title":"Systemic side effects of glaucoma medications","volume":"82","author":"Cantor","year":"1989","journal-title":"Indiana Medicine"},{"issue":"4","key":"10.1002\/14651858.CD010520.pub2-BIB0042|cit42","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1442-9071.2012.02773.x","article-title":"Definition of glaucoma: clinical and experimental concepts","volume":"40","author":"Casson","year":"2012","journal-title":"Clinical and Experimental Ophthalmology"},{"issue":"1","key":"10.1002\/14651858.CD010520.pub2-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0014-4835(88)80093-9","article-title":"Relative effectiveness of prodrug and viscous solution approaches in maximizing the ratio of ocular to systemic absorption of topically applied timolol","volume":"46","author":"Chang","year":"1988","journal-title":"Experimental Eye Research"},{"issue":"6","key":"10.1002\/14651858.CD010520.pub2-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.survophthal.2008.08.006","article-title":"Risk factors for glaucoma onset and progression","volume":"53","author":"Coleman","year":"2008","journal-title":"Survey of Ophthalmology"},{"issue":"4","key":"10.1002\/14651858.CD010520.pub2-BIB0045|cit45","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1001\/archopht.122.4.477","article-title":"Causes and prevalence of visual impairment among adults in the United States","volume":"122","author":"Congdon","year":"2004","journal-title":"Archives of Ophthalmology"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0046|cit46","first-page":"103","article-title":"Ocular side effects of glaucoma treatment agents","volume":"304","author":"Ehongo","year":"2007","journal-title":"Bulletin de la Societe Belge d Ophtalmologie"},{"issue":"3","key":"10.1002\/14651858.CD010520.pub2-BIB0047|cit47","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/jps.2600810305","article-title":"Effect of nasolacrimal occlusion on timolol concentrations in the aqueous humor of the human eye","volume":"81","author":"Ellis","year":"1992","journal-title":"Journal of Pharmaceutical Sciences"},{"issue":"3","key":"10.1002\/14651858.CD010520.pub2-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.ophtha.2012.09.005","article-title":"An evidence-based review of prognostic factors for glaucomatous visual field progression","volume":"120","author":"Ernest","year":"2013","journal-title":"Ophthalmology"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0049|cit49","first-page":"457","article-title":"Extraocular fluid dynamics: how best to apply topical ocular medication","volume":"74","author":"Fraunfelder","year":"1976","journal-title":"Transactions of the American Ophthalmological Society"},{"issue":"9975","key":"10.1002\/14651858.CD010520.pub2-BIB0050|cit50","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/S0140-6736(14)62111-5","article-title":"Latanoprost for open-angle glaucoma (UKGTS): a randomised, multicentre, placebo-controlled trial","volume":"385","author":"Garway-Heath","year":"2015","journal-title":"Lancet"},{"issue":"2","key":"10.1002\/14651858.CD010520.pub2-BIB0051|cit51","first-page":"130","article-title":"How to identify randomized controlled trials in MEDLINE: ten years on","volume":"94","author":"Glanville","year":"2006","journal-title":"Journal of the Medical Library Association"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0052|cit52","unstructured":"GRADE Working Group, McMaster University GRADEpro GDT 2014"},{"issue":"3","key":"10.1002\/14651858.CD010520.pub2-BIB0053|cit53","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1097\/IJG.0b013e31820bd2e1","article-title":"Evaluating eye drop instillation technique in glaucoma patients","volume":"21","author":"Gupta","year":"2012","journal-title":"Journal of Glaucoma"},{"issue":"12","key":"10.1002\/14651858.CD010520.pub2-BIB0054|cit54","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1016\/j.ophtha.2009.06.042","article-title":"Natural history of open-angle glaucoma","volume":"116","author":"Heijl","year":"2009","journal-title":"Ophthalmology"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0055|cit55","unstructured":"Higgins JP Altman DG Sterne JAC Chapter 8: Assessing risk of bias in included studies. In: Higgins JP, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from handbook.cochrane.org"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0056|cit56","doi-asserted-by":"crossref","unstructured":"Ismail R Azuara-Blanco A Ramsay CR Consensus on outcome measures for glaucoma effectiveness trials: results from a Delphi and nominal group technique approaches Journal of Glaucoma 2016 539 46","DOI":"10.1097\/IJG.0000000000000301"},{"issue":"4","key":"10.1002\/14651858.CD010520.pub2-BIB0057|cit57","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1089\/jop.1986.2.365","article-title":"Effects of eyelid closure and nasolacrimal duct occlusion on the systemic absorption of ocular timolol in human subjects","volume":"2","author":"Kaila","year":"1986","journal-title":"Journal of Ocular Pharmacology"},{"issue":"4","key":"10.1002\/14651858.CD010520.pub2-BIB0058|cit58","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/S0002-9394(14)77926-7","article-title":"Side effects of topical ocular timolol","volume":"96","author":"Katz","year":"1983","journal-title":"American Journal of Ophthalmology"},{"issue":"4","key":"10.1002\/14651858.CD010520.pub2-BIB0059|cit59","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1046\/j.1442-9071.2002.00528.x","article-title":"Analysis of risk factors that may be associated with progression from ocular hypertension to primary open angle glaucoma","volume":"30","author":"Landers","year":"2002","journal-title":"Clinical and Experimental Ophthalmology"},{"issue":"9","key":"10.1002\/14651858.CD010520.pub2-BIB0060|cit60","doi-asserted-by":"crossref","first-page":"3783","DOI":"10.1167\/iovs.03-0077","article-title":"Risk factors associated with the incidence of open-angle glaucoma: the visual impairment project","volume":"44","author":"Le","year":"2003","journal-title":"Investigative Ophthalmology and Visual Science"},{"issue":"1","key":"10.1002\/14651858.CD010520.pub2-BIB0061|cit61","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1089\/jop.1986.2.67","article-title":"Topical ocular drug delivery: recent developments and future challenges","volume":"2","author":"Lee","year":"1986","journal-title":"Journal of Ocular Pharmacology"},{"issue":"7","key":"10.1002\/14651858.CD010520.pub2-BIB0062|cit62","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1093\/ajhp\/62.7.691","article-title":"Glaucoma and its treatment: a review","volume":"62","author":"Lee","year":"2005","journal-title":"American Journal of Health-System Pharmacy"},{"issue":"6","key":"10.1002\/14651858.CD010520.pub2-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1097\/00006324-198206000-00014","article-title":"Clinical implications of reported timolol-induced side effects","volume":"59","author":"Levine","year":"1982","journal-title":"American Journal of Optometry and Physiological Optics"},{"issue":"5","key":"10.1002\/14651858.CD010520.pub2-BIB0064|cit64","doi-asserted-by":"crossref","first-page":"367","DOI":"10.7326\/0003-4819-156-5-201203060-00009","article-title":"What comparative effectiveness research is needed? A framework for using guidelines and systematic reviews to identify evidence gaps and research priorities","volume":"156","author":"Li","year":"2012","journal-title":"Annals of Internal Medicine"},{"issue":"1","key":"10.1002\/14651858.CD010520.pub2-BIB0065|cit65","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2165\/00002512-200522010-00001","article-title":"Management of glaucoma: focus on pharmacological therapy","volume":"22","author":"Marquis","year":"2005","journal-title":"Drugs and Aging"},{"issue":"1 Suppl","key":"10.1002\/14651858.CD010520.pub2-BIB0066|cit66","first-page":"S20","article-title":"Current management of glaucoma and the need for complete therapy","volume":"14","author":"McKinnon","year":"2008","journal-title":"American Journal of Managed Care"},{"issue":"5","key":"10.1002\/14651858.CD010520.pub2-BIB0067|cit67","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/S0002-9394(03)00484-7","article-title":"Corneal thickness as a risk factor for visual field loss in patients with preperimetric glaucomatous optic neuropathy","volume":"136","author":"Medeiros","year":"2003","journal-title":"American Journal of Ophthalmology"},{"issue":"2","key":"10.1002\/14651858.CD010520.pub2-BIB0068|cit68","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2147\/tcrm.2006.2.2.193","article-title":"The management of glaucoma and intraocular hypertension: current approaches and recent advances","volume":"2","author":"Noecker","year":"2006","journal-title":"Therapeutics and Clinical Risk Management"},{"issue":"Suppl","key":"10.1002\/14651858.CD010520.pub2-BIB0069|cit69","first-page":"S19","article-title":"Natural history of glaucoma","volume":"59","author":"Pan","year":"2011","journal-title":"Indian Journal of Ophthalmology"},{"issue":"5","key":"10.1002\/14651858.CD010520.pub2-BIB0070|cit70","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1136\/bjo.80.5.389","article-title":"Number of people with glaucoma worldwide","volume":"80","author":"Quigley","year":"1996","journal-title":"British Journal of Ophthalmology"},{"issue":"3","key":"10.1002\/14651858.CD010520.pub2-BIB0071|cit71","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/bjo.2005.081224","article-title":"The number of people with glaucoma worldwide in 2010 and 2020","volume":"90","author":"Quigley","year":"2006","journal-title":"British Journal of Ophthalmology"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0072|cit72","unstructured":"Nordic Cochrane Centre, The Cochrane Collaboration Review Manager 5 (RevMan 5) 2014"},{"issue":"10","key":"10.1002\/14651858.CD010520.pub2-BIB0073|cit73","doi-asserted-by":"crossref","first-page":"e109400","DOI":"10.1371\/journal.pone.0109400","article-title":"Outcomes in Cochrane systematic reviews addressing four common eye conditions: an evaluation of completeness and comparability","volume":"9","author":"Saldanha","year":"2014","journal-title":"PLoS One"},{"issue":"2","key":"10.1002\/14651858.CD010520.pub2-BIB0074|cit74","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0039-6257(84)90168-1","article-title":"Ophthalmic drug delivery systems","volume":"29","author":"Shell","year":"1984","journal-title":"Survey of Ophthalmology"},{"issue":"12","key":"10.1002\/14651858.CD010520.pub2-BIB0075|cit75","doi-asserted-by":"crossref","first-page":"2398","DOI":"10.1016\/j.ophtha.2011.05.013","article-title":"The relationship between glaucoma medication adherence, eye drop technique, and visual field defect severity","volume":"118","author":"Sleath","year":"2011","journal-title":"Ophthalmology"},{"issue":"5","key":"10.1002\/14651858.CD010520.pub2-BIB0076|cit76","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.jaad.2011.06.005","article-title":"Eyelash growth in subjects treated with bimatoprost: a multicenter, randomized, double-masked, vehicle-controlled, parallel-group study","volume":"66","author":"Smith","year":"2012","journal-title":"Journal of the American Academy of Dermatology"},{"issue":"11","key":"10.1002\/14651858.CD010520.pub2-BIB0077|cit77","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","article-title":"Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis","volume":"121","author":"Tham","year":"2014","journal-title":"Ophthalmology"},{"key":"10.1002\/14651858.CD010520.pub2-BIB0078|cit78","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1146\/annurev.pu.17.050196.001005","article-title":"The epidemiology and control of open angle glaucoma: a population-based perspective","volume":"17","author":"Tielsch","year":"1996","journal-title":"Annual Review of Public Health"},{"issue":"6","key":"10.1002\/14651858.CD010520.pub2-BIB0079|cit79","first-page":"683","article-title":"Potential side effects of timolol therapy in the treatment of glaucoma","volume":"13","author":"Zimmerman","year":"1981","journal-title":"Annals of Ophthalmology"},{"issue":"Suppl","key":"10.1002\/14651858.CD010520.pub2-BIB0080|cit80","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/0039-6257(83)90142-X","article-title":"Facilitating patient compliance in glaucoma therapy","volume":"28","author":"Zimmerman","year":"1983","journal-title":"Survey of Ophthalmology"},{"issue":"5","key":"10.1002\/14651858.CD010520.pub2-BIB0081|cit81","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010520","article-title":"Topical medication instillation techniques for glaucoma","author":"Xu","year":"2013","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/14651858.CD010520.pub2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T03:17:20Z","timestamp":1704251840000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD010520.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Eyes and Vision Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,2,20]]},"references-count":81,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,2]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd010520.pub2","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,20]]}}}