{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:16:33Z","timestamp":1791314193445,"version":"4.3.1"},"update-to":[{"DOI":"10.1002\/14651858.cd010804","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2014,11,26]],"date-time":"2014-11-26T00:00:00Z","timestamp":1416960000000}}],"reference-count":71,"publisher":"Wiley","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd010804.pub2","type":"journal-article","created":{"date-parts":[[2014,11,26]],"date-time":"2014-11-26T02:02:11Z","timestamp":1416967331000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Exercise for cancer cachexia in adults"],"prefix":"10.1002","author":[{"given":"Antonio Jose","family":"Grande","sequence":"first","affiliation":[{"name":"Universidade do Extremo Sul Catarinense; Laboratory of Evidence-Based Practice; Av. Universit\u00e1ria, 1105 Predio S, LABEPI Criciuma Santa Catarina Brazil 88806-000"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valter","family":"Silva","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio Tiradentes (UNIT-AL); Department of Medicine; Macei\u00f3 AL Brazil 57038-000"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Riera","sequence":"additional","affiliation":[{"name":"Brazilian Cochrane Centre; Centro de Estudos em Medicina Baseada em Evid\u00eancias e Avalia\u00e7\u00e3o Tecnol\u00f3gica em Sa\u00fade; Rua Borges Lagoa, 564 cj 63 S\u00e3o Paulo SP Brazil 04038-000"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Medeiros","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo; Department of Bioscience; Av. Ana Costa, 95 Vila Mathias Santos S\u00e3o Paulo Brazil 11060-001"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone GP","family":"Vitoriano","sequence":"additional","affiliation":[{"name":"APS Santa Marcelina; Fontoura Xavier S\u00e3o Paulo S\u00e3o Paulo Brazil 09770-090"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria S","family":"Peccin","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo; Department of Human Movement Sciences; R. Silva Jardim, 136 - Vl. Mathias - Santos S\u00e3o Paulo Brazil 11015-020"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Maddocks","sequence":"additional","affiliation":[{"name":"Cicely Saunders Institute, King's College London; Department of Palliative Care, Policy and Rehabilitation; Denmark Hill London UK SE5 9PJ"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,11,26]]},"reference":[{"issue":"5","key":"10.1002\/14651858.CD010804.pub2-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1249\/01.MSS.0000384625.53502.5e","article-title":"Exercise and psychosocial interventions in breast cancer survivors: preliminary results of a randomized controlled trial","volume":"42","author":"Battaglini","year":"2010","journal-title":"Medicine and Science in Sports and Exercise"},{"issue":"1","key":"10.1002\/14651858.CD010804.pub2-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.ijrobp.2011.06.1954","article-title":"\"Pharyngocise\": randomized controlled trial of preventative exercises to maintain muscle structure and swallowing function during head-and-neck chemoradiotherapy","volume":"83","author":"Carnaby-Mann","year":"2012","journal-title":"International Journal of Radiation Oncology, Biology, Physics"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0003|cit3","first-page":"611","article-title":"Therapeutic exercise during out patient radiation therapy for advanced cancer: feasibility and impact on physical well-being","volume":"8","author":"Cheville","journal-title":"American Journal of Physical Medicine and Rehabilitation"},{"issue":"27","key":"10.1002\/14651858.CD010804.pub2-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"4605","DOI":"10.1200\/JCO.2008.20.0634","article-title":"Randomized controlled trial of the effects of aerobic exercise on physical functioning and quality of life in lymphoma patients","volume":"27","author":"Courneya","year":"2009","journal-title":"Journal of Clinical Oncology"},{"issue":"2","key":"10.1002\/14651858.CD010804.pub2-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s12185-009-0376-4","article-title":"Is physical exercise possible in patients with critical cytopenia undergoing intensive chemotherapy for acute leukaemia or aggressive lymphoma?","volume":"90","author":"Elter","year":"2009","journal-title":"International Journal of Hematology"},{"issue":"21","key":"10.1002\/14651858.CD010804.pub2-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"6379","DOI":"10.1158\/1078-0432.CCR-07-1147","article-title":"Daily physical-rest activities in relation to nutritional state, metabolism, and quality of life in cancer patients with progressive cachexia","volume":"13","author":"Fouladiun","year":"2007","journal-title":"Clinical Cancer Research"},{"issue":"8","key":"10.1002\/14651858.CD010804.pub2-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1038\/oby.2009.18","article-title":"Exercise improves body fat, lean mass, and bone mass in breast cancer survivors","volume":"17","author":"Irwin","year":"2009","journal-title":"Obesity (Silver Spring)"},{"issue":"4","key":"10.1002\/14651858.CD010804.pub2-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1249\/MSS.0000000000000158","article-title":"Exercise inpatients with non-small cell lung cancer","volume":"46","author":"Kuehr","year":"2014","journal-title":"Medicine and Science in Sports and Exercise"},{"issue":"12","key":"10.1002\/14651858.CD010804.pub2-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1016\/j.apmr.2013.06.008","article-title":"Differential effects of cardiovascular and resistance exercise on functional mobility in individuals with advanced cancer: a randomized trial","volume":"94","author":"Litterini","year":"2013","journal-title":"Archives of Physical Medicine and Rehabilitation"},{"issue":"4","key":"10.1002\/14651858.CD010804.pub2-BIB0010|cit10","first-page":"292","article-title":"Randomised phase III clinical trial of 5 different arms of treatment on 332 patients with cancer cachexia","volume":"14","author":"Mantovani","year":"2010","journal-title":"European Review for Medical and Pharmacological Sciences"},{"issue":"5","key":"10.1002\/14651858.CD010804.pub2-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.jpainsymman.2005.10.004","article-title":"The effect of a physical exercise program in palliative care: A phase II study","volume":"31","author":"Oldervoll","year":"2006","journal-title":"Journal of Pain and Symptom Management"},{"issue":"11","key":"10.1002\/14651858.CD010804.pub2-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1634\/theoncologist.2011-0133","article-title":"Physical exercise for cancer patients with advanced disease: a randomized controlled trial","volume":"16","author":"Oldervoll","year":"2011","journal-title":"Oncologist"},{"issue":"1","key":"10.1002\/14651858.CD010804.pub2-BIB0013|cit13","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.lungcan.2011.09.012","article-title":"Pre-cachexia in patients with stages I-III non-small cell lung cancer: systemic inflammation and functional impairment without activation of skeletal muscle ubiquitin proteasome system","volume":"76","author":"Op den Kamp","year":"2012","journal-title":"Lung Cancer"},{"issue":"5","key":"10.1002\/14651858.CD010804.pub2-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1007\/s00198-011-1761-4","article-title":"Effect of supervised and home exercise training on bone mineral density among breast cancer patients. A 12-month randomised controlled trial","volume":"23","author":"Saarto","year":"2012","journal-title":"Osteoporosis International"},{"issue":"3","key":"10.1002\/14651858.CD010804.pub2-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1188\/07.ONF.627-633","article-title":"Exercise effects on bone mineral density in women with breast cancer receiving adjuvant chemotherapy","volume":"34","author":"Schwartz","year":"2007","journal-title":"Oncology Nursing Forum"},{"issue":"31","key":"10.1002\/14651858.CD010804.pub2-BIB0016|cit16","first-page":"15","article-title":"Body composition in head and neck cancer patients undergoing concurrent chemoradiation","volume":"Suppl 1","author":"Zatarain","year":"2013","journal-title":"Journal of Clinical Oncology"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0017|cit17","unstructured":"ACTRN12611000870954 Anti-inflammatory and nutritional support, with simple exercises in lung cancer patients with weight loss https:\/\/www.anzctr.org.au\/Trial\/Registration\/TrialReview.aspx?id=343304"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1186\/1471-2407-11-493","article-title":"A randomised feasibility study of EPA and Cox-2 inhibitor (Celebrex) versus EPA, Cox-2 inhibitor (Celebrex), resistance training followed by ingestion of essential amino acids high in leucine in NSCLC cachectic patients--ACCeRT study","volume":"11","author":"Rogers","year":"2011","journal-title":"BMC Cancer"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0019|cit19","unstructured":"NCT01419145 A feasibility study of multimodal exercise\/nutrition\/anti-inflammatory treatment for cachexia - the Pre-MENAC study http:\/\/clinicaltrials.gov\/show\/NCT01419145"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1186\/1471-2407-12-446","article-title":"Exercise and nutrition for head and neck cancer patients: a patient oriented, clinic-supported randomized controlled trial","volume":"12","author":"Capozzi","year":"2012","journal-title":"BMC Cancer"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0021|cit21","unstructured":"NCT01681654 Exercise and Nutrition for Head and Neck Cancer Patients (ENHANCE) http:\/\/clinicaltrials.gov\/show\/NCT01681654"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0022|cit22","first-page":"2821","article-title":"Skeletal muscle density predicts prognosis in patients with metastatic renal cell carcinoma treated with targeted therapies","volume":"25","author":"Antoun","year":"2013","journal-title":"Cancer"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s13539-012-0067-5","article-title":"Are there any benefits of exercise training in cancer cachexia?","volume":"3","author":"Argil\u00e9s","year":"2012","journal-title":"Journal of Cachexia Sarcopenia and Muscle"},{"issue":"1","key":"10.1002\/14651858.CD010804.pub2-BIB0024|cit24","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004310.pub2","article-title":"Megestrol acetate for treatment of anorexia-cachexia syndrome","author":"Berenstein","year":"2005","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"S75","DOI":"10.1016\/j.bbi.2012.05.001","article-title":"Effects and potential mechanisms of exercise training on cancer progression: a translational perspective","volume":"30","author":"Betof","year":"2013","journal-title":"Brain, Behavior, and Immunity"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0026|cit26","unstructured":"Blum D Stene GB Solheim TS Fayers P Hjermstad MJ Baracos VE Euro-Impact Validation of the Consensus-Definition for Cancer Cachexia and evaluation of a classification model--a study based on data from an international multicentre project (EPCRC-CSA) Annals of Oncology"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0027|cit27","unstructured":"Deeks JJ Higgins JPT Altman DG Chapter 9: Analysing data and undertaking meta-analyses In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org"},{"issue":"1","key":"10.1002\/14651858.CD010804.pub2-BIB0028|cit28","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004597.pub2","article-title":"Eicosapentaenoic acid (EPA, an omega-3 fatty acid from fish oils) for the treatment of cancer cachexia","author":"Dewey","year":"2007","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1146\/annurev-med-061509-131248","article-title":"Muscle wasting in cancer cachexia: clinical implications, diagnosis, and emerging treatment strategies","volume":"62","author":"Dodson","year":"2011","journal-title":"Annual Review of Medicine"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0030|cit30","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.rmed.2011.11.002","article-title":"Factors influencing exercise performance in thoracic cancer","volume":"106","author":"England","year":"2012","journal-title":"Respiratory Medicine"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0031|cit31","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1016\/j.clnu.2008.06.013","article-title":"Cachexia: a new definition","volume":"27","author":"Evans","year":"2008","journal-title":"Clinical Nutrition"},{"issue":"8","key":"10.1002\/14651858.CD010804.pub2-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.ejca.2008.02.033","article-title":"Cancer cachexia: developing multimodal therapy for a multidimensional problem","volume":"44","author":"Fearon","year":"2008","journal-title":"European Journal of Cancer"},{"issue":"5","key":"10.1002\/14651858.CD010804.pub2-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S1470-2045(10)70218-7","article-title":"Definition and classification of cancer cachexia: an international consensus","volume":"12","author":"Fearon","year":"2011","journal-title":"Lancet Oncology"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.cmet.2012.06.011","article-title":"Cancer cachexia: mediators, signalling and metabolic pathways","volume":"16","author":"Fearon","year":"2012","journal-title":"Cell Metabolism"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0035|cit35","first-page":"607","article-title":"The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease","volume":"9","author":"Gleeson","journal-title":"Nature Reviews. Immunology"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1097\/MCO.0b013e32833f1ae5","article-title":"Resistance exercise and appropriate nutrition to counteract muscle wasting and promote muscle hypertrophy","volume":"13","author":"Glover","year":"2010","journal-title":"Current Opinion in Clinical Nutrition and Metabolic Care"},{"issue":"2","key":"10.1002\/14651858.CD010804.pub2-BIB0037|cit37","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1007\/s13539-012-0096-0","article-title":"Cancer cachexia prevention via physical exercise: molecular mechanisms","volume":"4","author":"Gould","year":"2013","journal-title":"Journal of Cachexia, Sarcopenia and Muscle"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Statistics in Medicine"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0040|cit40","unstructured":"Higgins JPT Deeks JJ Chapter 7: Selecting studies and collecting data In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0041|cit41","unstructured":"Higgins JPT Altman DG Chapter 8: Assessing risk of bias in included studies In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0042|cit42","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/j.lungcan.2011.10.009","article-title":"Prognostic significance of functional capacity and exercise behavior in patients with metastatic non-small cell lung cancer","volume":"76","author":"Jones","year":"2012","journal-title":"Lung Cancer"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/ncponc0112","article-title":"Therapy insight: cancer anorexia-cachexia syndrome--when all you can eat is yourself","volume":"2","author":"Laviano","year":"2005","journal-title":"Nature Clinical Practice Oncology"},{"issue":"2","key":"10.1002\/14651858.CD010804.pub2-BIB0044|cit44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/2044-5040-1-2","article-title":"Treating cancer cachexia to treat cancer","volume":"1","author":"Lee","year":"2011","journal-title":"Skeletal Muscle"},{"issue":"1","key":"10.1002\/14651858.CD010804.pub2-BIB0045|cit45","first-page":"37","article-title":"Physical activity as a supportive care intervention in palliative cancer patients: a systematic review","volume":"7","author":"Lowe","year":"2009","journal-title":"Journal of Supportive Oncology"},{"issue":"4","key":"10.1002\/14651858.CD010804.pub2-BIB0046|cit46","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1097\/SPC.0b013e32834bdde3","article-title":"Improving muscle mass and function in cachexia: non-drug approaches","volume":"5","author":"Maddocks","year":"2011","journal-title":"Current Opinion in Supportive and Palliative Care"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0047|cit47","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1615\/CritRevOncog.v17.i3.60","article-title":"Therapeutic exercise in cancer cachexia","volume":"17","author":"Maddocks","year":"2012","journal-title":"Critical Reviews in Oncogenesis"},{"issue":"15","key":"10.1002\/14651858.CD010804.pub2-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"9164","DOI":"10.1200\/jco.2010.28.15_suppl.9164","article-title":"Focus on the assessment of physical activity level of patients with cancer cachexia enrolled in a randomized phase III clinical trial","volume":"28","author":"Mantovani","year":"2010","journal-title":"Journal of Clinical Oncology, ASCO Annual Meeting Abstracts"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0049|cit49","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1152\/japplphysiol.00962.2010","article-title":"Mechanisms regulating muscle mass during disuse atrophy and rehabilitation in humans","volume":"110","author":"Marimuthu","year":"2011","journal-title":"Journal of Applied Physiology"},{"issue":"12","key":"10.1002\/14651858.CD010804.pub2-BIB0050|cit50","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1200\/JCO.2012.45.2722","article-title":"Cancer cachexia in the age of obesity: skeletal muscle depletion is a powerful prognostic factor, independent of body mass index","volume":"31","author":"Martin","year":"2013","journal-title":"Journal of Clinical Oncology"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0051|cit51","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.ctrv.2012.08.003","article-title":"The systemic inflammation-based Glasgow Prognostic Score: a decade of experience in patients with cancer","volume":"39","author":"McMillan","year":"2013","journal-title":"Cancer Treatment Reviews"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0052|cit52","first-page":"1091","article-title":"Pro-inflammatory cytokine release by peripheral blood mononuclear cells from patients with advanced pancreatic cancer: relationship to acute phase response and survival","volume":"21","author":"Moses","year":"2009","journal-title":"Oncology Reports"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0053|cit53","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.clnu.2009.12.004","article-title":"Consensus definition of sarcopenia, cachexia and pre-cachexia: Joint document elaborated by Specialist Interest Groups (SIG) \u2018cachexia -anorexia in chronic wasting diseases\u2019 and \u2018nutrition in genetics\u2019","volume":"29","author":"Muscaritoli","year":"2010","journal-title":"Clinical Nutrition"},{"issue":"1","key":"10.1002\/14651858.CD010804.pub2-BIB0054|cit54","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008427.pub2","article-title":"Interventions for fatigue and weight loss in adults with advanced progressive illness","author":"Payne","year":"2012","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0055|cit55","doi-asserted-by":"crossref","first-page":"3264","DOI":"10.1158\/1078-0432.CCR-06-3067","article-title":"Body composition as an independent determinant of 5-fluorouracil-based chemotherapy toxicity","volume":"13","author":"Prado","year":"2007","journal-title":"Clinical Cancer Research"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0056|cit56","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S1470-2045(08)70153-0","article-title":"Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study","volume":"9","author":"Prado","year":"2008","journal-title":"Lancet Oncology"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0057|cit57","doi-asserted-by":"crossref","first-page":"2920","DOI":"10.1158\/1078-0432.CCR-08-2242","article-title":"Sarcopenia as a determinant of chemotherapy toxicity and time to tumor progression in metastatic breast cancer patients receiving capecitabine treatment","volume":"15","author":"Prado","year":"2009","journal-title":"Clinical Cancer Research"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0058|cit58","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1038\/sj.bjc.6606087","article-title":"An inflammation-based prognostic score (mGPS) predicts cancer survival independent of tumour site: a Glasgow Inflammation Outcome Study","volume":"104","author":"Proctor","year":"2011","journal-title":"British Journal of Cancer"},{"issue":"4","key":"10.1002\/14651858.CD010804.pub2-BIB0059|cit59","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008664.pub2","article-title":"Thalidomide for managing cancer cachexia","author":"Reid","year":"2012","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0060|cit60","unstructured":"The Nordic Cochrane Centre, The Cochrane Collaboration Review Manager (RevMan) 2012"},{"issue":"4","key":"10.1002\/14651858.CD010804.pub2-BIB0061|cit61","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1097\/SPC.0b013e328359b668","article-title":"Evidence base for multimodal therapy in cachexia","volume":"6","author":"Solheim","year":"2012","journal-title":"Current Opinion in Supportive and Palliative Care"},{"issue":"2","key":"10.1002\/14651858.CD010804.pub2-BIB0062|cit62","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1365-2354.2010.01214.x","article-title":"Colorectal cancer survivors' exercise experiences and preferences: qualitative findings from an exercise rehabilitation programme immediately after chemotherapy","volume":"20","author":"Spence","year":"2011","journal-title":"European Journal of Cancer Care (English Language Edition)"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1096\/fj.02-0670fje","article-title":"Exercise and IL-6 infusion inhibit endotoxin-induced TNF\u03b1 production in humans","volume":"17","author":"Starkie","year":"2003","journal-title":"FASEB Journal"},{"issue":"3","key":"10.1002\/14651858.CD010804.pub2-BIB0064|cit64","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/j.critrevonc.2013.07.001","article-title":"Effect of physical exercise on muscle mass and strength in cancer patients during treatment--a systematic review","volume":"88","author":"Stene","year":"2013","journal-title":"Critical Reviews in Oncology\/Hematology"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0065|cit65","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.clnu.2011.12.008","article-title":"Sexual dimorphism modulates the impact of cancer cachexia on lower limb muscle mass and function","volume":"31","author":"Stephens","year":"2012","journal-title":"Clinical Nutrition"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0066|cit66","volume-title":"ACSM's Guidelines for Exercise Testing and Prescription","author":"Thompson","year":"2010"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0067|cit67","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1152\/physrev.00016.2008","article-title":"Mechanisms of cancer cachexia","volume":"89","author":"Tisdale","year":"2009","journal-title":"Physiology Review"},{"issue":"9","key":"10.1002\/14651858.CD010804.pub2-BIB0068|cit68","doi-asserted-by":"crossref","first-page":"4160","DOI":"10.1210\/en.2006-0251","article-title":"Insulin resistance accelerates muscle protein degradation: activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling","volume":"147","author":"Wang","year":"2006","journal-title":"Endocrinology"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0069|cit69","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1080\/02841860802130001","article-title":"Morphology, metabolism, microcirculation, and strength of skeletal muscles in cancer-related cachexia","volume":"48","author":"Weber","year":"2009","journal-title":"Acta Oncologica"},{"key":"10.1002\/14651858.CD010804.pub2-BIB0070|cit70","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1136\/thx.2007.084665","article-title":"Symptoms limiting activity in cancer patients with breathlessness on exertion: ask about muscle fatigue","volume":"63","author":"Wilcock","year":"2008","journal-title":"Thorax"},{"issue":"10","key":"10.1002\/14651858.CD010804.pub2-BIB0071|cit71","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010804","article-title":"Exercise for cancer cachexia in adults","author":"Grande","year":"2013","journal-title":"Cochrane Database of Systematic Reviews"}],"updated-by":[{"DOI":"10.1002\/14651858.cd010804.pub3","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T00:00:00Z","timestamp":1616025600000}}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/14651858.CD010804.pub2\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T22:48:41Z","timestamp":1628549321000},"score":1,"resource":{"primary":{"URL":"https:\/\/doi.wiley.com\/10.1002\/14651858.CD010804.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Pain, Palliative and Supportive Care Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,11,26]]},"references-count":71,"URL":"https:\/\/doi.org\/10.1002\/14651858.cd010804.pub2","relation":{"new_version":[{"id-type":"doi","id":"10.1002\/14651858.CD010804.pub3","asserted-by":"object"}]},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,26]]}}}