{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:45:41Z","timestamp":1791765941996,"version":"4.3.4"},"update-to":[{"DOI":"10.1002\/14651858.cd011506.pub2","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000}}],"reference-count":112,"publisher":"Wiley","issue":"1","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd011506.pub3","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T14:36:41Z","timestamp":1767796601000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cerebral near-infrared spectroscopy monitoring for prevention of death or neurodevelopmental disability in very preterm infants"],"prefix":"10.1002","volume":"2026","author":[{"given":"Enrico","family":"Bodrero","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit; S. Croce e Carle Hospital; Cuneo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Carolina","family":"Isaza-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Materno Perinatal Care; Bolivarana University Clinic; Medellin Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Fiander","sequence":"additional","affiliation":[{"name":"Cochrane Neonatal Group; Halifax Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gorm","family":"Greisen","sequence":"additional","affiliation":[{"name":"Department of Neonatology; Copenhagen University Hospital - Rigshospitalet; Copenhagen Denmark"},{"name":"Institute of Clinical Medicine; University of Copenhagen; Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Gluud","sequence":"additional","affiliation":[{"name":"Cochrane Hepato-Biliary Group, The Copenhagen Trial Unit, Centre for Clinical Intervention Research; The Capital Region, Copenhagen University Hospital - Rigshospitalet; Copenhagen Denmark"},{"name":"The Department of Regional Health Research; The Faculty of Health Sciences, University of Southern Denmark; Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4775-872X","authenticated-orcid":false,"given":"Matteo","family":"Bruschettini","sequence":"additional","affiliation":[{"name":"Cochrane Sweden, Department of Research, Development, Education and Innovation; Sk\u00e5ne University Hospital; Lund Sweden"},{"name":"Paediatrics, Department of Clinical Sciences Lund; Lund University; Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"supported by Cochrane Sweden and Cochrane Neonatal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,7]]},"reference":[{"issue":"6","key":"10.1002\/14651858.CD011506.pub3-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"e2022057442","DOI":"10.1542\/peds.2022-057442","article-title":"Preterm brain injury and neurodevelopmental outcomes: a meta-analysis","volume":"150","author":"Rees","year":"2022","journal-title":"Pediatrics"},{"issue":"8","key":"10.1002\/14651858.CD011506.pub3-BIB0002|cit2","doi-asserted-by":"publisher","first-page":"e209264","DOI":"10.1212\/WNL.0000000000209264","article-title":"Size and location of preterm brain injury and associations with neurodevelopmental outcomes","volume":"102","author":"Selvanathan","year":"2024","journal-title":"Neurology"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0003|cit3","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/S1474-4422(08)70294-1","article-title":"Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances","volume":"8","author":"Volpe","year":"2009","journal-title":"Lancet Neurology"},{"issue":"2","key":"10.1002\/14651858.CD011506.pub3-BIB0004|cit4","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1053\/siny.2001.0047","article-title":"Intraventricular haemorrhage and posthaemorrhagic hydrocephalus: pathogenesis, prevention and future interventions","volume":"6","author":"Whitelaw","year":"2001","journal-title":"Seminars in Neonatology"},{"issue":"2","key":"10.1002\/14651858.CD011506.pub3-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/s41390-021-01483-w","article-title":"Cerebral oxygen saturation and autoregulation during hypotension in extremely preterm infants","volume":"90","author":"Thewissen","year":"2021","journal-title":"Pediatric Research"},{"issue":"6","key":"10.1002\/14651858.CD011506.pub3-BIB0006|cit6","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1542\/peds.2004-1073","article-title":"Hypotensive extremely low birth weight infants have reduced cerebral blood flow","volume":"114","author":"Munro","year":"2004","journal-title":"Pediatrics"},{"issue":"5","key":"10.1002\/14651858.CD011506.pub3-BIB0007|cit7","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1203\/PDR.0b013e3181f2bd4d","article-title":"Changes in cerebral perfusion in extremely LBW infants during the first 72 h after birth","volume":"68","author":"Takami","year":"2010","journal-title":"Pediatric Research"},{"issue":"11","key":"10.1002\/14651858.CD011506.pub3-BIB0008|cit8","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1038\/sj.jp.7211608","article-title":"Avoiding hyperoxia in infants \u22641250 g is associated with improved short- and long-term outcomes","volume":"26","author":"Deulofeut","year":"2006","journal-title":"Journal of Perinatology"},{"issue":"12","key":"10.1002\/14651858.CD011506.pub3-BIB0009|cit9","doi-asserted-by":"publisher","first-page":"2901","DOI":"10.1161\/STROKEAHA.110.597229","article-title":"Cerebral oxygenation in preterm infants with germinal matrix-intraventricular hemorrhages","volume":"41","author":"Verhagen","year":"2010","journal-title":"Stroke"},{"issue":"3","key":"10.1002\/14651858.CD011506.pub3-BIB0010|cit10","doi-asserted-by":"publisher","first-page":"228","DOI":"10.3340\/jkns.2022.0288","article-title":"Intraventricular hemorrhage (IVH) and posthemorrhagic hydrocephalus (PHH) in preterm infants","volume":"66","author":"Tsao","year":"2023","journal-title":"Journal of Korean Neurosurgical Society"},{"issue":"2","key":"10.1002\/14651858.CD011506.pub3-BIB0011|cit11","doi-asserted-by":"publisher","first-page":"F153","DOI":"10.1136\/adc.2006.108837","article-title":"Pathogenesis of cerebral white matter injury of prematurity","volume":"93","author":"Khwaja","year":"2008","journal-title":"Archives of Disease in Childhood. Fetal and Neonatal Edition"},{"issue":"4","key":"10.1002\/14651858.CD011506.pub3-BIB0012|cit12","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1159\/000180113","article-title":"Early treated hypotension and outcome in very low birth weight infants","volume":"95","author":"Kuint","year":"2009","journal-title":"Neonatology"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0013|cit13","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/s12974-025-03389-4","article-title":"Prenatal inflammation exacerbates hyperoxia-induced neonatal brain injury","volume":"22","author":"Serdar","year":"2025","journal-title":"Journal of Neuroinflammation"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0014|cit14","doi-asserted-by":"publisher","first-page":"2497058","DOI":"10.1080\/14767058.2025.2497058","article-title":"Risk factors for retinopathy of prematurity among preterm infants with bronchopulmonary dysplasia","volume":"38","author":"Zhang","year":"2025","journal-title":"Journal of Maternal-Fetal & Neonatal Medicine"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0015|cit15","doi-asserted-by":"publisher","first-page":"s41390","DOI":"10.1038\/s41390-025-03986-2","article-title":"Neonatal encephalopathy and hypoxic-ischemic encephalopathy: the state of the art","volume":"Epub ahead of p","author":"Chakkarapani","year":"2025","journal-title":"Pediatric Research"},{"issue":"6","key":"10.1002\/14651858.CD011506.pub3-BIB0016|cit16","doi-asserted-by":"publisher","first-page":"e2417431","DOI":"10.1001\/jamanetworkopen.2024.17431","article-title":"Clinical practice guideline for red blood cell transfusion thresholds in very preterm neonates","volume":"7","author":"Deschmann","year":"2024","journal-title":"JAMA Network Open"},{"issue":"4","key":"10.1002\/14651858.CD011506.pub3-BIB0017|cit17","doi-asserted-by":"publisher","first-page":"F346","DOI":"10.1136\/archdischild-2015-309639","article-title":"Management and investigation of neonatal encephalopathy: 2017 update","volume":"102","author":"Martinello","year":"2017","journal-title":"Archives of Disease in Childhood. Fetal and Neonatal Edition"},{"issue":"5","key":"10.1002\/14651858.CD011506.pub3-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1097\/ACO.0b013e32833e1536","article-title":"Noninvasive cerebral oximetry: is there light at the end of the tunnel?","volume":"23","author":"Highton","year":"2010","journal-title":"Current Opinion in Anaesthesiology"},{"issue":"4","key":"10.1002\/14651858.CD011506.pub3-BIB0019|cit19","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1016\/j.clp.2009.07.007","article-title":"Advances in near-infrared spectroscopy to study the brain of the preterm and term neonate","volume":"36","author":"Wolf","year":"2009","journal-title":"Clinics in Perinatology"},{"issue":"4","key":"10.1002\/14651858.CD011506.pub3-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1097\/00000542-200010000-00012","article-title":"Arterial and venous contributions to near-infrared cerebral oximetry","volume":"93","author":"Watzman","year":"2000","journal-title":"Anesthesiology"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1365-2044.1998.00263.x","article-title":"A comparison of near-infrared spectroscopy and jugular bulb oximetry in comatose patients resuscitated from a cardiac arrest","volume":"53","author":"Buunk","year":"1998","journal-title":"Anaesthesia"},{"issue":"6","key":"10.1002\/14651858.CD011506.pub3-BIB0022|cit22","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1007\/s00134-005-2618-0","article-title":"Comparison between cerebral tissue oxygenation index measured by near-infrared spectroscopy and venous jugular bulb saturation in children","volume":"31","author":"Nagdyman","year":"2005","journal-title":"Intensive Care Medicine"},{"issue":"10","key":"10.1002\/14651858.CD011506.pub3-BIB0023|cit23","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.1088\/0967-3334\/28\/10\/010","article-title":"Research on the relationship between brain anoxia at different regional oxygen saturations and brain damage using near-infrared spectroscopy","volume":"28","author":"Hou","year":"2007","journal-title":"Physiological Measurement"},{"issue":"3","key":"10.1002\/14651858.CD011506.pub3-BIB0024|cit24","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1097\/00004647-200203000-00011","article-title":"Near-infrared spectroscopy cerebral oxygen saturation thresholds for hypoxia-ischemia in piglets","volume":"22","author":"Kurth","year":"2002","journal-title":"Journal of Cerebral Blood Flow and Metabolism"},{"issue":"4","key":"10.1002\/14651858.CD011506.pub3-BIB0025|cit25","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1213\/ane.0b013e318196ac8e","article-title":"Cerebral oxygen saturation-time threshold for hypoxic-ischemic injury in piglets","volume":"108","author":"Kurth","year":"2009","journal-title":"Anesthesia and Analgesia"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0026|cit26","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1097\/ALN.0b013e3181fef34e","article-title":"Preoperative cerebral oxygen saturation and clinical outcomes in cardiac surgery","volume":"114","author":"Heringlake","year":"2011","journal-title":"Anesthesiology"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0027|cit27","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1053\/j.jvca.2010.03.019","article-title":"The relationship between cerebral oxygen saturation changes and postoperative cognitive dysfunction in elderly patients after coronary artery bypass graft surgery","volume":"25","author":"Tournay-Jett\u00e9","year":"2011","journal-title":"Journal of Cardiothoracic and Vascular Anesthesia"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0028|cit28","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.athoracsur.2008.08.070","article-title":"Cerebral oxygen desaturation predicts cognitive decline and longer hospital stay after cardiac surgery","volume":"87","author":"Slater","year":"2009","journal-title":"Annals of Thoracic Surgery"},{"issue":"2","key":"10.1002\/14651858.CD011506.pub3-BIB0029|cit29","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1542\/peds.2005-0987","article-title":"Cerebral oxygenation and electrical activity after birth asphyxia: their relation to outcome","volume":"117","author":"Toet","year":"2006","journal-title":"Pediatrics"},{"issue":"5","key":"10.1002\/14651858.CD011506.pub3-BIB0030|cit30","doi-asserted-by":"publisher","first-page":"054005","DOI":"10.1117\/1.2357730","article-title":"Precision of measurement of cerebral tissue oxygenation index using near-infrared spectroscopy in preterm neonates","volume":"11","author":"Sorensen","year":"2006","journal-title":"Journal of Biomedical Optics"},{"issue":"3","key":"10.1002\/14651858.CD011506.pub3-BIB0031|cit31","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/j.jpeds.2013.10.041","article-title":"Early cerebral oxygen extraction and the risk of death or sonographic brain injury in very preterm infants","volume":"164","author":"Balegar","year":"2014","journal-title":"Journal of Pediatrics"},{"issue":"5","key":"10.1002\/14651858.CD011506.pub3-BIB0032|cit32","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1016\/j.jpeds.2013.12.042","article-title":"Hypotension in preterm neonates: low blood pressure alone does not affect neurodevelopmental outcome","volume":"164","author":"Alderliesten","year":"2014","journal-title":"Journal of Pediatrics"},{"issue":"4","key":"10.1002\/14651858.CD011506.pub3-BIB0033|cit33","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1177\/1089253207311685","article-title":"A proposed algorithm for the intraoperative use of cerebral near-infrared spectroscopy","volume":"11","author":"Denault","year":"2007","journal-title":"Seminars in Cardiothoracic and Vascular Anesthesia"},{"issue":"21","key":"10.1002\/14651858.CD011506.pub3-BIB0034|cit34","doi-asserted-by":"publisher","first-page":"1970","DOI":"10.1056\/NEJMoa091178","article-title":"Early CPAP versus surfactant in extremely preterm infants","volume":"362","author":"Finer","year":"2010","journal-title":"New England Journal of Medicine"},{"issue":"11","key":"10.1002\/14651858.CD011506.pub3-BIB0035|cit35","doi-asserted-by":"publisher","first-page":"3047","DOI":"10.1364\/BOE.2.003047","article-title":"Tissue oximetry: a comparison of mean values of regional tissue saturation, reproducibility and dynamic range of four NIRS-instruments on the human forearm","volume":"2","author":"Hyttel-Sorensen","year":"2011","journal-title":"Biomedical Optics Express"},{"issue":"5","key":"10.1002\/14651858.CD011506.pub3-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1046\/j.1460-9592.2003.01111.x","article-title":"Measurement of cerebral oxygenation state in anaesthetized children using the INVOS 5100 cerebral oximeter","volume":"13","author":"Dullenkopf","year":"2003","journal-title":"Pediatric Anesthesia"},{"issue":"5","key":"10.1002\/14651858.CD011506.pub3-BIB0037|cit37","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1111\/apa.12567","article-title":"Cerebral oxygenation after birth - a comparison of INVOS \u00aeand FORE-SIGHT\u2122 near-infrared spectroscopy oximeters","volume":"103","author":"Hessel","year":"2014","journal-title":"Acta Paediatrica"},{"issue":"7","key":"10.1002\/14651858.CD011506.pub3-BIB0038|cit38","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.1038\/s41390-020-0752-6","article-title":"Comparison of INVOS 5100C and Nonin SenSmart X-100 oximeter performance in preterm infants with spontaneous apnea","volume":"87","author":"Andresen","year":"2020","journal-title":"Pediatric Research"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0039|cit39","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.jpeds.2015.11.053","article-title":"Cerebral oxygen saturation to guide oxygen delivery in preterm neonates for the immediate transition after birth: a 2-center randomized controlled pilot feasibility trial","volume":"170","author":"Pichler","year":"2016","journal-title":"Journal of Pediatrics"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0040|cit40","doi-asserted-by":"publisher","first-page":"g7635","DOI":"10.1136\/bmj.g7635","article-title":"Cerebral near infrared spectroscopy oximetry in extremely preterm infants: phase II randomised clinical trial","volume":"350","author":"Hyttel-Sorensen","year":"2015","journal-title":"BMJ (Online)"},{"issue":"4","key":"10.1002\/14651858.CD011506.pub3-BIB0041|cit41","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1097\/ALN.0000000000001029","article-title":"Cerebral oximetry monitoring to maintain normal cerebral oxygen saturation during high-risk cardiac surgery: a randomized controlled feasibility trial","volume":"124","author":"Deschamps","year":"2016","journal-title":"Anesthesiology"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0042|cit42","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1213\/01.ane.0000246814.29362.f4","article-title":"Monitoring brain oxygen saturation during coronary bypass surgery: a randomized, prospective study","volume":"104","author":"Murkin","year":"2007","journal-title":"Anesthesia and Analgesia"},{"issue":"3","key":"10.1002\/14651858.CD011506.pub3-BIB0043|cit43","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1213\/01.ane.0000166974.96219.cd","article-title":"Continuous monitoring of cerebral oxygen saturation in elderly patients undergoing major abdominal surgery minimizes brain exposure to potential hypoxia","volume":"101","author":"Casati","year":"2005","journal-title":"Anesthesia and Analgesia"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"F15","DOI":"10.1136\/fn.81.1.F15","article-title":"Low cerebral blood flow is a risk factor for severe intraventricular haemorrhage","volume":"81","author":"Meek","year":"1999","journal-title":"Archives of Disease in Childhood. Fetal and Neonatal Edition"},{"issue":"8","key":"10.1002\/14651858.CD011506.pub3-BIB0045|cit45","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1001\/archpedi.154.8.822","article-title":"Surveillance protocol for the detection of intracranial abnormalities in premature neonates","volume":"154","author":"Perlman","year":"2000","journal-title":"Archives of Pediatrics & Adolescent Medicine"},{"issue":"1955","key":"10.1002\/14651858.CD011506.pub3-BIB0046|cit46","doi-asserted-by":"publisher","first-page":"4440","DOI":"10.1098\/rsta.2011.0261","article-title":"Has the time come to use near-infrared spectroscopy as a routine clinical tool in preterm infants undergoing intensive care?","volume":"369","author":"Greisen","year":"2011","journal-title":"Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences"},{"issue":"17","key":"10.1002\/14651858.CD011506.pub3-BIB0047|cit47","doi-asserted-by":"publisher","first-page":"1680","DOI":"10.1056\/NEJMc1101319","article-title":"Increased 36-week survival with high oxygen saturation target in extremely preterm infants","volume":"364","author":"Stenson","year":"2011","journal-title":"New England Journal of Medicine"},{"issue":"7515","key":"10.1002\/14651858.CD011506.pub3-BIB0048|cit48","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1136\/bmj.331.7515.507","article-title":"Analysis of quality of interventions in systematic reviews","volume":"331","author":"Herbert","year":"2005","journal-title":"BMJ (Clinical Research Ed.)"},{"issue":"4","key":"10.1002\/14651858.CD011506.pub3-BIB0049|cit49","doi-asserted-by":"crossref","first-page":"295","DOI":"10.7326\/0003-4819-148-4-200802190-00008","article-title":"Extending the CONSORT statement to randomized trials of nonpharmacologic treatment: explanation and elaboration","volume":"148","author":"Boutron","year":"2008","journal-title":"Annals of Internal Medicine"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0050|cit50","first-page":"A4533","article-title":"Clinical use of cerebral oximetry in extremely preterm infants is feasible","volume":"60","author":"Hyttel-Sorensen","year":"2013","journal-title":"Danish Medical Journal"},{"issue":"3","key":"10.1002\/14651858.CD011506.pub3-BIB0051|cit51","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1159\/000351346","article-title":"The SafeBoosC Phase II randomised clinical trial: a treatment guideline for targeted near-infrared-derived cerebral tissue oxygenation versus standard treatment in extremely preterm infants","volume":"104","author":"Pellicer","year":"2013","journal-title":"Neonatology"},{"issue":"9","key":"10.1002\/14651858.CD011506.pub3-BIB0052|cit52","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD011506.pub2","article-title":"Cerebral near-infrared spectroscopy monitoring for prevention of brain injury in very preterm infants","author":"Hyttel-Sorensen","year":"2017","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0053|cit53","unstructured":"Higgins JP Thomas J Chandler J Cumpston M Li T Page MJ Cochrane Handbook for Systematic Reviews of Interventions Version 6.5 (updated August 2024). Cochrane, 2024 Available from https:\/\/www.cochrane.org\/authors\/handbooks-and-manuals\/handbook"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0054|cit54","unstructured":"Higgins JP Lasserson T Thomas J Flemyng E Churchill R Methodological expectations of Cochrane intervention reviews . Cochrane: London, Version August 2023 https:\/\/www.cochrane.org\/authors\/handbooks-and-manuals\/mecir-manual"},{"issue":"3","key":"10.1002\/14651858.CD011506.pub3-BIB0055|cit55","doi-asserted-by":"crossref","first-page":"e1003583","DOI":"10.1371\/journal.pmed.1003583","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"18","author":"Page","year":"2021","journal-title":"PLoS Medicine"},{"issue":"372","key":"10.1002\/14651858.CD011506.pub3-BIB0056|cit56","doi-asserted-by":"publisher","first-page":"n160","DOI":"10.1136\/bmj.n160","article-title":"PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews","volume":"29","author":"Page","year":"2021","journal-title":"BMJ (Clinical Research Ed.)"},{"issue":"2","key":"10.1002\/14651858.CD011506.pub3-BIB0057|cit57","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD011506","article-title":"Cerebral near-infrared spectroscopy monitoring for prevention of brain injury in very preterm infants","author":"Hyttel-Sorensen","year":"2015","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0058|cit58","unstructured":"McKenzie JE Brennan SE Ryan RE Thomson HJ Johnston RV Thomas J Chapter 3: Defining the criteria for including studies and how they will be grouped for the synthesis (chapter last updated August 2023). In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, et al, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 6.5. Cochrane, 2024 Available from https:\/\/www.cochrane.org\/authors\/handbooks-and-manuals\/handbook"},{"issue":"6","key":"10.1002\/14651858.CD011506.pub3-BIB0059|cit59","doi-asserted-by":"publisher","first-page":"e1000289","DOI":"10.1371\/journal.pmed.1000289","article-title":"Gestational age at delivery and special educational need: retrospective cohort study of 407,503 schoolchildren","volume":"7","author":"MacKay","year":"2010","journal-title":"PLoS Medicine"},{"issue":"11","key":"10.1002\/14651858.CD011506.pub3-BIB0060|cit60","doi-asserted-by":"publisher","first-page":"e24727\u201312","DOI":"10.1371\/journal.pone.0024727","article-title":"Gestational age patterns of fetal and neonatal mortality in Europe: results from the Euro-Peristat Project","volume":"6","author":"Mohangoo","year":"2011","journal-title":"PloS One"},{"issue":"4","key":"10.1002\/14651858.CD011506.pub3-BIB0061|cit61","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1111\/j.1469-8749.2011.04216.x","article-title":"Brain development of very preterm and very low-birthweight children in childhood and adolescence: a meta-analysis","volume":"54","author":"Kieviet","year":"2012","journal-title":"Developmental Medicine and Child Neurology"},{"issue":"5","key":"10.1002\/14651858.CD011506.pub3-BIB0062|cit62","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1056\/NEJMra2303347","article-title":"Defining the neurologic consequences of preterm birth","volume":"389","author":"Inder","year":"2023","journal-title":"New England Journal of Medicine"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD011506.pub3-BIB0063|cit63","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1038\/s41390-020-0781-1","article-title":"Preterm white matter injury: ultrasound diagnosis and classification","volume":"87","author":"Agut","year":"2020","journal-title":"Pediatric Research"},{"issue":"11","key":"10.1002\/14651858.CD011506.pub3-BIB0064|cit64","doi-asserted-by":"publisher","first-page":"2208","DOI":"10.3174\/ajnr.A3521","article-title":"New MR imaging assessment tool to define brain abnormalities in very preterm infants at term","volume":"34","author":"Kidokoro","year":"2013","journal-title":"American Journal of Neuroradiology"},{"issue":"4","key":"10.1002\/14651858.CD011506.pub3-BIB0065|cit65","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0022-3476(78)80282-0","article-title":"Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm","volume":"92","author":"Papile","year":"1978","journal-title":"Journal of Pediatrics"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0066|cit66","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00000658-197801000-00001","article-title":"Neonatal necrotizing enterocolitis. Therapeutic decisions based upon clinical staging","volume":"187","author":"Bell","year":"1978","journal-title":"Annals of Surgery"},{"issue":"7","key":"10.1002\/14651858.CD011506.pub3-BIB0067|cit67","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1001\/archopht.123.7.991","article-title":"The international classification of retinopathy of prematurity revisited","volume":"123","author":"International Committee for the Classification of Retinopathy of Prematurity","year":"2005","journal-title":"Archives of Ophthalmology"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0068|cit68","unstructured":"Covidence Veritas Health Innovation 2024"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0069|cit69","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.jpeds.2015.11.053","article-title":"Cerebral oxygen saturation to guide oxygen delivery in preterm neonates for the immediate transition after birth: a 2-center randomized controlled pilot feasibility trial","volume":"170","author":"Pichler","year":"2016","journal-title":"Journal of Pediatrics"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0070|cit70","unstructured":"Cerebral oxygenation to guide supplemental oxygen (COSGOD) https:\/\/clinicaltrials.gov\/study\/NCT02017691"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0071|cit71","doi-asserted-by":"publisher","first-page":"15","DOI":"10.3389\/fped.2018.00015","article-title":"Avoiding arterial hypotension in preterm neonates (AHIP). A single center randomised controlled study investigating simultaneous near infrared spectroscopy measurements of cerebral and peripheral regional tissue oxygenation and dedicated interventions","volume":"6","author":"Pichler","year":"2018","journal-title":"Frontiers in Pediatrics"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0072|cit72","unstructured":"Avoiding hypotension in preterm neonates https:\/\/clinicaltrials.gov\/show\/NCT01910467"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0073|cit73","unstructured":"Review Manager (RevMan) The Cochrane Collaboration 2025"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0074|cit74","unstructured":"Higgins JP Altman DG Sterne JA Chapter 8: Assessing risk of bias in included studies. In: Higgins JP, Churchill R, Chandler J, Cumpston MS, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.2.0 (updated June 2017). Cochrane, 2017 Available from https:\/\/www.cochrane.org\/authors\/handbooks-and-manuals\/handbook\/archive\/v5.2.0"},{"issue":"7382","key":"10.1002\/14651858.CD011506.pub3-BIB0075|cit75","first-page":"219","article-title":"Interaction revisited: the difference between two estimates","volume":"326","author":"Altman","year":"2003","journal-title":"BMJ (Clinical Research Ed.)"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0076|cit76","unstructured":"Thorlund K Engstrom J Wetterslev J Brok J Imberger G Gluud C User Manual for Trial Sequential Analysis (TSA) [Online] Copenhagen Copenhagen Trial Unit ctu.dk\/wp-content\/uploads\/2021\/03\/2017-10-10-TSA-Manual-ENG_ER.pdf"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0077|cit77","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12874-017-0315-7","article-title":"Trial Sequential Analysis in systematic reviews with meta-analysis","volume":"17","author":"Wetterslev","year":"2017","journal-title":"BMC Medical Research Methodology"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0078|cit78","unstructured":"Copenhagen Trial Unit's Trial Sequential Analysis Software Copenhagen Trial Unit 2024"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0079|cit79","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.jclinepi.2007.03.013","article-title":"Trial sequential analysis may establish when firm evidence is reached in cumulative meta-analysis","volume":"61","author":"Wetterslev","year":"2008","journal-title":"Journal of Clinical Epidemiology"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0080|cit80","unstructured":"Sch\u00fcnemann H Bro\u017cek J Guyatt G Oxman A Handbook for grading the quality of evidence and the strength of recommendations using the GRADE approach (updated October 2013). GRADE Working Group, 2013 Available from https:\/\/gdt.gradepro.org\/app\/handbook\/handbook.html"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0081|cit81","unstructured":"GRADEpro GDT McMaster University (developed by Evidence Prime) 2024"},{"issue":"16","key":"10.1002\/14651858.CD011506.pub3-BIB0082|cit82","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.1056\/NEJMoa2207554","article-title":"Cerebral oximetry monitoring in extremely preterm infants","volume":"388","author":"Hansen","year":"2023","journal-title":"New England Journal of Medicine"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0083|cit83","unstructured":"SafeBoosC III two-year follow-up https:\/\/clinicaltrials.gov\/study\/NCT05134116"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0084|cit84","unstructured":"Safeguarding the brain of our smallest infants phase III (SafeBoosC) https:\/\/clinicaltrials.gov\/show\/NCT03770741"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0085|cit85","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1186\/s13063-019-3756-y","article-title":"Detailed statistical analysis plan for the SafeBoosC III trial: a multinational randomised clinical trial assessing treatment guided by cerebral oxygenation monitoring versus treatment as usual in extremely preterm infants","volume":"20","author":"Hansen","year":"2019","journal-title":"Trials"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0086|cit86","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1186\/s13063-023-07653-x","article-title":"Cerebral oximetry monitoring versus usual care for extremely preterm infants: a study protocol for the 2-year follow-up of the SafeBoosC-III randomised clinical trial","volume":"24","author":"Rasmussen","year":"2023","journal-title":"Trials"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0087|cit87","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1186\/s13063-023-07720-3","article-title":"Detailed statistical analysis plan for a secondary Bayesian analysis of the SafeBoosC-III trial: a multinational, randomised clinical trial assessing treatment guided by cerebral oximetry monitoring versus usual care in extremely preterm infants","volume":"24","author":"Olsen","year":"2023","journal-title":"Trials"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0088|cit88","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1186\/s13063-019-3955-6","article-title":"Cerebral near-infrared spectroscopy monitoring versus treatment as usual for extremely preterm infants: a protocol for the SafeBoosC randomised clinical phase III trial","volume":"20","author":"Hansen","year":"2019","journal-title":"Trials"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0089|cit89","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1186\/s13063-024-08074-0","article-title":"Alternative consent methods used in the multinational, pragmatic, randomised clinical trial SafeBoosC-III","volume":"25","author":"Vestager","year":"2024","journal-title":"Trials"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0090|cit90","doi-asserted-by":"publisher","first-page":"e072313. Erratu","DOI":"10.1136\/bmj-2022-072313","article-title":"Cerebral regional tissue Oxygen Saturation to Guide Oxygen Delivery in preterm neonates during immediate transition after birth (COSGOD III): multicentre randomised phase 3 clinical trial","volume":"380","author":"Pichler","year":"2023","journal-title":"BMJ (Clinical Research Ed.)"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0091|cit91","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1186\/s13063-019-3258-y","article-title":"Cerebral regional tissue Oxygen Saturation to Guide Oxygen Delivery in preterm neonates during immediate transition after birth (COSGOD III): an investigator-initiated, randomized, multi-center, multi-national, clinical trial on additional cerebral tissue","volume":"20","author":"Pichler","year":"2019","journal-title":"Trials"},{"issue":"10","key":"10.1002\/14651858.CD011506.pub3-BIB0092|cit92","doi-asserted-by":"publisher","first-page":"4425","DOI":"10.1007\/s00431-024-05711-3","article-title":"Cerebral oxygenation during immediate fetal-to-neonatal transition and fidgety movements between six to 20 weeks of corrected age: an ancillary study to the COSGOD III trial","volume":"183","author":"Wolfsberger","year":"2024","journal-title":"European Journal of Pediatrics"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0093|cit93","unstructured":"2 year follow up of COSGOD III (COSGODIII-FU) https:\/\/clinicaltrials.gov\/study\/NCT06141733"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0094|cit94","unstructured":"Cerebral regional tissue oxygen saturation to guide oxygen delivery in preterm neonates during immediate transition (COSGOD) https:\/\/clinicaltrials.gov\/show\/NCT03166722"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0095|cit95","doi-asserted-by":"publisher","first-page":"g7635","DOI":"10.1136\/bmj.g7635","article-title":"Cerebral near infrared spectroscopy oximetry in extremely preterm infants: Phase II randomised clinical trial","volume":"350","author":"Hyttel-Sorensen","year":"2015","journal-title":"BMJ (Clinical Research Ed.)"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0096|cit96","doi-asserted-by":"publisher","first-page":"e0262640","DOI":"10.1371\/journal.pone.0262640","article-title":"Early cerebral hypoxia in extremely preterm infants and neurodevelopmental impairment at 2 year of age: a post hoc analysis of the SafeBoosC II trial","volume":"17","author":"Plomgaard","year":"2022","journal-title":"PloS One"},{"issue":"2","key":"10.1002\/14651858.CD011506.pub3-BIB0097|cit97","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1111\/apa.14463","article-title":"No neurodevelopmental benefit of cerebral oximetry in the first randomised trial (SafeBoosC II) in preterm infants during the first days of life","volume":"108","author":"Plomgaard","year":"2019","journal-title":"Acta Paediatrica"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0098|cit98","unstructured":"Safeguarding the brain of our smallest children; an investigator-initiated randomised, blinded, multinational, phase II feasibility clinical trial on near-infrared spectroscopy monitoring combined with defined treatment guidelines versus standard monitoring and treatment as usual in preterm infants - SafeBoosC https:\/\/onderzoekmetmensen.nl\/en\/trial\/37782"},{"issue":"3","key":"10.1002\/14651858.CD011506.pub3-BIB0099|cit99","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1038\/pr.2015.239","article-title":"Brain injury in the international multicenter randomized SafeBoosC phase II feasibility trial: cranial ultrasound and magnetic resonance imaging assessments","volume":"79","author":"Plomgaard","year":"2016","journal-title":"Pediatric Research"},{"issue":"3","key":"10.1002\/14651858.CD011506.pub3-BIB0100|cit100","doi-asserted-by":"publisher","first-page":"e0173440","DOI":"10.1371\/journal.pone.0173440","article-title":"Early biomarkers of brain injury and cerebral hypo- and hyperoxia in the SafeBoosC II trial","volume":"12","author":"Plomgaard","year":"2017","journal-title":"PloS One"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0101|cit101","unstructured":"SafeBoosC - a phase II trial (SafeBoosC) https:\/\/clinicaltrials.gov\/study\/NCT01590316"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0102|cit102","unstructured":"The effect of targeting brain oxygenation on neuro-developmental outcomes in extremely pre-term infants: a pilot blinded randomised controlled trial https:\/\/trialsearch.who.int\/Trial2.aspx?TrialID=ACTRN12621000778886"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0103|cit103","unstructured":"Application of near infrared spectroscopy in mechanical ventilation of premature infants https:\/\/trialsearch.who.int\/Trial2.aspx?TrialID=ChiCTR2100051928"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0104|cit104","unstructured":"Neonatal brain oxygenation study (BOX) https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04439968"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0105|cit105","unstructured":"Safeboosc-iiiv - does cerebral oximetry monitoring affect renal outcomes (sbiiivr) https:\/\/clinicaltrials.gov\/study\/NCT06926946"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0106|cit106","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1186\/s13063-023-07699-x","article-title":"The effects of cerebral oximetry in mechanically ventilated newborns: a protocol for the SafeBoosC-IIIv randomised clinical trial","volume":"24","author":"Vestager","year":"2023","journal-title":"Trials"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0107|cit107","unstructured":"Safeguarding the brain of our smallest children-iiiv (safeboosc-iiiv) https:\/\/clinicaltrials.gov\/ct2\/show\/NCT05907317"},{"issue":"1","key":"10.1002\/14651858.CD011506.pub3-BIB0108|cit108","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1186\/s13643-018-0770-1","article-title":"Assessing imprecision in Cochrane systematic reviews: a comparison of GRADE and Trial Sequential Analysis","volume":"7","author":"Castellini","year":"2018","journal-title":"Systematic Reviews"},{"key":"10.1002\/14651858.CD011506.pub3-BIB0109|cit109","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.jclinepi.2018.10.009","article-title":"Increased risks for random errors are common in outcomes graded as high certainty of evidence","volume":"106","author":"Gartlehner","year":"2019","journal-title":"Clinical Epidemiology"},{"issue":"19","key":"10.1002\/14651858.CD011506.pub3-BIB0110|cit110","doi-asserted-by":"publisher","first-page":"1737","DOI":"10.1001\/archinternmed.2009.313","article-title":"Adverse events in randomized trials: neglected, restricted, distorted, and silenced","volume":"169","author":"Ioannidis","year":"2009","journal-title":"Archives of Internal Medicine"},{"issue":"4","key":"10.1002\/14651858.CD011506.pub3-BIB0111|cit111","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1038\/s41390-022-01995-z","article-title":"Cerebral near-infrared spectroscopy monitoring (NIRS) in children and adults: a systematic review with meta-analysis","volume":"96","author":"Hansen","journal-title":"2024"},{"issue":"2","key":"10.1002\/14651858.CD011506.pub3-BIB0112|cit112","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1038\/s41390-018-0026-8","article-title":"Monitoring cerebral oxygenation of the immature brain: a neuroprotective strategy?","volume":"84","author":"Bel","year":"2018","journal-title":"Pediatric Research"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:05:35Z","timestamp":1791763535000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD011506.pub3"}},"subtitle":[],"editor":[{"name":"Cochrane Central Editorial Service","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,1,7]]},"references-count":112,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd011506.pub3","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,7]]}}}