{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:23:43Z","timestamp":1791822223835,"version":"4.3.4"},"reference-count":67,"publisher":"Wiley","issue":"12","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd011952","type":"journal-article","created":{"date-parts":[[2015,12,12]],"date-time":"2015-12-12T13:12:04Z","timestamp":1449925924000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Ascorbic acid for the treatment of Charcot-Marie-Tooth disease"],"prefix":"10.1002","volume":"2015","author":[{"given":"Burkhard","family":"Gess","sequence":"first","affiliation":[{"name":"University Hospital RWTH Aachen; Department of Neurology; Pauwelsstra\u00dfe 30 Aachen Germany 52074"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Baets","sequence":"additional","affiliation":[{"name":"VIB; Neurogenetics Group, Department of Molecular Genetics; Antwerp Belgium 2610"},{"name":"University of Antwerp; Laboratory of Neurogenetics, Institute Born-Bunge; Antwerp Belgium"},{"name":"Antwerp University Hospital (UZA); Department of Neurology; Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"De Jonghe","sequence":"additional","affiliation":[{"name":"VIB; Neurogenetics Group, Department of Molecular Genetics; Antwerp Belgium 2610"},{"name":"University of Antwerp; Laboratory of Neurogenetics, Institute Born-Bunge; Antwerp Belgium"},{"name":"Antwerp University Hospital (UZA); Department of Neurology; Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary M","family":"Reilly","sequence":"additional","affiliation":[{"name":"National Hospital for Neurology and Neurosurgery and UCL Institute of Neurology; MRC Centre for Neuromuscular Diseases; Queen Square London UK WC1N 3BG"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Pareyson","sequence":"additional","affiliation":[{"name":"IRCCS Foundation, C. Besta Neurological Institute; Unit of Clinics of Central and Peripheral Degenerative Neuropathies, Department of Clinical Neuroscience; Via Celoria 11 Milan Italy 20133"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Young","sequence":"additional","affiliation":[{"name":"University Hospital of M\u00fcnster; Department of Sleep Medicine and Neuromuscular Disorders; Albert-Schweitzer-Campus 1, Geb\u00e4ude A M\u00fcnster Germany 48129"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,11]]},"reference":[{"issue":"6","key":"10.1002\/14651858.CD011952-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S1474-4422(09)70108-5","article-title":"Ascorbic acid for Charcot-Marie-Tooth disease type 1A in children: a randomised, double-blind, placebo-controlled, safety and efficacy trial","volume":"8","author":"Burns","year":"2009","journal-title":"Lancet Neurology"},{"issue":"8","key":"10.1002\/14651858.CD011952-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1001\/jamaneurol.2013.3178","article-title":"High-dosage ascorbic acid treatment in Charcot-Marie-Tooth disease type 1A: results of a randomized, double-masked, controlled trial","volume":"70","author":"Lewis","year":"2013","journal-title":"JAMA Neurology"},{"key":"10.1002\/14651858.CD011952-BIB0003|cit3","unstructured":"Mazanec R CMT Cochrane Review [personal communication] Email to: B Gess"},{"issue":"12","key":"10.1002\/14651858.CD011952-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/S1474-4422(09)70260-1","article-title":"Effect of ascorbic acid in patients with Charcot-Marie-Tooth disease type 1A: a multicentre, randomised, double-blind, placebo-controlled trial","volume":"8","author":"Micallef","year":"2009","journal-title":"Lancet Neurology"},{"issue":"4","key":"10.1002\/14651858.CD011952-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/S1474-4422(11)70025-4","article-title":"Ascorbic acid in Charcot-Marie-Tooth disease type 1A (CMT-TRIAAL and CMT-TRAUK): a double-blind randomised trial","volume":"10","author":"Pareyson","year":"2001","journal-title":"Lancet Neurology"},{"key":"10.1002\/14651858.CD011952-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/1741-7015-7-70","article-title":"Oral high dose ascorbic acid treatment for one year in young CMT1A patients: a randomised, double-blind, placebo-controlled phase II trial","volume":"7","author":"Verhamme","year":"2009","journal-title":"BMC Medicine"},{"issue":"2","key":"10.1002\/14651858.CD011952-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/j.1600-0404.2008.01134.x","article-title":"Poor tolerability of high dose ascorbic acid in a population of genetically confirmed adult Charcot-Marie-Tooth 1A patients","volume":"120","author":"Toth","year":"2009","journal-title":"Acta Neurologica Scandinavica"},{"issue":"4","key":"10.1002\/14651858.CD011952-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"336","DOI":"10.2165\/00019053-199610040-00004","article-title":"A review of the progress towards developing health-related quality-of-life instruments for international clinical studies and outcomes research","volume":"10","author":"Anderson","year":"1996","journal-title":"Pharmacoeconomics"},{"key":"10.1002\/14651858.CD011952-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/B978-0-444-52902-2.00050-3","article-title":"Hereditary sensory and autonomic neuropathies","volume":"115","author":"Auer-Grumbach","year":"2013","journal-title":"Handbook of Clinical Neurology"},{"issue":"5","key":"10.1002\/14651858.CD011952-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1097\/WCO.0000000000000131","article-title":"Recent advances in Charcot-Marie-Tooth disease","volume":"27","author":"Baets","year":"2014","journal-title":"Current Opinion in Neurology"},{"issue":"1","key":"10.1002\/14651858.CD011952-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/ng796","article-title":"Ganglioside-induced differentiation-associated protein-1 is mutant in Charcot-Marie-Tooth disease type 4A\/8q21","volume":"30","author":"Baxter","year":"2002","journal-title":"Nature Genetics"},{"key":"10.1002\/14651858.CD011952-BIB0012|cit12","unstructured":"Bird TD Charcot-Marie-Tooth Hereditary Neuropathy Overview Pagon RA Adam MP Ardinger HH Wallace SE Amemiya A Bean LJH GeneReviews [Internet] Seattle University of Washington"},{"issue":"iv","key":"10.1002\/14651858.CD011952-BIB0013|cit13","first-page":"22","article-title":"Genetic epidemiology of Charcot-Marie-Tooth disease","volume":"193","author":"Braathen","year":"2012","journal-title":"Acta Neurologica Scandinavica Supplement"},{"issue":"5","key":"10.1002\/14651858.CD011952-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1002\/ana.23572","article-title":"Validation of the Charcot-Marie-Tooth disease pediatric scale as an outcome measure of disability","volume":"71","author":"Burns","year":"2012","journal-title":"Annals of Neurology"},{"issue":"1","key":"10.1002\/14651858.CD011952-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0092-8674(93)90058-X","article-title":"DNA deletion associated with hereditary neuropathy with liability to pressure palsies","volume":"72","author":"Chance","year":"1993","journal-title":"Cell"},{"issue":"8","key":"10.1002\/14651858.CD011952-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1212\/WNL.53.8.1660","article-title":"Total neuropathy score: validation and reliability study","volume":"53","author":"Cornblath","year":"1999","journal-title":"Neurology"},{"issue":"8","key":"10.1002\/14651858.CD011952-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.biocel.2012.04.020","article-title":"Charcot-Marie-Tooth disease: emerging mechanisms and therapies","volume":"44","author":"d'Ydewalle","year":"2012","journal-title":"International Journal of Biochemistry and Cell Biology"},{"key":"10.1002\/14651858.CD011952-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/B978-0-7216-9491-7.50043-0","article-title":"Quantitating overall neuropathic symptoms, impairments, and outcomes","volume-title":"Peripheral Neuropathy","author":"Dyck","year":"2005"},{"issue":"2","key":"10.1002\/14651858.CD011952-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1083\/jcb.105.2.1023","article-title":"Differentiation of axon-related Schwann cells in vitro. I. Ascorbic acid regulates basal lamina assembly and myelin formation","volume":"105","author":"Eldridge","year":"1987","journal-title":"Journal of Cell Biology"},{"issue":"2","key":"10.1002\/14651858.CD011952-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.1750-3639.1993.tb00738.x","article-title":"Hereditary demyelinating motor and sensory neuropathy","volume":"3","author":"Gabreels-Festen","year":"1993","journal-title":"Brain Pathology"},{"issue":"3","key":"10.1002\/14651858.CD011952-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/glia.20923","article-title":"Sodium-dependent vitamin C transporter 2 (SVCT2) is necessary for the uptake of L-ascorbic acid into Schwann cells","volume":"58","author":"Gess","year":"2010","journal-title":"Glia"},{"issue":"47","key":"10.1002\/14651858.CD011952-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"17180","DOI":"10.1523\/JNEUROSCI.3457-11.2011","article-title":"Sodium-dependent vitamin C transporter 2 deficiency causes hypomyelination and extracellular matrix defects in the peripheral nervous system","volume":"31","author":"Gess","year":"2011","journal-title":"Journal of Neuroscience"},{"issue":"8","key":"10.1002\/14651858.CD011952-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.nmd.2013.05.005","article-title":"Charcot-Marie-Tooth disease: frequency of genetic subtypes in a German neuromuscular center population","volume":"23","author":"Gess","year":"2013","journal-title":"Neuromuscular Disorders"},{"key":"10.1002\/14651858.CD011952-BIB0024|cit24","unstructured":"McMaster University GRADEpro GDT: GRADEpro Guideline Development Tool [Software].(developed by Evidence Prime, Inc.). Available from gradepro.org Computer program on www.gradepro.org] 2015"},{"issue":"1","key":"10.1002\/14651858.CD011952-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s11940-005-0003-5","article-title":"Current therapy for Charcot-Marie-Tooth disease","volume":"7","author":"Grandis","year":"2005","journal-title":"Current Treatment Options in Neurology"},{"issue":"2","key":"10.1002\/14651858.CD011952-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s004010000275","article-title":"Pathological findings in the x-linked form of Charcot-Marie-Tooth disease: a morphometric and ultrastructural analysis","volume":"101","author":"Hahn","year":"2001","journal-title":"Acta Neuropathologica (Berlin)"},{"issue":"2","key":"10.1002\/14651858.CD011952-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1093\/brain\/103.2.259","article-title":"The clinical features of hereditary motor and sensory neuropathy types I and II","volume":"103","author":"Harding","year":"1980","journal-title":"Brain"},{"issue":"2","key":"10.1002\/14651858.CD011952-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1006\/geno.1993.1462","article-title":"Structure and localization of the gene encoding human peripheral myelin protein 2 (PMP2)","volume":"18","author":"Hayasaka","year":"1993","journal-title":"Genomics"},{"issue":"3","key":"10.1002\/14651858.CD011952-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/ng1193-266","article-title":"De novo mutation of the myelin P0 gene in Dejerine-Sottas disease (hereditary motor and sensory neuropathy type III)","volume":"5","author":"Hayasaka","year":"1993","journal-title":"Nature Genetics"},{"issue":"3","key":"10.1002\/14651858.CD011952-BIB0030|cit30","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1006\/bbrc.1993.1968","article-title":"Mutation of the myelin P0 gene in Charcot-Marie-tooth neuropathy type 1","volume":"194","author":"Hayasaka","year":"1993","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"10.1002\/14651858.CD011952-BIB0031|cit31","unstructured":"Higgins JPT Green S (editors) Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011] The Cochrane Collaboration. Available from www.cochrane-handbook.org 2011"},{"issue":"6890","key":"10.1002\/14651858.CD011952-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1136\/bmj.306.6890.1437","article-title":"Short form 36 (SF36) health survey questionnaire: normative data for adults of working age","volume":"306","author":"Jenkinson","year":"1993","journal-title":"BMJ"},{"issue":"4","key":"10.1002\/14651858.CD011952-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1002\/mus.23614","article-title":"Anterior tibialis CMAP amplitude correlations with impairment in CMT1A","volume":"47","author":"Komyathy","year":"2013","journal-title":"Muscle & Nerve"},{"key":"10.1002\/14651858.CD011952-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1111\/j.1749-6632.1999.tb08618.x","article-title":"Correlation between weakness and axonal loss in patients with CMT1A","volume":"883","author":"Krajewski","year":"1999","journal-title":"Annals of the New York Academy of Science"},{"issue":"Pt 7","key":"10.1002\/14651858.CD011952-BIB0035|cit35","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1093\/brain\/123.7.1516","article-title":"Neurological dysfunction and axonal degeneration in Charcot-Marie-Tooth disease type 1A","volume":"123","author":"Krajewski","year":"2000","journal-title":"Brain"},{"issue":"5","key":"10.1002\/14651858.CD011952-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1159\/000065643","article-title":"An epidemiological genetic study of Charcot-Marie-Tooth disease in Western Japan","volume":"21","author":"Kurihara","year":"2002","journal-title":"Neuroepidemiology"},{"key":"10.1002\/14651858.CD011952-BIB0037|cit37","doi-asserted-by":"crossref","unstructured":"Liu L Zhang R Intermediate Charcot-Marie-Tooth disease Neuroscience Bulletin 2014 999 1009","DOI":"10.1007\/s12264-014-1475-7"},{"issue":"2","key":"10.1002\/14651858.CD011952-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0092-8674(91)90613-4","article-title":"DNA duplication associated with Charcot-Marie-Tooth disease type 1A","volume":"66","author":"Lupski","year":"1991","journal-title":"Cell"},{"issue":"11","key":"10.1002\/14651858.CD011952-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/j.nmd.2014.06.431","article-title":"Selected items from the Charcot-Marie-Tooth (CMT) Neuropathy Score and secondary clinical outcome measures serve as sensitive clinical markers of disease severity in CMT1A patients","volume":"24","author":"Mannil","year":"2014","journal-title":"Neuromuscular Disorders"},{"issue":"4","key":"10.1002\/14651858.CD011952-BIB0040|cit40","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1002\/mus.1027","article-title":"The effect of myelinating Schwann cells on axons","volume":"24","author":"Martini","year":"2001","journal-title":"Muscle & Nerve"},{"issue":"4","key":"10.1002\/14651858.CD011952-BIB0041|cit41","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1212\/WNL.54.4.943","article-title":"Psychometric evaluation of a new sensory scale in immune-mediated polyneuropathies. Inflammatory Neuropathy Cause and Treatment (INCAT) Group","volume":"54","author":"Merkies","year":"2000","journal-title":"Neurology"},{"issue":"3","key":"10.1002\/14651858.CD011952-BIB0042|cit42","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1529-8027.2011.00350.x","article-title":"Reliability of the CMT neuropathy score (second version) in Charcot-Marie-Tooth disease","volume":"16","author":"Murphy","year":"2011","journal-title":"Journal of the Peripheral Nervous System"},{"issue":"7","key":"10.1002\/14651858.CD011952-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1136\/jnnp-2012-302451","article-title":"Charcot-Marie-Tooth disease: frequency of genetic subtypes and guidelines for genetic testing","volume":"83","author":"Murphy","year":"2012","journal-title":"Journal of Neurology, Neurosurgery & Psychiatry"},{"issue":"1","key":"10.1002\/14651858.CD011952-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000472166","article-title":"Estimation of the mutation frequencies in Charcot-Marie-Tooth disease type 1 and hereditary neuropathy with liability to pressure palsies: a European collaborative study","volume":"4","author":"Nelis","year":"1996","journal-title":"European Journal of Human Genetics"},{"issue":"12","key":"10.1002\/14651858.CD011952-BIB0045|cit45","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.1212\/WNL.43.12.2558","article-title":"Intermediate nerve conduction velocities define X-linked Charcot-Marie-Tooth neuropathy families","volume":"43","author":"Nicholson","year":"1993","journal-title":"Neurology"},{"issue":"6","key":"10.1002\/14651858.CD011952-BIB0046|cit46","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1093\/brain\/awu071","article-title":"PMP22 messenger RNA levels in skin biopsies: testing the effectiveness of a Charcot-Marie-Tooth 1A biomarker","volume":"127","author":"Nobbio","year":"2014","journal-title":"Brain"},{"key":"10.1002\/14651858.CD011952-BIB0047|cit47","doi-asserted-by":"crossref","unstructured":"Pareyson D Saveri P Piscosquito G Charcot-Marie-Tooth disease and related hereditary neuropathies: from gene function to associated phenotypes Current Molecular Medicine 2014","DOI":"10.2174\/1566524014666141010154205"},{"issue":"4","key":"10.1002\/14651858.CD011952-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/nm1023","article-title":"Ascorbic acid treatment corrects the phenotype of a mouse model of Charcot-Marie-Tooth disease","volume":"10","author":"Passage","year":"2004","journal-title":"Nature Medicine"},{"issue":"2","key":"10.1002\/14651858.CD011952-BIB0049|cit49","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0960-8966(91)90055-W","article-title":"Duplication in chromosome 17p11.2 in Charcot-Marie-Tooth neuropathy type 1a (CMT 1a). The HMSN Collaborative Research Group","volume":"1","author":"Raeymaekers","year":"1991","journal-title":"Neuromuscular Disorders"},{"issue":"6","key":"10.1002\/14651858.CD011952-BIB0050|cit50","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.nmd.2006.03.008","article-title":"136th ENMC International Workshop: Charcot-Marie-Tooth disease type 1A (CMT1A)8-10 April 2005, Naarden, The Netherlands","volume":"16","author":"Reilly","year":"2006","journal-title":"Neuromuscular Disorders"},{"key":"10.1002\/14651858.CD011952-BIB0051|cit51","unstructured":"The Nordic Cochrane Center, The Cochrane Collaboration Review Manager (RevMan) 2014"},{"issue":"1","key":"10.1002\/14651858.CD011952-BIB0052|cit52","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1136\/jnnp-2011-300952","article-title":"The distal hereditary motor neuropathies","volume":"83","author":"Rossor","year":"2012","journal-title":"Journal of Neurology, Neurosurgery & Psychiatry"},{"issue":"10","key":"10.1002\/14651858.CD011952-BIB0053|cit53","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1038\/nrneurol.2013.179","article-title":"Clinical implications of genetic advances in Charcot-Marie-Tooth disease","volume":"9","author":"Rossor","year":"2013","journal-title":"Nature Reviews Neurology"},{"issue":"1","key":"10.1002\/14651858.CD011952-BIB0054|cit54","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/ana.22166","article-title":"Charcot-Marie-Tooth disease subtypes and genetic testing strategies","volume":"69","author":"Saporta","year":"2011","journal-title":"Annals of Neurology"},{"issue":"5","key":"10.1002\/14651858.CD011952-BIB0055|cit55","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1086\/379525","article-title":"Mutations in a gene encoding a novel SH3\/TPR domain protein cause autosomal recessive Charcot-Marie-Tooth type 4C neuropathy","volume":"73","author":"Senderek","year":"2003","journal-title":"American Journal of Human Genetics"},{"issue":"7","key":"10.1002\/14651858.CD011952-BIB0056|cit56","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1212\/01.WNL.0000156517.00615.A3","article-title":"Reliability and validity of the CMT neuropathy score as a measure of disability","volume":"64","author":"Shy","year":"2005","journal-title":"Neurology"},{"key":"10.1002\/14651858.CD011952-BIB0057|cit57","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1016\/B978-0-7216-9491-7.50072-7","article-title":"Hereditary motor and sensory neuropathy","volume-title":"Peripheral Neuropathy","volume":"2","author":"Shy","year":"2005"},{"issue":"3","key":"10.1002\/14651858.CD011952-BIB0058|cit58","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/ng0692-171","article-title":"The peripheral myelin protein gene PMP-22 is contained within the Charcot-Marie-Tooth disease type 1A duplication","volume":"1","author":"Timmerman","year":"1992","journal-title":"Nature Genetics"},{"issue":"5","key":"10.1002\/14651858.CD011952-BIB0059|cit59","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/WCO.0b013e328364c04b","article-title":"The various Charcot-Marie-Tooth diseases","volume":"26","author":"Vallat","year":"2013","journal-title":"Current Opinion in Neurology"},{"issue":"5","key":"10.1002\/14651858.CD011952-BIB0060|cit60","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1161\/01.STR.19.5.604","article-title":"Interobserver agreement for the assessment of handicap in stroke patients","volume":"19","author":"Swieten","year":"1988","journal-title":"Stroke"},{"issue":"Pt 12","key":"10.1002\/14651858.CD011952-BIB0061|cit61","doi-asserted-by":"crossref","first-page":"3252","DOI":"10.1093\/brain\/awp251","article-title":"The natural history of Charcot-Marie-Tooth type 1A in adults: a 5-year follow-up study","volume":"132","author":"Verhamme","year":"2009","journal-title":"Brain"},{"issue":"Pt 8","key":"10.1002\/14651858.CD011952-BIB0062|cit62","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1093\/brain\/awl126","article-title":"MFN2 mutation distribution and genotype\/phenotype correlation in Charcot-Marie-Tooth type 2","volume":"129","author":"Verhoeven","year":"2006","journal-title":"Brain"},{"issue":"2-3","key":"10.1002\/14651858.CD011952-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0165-0173(01)00097-2","article-title":"Disease mechanisms and potential therapeutic strategies in Charcot-Marie-Tooth disease","volume":"36","author":"Young","year":"2001","journal-title":"Brain Research. Brain Research Reviews"},{"issue":"10","key":"10.1002\/14651858.CD011952-BIB0064|cit64","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1038\/ng.2406","article-title":"Loss-of-function mutations in HINT1 cause axonal neuropathy with neuromyotonia","volume":"44","author":"Zimo\u0144","year":"2012","journal-title":"Nature Genetics"},{"issue":"5","key":"10.1002\/14651858.CD011952-BIB0065|cit65","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/ng1341","article-title":"Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A","volume":"36","author":"Zuchner","year":"2004","journal-title":"Nature Genetics"},{"issue":"2","key":"10.1002\/14651858.CD011952-BIB0066|cit66","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006052","article-title":"Treatment for Charcot-Marie-Tooth disease","author":"Young","year":"2006","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD011952-BIB0067|cit67","doi-asserted-by":"crossref","unstructured":"Young P De Jonghe P St\u00f6gbauer F Butterfass-Bahloul T Treatment for Charcot-Marie-Tooth disease Cochrane Database of Systematic Reviews 2008","DOI":"10.1002\/14651858.CD006052.pub2"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/14651858.CD011952\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T00:44:22Z","timestamp":1718239462000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD011952"}},"subtitle":[],"editor":[{"name":"Cochrane Neuromuscular Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,12,11]]},"references-count":67,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2015,12]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd011952","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,11]]}}}