{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T12:04:27Z","timestamp":1792843467204,"version":"4.5.0"},"update-to":[{"DOI":"10.1002\/14651858.cd012234","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2017,10,30]],"date-time":"2017-10-30T00:00:00Z","timestamp":1509321600000}}],"reference-count":199,"publisher":"Wiley","issue":"10","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd012234.pub2","type":"journal-article","created":{"date-parts":[[2017,10,30]],"date-time":"2017-10-30T12:56:28Z","timestamp":1509368188000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Intracavity lavage and wound irrigation for prevention of surgical site infection"],"prefix":"10.1002","volume":"2017","author":[{"given":"Gill","family":"Norman","sequence":"first","affiliation":[{"name":"University of Manchester, Manchester Academic Health Science Centre; Division of Nursing, Midwifery & Social Work, School of Health Sciences, Faculty of Biology, Medicine & Health; Jean McFarlane Building Oxford Road Manchester UK M13 9PL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ross A","family":"Atkinson","sequence":"additional","affiliation":[{"name":"University of Manchester, Manchester Academic Health Science Centre; Division of Nursing, Midwifery & Social Work, School of Health Sciences, Faculty of Biology, Medicine & Health; Jean McFarlane Building Oxford Road Manchester UK M13 9PL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanya A","family":"Smith","sequence":"additional","affiliation":[{"name":"Southmead Hospital, North Bristol Foundation Trust; Trauma and Orthopaedics; Southmead Way Bristol Avon UK BS10 5NB"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ceri","family":"Rowlands","sequence":"additional","affiliation":[{"name":"Severn Deanery, Health Education South West, England; General Surgery; Flat 407, 51.02 Apartments Bristol UK BS1 3LY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amber D","family":"Rithalia","sequence":"additional","affiliation":[{"name":"Independent Researcher; 7 Victoria Terrace, Kirkstall Leeds UK LS5 3HX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma J","family":"Crosbie","sequence":"additional","affiliation":[{"name":"Faculty of Biology, Medicine and Health, University of Manchester; Division of Cancer Sciences; 5th Floor - Research St Mary's Hospital Manchester UK M13 9WL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo C","family":"Dumville","sequence":"additional","affiliation":[{"name":"University of Manchester, Manchester Academic Health Science Centre; Division of Nursing, Midwifery & Social Work, School of Health Sciences, Faculty of Biology, Medicine & Health; Jean McFarlane Building Oxford Road Manchester UK M13 9PL"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,10,30]]},"reference":[{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"233","DOI":"10.5144\/0256-4947.1994.233","article-title":"Topical ampicillin for prophylaxis against wound infection in acute appendicitis","volume":"14","author":"Al-Shehri","year":"1994","journal-title":"Annals of Saudi Medicine"},{"issue":"7","key":"10.1002\/14651858.CD012234.pub2-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1002\/bjs.1800810743","article-title":"Taurolidine peritoneal lavage as prophylaxis against infection after elective colorectal surgery","volume":"81","author":"Baker","year":"1994","journal-title":"British Journal of Surgery"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0003|cit3","first-page":"144","article-title":"Taurolidine peritoneal lavage as a prophylaxis against post-operative infection in colorectal surgery: a randomised double-blind controlled trial of 300 patients","volume":"163","author":"Baker","year":"1994","journal-title":"Irish Journal of Medical Science"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0002-9378(85)90113-9","article-title":"Antibiotic irrigation prophylaxis in the high-risk cesarean section patient","volume":"155","author":"Bourgeois","year":"1985","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"5","key":"10.1002\/14651858.CD012234.pub2-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1016\/j.fertnstert.2006.12.084","article-title":"Adept (icodextrin 4% solution) reduces adhesions after laparoscopic surgery for adhesiolysis: a double-blind, randomized, controlled study","volume":"88","author":"Brown","year":"2007","journal-title":"Fertility and Sterility"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0006|cit6","first-page":"721","article-title":"A controlled trial of taurolin in established bacterial peritonitis","volume":"146","author":"Browne","year":"1978","journal-title":"Surgery, Gynecology and Obstetrics"},{"issue":"4","key":"10.1002\/14651858.CD012234.pub2-BIB0007|cit7","first-page":"277","article-title":"Perforated appendicitis with generalized peritonitis. Prospective, randomized evaluation of closed postoperative peritoneal lavage","volume":"157","author":"Buanes","year":"1991","journal-title":"European Journal of Surgery"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0008|cit8","first-page":"S96","article-title":"Normal saline, pelvic and intrauterine irrigation in the high risk cesarean section (CS) patient as a safe and cost-effective method of infection prophylaxis","volume":"182","author":"Carl","year":"2000","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0009|cit9","first-page":"103","article-title":"Does lavage of mastectomy wounds with strong tetracycline solution reduce the incidence of postoperative seroma?","volume":"2","author":"Case","year":"1987","journal-title":"Surgical Research Communications"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0011|cit10","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/s002689910008","article-title":"Syringe pressure irrigation of subdermic tissue after appendectomy to decrease the incidence of postoperative wound infection","volume":"24","author":"Cervantes-Sanchez","year":"2000","journal-title":"World Journal of Surgery"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0010|cit11","first-page":"54","article-title":"Pressure irrigation of the surgical wound in complicated appendicitis","volume":"59","author":"Cervantes-S\u00e1nchez","year":"1996","journal-title":"Revista M\u00e9dica del Hospital General de M\u00e9xico"},{"issue":"6","key":"10.1002\/14651858.CD012234.pub2-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1007\/s00586-005-0975-6","article-title":"Can povidone-iodine solution be used safely in a spinal surgery?","volume":"15","author":"Chang","year":"2006","journal-title":"European Spine Journal"},{"issue":"15","key":"10.1002\/14651858.CD012234.pub2-BIB0013|cit13","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1097\/01.brs.0000171907.60775.85","article-title":"Efficacy of dilute Betadine solution irrigation in the prevention of postoperative infection of spinal surgery","volume":"30","author":"Cheng","year":"2005","journal-title":"Spine"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0014|cit14","first-page":"467","article-title":"Effect of the exchange of saline used in surgical procedures on surgical site infection","volume":"34","author":"Cho","year":"2004","journal-title":"Taehan Kanho Hakhoe Chi"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0015|cit15","first-page":"473","article-title":"Randomized comparison of five irrigation solutions at cesarean section","volume":"68","author":"Dashow","year":"1986","journal-title":"Obstetrics and Gynecology"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0016|cit16","first-page":"221","article-title":"Povidone-iodine irrigation of the subcutaneous tissue to prevent surgical wound infections","volume":"155","author":"Jong","year":"1982","journal-title":"Surgery, Gynecology and Obstetrics"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0017|cit17","first-page":"29","article-title":"Comparison of lavage or intravenous antibiotics at cesarean section","volume":"67","author":"Elliott","year":"1986","journal-title":"Obstetrics and Gynecology"},{"issue":"2 Suppl","key":"10.1002\/14651858.CD012234.pub2-BIB0018|cit18","first-page":"595","article-title":"Wound sepsis after colorectal surgery: the effect of cefotetan lavage","volume":"6","author":"Greig","year":"1987","journal-title":"Chemioterapia"},{"issue":"7","key":"10.1002\/14651858.CD012234.pub2-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"662","DOI":"10.3109\/01443615.2010.494206","article-title":"Does saline irrigation reduce the wound infection in caesarean delivery?","volume":"30","author":"Gungorduk","year":"2010","journal-title":"Journal of Obstetrics and Gynaecology"},{"issue":"10","key":"10.1002\/14651858.CD012234.pub2-BIB0020|cit20","first-page":"673","article-title":"Reduction of wound sepsis after appendicitis: a report of a double-blind trial of taurolin wound irrigation after appendicectomy","volume":"2","author":"Halsall","year":"1981","journal-title":"Pharmatherapeutica"},{"issue":"4","key":"10.1002\/14651858.CD012234.pub2-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.jhin.2005.07.012","article-title":"Does pulse lavage reduce hip hemiarthroplasty infection rates?","volume":"62","author":"Hargrove","year":"2006","journal-title":"Journal of Hospital Infection"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0022|cit22","first-page":"80","article-title":"The effect of intra-abdominal irrigation at cesarean delivery on maternal morbidity: a randomized trial","volume":"101","author":"Harrigill","year":"2003","journal-title":"Obstetrics and Gynecology"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"106","DOI":"10.55095\/achot2008\/018","article-title":"Efficacy of antiseptics in the prevention of post-operative infections of the proximal femur, hip and pelvis regions in orthopedic pediatric patients. Analysis of the first results","volume":"75","author":"Kokavec","year":"2008","journal-title":"Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0024|cit24","first-page":"282","article-title":"Effectiveness of acidic oxidative potential water in peritoneal lavage for perforated appendicitis","volume":"22","author":"Kubota","year":"1999","journal-title":"Asian Journal of Surgery"},{"issue":"7","key":"10.1002\/14651858.CD012234.pub2-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1007\/s00595-014-1050-x","article-title":"Efficacy and safety of strong acid electrolyzed water for peritoneal lavage to prevent surgical site infection in patients with perforated appendicitis","volume":"45","author":"Kubota","year":"2015","journal-title":"Surgery Today"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0002-9378(83)91110-9","article-title":"Reduction of post-cesarean section infectious morbidity by means of antibiotic irrigation","volume":"147","author":"Levin","year":"1983","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0027|cit27","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0002-9610(83)90064-8","article-title":"Prophylactic antibiotic wound irrigation in gastric, biliary, and colonic surgery","volume":"145","author":"Lord","year":"1983","journal-title":"American Journal of Surgery"},{"issue":"6","key":"10.1002\/14651858.CD012234.pub2-BIB0028|cit28","first-page":"922","article-title":"Preoperative skin preparation and intraoperative pelvic irrigation: impact on post-cesarean endometritis and wound infection","volume":"81","author":"Magann","year":"1993","journal-title":"Obstetrics and Gynecology"},{"issue":"Suppl 2","key":"10.1002\/14651858.CD012234.pub2-BIB0029|cit29","first-page":"146","article-title":"Povidone-iodine wound irrigation prior to skin closure at caesarean section to prevent surgical site infection: a randomised controlled trial","volume":"123","author":"Mahomed","year":"2016","journal-title":"BJOG"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0030|cit30","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/ajo.12437","article-title":"The Betadine trial - antiseptic wound irrigation prior to skin closure at caesarean section to prevent surgical site infection: a randomised controlled trial","volume":"56","author":"Mahomed","year":"2016","journal-title":"Australian & New Zealand Journal of Obstetrics & Gynaecology"},{"issue":"6","key":"10.1002\/14651858.CD012234.pub2-BIB0031|cit31","first-page":"739","article-title":"Prevention of parietal septic complications by irrigation of the appendectomy wound","volume":"45","author":"Marti","year":"1979","journal-title":"Helvetica Chirurgica Acta"},{"issue":"11","key":"10.1002\/14651858.CD012234.pub2-BIB0032|cit32","first-page":"71","article-title":"The effect of antibiotic irrigation of surgical incisions in prevention of surgical site infection","volume":"65","author":"Mirsharifi","year":"2008","journal-title":"Tehran University Medical Journal"},{"issue":"4","key":"10.1002\/14651858.CD012234.pub2-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"E228","DOI":"10.1532\/HSF98.20091162","article-title":"Dermacyn irrigation in reducing infection of a median sternotomy wound","volume":"13","author":"Mohd","year":"2010","journal-title":"Heart Surgery Forum"},{"issue":"d","key":"10.1002\/14651858.CD012234.pub2-BIB0034|cit34","first-page":"66","article-title":"Antibiotic wound irrigation in the prevention of surgical wound infection","volume":"19","author":"Moylan","year":"1968","journal-title":"Surgical Forum"},{"issue":"4 (Suppl 1)","key":"10.1002\/14651858.CD012234.pub2-BIB0035|cit35","doi-asserted-by":"crossref","first-page":"S1244","DOI":"10.1016\/S0016-5085(16)34202-0","article-title":"Effect of polyhexanide on the incidence of surgical site infections after colorectal surgery","volume":"150","author":"Neef","year":"2016","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s00268-013-2309-x","article-title":"Pressurized pulse irrigation with saline reduces surgical-site infections following major hepatobiliary and pancreatic surgery: randomized controlled trial","volume":"38","author":"Nikfarjam","year":"2014","journal-title":"World Journal of Surgery"},{"issue":"1-2","key":"10.1002\/14651858.CD012234.pub2-BIB0037|cit37","first-page":"133","article-title":"Prevention of infection at the operative site: irrigation with iodine derivatives, or NaCl. A prospective and randomized study in general surgery","volume":"56","author":"Oestreicher","year":"1989","journal-title":"Helvetica Chirurgica Acta"},{"issue":"22","key":"10.1002\/14651858.CD012234.pub2-BIB0038|cit38","first-page":"1415","article-title":"Peritoneal lavage of diffuse peritonitis derived from perforated appendix","volume":"142","author":"Oleson","year":"1980","journal-title":"Ugeskrift for Laeger"},{"issue":"6","key":"10.1002\/14651858.CD012234.pub2-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1089\/sur.2015.020","article-title":"Effect of lavage with gentamicin vs clindamycin vs physiologic saline on drainage discharge of the axillary surgical bed after lymph node dissection","volume":"16","author":"Oller","year":"2015","journal-title":"Surgical Infections"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0041|cit40","first-page":"S52","article-title":"May peritoneal aspiration without irrigation decrease postoperative complication rate in perforated appendicitis?","volume":"29","author":"Ozlem","year":"2015","journal-title":"Surgical Endoscopy"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD012234.pub2-BIB0040|cit41","first-page":"23","article-title":"May peritoneal aspiration without irrigation decrease postoperative complication rate in perforated appendicitis?","volume":"50","author":"Ozlem","year":"2013","journal-title":"European Surgical Research"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0042|cit42","first-page":"179","article-title":"Cesarean prophylaxis: a comparison of cefamandole and cefazolin by both intravenous and lavage routes, and risk factors associated with endometritis","volume":"75","author":"Peterson","year":"1990","journal-title":"Obstetrics and Gynecology"},{"issue":"6","key":"10.1002\/14651858.CD012234.pub2-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1097\/01.sap.0000095656.18023.6b","article-title":"The effect of body mass index and wound irrigation on outcome after bilateral breast reduction","volume":"51","author":"Platt","year":"2003","journal-title":"Annals of Plastic Surgery"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/0002-9610(72)90332-7","article-title":"Irrigation of the peritoneal cavity with cephalothin","volume":"123","author":"Rambo","year":"1972","journal-title":"American Journal of Surgery"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0045|cit45","unstructured":"Ruiz-Tovar J Santos J Armananzas L Arroyo A Lopez A Alcaide MJ Evaluation of the effect of intraabdominal irrigation with normal saline and a with a gentamicin-clindamicin solution on the appearance of postoperative intrabdominal abscess and wound infection after elective surgery for colorectal cancer 24th European Congress on Surgical Infection; 2011 May 25-8; Le\u00f3n, Spain 2011 A15"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0046|cit46","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jamcollsurg.2011.10.014","article-title":"Effect of peritoneal lavage with clindamycin-gentamicin solution on infections after elective colorectal cancer surgery","volume":"214","author":"Ruiz-Tovar","year":"2012","journal-title":"Journal of the American College of Surgeons"},{"issue":"5","key":"10.1002\/14651858.CD012234.pub2-BIB0047|cit47","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/j.breast.2013.03.008","article-title":"Effect of gentamicin lavage of the axillary surgical bed after lymph node dissection on drainage discharge volume","volume":"22","author":"Ruiz-Tovar","year":"2013","journal-title":"Breast"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1089\/sur.2015.064","article-title":"Effect of peritoneal lavage with clindamycin-gentamicin solution during elective colorectal cancer surgery on the oncologic outcome","volume":"17","author":"Ruiz-Tovar","year":"2016","journal-title":"Surgical Infections"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0049|cit49","first-page":"357","article-title":"Effect of peritoneal lavage with clindamycin-gentamicin solution on post-operative pain and analytic acute-phase reactants after laparoscopic sleeve gastrectomy","volume":"3","author":"Ruiz-Tovar","journal-title":"Surgical Infections"},{"issue":"9","key":"10.1002\/14651858.CD012234.pub2-BIB0050|cit50","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1001\/archsurg.1990.01410210058008","article-title":"Peritoneal lavage in abdominal sepsis. A controlled clinical study","volume":"125","author":"Schein","year":"1990","journal-title":"Archives of Surgery"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0051|cit51","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1227\/NEU.0b013e3182195509","article-title":"Cerebral blood flow after surgery for unruptured cerebral aneurysms: effects of surgical manipulation and irrigation fluid","volume":"69","author":"Shimizu","year":"2011","journal-title":"Neurosurgery"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0052|cit52","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/BF02555014","article-title":"The effect of peritoneal lavage with tetracycline solution on postoperative infection. A prospective, randomized, clinical trial","volume":"29","author":"Silverman","year":"1986","journal-title":"Diseases of the Colon and Rectum"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0053|cit53","first-page":"48","article-title":"Efficacy of povidone-iodine irrigation in prevention of surgical wound infections","volume":"28","author":"Sindelar","year":"1977","journal-title":"Surgical Forum"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0054|cit54","first-page":"227","article-title":"Irrigation of subcutaneous tissue with povidone-iodine solution for prevention of surgical wound infections","volume":"148","author":"Sindelar","year":"1979","journal-title":"Surgery Gynecology and Obstetrics"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0055|cit55","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ijsu.2016.01.099","article-title":"Irrigation versus suction alone during laparoscopic appendectomy: a randomized controlled equivalence trial","volume":"28","author":"Snow","year":"2016","journal-title":"International Journal of Surgery"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0056|cit56","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1097\/SLA.0b013e31826a91e5","article-title":"Irrigation versus suction alone during laparoscopic appendectomy for perforated appendicitis","volume":"4","author":"Peter","year":"2012","journal-title":"Annals of Surgery"},{"issue":"7","key":"10.1002\/14651858.CD012234.pub2-BIB0057|cit57","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1007\/DCR.0b013e318211b83a","article-title":"Application of an electrolyzed strongly acidic aqueous solution before wound closure in colorectal surgery","volume":"54","author":"Takesue","year":"2011","journal-title":"Diseases of the Colon and Rectum"},{"issue":"6","key":"10.1002\/14651858.CD012234.pub2-BIB0058|cit58","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1002\/jhbp.222","article-title":"Randomized clinical trial of peritoneal lavage for preventing surgical site infection in elective liver surgery","volume":"22","author":"Tanaka","year":"2015","journal-title":"Journal of Hepato-biliary-pancreatic Sciences"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0059|cit59","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1002\/bjs.1800650206","article-title":"Wound infection in emergency appendicectomy: a prospective trial with tropical ampicillin and antiseptic solution irrigation","volume":"65","author":"Tanphiphat","year":"1978","journal-title":"British Journal of Surgery"},{"issue":"4","key":"10.1002\/14651858.CD012234.pub2-BIB0060|cit60","doi-asserted-by":"crossref","first-page":"651","DOI":"10.3109\/14767058.2015.1015415","article-title":"The effect of peritoneal cavity saline irrigation at cesarean delivery on maternal morbidity and gastrointestinal system outcomes","volume":"29","author":"Temizkan","year":"2016","journal-title":"Journal of Maternal-Fetal & Neonatal Medicine"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0061|cit61","first-page":"96","article-title":"Betadine irrigation following appendicectomy - a randomized prospective trial","volume":"75","author":"Tighe","year":"1982","journal-title":"Irish Medical Journal"},{"issue":"8","key":"10.1002\/14651858.CD012234.pub2-BIB0062|cit62","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1093\/humrep\/der135","article-title":"Gynaecological endoscopic evaluation of 4% icodextrin solution: a European, multicentre, double-blind, randomized study of the efficacy and safety in the reduction of de novo adhesions after laparoscopic gynaecological surgery","volume":"26","author":"Trew","year":"2011","journal-title":"Human Reproduction"},{"issue":"Suppl A","key":"10.1002\/14651858.CD012234.pub2-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0195-6701(85)80051-7","article-title":"Antiseptic vs. saline lavage in purulent and faecal peritonitis","volume":"6","author":"Vallance","year":"1985","journal-title":"Journal of Hospital Infection"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0064|cit64","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1097\/AOG.0b013e3182460d09","article-title":"Intra-abdominal irrigation at cesarean delivery: a randomized controlled trial","volume":"119","author":"Viney","year":"2012","journal-title":"Obstetrics and Gynecology"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0065|cit65","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s11255-005-8440-3","article-title":"Prevention of pain and infective complications after transrectal prostate biopsy: a prospective study","volume":"38","author":"Akay","year":"2006","journal-title":"International Urology and Nephrology"},{"issue":"8","key":"10.1002\/14651858.CD012234.pub2-BIB0066|cit66","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1007\/s00268-011-1139-y","article-title":"Prospective, controlled, randomized study of intraoperative colonic lavage versus stent placement in obstructive left-sided colonic cancer","volume":"35","author":"Alcantara","year":"2011","journal-title":"World Journal of Surgery"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0067|cit67","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.ijgo.2006.03.030","article-title":"Saline irrigation and wound infection in abdominal gynecologic surgery","volume":"94","author":"Al-Ramahi","year":"2006","journal-title":"International Journal of Gynaecology and Obstetrics"},{"issue":"7","key":"10.1002\/14651858.CD012234.pub2-BIB0068|cit68","first-page":"1415","article-title":"Comparison of soap and antibiotic solutions for irrigation of lower-limb open fracture wounds: a prospective, randomized study","volume":"87","author":"Anglen","year":"2005","journal-title":"Journal of Bone and Joint Surgery"},{"issue":"6","key":"10.1002\/14651858.CD012234.pub2-BIB0069|cit69","first-page":"167","article-title":"Prevention of projectile and aerosol contamination during pulsatile lavage irrigation using a wound irrigation bag","volume":"20","author":"Angobaldo","year":"2008","journal-title":"Wounds"},{"issue":"6","key":"10.1002\/14651858.CD012234.pub2-BIB0070|cit70","first-page":"201","article-title":"Randomized prospective study on antibiotic prophylaxis compared with lavage of the surgical wound in unperforated appendicitis","volume":"103","author":"Badia","year":"1994","journal-title":"Medicina Clinica"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0071|cit71","first-page":"1","article-title":"A randomized, blinded, multicenter trial of a gentamicin vancomycin gel (DFA-02) in patients undergoing abdominal surgery","volume":"10","author":"Bennett-Guerrero","year":"2016","journal-title":"American Journal of Surgery"},{"issue":"11","key":"10.1002\/14651858.CD012234.pub2-BIB0072|cit72","first-page":"685","article-title":"Prophylactic irrigation of wounds with neomycin (Nebacetin). Controlled study of the effect in orthopedic surgical operations","volume":"142","author":"Bertheussen","year":"1980","journal-title":"Ugeskrift for Laeger"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0073|cit73","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1258\/004947506775598923","article-title":"Wound infection after metronidazole infiltration","volume":"36","author":"Bhargava","year":"2006","journal-title":"Tropical Doctor"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0074|cit74","first-page":"830","article-title":"Comparison of intravenous cefoxitin prophylaxis with intraoperative cefoxitin irrigation for the prevention of post-cesarean-section endometritis","volume":"29","author":"Boothby","year":"1984","journal-title":"Journal of Reproductive Medicine"},{"issue":"4","key":"10.1002\/14651858.CD012234.pub2-BIB0075|cit75","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1034\/j.1399-6576.2000.440424-6.x","article-title":"Postoperative analgesia with intramuscular bupivacaine wound irrigation in renal surgery","volume":"44","author":"Cherian","year":"2000","journal-title":"Acta Anaesthesiologica Scandinavica"},{"issue":"11","key":"10.1002\/14651858.CD012234.pub2-BIB0076|cit76","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1016\/S0196-0644(05)81903-1","article-title":"Comparison of a new pressurized saline canister versus syringe irrigation for laceration cleansing in the emergency department","volume":"21","author":"Chisholm","year":"1992","journal-title":"Annals of Emergency Medicine"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0077|cit77","first-page":"15","article-title":"Antibiotic prophylaxis in cesarean section. Comparison of intrauterine lavage and intravenous administration","volume":"31","author":"Donnenfeld","year":"1986","journal-title":"Journal of Reproductive Medicine"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0078|cit78","first-page":"153","article-title":"Perforation of acutely inflamed appendix treated intraperitoneal cefazoline","volume":"27","author":"Ducharme","year":"1986","journal-title":"Chirurgie p\u00e9diatrique"},{"issue":"10","key":"10.1002\/14651858.CD012234.pub2-BIB0079|cit79","first-page":"A125","article-title":"Pacemaker pocket irrigation with antibiotics has no role in infection prevention","volume":"53","author":"Dwivedi","year":"2009","journal-title":"Journal of the American College of Cardiology"},{"issue":"9","key":"10.1002\/14651858.CD012234.pub2-BIB0080|cit80","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1002\/bjs.1800560911","article-title":"The place of antibiotics in colonic surgery: a clinical study","volume":"56","author":"Everett","year":"1969","journal-title":"British Journal of Surgery"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0081|cit81","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/1471-2474-11-85","article-title":"Fluid lavage of open wounds (FLOW): design and rationale for a large, multicenter collaborative 2 x 3 factorial trial of irrigating pressures and solutions in patients with open fractures","volume":"11","author":"Bhandari","year":"2010","journal-title":"BMC Musculoskeletal Disorders"},{"issue":"27","key":"10.1002\/14651858.CD012234.pub2-BIB0082|cit82","doi-asserted-by":"crossref","first-page":"2629","DOI":"10.1056\/NEJMoa1508502","article-title":"A trial of wound irrigation in the initial management of open fracture wounds","volume":"373","author":"Bhandari","year":"2015","journal-title":"New England Journal of Medicine"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0083|cit83","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1097\/TA.0b013e3181f6f2e8","article-title":"Fluid lavage of open wounds (FLOW): a multicenter, blinded, factorial pilot trial comparing alternative irrigating solutions and pressures in patients with open fractures","volume":"71","author":"Petrisor","year":"2011","journal-title":"Journal of Trauma Injury Infection & Critical Care"},{"issue":"18","key":"10.1002\/14651858.CD012234.pub2-BIB0084|cit84","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1097\/00007632-199909150-00016","article-title":"Postoperative lumbar microdiscectomy pain. Minimalization by irrigation and cooling","volume":"24","author":"Fountas","year":"1999","journal-title":"Spine"},{"issue":"4","key":"10.1002\/14651858.CD012234.pub2-BIB0085|cit85","first-page":"686","article-title":"Topical versus systemic cephalosporin administration in elective biliary operations","volume":"96","author":"Freischlag","year":"1984","journal-title":"Surgery"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0086|cit86","first-page":"744","article-title":"Ineffectiveness of povidone-iodine irrigation of abdominal incisions","volume":"55","author":"Galle","year":"1980","journal-title":"Obstetrics and Gynecology"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0087|cit87","doi-asserted-by":"crossref","first-page":"43","DOI":"10.4103\/2278-9596.117121","article-title":"Evaluation of intraoperative peritoneal lavage with super-oxidized solution and normal saline in acute peritonitis","volume":"3","author":"Garg","year":"2013","journal-title":"Archives of International Surgery"},{"issue":"Suppl 8","key":"10.1002\/14651858.CD012234.pub2-BIB0088|cit88","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.arth.2013.03.038","article-title":"A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty","volume":"28","author":"Georgiadis","year":"2013","journal-title":"Journal of Arthroplasty"},{"issue":"4","key":"10.1002\/14651858.CD012234.pub2-BIB0089|cit89","doi-asserted-by":"crossref","first-page":"724","DOI":"10.3171\/jns.1984.60.4.0724","article-title":"Antibiotic prophylaxis in neurosurgery. A randomized controlled trial","volume":"60","author":"Geraghty","year":"1984","journal-title":"Journal of Neurosurgery"},{"issue":"9","key":"10.1002\/14651858.CD012234.pub2-BIB0090|cit90","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1016\/j.injury.2016.05.031","article-title":"Randomized, controlled trial of povidone-iodine to reduce simple traumatic wound infections in the emergency department","volume":"47","author":"Ghafouri","year":"2016","journal-title":"Injury"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0091|cit91","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.wndm.2016.08.001","article-title":"Is 1% povidone-iodine solution superior to normal saline for simple traumatic wound irrigation?","volume":"15","author":"Ghafouri","year":"2016","journal-title":"Wound Medicine"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0092|cit92","doi-asserted-by":"crossref","first-page":"1188-91","DOI":"10.1067\/mob.2002.122984","article-title":"A randomized trial of postoperative wound irrigation with local anesthetic for pain after cesarean delivery","volume":"186","author":"Givens","year":"2002","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0093|cit93","first-page":"545-8","article-title":"Effect of irrigation or intravenous antibiotic prophylaxis on infectious morbidity at cesarean section","volume":"67","author":"Gonen","year":"1986","journal-title":"Obstetrics and Gynecology"},{"issue":"4","key":"10.1002\/14651858.CD012234.pub2-BIB0094|cit94","first-page":"64-6, 68","article-title":"Comparison of wound irrigation and tangential hydrodissection in bacterial clearance of contaminated wounds: results of a randomized, controlled clinical study","volume":"53","author":"Granick","year":"2007","journal-title":"Ostomy\/wound Management"},{"issue":"4","key":"10.1002\/14651858.CD012234.pub2-BIB0095|cit95","doi-asserted-by":"crossref","first-page":"e12732","DOI":"10.5812\/ircmj.12732","article-title":"Irrigation of abdomen with imipenem solution decreases surgical site infections in patients with perforated appendicitis: a randomized clinical trial","volume":"16","author":"Hesami","year":"2014","journal-title":"Iranian Red Crescent Medical Journal"},{"issue":"6","key":"10.1002\/14651858.CD012234.pub2-BIB0096|cit96","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1213\/00000539-199912000-00027","article-title":"Wound infiltration and drain lavage with ropivacaine after major shoulder surgery","volume":"89","author":"Horn","year":"1999","journal-title":"Anesthesia and Analgesia"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0097|cit97","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1001\/archsurg.1982.01380260075013","article-title":"Generalized peritonitis. To irrigate or not to irrigate the abdominal cavity","volume":"117","author":"Hunt","year":"1982","journal-title":"Archives of Surgery"},{"issue":"4","key":"10.1002\/14651858.CD012234.pub2-BIB0098|cit98","first-page":"165","article-title":"Topical antibiotics for prophylaxis against umbilical wound infection in laparoscopic cholecystectomy","volume":"8","author":"Iqbal","year":"1998","journal-title":"Journal of the College of Physicians and Surgeons - Pakistan"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0099|cit99","first-page":"160","article-title":"Effect of povidone-iodine irrigation on post appendectomy wound infection: randomized control trial","volume":"29","author":"Iqbal","year":"2015","journal-title":"Journal of Postgraduate Medical Institute"},{"issue":"6 (Suppl)","key":"10.1002\/14651858.CD012234.pub2-BIB0100|cit100","doi-asserted-by":"crossref","first-page":"S96","DOI":"10.1016\/j.ajog.2006.10.314","article-title":"Does saline irrigation in the peritoneal cavity at the time of a non-scheduled cesarean section reduce maternal morbidity","volume":"195","author":"Keblawi","year":"2006","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"7","key":"10.1002\/14651858.CD012234.pub2-BIB0101|cit101","first-page":"527","article-title":"Effect of intrauterine antibiotic lavage after cesarean birth on postoperative morbidity","volume":"30","author":"Kellum","year":"1985","journal-title":"Journal of Reproductive Medicine"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0102|cit102","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0003-4975(92)91337-9","article-title":"Effects of shaving methods and intraoperative irrigation on suppurative mediastinitis after bypass operations","volume":"53","author":"Ko","year":"1992","journal-title":"Annals of Thoracic Surgery"},{"issue":"4","key":"10.1002\/14651858.CD012234.pub2-BIB0103|cit103","first-page":"186","article-title":"The effect of povidone-iodine on postoperative wound infection in abdominal surgery","volume":"33","author":"Kothuis","year":"1981","journal-title":"The Netherlands Journal of Surgery"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0104|cit104","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1002\/bjs.1800731205","article-title":"Combined topical povidone-iodine and systemic antibiotics in postappendicectomy wound sepsis","volume":"73","author":"Lau","year":"1986","journal-title":"British Journal of Surgery"},{"issue":"10","key":"10.1002\/14651858.CD012234.pub2-BIB0105|cit105","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1097\/00007611-198610000-00013","article-title":"Mezlocillin prophylaxis against infection after cesarean section: a comparison of techniques","volume":"79","author":"Lavery","year":"1986","journal-title":"Southern Medical Journal"},{"issue":"5","key":"10.1002\/14651858.CD012234.pub2-BIB0106|cit106","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/bjs.1800600508","article-title":"The effect of topical ampicillin on wound-infection rate after cholecystectomy","volume":"60","author":"Logan","year":"1973","journal-title":"British Journal of Surgery"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0107|cit107","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0735-6757(87)90121-5","article-title":"Wound infection following high-pressure syringe and needle irrigation","volume":"5","author":"Longmire","year":"1987","journal-title":"American Journal of Emergency Medicine"},{"issue":"88","key":"10.1002\/14651858.CD012234.pub2-BIB0108|cit108","first-page":"21","article-title":"The effect of local Gentamicin solution on episiotomy healing: a randomized controlled clinical trial","volume":"16","author":"Makvandi","year":"2014","journal-title":"Iranian Journal of Obstetrics, Gynecology and Infertility"},{"issue":"Suppl","key":"10.1002\/14651858.CD012234.pub2-BIB0109|cit109","first-page":"204","article-title":"Evaluation of three techniques for cleaning infected surgical site with physiological serum","volume":"11","author":"Martins","year":"2012","journal-title":"Ciencia, Cuidado e Saude"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0110|cit110","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1515\/jpme.1992.20.3.177","article-title":"A comparison of postoperative morbidity following prophylactic antibiotic administration by combined irrigation and intravenous route or by intravenous route alone during cesarean section","volume":"20","author":"Mathelier","year":"1992","journal-title":"Journal of Perinatal Medicine"},{"issue":"6","key":"10.1002\/14651858.CD012234.pub2-BIB0111|cit111","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1097\/AAP.0000000000000496","article-title":"Effect of topical morphine on acute and chronic postmastectomy pain: what is the optimum dose?","volume":"41","author":"Mohamed","year":"2017","journal-title":"Regional Anesthesia and Pain Medicine"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0112|cit112","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0735-6757(98)90062-6","article-title":"Wound infection rate and irrigation pressure of two potential new wound irrigation devices: the port and the cap","volume":"16","author":"Morse","year":"1998","journal-title":"American Journal of Emergency Medicine"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0113|cit113","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1001\/jama.1968.03140210041010","article-title":"A study of neomycin instillation into orthopedic surgical wounds","volume":"204","author":"Nachamie","year":"1968","journal-title":"JAMA"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0114|cit114","first-page":"20","article-title":"Washing with or without chloramphenicol in the treatment of peritonitis: a prospective, clinical trial","volume":"99","author":"Nomikos","year":"1986","journal-title":"Surgery"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0115|cit115","first-page":"73","article-title":"Clinical evaluation of peritoneal irrigation with antibiotic solution","volume":"62","author":"Noon","year":"1967","journal-title":"Surgery"},{"issue":"5","key":"10.1002\/14651858.CD012234.pub2-BIB0116|cit116","first-page":"518","article-title":"The role of topical antibiotics in 'high-risk' biliary surgery","volume":"91","author":"Pitt","year":"1982","journal-title":"Surgery"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0117|cit117","first-page":"754","article-title":"Pulsating spooler for cleaning contaminated and infected wounds (Jet Lavage)","volume":"56","author":"Plaumann","year":"1985","journal-title":"Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen"},{"issue":"6","key":"10.1002\/14651858.CD012234.pub2-BIB0118|cit118","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1093\/oxfordjournals.bja.a013583","article-title":"Does wound irrigation with triamcinolone reduce pain after surgery to the lumbar spine?","volume":"84","author":"Pobereskin","year":"2000","journal-title":"British Journal of Anaesthesia"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0119|cit119","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1002\/bjs.1800650204","article-title":"The bacteriology of primary wound sepsis in potentially contaminated abdominal operations: the effect of irrigation, povidone-iodine and Cephaloridine on the sepsis rate assessed in a clinical trial","volume":"65","author":"Pollock","year":"1978","journal-title":"British Journal of Surgery"},{"issue":"5","key":"10.1002\/14651858.CD012234.pub2-BIB0120|cit120","first-page":"426","article-title":"Povidone-iodine wound irrigation and wound sepsis","volume":"157","author":"Rogers","year":"1983","journal-title":"Surgery, Gynecology & Obstetrics"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0121|cit121","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0735-6757(85)90005-1","article-title":"The use of antibiotics in the initial management of recent dog-bite wounds","volume":"3","author":"Rosen","year":"1985","journal-title":"American Journal of Emergency Medicine"},{"issue":"4","key":"10.1002\/14651858.CD012234.pub2-BIB0122|cit122","first-page":"315","article-title":"Value of subcutaneous and intraperitoneal antibiotics in reducing infection in clean contaminated operations of the colon","volume":"167","author":"Salvati","year":"1988","journal-title":"Surgery, Gynecology & Obstetrics"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0123|cit123","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/S0002-9610(88)80728-1","article-title":"Topical antibiotics in the high-risk biliary surgical patient: a prospective, randomized study","volume":"155","author":"Sarr","year":"1988","journal-title":"American Journal of Surgery"},{"issue":"8","key":"10.1002\/14651858.CD012234.pub2-BIB0124|cit124","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1016\/j.arth.2014.02.031","article-title":"Comparing efficacy of three methods of tranexamic acid administration in reducing hemoglobin drop following total knee arthroplasty","volume":"29","author":"Sarzaeem","year":"2014","journal-title":"Journal of Arthroplasty"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0125|cit125","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1177\/014107688607900304","article-title":"Single-dose antibiotic prophylaxis of abdominal surgical wound infection: a trial of preoperative latamoxef against peroperative tetracycline lavage","volume":"79","author":"Sauven","year":"1986","journal-title":"Journal of the Royal Society of Medicine"},{"issue":"7","key":"10.1002\/14651858.CD012234.pub2-BIB0126|cit126","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1002\/bjs.1800720717","article-title":"Influence of rectal washout on bacterial counts in the rectal stump","volume":"72","author":"Scammell","year":"1985","journal-title":"British Journal of Surgery"},{"issue":"Suppl 2","key":"10.1002\/14651858.CD012234.pub2-BIB0127|cit127","first-page":"199","article-title":"Prospective multicenter comparative study of the management of peritonitis. Quality assurance in severe intra-abdominal infection","volume":"125","author":"Scheuerlein","year":"2000","journal-title":"Zentralblatt fur Chirurgie"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0128|cit128","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/S0002-9610(05)80267-3","article-title":"Combined topical and systemic antibiotic prophylaxis in acute appendicitis","volume":"159","author":"Seco","year":"1990","journal-title":"American Journal of Surgery"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0129|cit129","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0195-6701(86)90125-8","article-title":"Randomized clinical trial of intra-operative antimicrobial prophylaxis of infection after neurosurgical procedures","volume":"8","author":"Shapiro","year":"1986","journal-title":"Journal of Hospital Infection"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0130|cit130","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/S0022-3468(76)80191-1","article-title":"Irrigation of the peritoneal cavity for appendicitis in children: a double-blind study","volume":"11","author":"Sherman","year":"1976","journal-title":"Journal of Pediatric Surgery"},{"issue":"Suppl A","key":"10.1002\/14651858.CD012234.pub2-BIB0131|cit131","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0195-6701(85)80054-2","article-title":"Randomised trial of intraperitoneal irrigation with low molecular weight povidone-iodine solution to reduce intra-abdominal infectious complications","volume":"6","author":"Sindelar","year":"1985","journal-title":"Journal of Hospital Infection"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0132|cit132","first-page":"92","article-title":"Role of intra-operative wound lavage in post-operative wound infection","volume":"81","author":"Sood","year":"1985","journal-title":"Indian Journal of Medical Research"},{"issue":"Suppl","key":"10.1002\/14651858.CD012234.pub2-BIB0133|cit133","first-page":"S86","article-title":"Effect of irrigation with chlorhexidine gluconate on surgical site infections in pilonidal disease","volume":"1","author":"Terzi","year":"2015","journal-title":"European Surgery"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0134|cit134","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/BF00311528","article-title":"Peritoneal lavage versus drainage for perforated appendicitis in children","volume":"25","author":"Toki","year":"1995","journal-title":"Surgery Today"},{"issue":"5 (Suppl 1)","key":"10.1002\/14651858.CD012234.pub2-BIB0135|cit135","doi-asserted-by":"crossref","first-page":"S146","DOI":"10.1197\/j.aem.2007.03.1115","article-title":"Tap water is equally safe and effective as sterile normal saline for wound irrigation; a double blind, randomized, controlled, prospective clinical trial","volume":"14","author":"Weiss","year":"2007","journal-title":"Society for Academic Emergency Medicine"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0136|cit136","doi-asserted-by":"crossref","first-page":"e001504","DOI":"10.1136\/bmjopen-2012-001504","article-title":"Water is a safe and effective alternative to sterile normal saline for wound irrigation prior to suturing: a prospective, double-blind, randomised, controlled clinical trial","volume":"3","author":"Weiss","year":"2013","journal-title":"BMJ Open"},{"issue":"6","key":"10.1002\/14651858.CD012234.pub2-BIB0137|cit137","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1097\/PRS.0b013e31818d5899","article-title":"Pharmacokinetics of topical and intravenous cefazolin in patients with clean surgical wounds","volume":"122","author":"White","year":"2008","journal-title":"Plastic and Reconstructive Surgery"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0138|cit138","first-page":"73","article-title":"Prevention of post-operative infection by using antibiotics of 217 cases of cesarean section","volume":"27","author":"Wu","year":"1992","journal-title":"Chung-Hua fu chan ko tsa chih [Chinese Journal of Obstetrics & Gynecology]"},{"issue":"14","key":"10.1002\/14651858.CD012234.pub2-BIB0139|cit139","first-page":"1088","article-title":"Management of the perineal wounds after abdominalperineal resection: simple drainage only or with continuous irrigation?","volume":"48","author":"Xiao","year":"2010","journal-title":"Zhonghua wai ke za zhi [Chinese Journal of Surgery]"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0140|cit140","first-page":"142","article-title":"Evaluation of peripheral morphine analgesia for lumpectomy and axillary node dissection: a randomized, double-blind, placebo-controlled study","volume":"24","author":"Yarussi","year":"1999","journal-title":"Regional Anesthesia and Pain Medicine"},{"issue":"4","key":"10.1002\/14651858.CD012234.pub2-BIB0141|cit141","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s10397-015-0897-1","article-title":"Extensive peritoneal lavage decreases postoperative C-reactive protein concentrations: A RCT","volume":"12","author":"Cicco","year":"2015","journal-title":"Gynecological Surgery"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0142|cit142","first-page":"22","article-title":"The effect of wound irrigation on bacterial contamination of suction instrumentation during joint prosthesis surgery","volume":"5","author":"Kok","year":"1998","journal-title":"Nederlands Tijdschrift voor Orthopaedie"},{"issue":"Suppl 282","key":"10.1002\/14651858.CD012234.pub2-BIB0143|cit143","first-page":"14","article-title":"The effect of wound irrigation on bacterial contamination of suction instruments in prosthetic surgery","volume":"69","author":"Kok","year":"1998","journal-title":"Acta Orthopaedica Scandinavica"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0144|cit144","doi-asserted-by":"crossref","first-page":"269","DOI":"10.29333\/ejgm\/82867","article-title":"Rifamycin SV application to subcutaneous tissue for prevention of post-cesarean surgical site infection","volume":"7","author":"Kosu\u015f","year":"2010","journal-title":"European Journal of General Medicine"},{"issue":"9","key":"10.1002\/14651858.CD012234.pub2-BIB0145|cit145","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1007\/s00402-011-1291-8","article-title":"Comparison of a low-pressure and a high-pressure pulsatile lavage during debridement for orthopaedic implant infection","volume":"131","author":"Munoz-Mahamud","year":"2011","journal-title":"Archives of Orthopaedic and Trauma Surgery"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD012234.pub2-BIB0146|cit146","first-page":"48","article-title":"Surgical wound decontamination with chlorhexidine jet lavage","volume":"81","author":"Taylor","year":"1999","journal-title":"Journal of Bone and Joint Surgery"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0147|cit147","unstructured":"ACTRN12610000423011 Does peritoneal lavage influence the rate of complications in paediatric laparoscopic appendicectomy? A prospective randomised clinical trial apps.who.int\/trialsearch\/Trial2.aspx?TrialID=ACTRN12610000423011"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0148|cit148","unstructured":"NCT01175044 Dilute Betadine lavage in the prevention of postoperative infection clinicaltrials.gov\/ct2\/show\/NCT01175044"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0149|cit149","unstructured":"NCT02186457 Antibiotic irrigation for pancreatoduodenectomy clinicaltrials.gov\/ct2\/show\/NCT02186457"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0150|cit150","unstructured":"NCT02395614 Surgical site infection with 0.05% chlorhexidine (CHG) compared with triple antibiotic irrigation clinicaltrials.gov\/ct2\/show\/study\/NCT02395614"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0151|cit151","unstructured":"NCT02527512 Bacterial contamination: iodine vs saline irrigation in pediatric spine surgery clinicaltrials.gov\/ct2\/show\/NCT02527512"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0152|cit152","unstructured":"NCT02714023 Water and saline head-to-head in the blinded evaluation study trial (WASHITBEST) clinicaltrials.gov\/ct2\/show\/NCT02714023"},{"issue":"9761","key":"10.1002\/14651858.CD012234.pub2-BIB0153|cit153","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S0140-6736(10)61458-4","article-title":"Burden of endemic health-care-associated infection in developing countries: systematic review and meta-analysis","volume":"377","author":"Allegranzi","year":"2010","journal-title":"Lancet"},{"issue":"9","key":"10.1002\/14651858.CD012234.pub2-BIB0154|cit154","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1086\/590124","article-title":"Poor functional status as a risk factor for surgical site infection due to methicillin-resistant staphylococcus aureus","volume":"29","author":"Anderson","year":"2013","journal-title":"Infection Control and Hospital Epidemiology"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0155|cit155","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.jhin.2009.03.005","article-title":"Reducing surgical site infection incidence through a network: results from the French ISO-RAISIN surveillance system","volume":"72","author":"Astagneau","year":"2009","journal-title":"Journal of Hospital Infection"},{"issue":"6825","key":"10.1002\/14651858.CD012234.pub2-BIB0156|cit156","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1136\/bmj.304.6825.469","article-title":"Community surveillance of complications after hernia surgery","volume":"304","author":"Bailey","year":"1992","journal-title":"BMJ"},{"issue":"5","key":"10.1002\/14651858.CD012234.pub2-BIB0157|cit157","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.ajic.2014.01.012","article-title":"Surgical wound irrigation: a call for evidence-based standardization of practice","volume":"42","author":"Barnes","year":"2014","journal-title":"American Journal of Infection Control"},{"issue":"22","key":"10.1002\/14651858.CD012234.pub2-BIB0158|cit158","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta5220","article-title":"The measurement and monitoring of surgical adverse events","volume":"5","author":"Bruce","year":"2001","journal-title":"Health Technology Assessment"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0159|cit159","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1245\/s10434-010-0923-5","article-title":"Characteristics and outcomes of methicillin-resistant staphylococcus aureus surgical-site infections in patients with cancer: a case-control study","volume":"17","author":"Chemaly","year":"2010","journal-title":"Annals of Surgical Oncology"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0160|cit160","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.jhin.2004.10.019","article-title":"Adverse impact of surgical site infections in English hospitals","volume":"60","author":"Coello","year":"2005","journal-title":"Journal of Hospital Infection"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0161|cit161","unstructured":"De Jonge SW Boldingh QJJ Solomkin JS Allegranzi B Egger M Dellinger EP Systematic review and meta-analysis of randomized controlled trials evaluating prophylactic intra-operative wound irrigation for the prevention of surgical site infections Surgical Infections 10.1089\/sur.2016.272"},{"issue":"5","key":"10.1002\/14651858.CD012234.pub2-BIB0162|cit162","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.ajic.2008.12.010","article-title":"Surgical site infection: incidence and impact on hospital utilization and treatment costs","volume":"37","author":"Lissovoy","year":"2009","journal-title":"American Journal of Infection Control"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0163|cit163","unstructured":"Deeks JJ Higgins JP Altman DG editor(s) Chapter 9: Analysing data and undertaking meta-analyses. In: Higgins JP, Green S, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from handbook.cochrane.org"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0164|cit164","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1302\/0301-620X.90B6.20194","article-title":"Early infection after hip fracture surgery: risk factors, costs and outcome","volume":"90","author":"Edwards","year":"2008","journal-title":"Journal of Bone and Joint Surgery"},{"issue":"10","key":"10.1002\/14651858.CD012234.pub2-BIB0165|cit165","first-page":"1588","article-title":"Intra-abdominal saline irrigation at cesarean section: a systematic review and meta-analysis","volume":"29","author":"Eke","year":"2016","journal-title":"The Journal of Maternal-Fetal & Neonatal Medicine"},{"issue":"11","key":"10.1002\/14651858.CD012234.pub2-BIB0166|cit166","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1002\/bjs.7212","article-title":"Meta-analysis of intraoperative povidone-iodine application to prevent surgical-site infection","volume":"97","author":"Fournel","year":"2010","journal-title":"British Journal of Surgery"},{"issue":"30","key":"10.1002\/14651858.CD012234.pub2-BIB0167|cit167","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta15300","article-title":"Identification of risk factors by systematic review and development of risk-adjusted models for surgical site infection","volume":"15","author":"Gibbons","year":"2011","journal-title":"Health Technology Assessment"},{"issue":"4","key":"10.1002\/14651858.CD012234.pub2-BIB0168|cit168","first-page":"259","article-title":"Guideline for prevention of surgical site infection 1999","volume":"20","author":"Hospital Infection Control Practices Advisory Committee (HICPAC)","year":"1999","journal-title":"Infection Control and Hospital Epidemiology"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0169|cit169","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0170|cit170","unstructured":"Higgins JP Altman DG Sterne JA editor(s) Chapter 8: Assessing risk of bias in included studies. In: Higgins JP, Green S, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from handbook.cochrane.org"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0171|cit171","unstructured":"Higgins JP Deeks JJ Altman DG editor(s) Chapter 16: Special topics in statistics. In: Higgins JP, Green S, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from handbook.cochrane.org"},{"issue":"10","key":"10.1002\/14651858.CD012234.pub2-BIB0172|cit172","doi-asserted-by":"crossref","first-page":"606","DOI":"10.2307\/30148464","article-title":"CDC definitions of nosocomial surgical site infections 1992: a modification of CDC definitions of surgical wound infections","volume":"13","author":"Horan","year":"1992","journal-title":"Infection Control and Hospital Epidemiology"},{"issue":"5","key":"10.1002\/14651858.CD012234.pub2-BIB0173|cit173","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.ajic.2008.03.002","article-title":"CDC\/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting","volume":"36","author":"Horan","year":"2008","journal-title":"American Journal of Infection Control"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0174|cit174","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jhin.2013.09.012","article-title":"Clinical and economic burden of surgical site infection (SSI) and predicted financial consequences of elimination of SSI from an English hospital","volume":"86","author":"Jenks","year":"2014","journal-title":"Journal of Hospital Infection"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0175|cit175","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1177\/0962280210392008","article-title":"Performance of statistical methods for meta-analysis when true study effects are non-normally distributed","volume":"21","author":"Kontopantelis","year":"2012","journal-title":"Statistical Methods Methodology Research"},{"issue":"7","key":"10.1002\/14651858.CD012234.pub2-BIB0176|cit176","doi-asserted-by":"crossref","first-page":"e69930","DOI":"10.1371\/journal.pone.0069930","article-title":"A re-analysis of the Cochrane Library data: the dangers of unobserved heterogeneity in meta-analysis","volume":"8","author":"Kontopantelis","year":"2013","journal-title":"PLoS One"},{"issue":"12","key":"10.1002\/14651858.CD012234.pub2-BIB0177|cit177","doi-asserted-by":"crossref","first-page":"e83743","DOI":"10.1371\/journal.pone.0083743","article-title":"A systematic review of risk factors associated with surgical site infections among surgical patients","volume":"8","author":"Korol","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0178|cit178","unstructured":"Lefebvre C Manheimer E Glanville J Chapter 6: Searching for studies. In: Higgins JP, Green S, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from handbook.cochrane.org"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0179|cit179","doi-asserted-by":"crossref","first-page":"b2700","DOI":"10.1136\/bmj.b2700","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration","volume":"339","author":"Liberati","year":"2009","journal-title":"BMJ"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0180|cit180","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s00423-015-1279-x","article-title":"Intra-operative wound irrigation to reduce surgical site infections after abdominal surgery: a systematic review and meta-analysis","volume":"400","author":"Mueller","year":"2015","journal-title":"Langenbecks Archives of Surgery"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0181|cit181","unstructured":"National Institute for Health and Care Excellence (NICE) Surgical site infections: prevention and treatment. NICE guidelines [CG74]. October 2008 www.nice.org.uk\/guidance\/cg74"},{"issue":"1","key":"10.1002\/14651858.CD012234.pub2-BIB0182|cit182","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1590\/S0080-62342008000100026","article-title":"Use of topic iodine in acute wounds","volume":"42","author":"Oliveira","year":"2008","journal-title":"Revista da Escola de Enfermagem da USP"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0183|cit183","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/1471-2334-7-112","article-title":"Superficial and deep sternal wound infection after more than 9000 coronary artery bypass graft (CABG): incidence, risk factors and mortality","volume":"7","author":"Omran","year":"2007","journal-title":"BMC Infectious Diseases"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0184|cit184","doi-asserted-by":"crossref","first-page":"196","DOI":"10.3201\/eid0902.020232","article-title":"Health and economic impact of surgical site infections diagnosed after hospital discharge","volume":"9","author":"Perencevich","year":"2003","journal-title":"Emerging Infectious Diseases"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0185|cit185","unstructured":"Public Health England Surveillance of surgical site infections in NHS hospitals in England: 2013 to 2014 www.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/386927\/SSI_report_2013_14_final__3_.pdf"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0186|cit186","unstructured":"Nordic Cochrane Centre, The Cochrane Collaboration Review Manager 5 (RevMan 5) 2014"},{"issue":"6","key":"10.1002\/14651858.CD012234.pub2-BIB0187|cit187","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1302\/0301-620X.87B6.15121","article-title":"Infection of the surgical site after arthroplasty of the hip","volume":"87","author":"Ridgeway","year":"2005","journal-title":"The Journal of Bone and Joint Surgery"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0188|cit188","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/iwj.12088","article-title":"Determining risk factors for surgical wound dehiscence: a literature review","volume":"12","author":"Sandy-Hodgetts","year":"2015","journal-title":"International Wound Journal"},{"issue":"2","key":"10.1002\/14651858.CD012234.pub2-BIB0189|cit189","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/j.1524-475X.2011.00673.x","article-title":"Dynamic reciprocity in the wound microenvironment","volume":"19","author":"Schultz","year":"2011","journal-title":"Wound Repair and Regeneration"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0190|cit190","unstructured":"Sch\u00fcnemann HJ Oxman AD Higgins JP Vist GE Glasziou P Guyatt GH Chapter 11: Presenting results and 'Summary of findings' tables. In: Higgins JP, Green S, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from handbook.cochrane.org"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0191|cit191","unstructured":"Sch\u00fcnemann HJ Oxman AD Higgins JP Deeks JJ Glasziou P Guyatt GH Chapter 12: Interpreting results and drawing conclusions. In: Higgins JP, Green S, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from handbook.cochrane.org"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0192|cit192","unstructured":"Scottish Intercollegiate Guidelines Network (SIGN) Search filters www.sign.ac.uk\/methodology\/filters.html#random"},{"issue":"10","key":"10.1002\/14651858.CD012234.pub2-BIB0193|cit193","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007482.pub3","article-title":"Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section","author":"Smaill","year":"2014","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"3","key":"10.1002\/14651858.CD012234.pub2-BIB0194|cit194","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.jhin.2008.04.020","article-title":"Four country healthcare associated infection prevalence survey 2006: overview of the results","volume":"69","author":"Smyth","year":"2008","journal-title":"The Journal of Hospital Infection"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0195|cit195","unstructured":"Sterne JA Egger M Moher D Chapter 10: Addressing reporting biases. In: Higgins JP, Green S, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from handbook.cochrane.org"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0196|cit196","doi-asserted-by":"crossref","first-page":"2693","DOI":"10.1002\/(SICI)1097-0258(19991030)18:20<2693::AID-SIM235>3.0.CO;2-V","article-title":"Explaining heterogeneity in meta-analysis: a comparison of methods","volume":"18","author":"Thompson","year":"1999","journal-title":"Statistics in Medicine"},{"key":"10.1002\/14651858.CD012234.pub2-BIB0197|cit197","unstructured":"World Health Organization (WHO) Global guidelines for the prevention of surgical site infection. November 2016 www.who.int\/gpsc\/ssi-prevention-guidelines\/en\/"},{"issue":"8476","key":"10.1002\/14651858.CD012234.pub2-BIB0198|cit198","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0140-6736(86)90838-X","article-title":"A scoring method (ASEPSIS) for postoperative wound infections for use in clinical trials of antibiotic prophylaxis","volume":"1","author":"Wilson","year":"1986","journal-title":"Lancet"},{"issue":"6","key":"10.1002\/14651858.CD012234.pub2-BIB0199|cit199","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012234","article-title":"Intracavity lavage and wound irrigation for prevention of surgical site infection","author":"Smith","year":"2016","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cochranelibrary.com\/cdsr\/doi\/10.1002\/14651858.CD012234.pub2\/epdf\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,27]],"date-time":"2023-08-27T19:15:45Z","timestamp":1693163745000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD012234.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Wounds Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,10,30]]},"references-count":199,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2017,10]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd012234.pub2","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,30]]}}}