{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T20:04:13Z","timestamp":1776888253418,"version":"3.51.2"},"update-to":[{"DOI":"10.1002\/14651858.cd013290","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T00:00:00Z","timestamp":1636416000000}}],"reference-count":125,"publisher":"Wiley","issue":"11","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd013290.pub2","type":"journal-article","created":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T23:53:26Z","timestamp":1636502006000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Perioperative systemic nonsteroidal anti-inflammatory drugs (NSAIDs) in women undergoing breast surgery"],"prefix":"10.1002","volume":"2021","author":[{"given":"Kevin M","family":"Klifto","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery; University of Missouri School of Medicine; Columbia USA"},{"name":"Department of Plastic and Reconstructive Surgery; Johns Hopkins University School of Medicine; Baltimore USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ala","family":"Elhelali","sequence":"additional","affiliation":[{"name":"School of Nursing and Midwifery; National University of Ireland Galway; Galway Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachael M","family":"Payne","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, Department of Surgery; Washington University School of Medicine; St Louis USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carisa M","family":"Cooney","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery; Johns Hopkins University School of Medicine; Baltimore USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele A","family":"Manahan","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery; Johns Hopkins University School of Medicine; Baltimore USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gedge D","family":"Rosson","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery; Johns Hopkins University School of Medicine; Baltimore USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,11,9]]},"reference":[{"issue":"10","key":"10.1002\/14651858.CD013290.pub2-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1097\/AJP.0000000000000338","article-title":"Comparison between the effects of intravenous morphine, tramadol, and ketorolac on stress and immune responses in patients undergoing modified radical mastectomy","volume":"32","author":"Bakr","year":"2016","journal-title":"Clinical Journal of Pain"},{"issue":"1","key":"10.1002\/14651858.CD013290.pub2-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/BF02409053","article-title":"Comparison of analgesic effect of locally and systemically administered ketorolac in mastectomy patients","volume":"3","author":"Bosek","year":"1996","journal-title":"Annals of Surgical Oncology"},{"issue":"6","key":"10.1002\/14651858.CD013290.pub2-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1111\/j.1365-2044.1996.tb12574.x","article-title":"Analgesia for day surgery: Evaluation of the effect of diclofenac given before or after surgery with or without bupivacaine infiltration","volume":"51","author":"Chan","year":"1996","journal-title":"Anaesthesia"},{"issue":"12","key":"10.1002\/14651858.CD013290.pub2-BIB0004|cit4","doi-asserted-by":"publisher","first-page":"e0225748","DOI":"10.1371\/journal.pone.0225748","article-title":"Intraoperative ketorolac in high-risk breast cancer patients. A prospective, randomized, placebo-controlled clinical trial","volume":"14","author":"Forget","year":"2019","journal-title":"PLoS One"},{"issue":"1","key":"10.1002\/14651858.CD013290.pub2-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.asj.2005.11.001","article-title":"Celecoxib reduces narcotic use and pain following augmentation mammaplasty","volume":"26","author":"Freedman","year":"2006","journal-title":"Aesthetic Surgery Journal"},{"issue":"9","key":"10.1002\/14651858.CD013290.pub2-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1111\/j.1399-6576.2005.00811.x","article-title":"Analgesic efficacy of diclofenac in combination with morphine and paracetamol after mastectomy and immediate breast reconstruction","volume":"49","author":"Legeby","year":"2005","journal-title":"Acta Anaesthesiologica Scandinavica"},{"issue":"6","key":"10.1002\/14651858.CD013290.pub2-BIB0007|cit7","first-page":"341","article-title":"Synergistic effect of intravenous ibuprofen and hydromorphone for postoperative pain: prospective randomized controlled trial","volume":"19","author":"Oh","year":"2016","journal-title":"Pain Physician"},{"issue":"6","key":"10.1002\/14651858.CD013290.pub2-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/s00266-005-0032-1","article-title":"The use of celecoxib for reduction of pain after subpectoral breast augmentation","volume":"29","author":"Parsa","year":"2005","journal-title":"Aesthetic Plastic Surgery"},{"issue":"2","key":"10.1002\/14651858.CD013290.pub2-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1213\/01.ane.0000194358.46119.e1","article-title":"Methylprednisolone reduces pain, emesis, and fatigue after breast augmentation surgery: a single-dose, randomized, parallel-group study with methylprednisolone 125 mg, parecoxib 40 mg, and placebo","volume":"102","author":"Romundstad","year":"2006","journal-title":"Anesthesia and Analgesia"},{"issue":"7","key":"10.1002\/14651858.CD013290.pub2-BIB0010|cit10","first-page":"653","article-title":"Effect of perioperative intravenous flurbiprofen axetil on chronic postmastectomy pain","volume":"38","author":"Sun","year":"2013","journal-title":"Journal of Central South University. Medical Sciences"},{"issue":"12","key":"10.1002\/14651858.CD013290.pub2-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"e0166601","DOI":"10.1371\/journal.pone.0166601","article-title":"Hyperalgesia and persistent pain after breast cancer surgery: a prospective randomized controlled trial with perioperative COX-2 inhibition","volume":"11","author":"Helmond","year":"2016","journal-title":"PloS One"},{"issue":"6","key":"10.1002\/14651858.CD013290.pub2-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1111\/papr.12206","article-title":"A comparison of fentanyl and flurbiprofen axetil on serum VEGF-C, TNF-\u03b1, and IL-1\u00df concentrations in women undergoing surgery for breast cancer","volume":"15","author":"Wen","year":"2015","journal-title":"Pain Practice"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0013|cit13","unstructured":"Pre-surgical aromatase inhibitor combined with non-steroidal anti inflammatory drug treatment in breast cancer anzctr.org.au\/Trial\/Registration\/TrialReview.aspx?id=366263 https:\/\/www.anzctr.org.au\/Trial\/Registration\/TrialReview.aspx?id=366263"},{"issue":"5","key":"10.1002\/14651858.CD013290.pub2-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"349-56","DOI":"10.1158\/1940-6207.CAPR-15-0311","article-title":"A randomized, placebo-controlled, phase II, presurgical biomarker trial of celecoxib versus exemestane in postmenopausal breast cancer patients","volume":"9","author":"Aristarco","year":"2016","journal-title":"Cancer Prevention Research"},{"issue":"4","key":"10.1002\/14651858.CD013290.pub2-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"443e","DOI":"10.1097\/PRS.0000000000004804","article-title":"Preoperative multimodal analgesia decreases postanesthesia care unit narcotic use and pain scores in outpatient breast surgery","volume":"142","author":"Barker","year":"2018","journal-title":"Plastic and Reconstructive Surgery"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0016|cit16","unstructured":"Betambeau N Davies G Sacks N Gui G MacNeill F Ebbs S Molecular effects of cyclooxygenase-2 (Cox-2) inhibition in primary breast cancer in vivo Breast Cancer Research and Treatment 2004 88 S240"},{"issue":"1","key":"10.1002\/14651858.CD013290.pub2-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/BF00209787","article-title":"NSAID as pre- and postoperative medication - A potential risk for bleeding complications in reduction mammaplasty","volume":"19","author":"Blomqvist","year":"1996","journal-title":"European Journal of Plastic Surgery"},{"issue":"6","key":"10.1002\/14651858.CD013290.pub2-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"480-3","DOI":"10.1016\/0952-8180(92)90223-N","article-title":"Ketorolac or fentanyl to supplement local anesthesia?","volume":"4","author":"Bosek","year":"1992","journal-title":"Journal of Clinical Anesthesia"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0019|cit19","first-page":"69","article-title":"Locally or systemically administered ketorolac improves quality of pain control after mastectomy","volume":"32","author":"Bosek","year":"1994","journal-title":"Breast Cancer Research and Treatment"},{"issue":"2","key":"10.1002\/14651858.CD013290.pub2-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/bcr3409","article-title":"A randomised controlled phase II trial of pre-operative celecoxib treatment reveals anti-tumour transcriptional response in primary breast cancer","volume":"15","author":"Brandao","year":"2013","journal-title":"Breast Cancer Research"},{"issue":"5","key":"10.1002\/14651858.CD013290.pub2-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"1605-12","DOI":"10.1158\/1078-0432.CCR-09-1623","article-title":"Cyclooxygenase-2 inhibition does not improve the reduction in ductal carcinoma in situ proliferation with aromatase inhibitor therapy: results of the ERISAC randomized placebo-controlled trial","volume":"16","author":"Bundred","year":"2010","journal-title":"Clinical Cancer Research"},{"issue":"5","key":"10.1002\/14651858.CD013290.pub2-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1007\/s12630-012-9682-z","article-title":"Retrospective analysis of perioperative ketorolac and postoperative bleeding in reduction mammoplasty","volume":"59","author":"Cawthorn","year":"2012","journal-title":"Canadian Journal of Anaesthesia"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0023|cit23","unstructured":"Research on approaches to improving cancer patients perioperative immunity and reducing postsurgical cancer recurrence chictr.org.cn\/showprojen.aspx?proj=9564"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0024|cit24","unstructured":"A study to note the effect of giving pregabalin before surgery on pain on patients going to have breast surgery ctri.nic.in\/Clinicaltrials\/pdf_generate.php?trialid=11107 http:\/\/ctri.nic.in\/Clinicaltrials\/pdf_generate.php?trialid=11107&EncHid=&modid=&compid=%27,%2711107det%27"},{"issue":"3","key":"10.1002\/14651858.CD013290.pub2-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/tbj.12950","article-title":"Single dose systemic acetaminophen to improve patient reported quality of recovery after ambulatory segmental mastectomy: A prospective, randomized, double-blinded, placebo controlled, clinical trial","volume":"24","author":"De Oliveira Jr","year":"2018","journal-title":"Breast Journal"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD013290.pub2-BIB0026|cit26","first-page":"4","article-title":"Differential benefit of intra-operative administration of ketorolac on breast cancer disease recurrence according to baseline body mass index","volume":"78","author":"Desmedt","year":"2017","journal-title":"Cancer Research"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0027|cit27","unstructured":"Ketorolac during breast cancer surgery clinicaltrialsregister.eu\/ctr-search\/search?query=2012-003774-76 https:\/\/www.clinicaltrialsregister.eu\/ctr-search\/search?query=eudract_number:2012-003774-76"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0028|cit28","first-page":"91","article-title":"Impact of extended perioperative cyclooxygenase (cox) - 2 inhibition on chronic pain after surgery for breast cancer","volume":"14","author":"Filippini-de Moor","year":"2014","journal-title":"Pain Practice"},{"issue":"6","key":"10.1002\/14651858.CD013290.pub2-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1213\/ANE.0b013e3181d2ad07","article-title":"Do intraoperative analgesics influence breast cancer recurrence after mastectomy? A retrospective analysis","volume":"110","author":"Forget","year":"2010","journal-title":"Anesthesia and Analgesia"},{"issue":"4","key":"10.1002\/14651858.CD013290.pub2-BIB0030|cit30","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.mehy.2013.07.033","article-title":"Perioperative ketorolac in high risk breast cancer patients. Rationale, feasibility and methodology of a prospective randomized placebo-controlled trial","volume":"81","author":"Forget","year":"2013","journal-title":"Medical Hypotheses"},{"issue":"Suppl 1","key":"10.1002\/14651858.CD013290.pub2-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1093\/bja\/aet464","article-title":"Intraoperative use of ketorolac or diclofenac is associated with improved disease-free survival and overall survival in conservative breast cancer surgery","volume":"113","author":"Forget","year":"2014","journal-title":"British Journal of Anaesthesia"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0032|cit32","first-page":"283","article-title":"The effect of diclofenac on platelet aggregation and post-operative bleeding","volume":"2","author":"Francis","year":"1988","journal-title":"Hematology Reviews"},{"issue":"1","key":"10.1002\/14651858.CD013290.pub2-BIB0033|cit33","first-page":"71","article-title":"Influence of ketoprofen on drainage volume after radical breast cancer surgery: a prospective randomized clinical trial","volume":"8","author":"Hidar","year":"2007","journal-title":"Turkish German Gynecological Association"},{"issue":"7","key":"10.1002\/14651858.CD013290.pub2-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"436-41","DOI":"10.1185\/03007998509109616","article-title":"Administration of ketoprofen suppositories for out-patient post-operative analgesia","volume":"9","author":"Himendra","year":"1985","journal-title":"Current Medical Research and Opinion"},{"issue":"39","key":"10.1002\/14651858.CD013290.pub2-BIB0035|cit35","first-page":"2751","article-title":"Effect of preemptive analgesia with flurbiprofen axetil on postoperative blood glucose and interleukin-6 levels in patients with breast cancer","volume":"89","author":"Hu","year":"2009","journal-title":"Chinese Medical Journal"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0036|cit36","unstructured":"Non-steroidal anti-inflammatory drug (NSAID) use in breast surgery: prospective randomised trial isrctn.com\/search?q=ISRCTN06628870 http:\/\/www.isrctn.com\/ISRCTN06628870?q=cancer%20-radiotherapy&filters=recruitmentCountry:Tunisia&sort=&offset=3&totalResults=3&page=1&pageSize=10&searchType=basic-search"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0037|cit37","unstructured":"Pre-surgical effects of serms, anti-COX-2 and aromatase inhibitors in breast cancer patients isrctn.com\/search?q=ISRCTN86894592"},{"issue":"10","key":"10.1002\/14651858.CD013290.pub2-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"1949-54","DOI":"10.1185\/030079906X132659","article-title":"Clinical equivalence of IV paracetamol compared to IV dipyrone for postoperative analgesia after surgery for breast cancer","volume":"22","author":"Kampe","year":"2006","journal-title":"Current Medical Research and Opinion"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"149-50","DOI":"10.1097\/00003643-201206001-00492","article-title":"Can preoperative flurbiprofen axetil reduce the total dose of fentanyl and sevoflurane for breast-conserving surgery?","volume":"29","author":"Kodaka","year":"2012","journal-title":"European Journal of Anaesthesiology"},{"issue":"4","key":"10.1002\/14651858.CD013290.pub2-BIB0040|cit40","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1097\/00000539-200104000-00048","article-title":"Ketorolac is not nephrotoxic in connection with sevoflurane anesthesia in patients undergoing breast surgery","volume":"92","author":"Laisalmi","year":"2001","journal-title":"Anesthesia and Analgesia"},{"issue":"5","key":"10.1002\/14651858.CD013290.pub2-BIB0041|cit41","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1097\/00000539-200111000-00033","article-title":"The effect of ketorolac and sevoflurane anesthesia on renal glomerular and tubular function","volume":"93","author":"Laisalmi","year":"2001","journal-title":"Anesthesia and Analgesia"},{"issue":"3","key":"10.1002\/14651858.CD013290.pub2-BIB0042|cit42","first-page":"259","article-title":"Preventive analgesic effect of intraoperative administration of ibuprofen-arginine on postmastectomy pain syndrome","volume":"84","author":"Lakdja","year":"1997","journal-title":"Bulletin du Cancer"},{"issue":"2","key":"10.1002\/14651858.CD013290.pub2-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1097\/01.prs.0000298112.52389.e1","article-title":"Locally administered ketorolac and bupivacaine for control of postoperative pain in breast augmentation patients: part II. 10-day follow-up","volume":"121","author":"Mahabir","year":"2008","journal-title":"Plastic and Reconstructive Surgery"},{"issue":"3","key":"10.1002\/14651858.CD013290.pub2-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1007\/s10549-010-1100-z","article-title":"Pre-surgical study of the biological effects of the selective cyclo-oxygenase-2 inhibitor celecoxib in patients with primary breast cancer","volume":"123","author":"Martin","year":"2010","journal-title":"Breast Cancer Research & Treatment"},{"issue":"Suppl 4","key":"10.1002\/14651858.CD013290.pub2-BIB0045|cit45","first-page":"4","article-title":"Pain management following breast cancer surgery: a double-blind randomized controlled study comparing acetaminophen plus ibuprofen to acetaminophen plus codeine plus caffeine","volume":"52","author":"McCrea","year":"2009","journal-title":"Canadian Journal of Surgery"},{"issue":"12","key":"10.1002\/14651858.CD013290.pub2-BIB0046|cit46","doi-asserted-by":"crossref","first-page":"3792","DOI":"10.1245\/s10434-012-2447-7","article-title":"A randomized, controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine (Tylenol 3) after outpatient breast surgery","volume":"19","author":"Mitchell","year":"2012","journal-title":"Annals of Surgical Oncology"},{"issue":"1","key":"10.1002\/14651858.CD013290.pub2-BIB0047|cit47","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1590\/S0100-69912009000100003","article-title":"Evaluation of the analgesic effects of the lumiracoxib compared with placebo in the 24 first postoperative hours","volume":"36","author":"Molon","year":"2009","journal-title":"Revista do colegio brasileiro de cirurgioes"},{"issue":"12","key":"10.1002\/14651858.CD013290.pub2-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1007\/BF03009600","article-title":"Ketorolac and indomethacin are equally efficacious for the relief of minor postoperative pain","volume":"40","author":"Morley-Forster","year":"1993","journal-title":"Canadian Journal of Anaesthesia"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0049|cit49","unstructured":"Celecoxib in treating postmenopausal women who are undergoing surgery for invasive breast cancer clinicaltrials.gov\/ct2\/show\/NCT00070057 https:\/\/ClinicalTrials.gov\/show\/NCT00070057"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0050|cit50","unstructured":"Efficacy and safety of parecoxib IV\/IM 40 mg vs placebo following sub muscular breast augmentation clinicaltrials.gov\/ct2\/show\/NCT00435747"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0051|cit51","unstructured":"Perioperative administration of COX 2 inhibitors and beta blockers to women undergoing breast cancer surgery clinicaltrials.gov\/ct2\/show\/NCT00502684 https:\/\/ClinicalTrials.gov\/show\/NCT00502684"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0052|cit52","unstructured":"Randomized controlled phase II trial of pre-operative celecoxib treatment in breast cancer clinicaltrials.gov\/ct2\/show\/NCT01695226 https:\/\/ClinicalTrials.gov\/show\/NCT01695226"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0053|cit53","unstructured":"Ketorolac in breast cancer surgery (KBCt) clinicaltrials.gov\/ct2\/show\/NCT01806259 https:\/\/ClinicalTrials.gov\/show\/NCT01806259"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0054|cit54","unstructured":"Perioperative systemic acetaminophen to improve postoperative quality of recovery after ambulatory breast surgery clinicaltrials.gov\/ct2\/show\/NCT01852955"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0055|cit55","unstructured":"A single dose of intravenous (IV) scetaminophen versus placebo in the pre-operative setting and outcomes on post-operative pain, nausea and vomiting clinicaltrials.gov\/ct2\/show\/NCT02102555"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0056|cit56","unstructured":"Perioperative inflammation and breast cancer outcome clinicaltrials.gov\/ct2\/show\/NCT02141139"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0057|cit57","unstructured":"Synergistic effect of ibuprofen and hydromorphone for postoperative pain clinicaltrials.gov\/ct2\/show\/NCT02461056"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0058|cit58","unstructured":"Ketorolac for Analgesia followiNG Autologous Breast RecOnstructiOn (KANGAROO) clinicaltrials.gov\/ct2\/show\/NCT03007381"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0059|cit59","unstructured":"Celecoxib window of opportunity trial to assess tumor and stroma responses clinicaltrials.gov\/ct2\/show\/NCT03185871 https:\/\/ClinicalTrials.gov\/show\/NCT03185871"},{"issue":"2","key":"10.1002\/14651858.CD013290.pub2-BIB0060|cit60","first-page":"185","article-title":"Toradol use in breast reconstruction: Risk of hematoma and benefit of post-operative pain control","volume":"25","author":"Nguyen","year":"2018","journal-title":"Annals of Surgical Oncology"},{"issue":"6","key":"10.1002\/14651858.CD013290.pub2-BIB0061|cit61","doi-asserted-by":"crossref","first-page":"814e","DOI":"10.1097\/PRS.0000000000004361","article-title":"Toradol following breast surgery: is there an increased risk of hematoma?","volume":"141","author":"Nguyen","year":"2018","journal-title":"Plastic and Reconstructive Surgery"},{"issue":"8","key":"10.1002\/14651858.CD013290.pub2-BIB0062|cit62","doi-asserted-by":"crossref","first-page":"648-53","DOI":"10.1097\/EJA.0b013e328329b0fd","article-title":"Paracetamol versus metamizol in the treatment of postoperative pain after breast surgery: a randomized, controlled trial","volume":"26","author":"Ohnesorge","year":"2009","journal-title":"European Journal of Anaesthesiology"},{"issue":"1","key":"10.1002\/14651858.CD013290.pub2-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1007\/s00266-008-9230-y","article-title":"Combined preoperative use of celecoxib and gabapentin in the management of postoperative pain","volume":"33","author":"Parsa","year":"2009","journal-title":"Aesthetic Plastic Surgery"},{"issue":"3","key":"10.1002\/14651858.CD013290.pub2-BIB0064|cit64","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1213\/00000539-200209000-00025","article-title":"Pain as a factor complicating recovery and discharge after ambulatory surgery","volume":"95","author":"Pavlin","year":"2002","journal-title":"Anesthesia and Analgesia"},{"issue":"2","key":"10.1002\/14651858.CD013290.pub2-BIB0065|cit65","first-page":"109-12","article-title":"Efficacy of intravenous ketoprofen for pre-emptive analgesia","volume":"48","author":"Priya","year":"2002","journal-title":"Journal of Postgraduate Medicine"},{"issue":"2","key":"10.1002\/14651858.CD013290.pub2-BIB0066|cit66","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1007\/s10549-012-2094-5","article-title":"NSAID analgesic ketorolac used perioperatively may suppress early breast cancer relapse: particular relevance to triple negative subgroup","volume":"134","author":"Retsky","year":"2012","journal-title":"Breast Cancer Research & Treatment"},{"issue":"33","key":"10.1002\/14651858.CD013290.pub2-BIB0067|cit67","doi-asserted-by":"crossref","first-page":"4163","DOI":"10.2174\/09298673113209990250","article-title":"Reduction of breast cancer relapses with perioperative non-steroidal anti-inflammatory drugs: New findings and a review","volume":"20","author":"Retsky","year":"2013","journal-title":"Current Medicinal Chemistry"},{"issue":"3","key":"10.1002\/14651858.CD013290.pub2-BIB0068|cit68","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1017\/S026502150500222X","article-title":"Does perioperative administration of rofecoxib improve analgesia after spine, breast and orthopaedic surgery?","volume":"23","author":"Riest","year":"2006","journal-title":"European Journal of Anaesthesiology"},{"issue":"1-2","key":"10.1002\/14651858.CD013290.pub2-BIB0069|cit69","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.pain.2006.03.020","article-title":"Chronic pain and sensory changes after augmentation mammoplasty: long term effects of preincisional administration of methylprednisolone","volume":"124","author":"Romundstad","year":"2006","journal-title":"Pain"},{"issue":"16","key":"10.1002\/14651858.CD013290.pub2-BIB0070|cit70","doi-asserted-by":"crossref","first-page":"4651","DOI":"10.1158\/1078-0432.CCR-17-0152","article-title":"Perioperative COX-2 and \u03b2-adrenergic blockade improves metastatic biomarkers in breast cancer patients in a phase-II randomized trial","volume":"23","author":"Shaashua","year":"2017","journal-title":"Clinical Cancer Research"},{"issue":"2","key":"10.1002\/14651858.CD013290.pub2-BIB0071|cit71","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1097\/00006534-200102000-00009","article-title":"Incidence of hematoma associated with ketorolac after TRAM flap breast reconstruction","volume":"107","author":"Sharma","year":"2001","journal-title":"Plastic and Reconstructive Surgery"},{"issue":"3","key":"10.1002\/14651858.CD013290.pub2-BIB0072|cit72","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1213\/ane.0b013e3181618831","article-title":"Perioperative versus postoperative celecoxib on patient outcomes after major plastic surgery procedures","volume":"106","author":"Sun","year":"2008","journal-title":"Anesthesia and Analgesia"},{"issue":"10","key":"10.1002\/14651858.CD013290.pub2-BIB0073|cit73","first-page":"e251","article-title":"Impact of the perioperative use of intravenous acetaminophen in patients undergoing intraabdominal and breast reconstruction surgery","volume":"34","author":"Tallian","year":"2014","journal-title":"Pharmacotherapy"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0074|cit74","first-page":"96","article-title":"Impact of extended perioperative cyclooxygenase (COX)-2 inhibition on quality of life after surgery for breast cancer","volume":"14","author":"Helmond","year":"2014","journal-title":"Pain Practice"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0075|cit75","unstructured":"The effect of intra-operative ketorolac on hematoma rates in breast reduction surgery clinicaltrials.gov\/ct2\/show\/NCT03535116"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0076|cit76","volume-title":"Breast Cancer Facts & Figures 2017-2018","author":"American Cancer Society","year":"2017"},{"issue":"5","key":"10.1002\/14651858.CD013290.pub2-BIB0077|cit77","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1056\/NEJMc060373","article-title":"COX-2 inhibitors and early failure of free vascular flaps","volume":"355","author":"Al-Sukhun","year":"2006","journal-title":"New England Journal of Medicine"},{"issue":"2","key":"10.1002\/14651858.CD013290.pub2-BIB0078|cit78","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1097\/ALN.0b013e31823c1030","article-title":"Practice guidelines for acute pain management in the perioperative setting: an updated report by the American Society of Anesthesiologists Task Force on Acute Pain Management","volume":"116","author":"American Society of Anesthesiologists","year":"2012","journal-title":"Anesthesiology"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0079|cit79","unstructured":"American Society of Plastic Surgeons 2017 Plastic Surgery Statistics Report www.plasticsurgery.org\/documents\/News\/Statistics\/2017\/plastic-surgery-statistics-report-2017.pdf 2017"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0080|cit80","unstructured":"American Society of Plastic Surgeons How should I prepare for breast reduction surgery? www.plasticsurgery.org\/reconstructive-procedures\/breast-reduction\/preparation 2018"},{"issue":"3","key":"10.1002\/14651858.CD013290.pub2-BIB0081|cit81","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.bjps.2014.11.014","article-title":"Enhanced recovery after surgery in microvascular breast reconstruction","volume":"68","author":"Batdorf","year":"2015","journal-title":"Journal of Plastic, Reconstructive & Aesthetic Surgery"},{"issue":"6","key":"10.1002\/14651858.CD013290.pub2-BIB0082|cit82","doi-asserted-by":"crossref","first-page":"367","DOI":"10.3109\/2000656X.2015.1062387","article-title":"Introducing the fast track surgery principles can reduce length of stay after autologous breast reconstruction using free flaps: A case control study","volume":"49","author":"Bonde","year":"2015","journal-title":"Journal of Plastic Surgery and Hand Surgery"},{"issue":"2","key":"10.1002\/14651858.CD013290.pub2-BIB0083|cit83","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1097\/01.prs.0000475749.40838.85","article-title":"Perioperative optimization of autologous breast reconstruction","volume":"137","author":"Bonde","year":"2016","journal-title":"Plastic and Reconstructive Surgery"},{"issue":"11","key":"10.1002\/14651858.CD013290.pub2-BIB0084|cit84","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1016\/j.bjps.2017.06.007","article-title":"Cyclooxygenase-2 inhibitors and free flap complications after autologous breast reconstruction: a retrospective cohort study","volume":"70","author":"Bonde","year":"2017","journal-title":"Journal of Plastic, Reconstructive & Aesthetic Surgery"},{"issue":"12","key":"10.1002\/14651858.CD013290.pub2-BIB0085|cit85","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012033.pub4","article-title":"Perioperative intravenous ketamine for acute postoperative pain in adults","author":"Brinck","year":"2018","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0086|cit86","volume-title":"Goodman & Gilman's The pharmacological Basis of Therapeutics","author":"Brunton","year":"2017"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0087|cit87","doi-asserted-by":"crossref","unstructured":"Cheng NX Chen B Li Q Wu DH Zhu L Zhang XM Late haematoma and seroma in patients with silicone mammary prosthesis: our reports and literature review Journal of Plastic, Reconstructive & Aesthetic Surgery 2011 64 7 e185 6 21474400","DOI":"10.1016\/j.bjps.2011.03.004"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0088|cit88","first-page":"1344","article-title":"An evidence-based review of the efficacy of perioperative analgesic techniques for breast cancer-related surgery","volume":"18","author":"Cheng","year":"2017","journal-title":"Pain Medicine"},{"issue":"2","key":"10.1002\/14651858.CD013290.pub2-BIB0089|cit89","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.jpain.2015.12.008","article-title":"Management of postoperative pain: a Clinical Practice Guideline from the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists' Committee on Regional Anesthesia, Executive Committee, and Administrative Council","volume":"17","author":"Chou","year":"2016","journal-title":"Journal of Pain"},{"issue":"3","key":"10.1002\/14651858.CD013290.pub2-BIB0090|cit90","doi-asserted-by":"crossref","first-page":"413e","DOI":"10.1097\/PRS.0b013e3182402ce0","article-title":"Incidence of breast hematoma after placement of breast prostheses","volume":"129","author":"Collins","year":"2012","journal-title":"Plastic and Reconstructive Surgery"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0091|cit91","unstructured":"Covidence Veritas Health Innovation"},{"issue":"3","key":"10.1002\/14651858.CD013290.pub2-BIB0092|cit92","doi-asserted-by":"crossref","first-page":"339e","DOI":"10.1097\/PRS.0b013e31829ace62","article-title":"Processes of care in autogenous breast reconstruction with pedicled TRAM flaps: expediting postoperative discharge in an ambulatory setting","volume":"132","author":"Davidge","year":"2013","journal-title":"Plastic and Reconstructive Surgery"},{"issue":"10","key":"10.1002\/14651858.CD013290.pub2-BIB0093|cit93","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1093\/jnci\/djy042","article-title":"Potential benefit of intra-operative administration of ketorolac on breast cancer recurrence according to the patient's body mass index","volume":"110","author":"Desmedt","year":"2018","journal-title":"Journal of the National Cancer Institute"},{"issue":"1","key":"10.1002\/14651858.CD013290.pub2-BIB0094|cit94","doi-asserted-by":"crossref","first-page":"18","DOI":"10.6004\/jnccn.2012.0005","article-title":"Value-based insurance design: aligning incentives, benefits, and evidence in oncology","volume":"10","author":"De Souza","year":"2012","journal-title":"Journal of the National Comprehensive Cancer Network"},{"issue":"3","key":"10.1002\/14651858.CD013290.pub2-BIB0095|cit95","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1097\/01.prs.0000438459.60474.b5","article-title":"Ketorolac does not increase perioperative bleeding: a meta-analysis of randomized controlled trials","volume":"133","author":"Gobble","year":"2014","journal-title":"Plastic and Reconstructive Surgery"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0096|cit96","unstructured":"GRADEpro GDT McMaster University (developed by Evidence Prime)"},{"issue":"5","key":"10.1002\/14651858.CD013290.pub2-BIB0097|cit97","doi-asserted-by":"crossref","first-page":"821","DOI":"10.18433\/J3VW2F","article-title":"Adverse effects of nonsteroidal antiinflammatory drugs: an update of gastrointestinal, cardiovascular and renal complications","volume":"16","author":"Harirforoosh","year":"2013","journal-title":"Journal of Pharmacy & Pharmaceutical Sciences"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0098|cit98","volume-title":"Facing Addiction in America: The Surgeon General's Report on Alcohol, Drugs, and Health","author":"US Department of Health and Human Services (HHS)","year":"2016"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0099|cit99","unstructured":"Higgins JP Green S Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011 Available from training.cochrane.org\/handbook\/archive\/v5.1\/"},{"issue":"6","key":"10.1002\/14651858.CD013290.pub2-BIB0100|cit100","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.jpainsymman.2010.08.016","article-title":"Studies comparing Numerical Rating Scales, Verbal Rating Scales, and Visual Analogue Scales for assessment of pain intensity in adults: a systematic literature review","volume":"41","author":"Hjermstad","year":"2011","journal-title":"Journal of Pain and Symptom Management"},{"issue":"9","key":"10.1002\/14651858.CD013290.pub2-BIB0101|cit101","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1056\/NEJM199403033300926","article-title":"New clinical-practice guidelines for the management of pain in patients with cancer","volume":"330","author":"Jacox","year":"1994","journal-title":"New England Journal of Medicine"},{"issue":"7","key":"10.1002\/14651858.CD013290.pub2-BIB0102|cit102","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1007\/s00535-012-0717-6","article-title":"Comparison of gastrointestinal adverse effects between cyclooxygenase-2 inhibitors and non-selective, non-steroidal anti-inflammatory drugs plus proton pump inhibitors: a systematic review and meta-analysis","volume":"48","author":"Jarupongprapa","year":"2013","journal-title":"Journal of Gastroenterology"},{"issue":"10","key":"10.1002\/14651858.CD013290.pub2-BIB0103|cit103","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1093\/asj\/sjx062","article-title":"Incidence and risk factors for major hematomas in aesthetic surgery: analysis of 129,007 patients","volume":"37","author":"Kaoutzanis","year":"2017","journal-title":"Aesthetic Surgery Journal"},{"issue":"5","key":"10.1002\/14651858.CD013290.pub2-BIB0104|cit104","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1093\/bja\/78.5.606","article-title":"Multimodal approach to control postoperative pathophysiology and rehabilitation","volume":"78","author":"Kehlet","year":"1997","journal-title":"British Journal of Anaesthesia"},{"issue":"7","key":"10.1002\/14651858.CD013290.pub2-BIB0105|cit105","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003591.pub3","article-title":"Nonsteroidal anti-inflammatory drugs and perioperative bleeding in paediatric tonsillectomy","author":"Lewis","year":"2013","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"5","key":"10.1002\/14651858.CD013290.pub2-BIB0106|cit106","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1097\/00000637-199705000-00007","article-title":"A controlled, randomized, double-blind study of ketorolac for postoperative analgesia after plastic surgery","volume":"38","author":"Mar\u00edn-Bertol\u00edn","year":"1997","journal-title":"Annals of Plastic Surgery"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0107|cit107","unstructured":"Perioperative - Merriam-Webster.com Dictionary www.merriam-webster.com\/dictionary\/perioperative https:\/\/www.merriam-webster.com\/dictionary\/perioperative"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0108|cit108","unstructured":"Pharmacogenomics - Merriam-Webster.com Dictionary www.merriam-webster.com\/dictionary\/pharmacogenomics"},{"issue":"5","key":"10.1002\/14651858.CD013290.pub2-BIB0109|cit109","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1097\/SAP.0000000000001409","article-title":"Ketorolac and hematoma incidence in postmastectomy implant-based breast reconstruction","volume":"80","author":"Mikhaylov","year":"2018","journal-title":"Annals of Plastic Surgery"},{"issue":"3","key":"10.1002\/14651858.CD013290.pub2-BIB0110|cit110","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1093\/bja\/aer505","article-title":"Simplified postoperative nausea and vomiting impact scale for audit and post-discharge review","volume":"108","author":"Myles","year":"2012","journal-title":"British Journal of Anaesthesia"},{"issue":"7","key":"10.1002\/14651858.CD013290.pub2-BIB0111|cit111","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1002\/ejp.842","article-title":"Preoperative preemptive drug administration for acute postoperative pain: a systematic review and meta-analysis","volume":"20","author":"Nir","year":"2016","journal-title":"European Journal of Pain"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0112|cit112","unstructured":"Review Manager (RevMan) Nordic Cochrane Centre, The Cochrane Collaboration 2020"},{"issue":"13","key":"10.1002\/14651858.CD013290.pub2-BIB0113|cit113","doi-asserted-by":"crossref","first-page":"1015\u201323","DOI":"10.1093\/eurheartj\/ehv505","article-title":"Cardiovascular safety of non-aspirin non-steroidal anti-inflammatory drugs: review and position paper by the working group for Cardiovascular Pharmacotherapy of the European Society of Cardiology","volume":"37","author":"Schmidt","year":"2016","journal-title":"European Heart Journal"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0114|cit114","unstructured":"Sch\u00fcnemann HJ Oxman AD Vist GE Higgins JP Deeks JJ Glaziou P Chapter 12: Interpreting results and drawing conclusions. In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, et al, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 6.2 (updated February 2021). Cochrane, 2021 Available from training.cochrane.org\/handbook"},{"issue":"1","key":"10.1002\/14651858.CD013290.pub2-BIB0115|cit115","doi-asserted-by":"crossref","first-page":"djw178","DOI":"10.1093\/jnci\/djw178","article-title":"Cost and complications of local therapies for early-stage breast cancer","volume":"109","author":"Smith","year":"2017","journal-title":"Journal of the National Cancer Institute"},{"issue":"4","key":"10.1002\/14651858.CD013290.pub2-BIB0116|cit116","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1093\/asj\/sjv005","article-title":"Is ketorolac safe to use in plastic surgery? A critical review","volume":"35","author":"Stephens","year":"2015","journal-title":"Aesthetic Surgery Journal"},{"key":"10.1002\/14651858.CD013290.pub2-BIB0117|cit117","doi-asserted-by":"crossref","first-page":"i4919","DOI":"10.1136\/bmj.i4919","article-title":"ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"Sterne","year":"2016","journal-title":"BMJ"},{"issue":"1","key":"10.1002\/14651858.CD013290.pub2-BIB0118|cit118","doi-asserted-by":"crossref","first-page":"e1855","DOI":"10.1097\/GOX.0000000000001855","article-title":"Implementing our microsurgical breast reconstruction enhanced recovery after surgery pathway: vonsensus obstacles and recommendations","volume":"7","author":"Stone","year":"2019","journal-title":"Plastic and Reconstructive Surgery. Global Open"},{"issue":"7","key":"10.1002\/14651858.CD013290.pub2-BIB0119|cit119","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1002\/alr.22107","article-title":"Perioperative analgesia for patients undergoing endoscopic sinus surgery: an evidence-based review","volume":"8","author":"Svider","year":"2018","journal-title":"International Forum of Allergy & Rhinology"},{"issue":"6S Suppl 5","key":"10.1002\/14651858.CD013290.pub2-BIB0120|cit120","doi-asserted-by":"crossref","first-page":"S437","DOI":"10.1097\/SAP.0000000000001898","article-title":"Hematoma risks of nonsteroidal anti-inflammatory drugs used in plastic surgery procedures: a systematic review and meta-analysis","volume":"82","author":"Walker","year":"2019","journal-title":"Annals of Plastic Surgery"},{"issue":"2","key":"10.1002\/14651858.CD013290.pub2-BIB0121|cit121","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1093\/bja\/aep370","article-title":"Development and validation of a postoperative nausea and vomiting intensity scale","volume":"104","author":"Wengritzky","year":"2010","journal-title":"British Journal of Anaesthesia"},{"issue":"1","key":"10.1002\/14651858.CD013290.pub2-BIB0122|cit122","doi-asserted-by":"crossref","first-page":"143","DOI":"10.14336\/AD.2017.0306","article-title":"A comprehensive review of non-steroidal anti-Inflammatory drug use in the elderly","volume":"9","author":"Wongrakpanich","year":"2018","journal-title":"Aging and Disease"},{"issue":"3","key":"10.1002\/14651858.CD013290.pub2-BIB0123|cit123","doi-asserted-by":"crossref","first-page":"166","DOI":"10.3109\/2000656X.2014.970639","article-title":"The cost of major complications associated with immediate two-stage expander\/implant-based breast reconstruction","volume":"49","author":"Yan","year":"2015","journal-title":"Journal of Plastic Surgery and Hand Surgery"},{"issue":"1","key":"10.1002\/14651858.CD013290.pub2-BIB0124|cit124","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s11916-009-0009-x","article-title":"Pain outcomes: a brief review of instruments and techniques","volume":"13","author":"Younger","year":"2009","journal-title":"Current Pain and Headache Reports"},{"issue":"3","key":"10.1002\/14651858.CD013290.pub2-BIB0125|cit125","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD013290","article-title":"Perioperative systemic nonsteroidal anti-inflammatory drugs (NSAIDs) in women undergoing breast surgery","author":"Klifto","year":"2019","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","deposited":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T10:33:41Z","timestamp":1721212421000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD013290.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Breast Cancer Group","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,11,9]]},"references-count":125,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2021,11]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd013290.pub2","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,9]]}}}