{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:19:46Z","timestamp":1790396386704,"version":"4.1.0"},"update-to":[{"DOI":"10.1002\/14651858.cd013381","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2021,9,8]],"date-time":"2021-09-08T00:00:00Z","timestamp":1631059200000}}],"reference-count":180,"publisher":"Wiley","issue":"9","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd013381.pub2","type":"journal-article","created":{"date-parts":[[2021,9,8]],"date-time":"2021-09-08T18:57:19Z","timestamp":1631127439000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Interventions to improve adherence to pharmacological therapy for chronic obstructive pulmonary disease (COPD)"],"prefix":"10.1002","volume":"2021","author":[{"given":"Sadia","family":"Janjua","sequence":"additional","affiliation":[{"name":"Cochrane Airways, Population Health Research Institute; St George's, University of London; London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharine C","family":"Pike","sequence":"additional","affiliation":[{"name":"Bristol Royal Hospital for Children; Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Carr","sequence":"additional","affiliation":[{"name":"28 Beaumont Street Medical Practice; Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andy","family":"Coles","sequence":"additional","affiliation":[{"name":"COPD Patient Advisory Group; St George's, University of London; London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Fortescue","sequence":"additional","affiliation":[{"name":"Cochrane Airways, Population Health Research Institute; St George's, University of London; London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell","family":"Batavia","sequence":"additional","affiliation":[{"name":"Steinhardt School of Culture, Education and Human Development, Department of Physical Therapy; New York University; New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,9,8]]},"reference":[{"key":"10.1002\/14651858.CD013381.pub2-BIB0001|cit1","first-page":"PA1988","article-title":"A randomized clinical study to assess the impact of budesonide\/formoterol (BUD\/FM) pMDI medication reminders on adherence in COPD patients","volume":"52","author":"Criner","year":"2018","journal-title":"European Respiratory Journal"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0002|cit2","unstructured":"Adherence study in COPD patients clinicaltrials.gov\/ct2\/show\/NCT02864342"},{"issue":"1","key":"10.1002\/14651858.CD013381.pub2-BIB0003|cit3","first-page":"19","article-title":"Compliance measure development and assessment of theophylline therapy in ambulatory patients","volume":"12","author":"De Tullio","year":"1987","journal-title":"Journal of Clinical Pharmacy and Therapeutics"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.pec.2019.12.004","article-title":"Shared decision-making and patient engagement program during acute exacerbation of COPD hospitalization: a randomized control trial","volume":"103","author":"Grandos-Santiago","year":"2020","journal-title":"Patient Education and Counselling"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0005|cit5","first-page":"PA3836","article-title":"Efficacy of a comprehensive education program including inhaler training and COPD management during hospitalization of AECOPD, a randomized controlled clinical","volume":"52","author":"Sanchez","year":"2018","journal-title":"European Respiratory Journal"},{"issue":"4","key":"10.1002\/14651858.CD013381.pub2-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.rmed.2012.12.020","article-title":"Influence of salmeterol\/fluticasone via single versus separate inhalers on exacerbations in severe\/very severe COPD","volume":"107","author":"Hagedorn","year":"2013","journal-title":"Respiratory Medicine"},{"issue":"1","key":"10.1002\/14651858.CD013381.pub2-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s11096-011-9585-z","article-title":"Impact of pharmaceutical care on health outcomes in patients with COPD","volume":"34","author":"Jarab","year":"2012","journal-title":"International Journal of Clinical Pharmacy"},{"issue":"4","key":"10.1002\/14651858.CD013381.pub2-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1111\/j.1365-2125.2009.03493.x","article-title":"Clinical pharmacy-led disease and medicine management programme for patients with COPD","volume":"68","author":"Khdour","year":"2009","journal-title":"British Journal of Clinical Pharmacology"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0009|cit9","doi-asserted-by":"crossref","unstructured":"Barnestein-Fonseca P Leiva-Fernandez J Vidal-Espana F Garcia-Ruiz A Prados-Torres D Leiva-Fernandez F Efficacy and safety of a multifactor intervention to improve therapeutic adherence in patients with chronic obstructive pulmonary disease (COPD): protocol for the ICEPOC study Trials 2011 12 40 1 9","DOI":"10.1186\/1745-6215-12-40"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0010|cit10","unstructured":"Educational intervention to improve the treatment adherence in patients with chronic obstructive pulmonary disease (COPD) ictrptest.azurewebsites.net\/Trial2.aspx?TrialID=ISRCTN18841601"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"A587","DOI":"10.1016\/j.jval.2011.08.1391","article-title":"Effectiveness of a multifactorial intervention to improve adherence in patients with chronic obstructive pulmonary disease (COPD). ICEPOC study","volume":"14","author":"Leiva-Fernandez","year":"2011","journal-title":"Value in Health"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"A373","DOI":"10.1016\/j.jval.2013.08.295","article-title":"Factors related to adherence after a multifactorial intervention to improve it in patients with chronic obstructive pulmonary disease (COPD). ICEPOC study","volume":"16","author":"Leiva-Fernandez","year":"2013","journal-title":"Value in Health"},{"issue":"70","key":"10.1002\/14651858.CD013381.pub2-BIB0013|cit13","first-page":"1","article-title":"Efficacy of a multifactorial intervention on therapeutic adherence in patients with chronic obstructive pulmonary disease (COPD): a randomized controlled trial","volume":"14","author":"Leiva-Fernandez","year":"2014","journal-title":"BMC Pulmonary Medicine"},{"issue":"21","key":"10.1002\/14651858.CD013381.pub2-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.2146\/ajhp120241","article-title":"A telepharmacy intervention to improve inhaler adherence in veterans with chronic obstructive pulmonary disease","volume":"70","author":"Margolis","year":"2013","journal-title":"American Journal of Health-System Pharmacy"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0015|cit15","unstructured":"A pilot study to evaluate a telepharmacy intervention to improve inhaler adherence in veterans with COPD clinicaltrials.gov\/show\/nct01270594"},{"issue":"2","key":"10.1002\/14651858.CD013381.pub2-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1111\/j.1447-0594.2012.00916.x","article-title":"Better adherence to a transdermal tulobuterol patch than inhaled salmeterol in elderly chronic obstructive pulmonary disease patients","volume":"13","author":"Mochizuki","year":"2013","journal-title":"Geriatrics and Gerontology International"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0017|cit17","unstructured":"Comparison of adherence and efficacy between inhaled salmeterol and transdermal tulobuterol patch in elderly COPD patients trialsearch.who.int\/Trial2.aspx?TrialID=JPRN-UMIN000001503"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0018|cit18","unstructured":"The effect of motivational interviewing (MI) on adherence to therapy in COPD patients ictrptest.azurewebsites.net\/Trial2.aspx?TrialID=IRCT201604128650N7"},{"issue":"4","key":"10.1002\/14651858.CD013381.pub2-BIB0019|cit19","first-page":"241","article-title":"Effects of motivational interviewing on treatment adherence among patients with chronic obstructive pulmonary disease: a randomized controlled clinical trial","volume":"17","author":"Naderloo","year":"2018","journal-title":"Tanaffus"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0020|cit20","unstructured":"A 24-week randomized, single blinded study in subjects with chronic obstructive pulmonary disease (COPD) to evaluate the effect of reminders and motivational\/adaptive messages on treatment adherence tracked by the Concept 2 inhaler ictrptest.azurewebsites.net\/Trial2.aspx?TrialID=EUCTR2017-001593-42-BE"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0021|cit21","unstructured":"A randomized study to evaluate the effect of reminder notifications and motivational\/adaptive messaging on treatment adherence (ADVICE) clinicaltrials.gov\/show\/nct03379233"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"871","DOI":"10.2147\/COPD.S191033","article-title":"Adherence to roflumilast under dose-escalation strategy in Korean patients with COPD","volume":"14","author":"Park","year":"2019","journal-title":"International Journal of Chronic Obstructive Pulmonary Disease"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0023|cit23","unstructured":"Aides in respiration health coaching for COPD (AIR) https:\/\/clinicaltrials.gov\/ct2\/show\/results\/NCT02234284 2014"},{"issue":"10","key":"10.1002\/14651858.CD013381.pub2-BIB0024|cit24","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1513\/AnnalsATS.201806-365OC","article-title":"Randomised controlled trial of health coaching for vulnerable patients with chronic obstructive pulmonary disease","volume":"15","author":"Thom","year":"2018","journal-title":"Annals of the American Thoracic Society"},{"issue":"1","key":"10.1002\/14651858.CD013381.pub2-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1370\/afm.2461","article-title":"Lay health coaching to increase appropriate inhaler use in COPD: a randomized controlled trial","volume":"18","author":"Willard-Grace","year":"2020","journal-title":"Annals of Family Medicine"},{"issue":"2","key":"10.1002\/14651858.CD013381.pub2-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"e12799","DOI":"10.1111\/ijn.12799","article-title":"An information-motivation-behavioural-based model and adherence to inhalation therapy and other health outcomes in patients with chronic obstructive pulmonary disease: a pilot randomized controlled trial","volume":"26","author":"To","year":"2020","journal-title":"International Journal of Nursing Practice"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0027|cit27","unstructured":"To KW The effects of an education-based adherence intervention on adherence of inhalation therapy among patients with chronic obstructive pulmonary disease Unpublished doctoral thesis 2017 37 113"},{"issue":"5","key":"10.1002\/14651858.CD013381.pub2-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1111\/bcp.12242","article-title":"Effectiveness of pharmaceutical care for patients with chronic obstructive pulmonary disease (PHARMACOP): a randomized controlled trial","volume":"77","author":"Tommelein","year":"2014","journal-title":"British Journal of Clinical Pharmacology"},{"issue":"1","key":"10.1002\/14651858.CD013381.pub2-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/1465-9921-15-66","article-title":"Improving inhaler adherence in patients with chronic obstructive pulmonary disease: a cost-effectiveness analysis","volume":"15","author":"Van Boven","year":"2014","journal-title":"Respiratory Research"},{"issue":"6","key":"10.1002\/14651858.CD013381.pub2-BIB0030|cit30","first-page":"656","article-title":"Effect of pharmaceutical care on medication adherence and hospital admission in patients with chronic obstructive pulmonary disease (COPD): a randomized controlled study","volume":"6","author":"Wei","year":"2014","journal-title":"Journal of Thoracic Disease"},{"issue":"11","key":"10.1002\/14651858.CD013381.pub2-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.jagp.2016.07.014","article-title":"Two behavioural interventions for patients with major depression and severe COPD","volume":"24","author":"Alexopoulos","year":"2016","journal-title":"American Journal of Geriatric Psychiatry"},{"issue":"47","key":"10.1002\/14651858.CD013381.pub2-BIB0032|cit32","first-page":"55","article-title":"Innovative inhalation system can improve compliance. Long-term therapy becomes simpler","volume":"149","year":"2007","journal-title":"MMW Fortschritte der Medizin"},{"issue":"2","key":"10.1002\/14651858.CD013381.pub2-BIB0033|cit33","first-page":"306","article-title":"Efficacy of indacaterol, a modern ultralong-acting bronchodilator, in elderly patients with chronic obstructive pulmonary disease","volume":"63","author":"Berbecaru-Iovan","year":"2015","journal-title":"Farmacia"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0034|cit34","first-page":"A2952","article-title":"Phase II multi-centre trial with inhaled bimosiamose in ambulatory patients with moderate to severe COPD: evaluation of dose compliance","volume":"185","author":"Bock","year":"2012","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0035|cit35","first-page":"PA3961","article-title":"COPD medication adherence and quality of life","volume":"48","author":"Boland","year":"2016","journal-title":"European Respiratory Journal"},{"issue":"Suppl 45","key":"10.1002\/14651858.CD013381.pub2-BIB0036|cit36","first-page":"1609","article-title":"The improvement in quality of life in patients with COPD: the influence of long term regular monitoring and good compliance","volume":"22","author":"Botvinikova","year":"2003","journal-title":"European Respiratory Journal"},{"issue":"4","key":"10.1002\/14651858.CD013381.pub2-BIB0037|cit37","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1440-1843.1997.tb00094.x","article-title":"The US Lung Health Study","volume":"2","author":"Buist","year":"1997","journal-title":"Respirology"},{"issue":"2","key":"10.1002\/14651858.CD013381.pub2-BIB0038|cit38","first-page":"99","article-title":"A comparative study of patients' preferences and sensory perceptions of three forms of inhalers among Thai asthma and COPD patients","volume":"25","author":"Bunnag","year":"2007","journal-title":"Asian Pacific Journal of Allergy and Immunology"},{"issue":"13","key":"10.1002\/14651858.CD013381.pub2-BIB0039|cit39","first-page":"586","article-title":"Effectiveness of the correct use of inhalation devices in patients with COPD: randomized clinical trial","volume":"135","author":"Cabedo Garcia","year":"2010","journal-title":"Medicina Clinica"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0040|cit40","first-page":"P928","article-title":"Preference, satisfaction and critical errors with Genuair\u00ae and Breezhaler\u00ae in patients with COPD","volume":"44","author":"Chrystyn","year":"2014","journal-title":"European Respiratory Journal"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0041|cit41","first-page":"A229","article-title":"Describing adherence data in a clinical effectiveness trial: the Salford lung study in COPD (SLS COPD)","volume":"72","author":"Collier","year":"2017","journal-title":"Thorax"},{"issue":"10","key":"10.1002\/14651858.CD013381.pub2-BIB0042|cit42","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/S0954-6111(03)00162-8","article-title":"Assessment of patient performance of the HandiHaler compared with the metered dose inhaler four weeks after instruction","volume":"97","author":"Dahl","year":"2003","journal-title":"Respiratory Medicine"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0043|cit43","unstructured":"Study to evaluate how to optimise the use of Roflumilast in subjects who have a lung disease called chronic obstructive pulmonary disease (COPD) ictrptest.azurewebsites.net\/Trial2.aspx?TrialID=EUCTR2013-001788-21-GB"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.cct.2019.06.018","article-title":"Prediction using a randomized evaluation of data collection integrated through connected technologies (PREDICT): design and rationale of a randomized trial of patients discharged from the hospital to home","volume":"83","author":"Evans","year":"2019","journal-title":"Contemporary Clinical Trials"},{"issue":"2","key":"10.1002\/14651858.CD013381.pub2-BIB0045|cit45","first-page":"174","article-title":"Pharmaceutical care for patients with chronic conditions","volume":"40","author":"Fischer","year":"2000","journal-title":"Journal of the American Pharmaceutical Association"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0046|cit46","first-page":"A275","article-title":"Effect of patient education on compliance in asthmatics and chronic obstructive lung disease","volume":"157","author":"Gallefoss","year":"1998","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"issue":"6","key":"10.1002\/14651858.CD013381.pub2-BIB0047|cit47","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1164\/ajrccm.160.6.9901028","article-title":"How does patient education and self-management among asthmatics and patients with chronic obstructive pulmonary disease affect medication?","volume":"160","author":"Gallefoss","year":"1999","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"issue":"7","key":"10.1002\/14651858.CD013381.pub2-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1016\/j.rmed.2007.01.012","article-title":"Effects of an integrated care intervention on risk factors of COPD readmission","volume":"101","author":"Garcia-Aymerich","year":"2007","journal-title":"Respiratory Medicine"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0049|cit49","first-page":"207s","article-title":"Impact of a home care program on adherence to treatment in patients with COPD","volume":"18","author":"Hernandez","year":"2001","journal-title":"European Respiratory Journal"},{"issue":"7","key":"10.1002\/14651858.CD013381.pub2-BIB0050|cit50","first-page":"535","article-title":"Compliance improving measures in the treatment of obstructive lung diseases","volume":"42","author":"Holzer","year":"1988","journal-title":"Praxis und Klinik der Pneumologie"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0051|cit51","first-page":"A3037","article-title":"A randomized controlled trial comparing two dry powder inhalers: more patients with COPD prefer ellipta compared to diskus based on device-specific attributes","volume":"189","author":"Kirby","year":"2014","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"issue":"6","key":"10.1002\/14651858.CD013381.pub2-BIB0052|cit52","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1001\/archinte.167.6.540","article-title":"Interventions to enhance medication adherence in chronic medical conditions: a systematic review","volume":"167","author":"Kripalani","year":"2007","journal-title":"Archives of Internal Medicine"},{"issue":"11","key":"10.1002\/14651858.CD013381.pub2-BIB0053|cit53","first-page":"225","article-title":"A new inhalation system for bronchodilatation. Study of the acceptance of the Ingelheim M inhaler in chronic obstructive respiratory tract diseases","volume":"108","author":"Mutterlein","year":"1990","journal-title":"Fortschritte der Medizin"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0054|cit54","unstructured":"Medication adherence in COPD - a self-regulation study clinicaltrials.gov\/show\/nct00005717"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0055|cit55","unstructured":"A crossover study in the treatment of patients with COPD clinicaltrials.gov\/show\/NCT00462540"},{"issue":"3","key":"10.1002\/14651858.CD013381.pub2-BIB0056|cit56","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1185\/03007990802708152","article-title":"Nebulised formoterol effect on bronchodilation and satisfaction in COPD patients compared to QID ipratropium\/albuterol MDI","volume":"25","author":"Sutherland","year":"2009","journal-title":"Current Medical Research and Opinion"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0057|cit57","unstructured":"The effect on self-care and self-efficacy of inhaler training in COPD clinicaltrials.gov\/show\/nct04052906"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0058|cit58","first-page":"A1604","article-title":"Therapeutic effect of switching tiotropium Handihaler To Respimat Soft MistTM; inhaler in the patients with COPD: the difference of adverse events and adherence to manipulations between inhaler devices","volume":"183","author":"Nishimura","year":"2011","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"issue":"1","key":"10.1002\/14651858.CD013381.pub2-BIB0059|cit59","first-page":"28","article-title":"Effects of inpatient drug counseling on compliance of asthmatic and COPD patients","volume":"15","author":"Pongchaidecha","year":"2005","journal-title":"Thai Journal of Hospital Pharmacy"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0060|cit60","unstructured":"Teaching use of respiratory inhalers (TURI) clinicaltrials.gov\/ct2\/show\/NCT01456494"},{"issue":"10","key":"10.1002\/14651858.CD013381.pub2-BIB0061|cit61","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1007\/s11606-012-2090-9","article-title":"Teaching the use of respiratory inhalers to hospitalised patients with asthma or COPD: a randomized trial","volume":"27","author":"Press","year":"2012","journal-title":"Journal of General Internal Medicine"},{"issue":"6","key":"10.1002\/14651858.CD013381.pub2-BIB0062|cit62","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1513\/AnnalsATS.201509-603OC","article-title":"Effectiveness of interventions to teach metered-dose and diskus inhaler techniques: a randomized trial","volume":"13","author":"Press","year":"2016","journal-title":"Annals of the American Thoracic Society"},{"issue":"4","key":"10.1002\/14651858.CD013381.pub2-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"632A","DOI":"10.1016\/j.chest.2016.08.724","article-title":"Patient education with inhaler technique to prevent readmissions and emergency room (ER) visits in asthma and COPD: a quality improvement project at an inner-city hospital","volume":"150","author":"Riar","year":"2016","journal-title":"Chest"},{"issue":"4","key":"10.1002\/14651858.CD013381.pub2-BIB0064|cit64","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1089\/jamp.2007.0634","article-title":"Handling of and preferences for available dry powder inhaler systems by patients with asthma and COPD","volume":"21","author":"Schulte","year":"2008","journal-title":"Journal of Aerosol Medicine and Pulmonary Drug Delivery"},{"issue":"10","key":"10.1002\/14651858.CD013381.pub2-BIB0065|cit65","first-page":"S77","article-title":"A randomized clinical trial of medication therapy management in a commercial population","volume":"21","author":"Smith-McLallen","year":"2015","journal-title":"Journal of Managed Care and Specialty Pharmacy"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0066|cit66","first-page":"P347E","article-title":"Effectiveness and economics of a formulary switch from two separate inhalation aerosols to 2-in-1 Combivent inhaler in a veteran COPD population","volume":"33","author":"Sung","year":"1998","journal-title":"American Journal of Health-System Pharmacy"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0067|cit67","doi-asserted-by":"crossref","first-page":"A161","DOI":"10.1136\/thoraxjnl-2011-201054c.229","article-title":"Factors affecting inhaler choice and adherence in urban Liverpool","volume":"66","author":"Tack","year":"2011","journal-title":"Thorax"},{"issue":"2","key":"10.1002\/14651858.CD013381.pub2-BIB0068|cit68","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1378\/chest.104.2.501","article-title":"Improving inhaler adherence in a clinical trial through the use of the Nebuliser Chronolog","volume":"104","author":"Nides","year":"1993","journal-title":"Chest"},{"issue":"3","key":"10.1002\/14651858.CD013381.pub2-BIB0069|cit69","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1006\/pmed.1993.1025","article-title":"Design and results of the initial intervention program for the Lung Health Study. The Lung Health Study Research Group","volume":"22","author":"O'Hara","year":"1993","journal-title":"Preventative medicine"},{"issue":"2","key":"10.1002\/14651858.CD013381.pub2-BIB0070|cit70","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1164\/ajrccm.152.2.7633711","article-title":"Long-term metered-dose inhaler adherence in a clinical trial. The Lung Health Study Research Group","volume":"152","author":"Rand","year":"1995","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"issue":"6","key":"10.1002\/14651858.CD013381.pub2-BIB0071|cit71","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1164\/ajrccm\/146.6.1559","article-title":"Metered-dose inhaler adherence in a clinical trial","volume":"146","author":"Rand","year":"1992","journal-title":"American Review of Respiratory Disease"},{"issue":"4","key":"10.1002\/14651858.CD013381.pub2-BIB0072|cit72","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1378\/chest.109.4.963","article-title":"Trends in compliance with bronchodilator inhaler use between follow-up visits in a clinical trial","volume":"109","author":"Simmons","year":"1996","journal-title":"Chest"},{"issue":"4","key":"10.1002\/14651858.CD013381.pub2-BIB0073|cit73","doi-asserted-by":"crossref","first-page":"33S","DOI":"10.1016\/0002-9343(91)90260-5","article-title":"A nebulizer chronolog to monitor compliance with inhaler use","volume":"91","author":"Tashkin","year":"1991","journal-title":"American Journal of Medicine"},{"issue":"1","key":"10.1002\/14651858.CD013381.pub2-BIB0074|cit74","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s12160-012-9355-8","article-title":"The influence of informal caregivers on adherence in COPD patients","volume":"44","author":"Trivedi","year":"2012","journal-title":"Annals of Behavioral Medicine"},{"issue":"5","key":"10.1002\/14651858.CD013381.pub2-BIB0075|cit75","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.jaip.2016.04.006","article-title":"Respiratory medication adherence: toward a common language and a shared vision","volume":"4","author":"Van Ganse","year":"2016","journal-title":"Journal of Allergy and Clinical Immunology in Practice"},{"issue":"3","key":"10.1002\/14651858.CD013381.pub2-BIB0076|cit76","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3109\/02770900009055445","article-title":"Compliance during long-term treatment with fluticasone propionate in subjects with early signs of asthma or chronic obstructive pulmonary disease: results of the detection, intervention, and monitoring programme of COPD and asthma (DIMCA) study","volume":"37","author":"Van Grunsven","year":"2000","journal-title":"Journal of Asthma"},{"issue":"1","key":"10.1002\/14651858.CD013381.pub2-BIB0077|cit77","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.2147\/COPD.S119849","article-title":"Impact of a care pathway for COPD on adherence to guidelines and hospital readmission: a cluster randomized trial","volume":"11","author":"Vanhaecht","year":"2016","journal-title":"International Journal of COPD"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0078|cit78","doi-asserted-by":"crossref","unstructured":"Vanhaecht K Sermeus W Peers J Lodewijckx C Deneckere S Leigheb F The impact of care pathways for exacerbation of chronic obstructive pulmonary disease: rationale and design of a cluster randomized controlled trial Trials 2010 11 111 1 7","DOI":"10.1186\/1745-6215-11-111"},{"issue":"2","key":"10.1002\/14651858.CD013381.pub2-BIB0079|cit79","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1345\/aph.1E027","article-title":"Effectiveness of interventions by community pharmacists to improve patient adherence to chronic medication: a systematic review","volume":"39","author":"Van Wijk","year":"2005","journal-title":"Annals of Pharmacotherapy"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0080|cit80","unstructured":"Vestbo J Anderson J Calverley P Celli B Ferguson G Jenkins C Adherence to medication, mortality and severe exacerbations in the TORCH study European Respiratory Society 18th Annual Congress; 2008 Oct 3-7; Berlin 2008 383"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0081|cit81","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1136\/thx.2009.113662","article-title":"Adherence to inhaled therapy, mortality and hospital admission in COPD","volume":"64","author":"Vestbo","year":"2009","journal-title":"Thorax"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0082|cit82","unstructured":"Vestbo J Anderson JA Willits LR Celli B Ferguson GT Jenkins CR The TOwards a Revolution in COPD Health (TORCH) study, the effects of compliance on mortality over 3 years American Thoracic Society International Conference; 2008 May 16-21; Toronto"},{"issue":"2","key":"10.1002\/14651858.CD013381.pub2-BIB0083|cit83","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1183\/09031936.04.00120603","article-title":"The TORCH (towards a revolution in COPD health) survival study protocol","volume":"24","author":"Vestbo","year":"2004","journal-title":"European Respiratory Journal"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0084|cit84","first-page":"25s","article-title":"A realistic study assessing inhaled treatment compliance in COPD patients","volume":"18","author":"Viejo","year":"2001","journal-title":"European Respiratory Journal"},{"issue":"7","key":"10.1002\/14651858.CD013381.pub2-BIB0085|cit85","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.rmed.2011.01.013","article-title":"Dose counter performance of mometasone furoate\/formoterol inhalers in subjects with asthma or COPD","volume":"105","author":"Weinstein","year":"2011","journal-title":"Respiratory Medicine"},{"issue":"2","key":"10.1002\/14651858.CD013381.pub2-BIB0086|cit86","doi-asserted-by":"crossref","first-page":"111","DOI":"10.5578\/tt.8975","article-title":"Acute exacerbation in COPD and asthma","volume":"63","author":"Yildirim","year":"2015","journal-title":"Tuberkuloz ve Toraks"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0087|cit87","unstructured":"Medication adherence management in a community pharmacy setting (AdherenciaMED): a cluster randomised controlled trial ictrptest.azurewebsites.net\/Trial2.aspx?TrialID=ACTRN12618000410257"},{"issue":"3","key":"10.1002\/14651858.CD013381.pub2-BIB0088|cit88","first-page":"e24","article-title":"Pharmacist-led medication intervention for patients with asthma and COPD within a primary care setting","volume":"58","author":"Bookser","year":"2018","journal-title":"Journal of the American Pharmacists Association"},{"issue":"1","key":"10.1002\/14651858.CD013381.pub2-BIB0089|cit89","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1186\/s13063-016-1623-7","article-title":"Effectiveness of a pharmacist-driven intervention in COPD (EPIC): study protocol for a randomized controlled trial","volume":"17","author":"Davis","year":"2016","journal-title":"Trials"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0090|cit90","doi-asserted-by":"crossref","unstructured":"Boyd M Waring J Barber N Mehta R Chuter A Protocol for the new medicine service study: a randomised controlled trial and economic evaluation with qualitative appraising comparing the effectiveness and cost-effectiveness of the new medicine service in community pharmacies in England Trials 2013 14 411","DOI":"10.1186\/1745-6215-14-411"},{"issue":"10","key":"10.1002\/14651858.CD013381.pub2-BIB0091|cit91","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1136\/bmjqs-2015-004400","article-title":"Supporting adherence for people starting a new medication for a long-term condition through community pharmacies: a pragmatic randomised controlled trial of the new medicine service","volume":"25","author":"Elliott","year":"2016","journal-title":"British Medical Journal Quality and Safety"},{"issue":"4","key":"10.1002\/14651858.CD013381.pub2-BIB0092|cit92","first-page":"286","article-title":"New medicine service: supporting adherence in people starting a new medication for a long-term condition: 26-week follow-up of a pragmatic randomised controlled trial","volume":"29","author":"Elliott","year":"2020","journal-title":"British Medical Journal"},{"issue":"12","key":"10.1002\/14651858.CD013381.pub2-BIB0093|cit93","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1007\/s40273-017-0554-9","article-title":"Cost-effectiveness of support for people starting a new medication for a long-term condition through community pharmacies: an economic evaluation of the new medicine service (NMS) compared with normal practice","volume":"35","author":"Elliott","year":"2017","journal-title":"Pharmacoeconomics"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0094|cit94","unstructured":"Understanding and appraising the new medicine service in England (NMS) https:\/\/clinicaltrials.gov\/ct2\/show\/NCT01635361 2012"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0095|cit95","unstructured":"Description of the ability to learn how to handle inhaler devices in COPD ictrptest.azurewebsites.net\/Trial2.aspx?TrialID=EUCTR2016-001435-13-FR"},{"issue":"1","key":"10.1002\/14651858.CD013381.pub2-BIB0096|cit96","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/1745-6215-15-109","article-title":"Evaluation of a tailored implementation strategy to improve the management of patients with chronic obstructive pulmonary disease in primary care: a study protocol of a cluster randomized trial","volume":"15","author":"Godycki-Cwirko","year":"2014","journal-title":"Trials"},{"issue":"6","key":"10.1002\/14651858.CD013381.pub2-BIB0097|cit97","doi-asserted-by":"publisher","first-page":"e204","DOI":"10.2196\/resprot.7522","article-title":"Does a tailored intervention to promote adherence in patients with chronic obstructive pulmonary disease affect exacerbations? A randomised controlled trial","volume":"23","author":"Gregoriano","year":"2019","journal-title":"Respiratory Research"},{"issue":"20","key":"10.1002\/14651858.CD013381.pub2-BIB0098|cit98","first-page":"273","article-title":"Impact of an electronic monitoring intervention to improve adherence to inhaled medication in patients with asthma and chronic obstructive pulmonary disease","volume":"3","author":"Gregoriano","year":"2017","journal-title":"JMIR Research Protocols"},{"issue":"6","key":"10.1002\/14651858.CD013381.pub2-BIB0099|cit99","first-page":"486","article-title":"Objective adherence to inhaled medication and health-related outcomes in asthma and chronic obstructive pulmonary disease after an electronic monitoring intervention","volume":"95","author":"Gregoriano","year":"2018","journal-title":"Respiration"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0100|cit100","first-page":"PA1061","article-title":"Patients' adherence to chronic treatment of pulmonary diseases","volume":"46","author":"Gregoriano","year":"2015","journal-title":"European Respiratory Journal"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0101|cit101","first-page":"127","article-title":"How do patients adhere to chronic treatment of pulmonary diseases? Baseline data from an adherence study","volume":"104","author":"Gregoriano","year":"2015","journal-title":"Praxis"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0102|cit102","first-page":"91S","article-title":"How do patients adhere to chronic treatment of pulmonary diseases? Preliminary data from a randomized controlled trial","volume":"0","author":"Gregoriano","year":"2016","journal-title":"Kardiovaskulare Medizin"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0103|cit103","unstructured":"Intervention to improve inhalative adherence clinicaltrials.gov\/ct2\/show\/NCT02386722"},{"issue":"1","key":"10.1002\/14651858.CD013381.pub2-BIB0104|cit104","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.pec.2003.08.007","article-title":"Effectiveness of an education programme by a general practice assistant for asthma and COPD patients: results from a randomised controlled trial","volume":"55","author":"Hesselink","year":"2004","journal-title":"Patient Education and Counselling"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0105|cit105","unstructured":"Study of inhaler use in asthma and COPD ictrptest.azurewebsites.net\/Trial2.aspx?TrialID=ISRCTN10844309"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0106|cit106","unstructured":"Minimal interventions to improve medication adherence in people with multiple long-term conditions (MINIMA) study ictrptest.azurewebsites.net\/Trial2.aspx?TrialID=ISRCTN62025354"},{"issue":"2","key":"10.1002\/14651858.CD013381.pub2-BIB0107|cit107","doi-asserted-by":"crossref","first-page":"1","DOI":"10.24926\/iip.v8i2.512","article-title":"Collaboration between hospital and community pharmacists to improve medication management from hospital to home","volume":"8","author":"Kristeller","year":"2017","journal-title":"Innovations in Pharmacy"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0108|cit108","unstructured":"Improving medication adherence through a transitional care pharmacy practice model www.clinicaltrials.gov\/ct2\/show\/NCT02047448"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0109|cit109","doi-asserted-by":"crossref","first-page":"e022685","DOI":"10.1136\/bmjopen-2018-022685","article-title":"Inhaler technique education in elderly patients with asthma or COPD: impact on disease exacerbations-a protocol for a single-blinded randomised controlled trial","volume":"9","author":"Maricoto","year":"2019","journal-title":"BMJ Open"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0110|cit110","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1345\/aph.1H256","article-title":"Influence of an interactive computer-based inhaler technique tutorial on patient knowledge and inhaler technique","volume":"41","author":"Navarre","year":"2007","journal-title":"Annals of Pharmacotherapy"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0111|cit111","unstructured":"Intervention to improve the adherence in community pharmacies clinicaltrials.gov\/ct2\/show\/NCT04195191"},{"issue":"7","key":"10.1002\/14651858.CD013381.pub2-BIB0112|cit112","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1177\/106002809302700721","article-title":"Assessment of patient acceptance and inhalation technique of a pressurized aerosol inhaler and two breath-actuated devices","volume":"27","author":"Nimmo","year":"1993","journal-title":"Annals of Pharmacotherapy"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0113|cit113","doi-asserted-by":"publisher","first-page":"PA5006","DOI":"10.1183\/13993003congress-2016.PA5006","article-title":"Inhalation technique education in asthma or COPD: the value of a visual instruction card","volume":"48","author":"Kemerink","year":"2016","journal-title":"European Respiratory Journal"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0114|cit114","unstructured":"Teaching inhaler use with the INCA device in a community pharmacy setting www.clinicaltrials.gov\/ct2\/show\/NCT02203266"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0115|cit115","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.jaip.2019.09.008","article-title":"Personalised biofeedback on inhaler adherence and technique by community pharmacists: a cluster randomised clinical trial","volume":"8","author":"O'Dwyer","year":"2020","journal-title":"Journal of Allergy and Clinical Immunology Practice"},{"issue":"5","key":"10.1002\/14651858.CD013381.pub2-BIB0116|cit116","first-page":"413","article-title":"Evaluation and analysis of inhaler drug device adherence in asthma and COPD patients","volume":"51","author":"Qin","year":"2016","journal-title":"Chinese Pharmaceutical Journal"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0117|cit117","unstructured":"The role of the pharmacist in the team care of hospitalised patients with chronic bronchitis or emphysema ictrptest.azurewebsites.net\/Trial2.aspx?TrialID=RBR-5bw2wt"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0118|cit118","unstructured":"SAM30001 GSK Compliance in asthma and COPD www.gsk-studyregister.com\/en\/trial-details\/?id=SAM30001#documents-section"},{"issue":"1","key":"10.1002\/14651858.CD013381.pub2-BIB0119|cit119","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1089\/08942680252908584","article-title":"Patient perception and acceptability of multidose dry powder inhalers: a randomized crossover comparison of Diskus\/Accuhaler with Turbuhaler","volume":"15","author":"Serra-Batlles","year":"2002","journal-title":"Journal of Aerosol Medicine"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0120|cit120","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.sapharm.2017.10.008","article-title":"Structured pharmacist-led intervention programme to improve medication adherence in COPD patients: a randomised controlled trial","volume":"14","author":"Abdulsalim","year":"2018","journal-title":"Research in Social and Administrative Pharmacy"},{"issue":"1","key":"10.1002\/14651858.CD013381.pub2-BIB0121|cit121","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/jcpt.12353","article-title":"Effectiveness of clinical pharmacist intervention on health-related quality of life in chronic obstructive pulmonary disorder patients - a randomized controlled study","volume":"41","author":"Suhaj","year":"2016","journal-title":"Journal of Clinical Pharmacy and Therapeutics"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0122|cit122","first-page":"58","article-title":"The effectiveness of clinical pharmacist intervention on health related quality of life in chronic obstructive pulmonary disorder patients - a randomized controlled study","volume":"20","author":"Suhaj","year":"2015","journal-title":"Respirology"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0123|cit123","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.2147\/PPA.S110167","article-title":"The impact of pharmacist-managed clinic on medication adherence and health-related quality of life in patients with COPD: a randomized controlled study","volume":"10","author":"Xin","year":"2016","journal-title":"Patient Preference and Adherence"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0124|cit124","unstructured":"Maximising adherence and gaining new information for your COPD ictrptest.azurewebsites.net\/Trial2.aspx?TrialID=ISRCTN10567920"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0125|cit125","unstructured":"Using the internet to help individuals stay healthy and prevent further reductions in health from existing chronic diseases ictrptest.azurewebsites.net\/Trial2.aspx?TrialID=ISRCTN10567920"},{"issue":"2","key":"10.1002\/14651858.CD013381.pub2-BIB0126|cit126","doi-asserted-by":"crossref","first-page":"297","DOI":"10.4187\/respcare.03123","article-title":"Relationship between medication adherence and health related quality of life in subjects with COPD: a systematic review","volume":"60","author":"\u00c1gh","year":"2015","journal-title":"Respiratory Care"},{"issue":"3","key":"10.1002\/14651858.CD013381.pub2-BIB0127|cit127","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1513\/AnnalsATS.201509-600PS","article-title":"Why don't our patients with chronic obstructive pulmonary disease listen to us?","volume":"13","author":"Blackstock","year":"2016","journal-title":"Annals of the American Thoracic Society"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0128|cit128","doi-asserted-by":"crossref","first-page":"1801147","DOI":"10.1183\/13993003.01147-2018","article-title":"Digital technologies and adherence in respiratory diseases: the road ahead","volume":"52","author":"Blakey","year":"2018","journal-title":"European Respiratory Journal"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0129|cit129","unstructured":"Healthcare professionals as bad as patients at good respiratory inhaler technique: editorial www.sciencedaily.com\/releases\/2012\/10\/121003195134.htm"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0130|cit130","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s13601-017-0175-6","article-title":"Differences in medication adherence are associated with beliefs about medicines in asthma and COPD","volume":"7","author":"Brandstetter","year":"2017","journal-title":"Clinical and Translational Allergy"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0131|cit131","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/1465-9921-14-109","article-title":"Improving medication adherence in chronic obstructive pulmonary disease: a systematic review","volume":"14","author":"Bryant","year":"2013","journal-title":"Respiratory Research"},{"issue":"1","key":"10.1002\/14651858.CD013381.pub2-BIB0132|cit132","doi-asserted-by":"publisher","first-page":"1700393","DOI":"10.1183\/13993003.00393-2017","article-title":"Excess economic burden of co-morbidities in COPD: a 15 year population-based study","volume":"50","author":"Chen","year":"2017","journal-title":"European Respiratory Journal"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0133|cit133","unstructured":"Cochrane Airways Trials Register airways.cochrane.org\/trials-register"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0134|cit134","unstructured":"COPD Foundation What is COPD? www.copdfoundation.org\/What-is-COPD\/Understanding-COPD\/What-is-COPD.aspx"},{"issue":"1","key":"10.1002\/14651858.CD013381.pub2-BIB0135|cit135","doi-asserted-by":"crossref","first-page":"30","DOI":"10.7326\/M18-0543","article-title":"ESPACOMP Medication Adherence Reporting Guideline (EMERGE)","volume":"169","author":"De Geest","year":"2018","journal-title":"Annals of Internal Medicine"},{"issue":"10","key":"10.1002\/14651858.CD013381.pub2-BIB0136|cit136","doi-asserted-by":"crossref","first-page":"493","DOI":"10.12968\/pnur.2015.26.10.493","article-title":"Medication adherence in chronic obstructive pulmonary disease","volume":"26","author":"Duncan","year":"2015","journal-title":"Practice Nursing"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0137|cit137","first-page":"17","article-title":"Pharmacotherapies for COPD","volume":"7","author":"Ejiofor","year":"2013","journal-title":"Clinical Medical Insights: Circulatory, Respiratory and Pulmonary Medicine"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0138|cit138","doi-asserted-by":"crossref","first-page":"k2801","DOI":"10.1136\/bmj.k2801","article-title":"Evidence and tips on the use of medication compliance aids","volume":"362","author":"Furmedge","year":"2018","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0139|cit139","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/S2213-2600(17)30293-X","article-title":"Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990-2015: a systematic analysis for the Global Burden of Disease study 2015","volume":"5","author":"Global Burden of Disease 2015 Chronic Respiratory Disease Collaborators","year":"2017","journal-title":"Lancet Respiratory Medicine"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0140|cit140","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/S0140-6736(16)31678-6","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015","volume":"388","author":"Global Burden of Disease 2015 Disease and Injury Incidence and Prevalence Collaborators","year":"2016","journal-title":"Lancet"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0141|cit141","unstructured":"Global Initiative for Chronic Obstructive Lung Disease GOLD 2021 global strategy for the diagnosis, management, and prevention of COPD goldcopd.org\/"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0142|cit142","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1136\/bmj.282.6282.2114","article-title":"Assessing clinical trials - restricted randomisation","volume":"282","author":"Gore","year":"1981","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0143|cit143","unstructured":"McMaster University (developed by Evidence Prime) GRADEpro GDT 2015"},{"issue":"10","key":"10.1002\/14651858.CD013381.pub2-BIB0144|cit144","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009764.pub3","article-title":"Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD)","author":"Herath","year":"2018","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0145|cit145","doi-asserted-by":"crossref","DOI":"10.1002\/9781119536604","volume-title":"Cochrane Handbook for Systematic Reviews of Interventions","author":"Higgins","year":"2019"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0146|cit146","first-page":"163","article-title":"Adherence to inhaled therapy and its impact on chronic obstructive pulmonary disease (COPD)","volume":"18","author":"Humenberger","year":"2018","journal-title":"BioMed Central Pulmonary Medicine"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0147|cit147","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1081\/COPD-200050513","article-title":"St. George\u2019s Respiratory Questionnaire: MCID","volume":"2","author":"Jones","year":"2005","journal-title":"Journal of Chronic Obstructive Pulmonary Disease"},{"issue":"36","key":"10.1002\/14651858.CD013381.pub2-BIB0148|cit148","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta19360","article-title":"Supported self-management for patients with moderate to severe chronic obstructive pulmonary disease (COPD): an evidence synthesis and economic analysis","volume":"19","author":"Jordan","year":"2015","journal-title":"Health Technology Assessment"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0149|cit149","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/s41533-017-0022-1","article-title":"Effectiveness and success factors of educational inhaler technique interventions in asthma & COPD patients: a systematic review","volume":"27","author":"Klijn","year":"2017","journal-title":"Primary Care Respiratory Medicine"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0150|cit150","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/1465-9921-7-62","article-title":"Health status measurement in COPD: the minimal clinically important difference of the clinical COPD questionnaire","volume":"7","author":"Kocks","year":"2006","journal-title":"Respiratory Research"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0151|cit151","first-page":"256","article-title":"Effect of a self-management program for patients with chronic disease","volume":"4","author":"Lorig","year":"2001","journal-title":"Effective Clinical Practice"},{"issue":"4","key":"10.1002\/14651858.CD013381.pub2-BIB0152|cit152","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1002\/jrsm.1287","article-title":"Machine learning for identifying randomized controlled trials: an evaluation and practitioner\u2019s guide","volume":"9","author":"Marshall","year":"2018","journal-title":"Research Synthesis Methods"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0153|cit153","unstructured":"McDonald S Noel-Storr AH Thomas J Harnessing the efficiencies of machine learning and Cochrane Crowd to identify randomised trials for individual Cochrane reviews Global Evidence Summit; 2017 Sept 13-16; Cape Town, South Africa"},{"issue":"7","key":"10.1002\/14651858.CD013381.pub2-BIB0154|cit154","doi-asserted-by":"publisher","first-page":"e1000097","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Medicine"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0155|cit155","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1161\/01.HYP.4.3.415","article-title":"Management of patient compliance in the treatment of hypertension","volume":"4","author":"National Heart","year":"1982","journal-title":"Hypertension"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0156|cit156","unstructured":"National Institute for Health and Care Excellence Chronic obstructive pulmonary disease in over 16s: diagnosis and management [CG101] www.nice.org.uk\/guidance\/cg101"},{"issue":"11","key":"10.1002\/14651858.CD013381.pub2-BIB0157|cit157","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000011","article-title":"Interventions for enhancing medication adherence","author":"Nieuwlaat","year":"2014","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0158|cit158","unstructured":"Noel-Storr AH Project Transform team Cochrane Crowd: new ways of working together to produce health evidence Evidence Live; 2018 Jun 18-20; Oxford, UK 2018"},{"issue":"4","key":"10.1002\/14651858.CD013381.pub2-BIB0159|cit159","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012226.pub2","article-title":"Interventions to improve adherence to inhaled steroids for asthma","author":"Normansell","year":"2017","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"5","key":"10.1002\/14651858.CD013381.pub2-BIB0160|cit160","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001287.pub6","article-title":"Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease","author":"Poole","year":"2019","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0161|cit161","doi-asserted-by":"crossref","first-page":"179","DOI":"10.7326\/0003-4819-155-3-201108020-00008","article-title":"Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society","volume":"155","author":"Qaseem","year":"2011","journal-title":"Annals of Internal Medicine"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0162|cit162","doi-asserted-by":"publisher","first-page":"e4","DOI":"10.1017\/gheg.2018.1","article-title":"The unmet global burden of COPD","volume":"3","author":"Quaderi","year":"2018","journal-title":"Global Health, Epidemiology and Genomics"},{"issue":"3","key":"10.1002\/14651858.CD013381.pub2-BIB0163|cit163","doi-asserted-by":"crossref","first-page":"371","DOI":"10.2147\/COPD.S3036","article-title":"Medication adherence issues in patients treated for COPD","volume":"3","author":"Restrepo","year":"2008","journal-title":"International Journal of Chronic Obstructive Pulmonary Disease"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0164|cit164","unstructured":"The Nordic Cochrane Centre, The Cochrane Collaboration Review Manager (RevMan) 2014"},{"issue":"5","key":"10.1002\/14651858.CD013381.pub2-BIB0165|cit165","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1089\/jamp.2009.0785","article-title":"Predictors of incorrect inhalation technique in patients with asthma or COPD: a study using a validated videotaped scoring method","volume":"23","author":"Rootmensen","year":"2010","journal-title":"Journal of Aerosol Medicine and Pulmonary Drug Delivery"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0166|cit166","unstructured":"Sabat\u00e9 E Adherence to long-term therapies: evidence for action https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/42682\/9241545992.pdf?sequence=1&isAllowed=y [accessed September 2021] 2003"},{"issue":"10","key":"10.1002\/14651858.CD013381.pub2-BIB0167|cit167","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1164\/rccm.201604-0733OC","article-title":"Objective assessment of adherence to inhalers by patients with chronic obstructive pulmonary disease","volume":"195","author":"Sulaiman","year":"2017","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0168|cit168","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jclinepi.2017.08.011","article-title":"Living systematic review network. Living systematic reviews: 2. Combining human and machine effort","volume":"91","author":"Thomas","year":"2017","journal-title":"Journal of Clinical Epidemiology"},{"issue":"1","key":"10.1002\/14651858.CD013381.pub2-BIB0169|cit169","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.rmed.2013.08.044","article-title":"Clinical and economic impact of non-adherence in COPD: a systematic review","volume":"108","author":"Van Boven","year":"2014","journal-title":"Respiratory Medicine"},{"issue":"4","key":"10.1002\/14651858.CD013381.pub2-BIB0170|cit170","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1164\/rccm.201204-0596PP","article-title":"Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease: GOLD executive summary","volume":"187","author":"Vestbo","year":"2013","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"issue":"5","key":"10.1002\/14651858.CD013381.pub2-BIB0171|cit171","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1164\/rccm.201701-0218PP","article-title":"Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report: GOLD executive summary","volume":"195","author":"Vogelmeier","year":"2017","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"issue":"5","key":"10.1002\/14651858.CD013381.pub2-BIB0172|cit172","first-page":"802","article-title":"What we mean when we talk about adherence in respiratory medicine","volume":"4","author":"Vrijens","year":"2016","journal-title":"Journal of Allergy and Clinical Immunology: In Practice"},{"issue":"9","key":"10.1002\/14651858.CD013381.pub2-BIB0173|cit173","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001288.pub4","article-title":"Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease","author":"Walters","year":"2014","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0174|cit174","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1183\/13993003.00535-2015","article-title":"The minimal important difference for the St George\u2019s Respiratory Questionnaire in patients with severe COPD","volume":"46","author":"Welling","year":"2015","journal-title":"European Respiratory Journal"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0175|cit175","unstructured":"World Health Organization Adherence to long-term therapies: evidence for action apps.who.int\/medicinedocs\/pdf\/s4883e\/s4883e.pdf"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0176|cit176","unstructured":"World Health Organization Chronic obstructive pulmonary disease (COPD) www.who.int\/en\/news-room\/fact-sheets\/detail\/chronic-obstructive-pulmonary-disease-(copd)"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0177|cit177","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1136\/thx.49.5.465","article-title":"Reliability and validity of the chronic respiratory questionnaire (CRQ)","volume":"49","author":"Wijkstra","year":"1994","journal-title":"Thorax"},{"key":"10.1002\/14651858.CD013381.pub2-BIB0178|cit178","first-page":"96","article-title":"Factors influencing adherence to treatment in COPD patients and its relationship with disease exacerbations","volume":"82","author":"Wi\u015bniewski","year":"2014","journal-title":"Pneumonologia i Alergologia Polska"},{"issue":"6","key":"10.1002\/14651858.CD013381.pub2-BIB0179|cit179","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1007\/s11096-014-0024-9","article-title":"Evaluation of pharmacist care for patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis","volume":"36","author":"Zhong","year":"2014","journal-title":"International Journal of Clinical Pharmacy"},{"issue":"8","key":"10.1002\/14651858.CD013381.pub2-BIB0180|cit180","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD013381","article-title":"Interventions to improve adherence to pharmacological therapy for chronic obstructive pulmonary disease (COPD)","author":"Janjua","year":"2019","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,2,7]],"date-time":"2023-02-07T04:49:28Z","timestamp":1675745368000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD013381.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Airways Group","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,9,8]]},"references-count":180,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2021,9]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd013381.pub2","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,8]]}}}