{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T08:48:09Z","timestamp":1791967689872,"version":"4.3.4"},"update-to":[{"DOI":"10.1002\/14651858.cd014617.pub2","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:00:00Z","timestamp":1759104000000}}],"reference-count":53,"publisher":"Wiley","issue":"9","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd014617.pub3","type":"journal-article","created":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T11:08:53Z","timestamp":1759144133000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Antibiotic prophylaxis for corneal abrasion"],"prefix":"10.1002","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2837-8403","authenticated-orcid":false,"given":"Sueko M","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology; University of Colorado Anschutz Medical Campus; Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Leslie","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology; University of Colorado Anschutz Medical Campus; Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Chen","family":"Tzang","sequence":"additional","affiliation":[{"name":"School of Medicine; National Taiwan University; Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah M","family":"Algarni","sequence":"additional","affiliation":[{"name":"Family Medicine Department; Aseer Central Hospital; Abha Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene C","family":"Kuo","sequence":"additional","affiliation":[{"name":"Wilmer Eye Institute; The Johns Hopkins University School of Medicine; Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annali L","family":"Lawrenson","sequence":"additional","affiliation":[{"name":"Emergency Department; Epsom General Hospital; Surrey UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"supported by the Cochrane Eyes and Vision Review Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,29]]},"reference":[{"key":"10.1002\/14651858.CD014617.pub3-BIB0001|cit1","first-page":"167","volume-title":"Kanski's Clinical Ophthalmology: A Systematic Approach","author":"Bowling","year":"2016"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0002|cit2","first-page":"155","volume-title":"Ophthalmology","author":"Farjo","year":"2019"},{"issue":"2","key":"10.1002\/14651858.CD014617.pub3-BIB0003|cit3","first-page":"114","article-title":"Evaluation and management of corneal abrasions","volume":"87","author":"Wipperman","year":"2013","journal-title":"American Family Physician"},{"issue":"5","key":"10.1002\/14651858.CD014617.pub3-BIB0004|cit4","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/j.jopan.2006.08.001","article-title":"Detection and treatment of perioperative corneal abrasions","volume":"21","author":"Moos","year":"2006","journal-title":"Journal of PeriAnesthesia Nursing"},{"issue":"7","key":"10.1002\/14651858.CD014617.pub3-BIB0005|cit5","first-page":"544","article-title":"A comparison of eye problems in primary care and ophthalmology practices","volume":"23","author":"Shields","year":"1991","journal-title":"Family Medicine"},{"issue":"12","key":"10.1002\/14651858.CD014617.pub3-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.15537\/1658-3175.5440","article-title":"One month outcome of ocular related emergencies in a tertiary hospital in Central Saudi Arabia","volume":"32","author":"Alotaibi","year":"2011","journal-title":"Saudi Medical Journal"},{"issue":"1","key":"10.1002\/14651858.CD014617.pub3-BIB0007|cit7","first-page":"123","article-title":"Management of corneal abrasions","volume":"70","author":"Wilson","year":"2004","journal-title":"American Family Physician"},{"issue":"4","key":"10.1002\/14651858.CD014617.pub3-BIB0008|cit8","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1136\/bjo.85.4.388","article-title":"The Bhaktapur eye study: ocular trauma and antibiotic prophylaxis for the prevention of corneal ulceration in Nepal","volume":"85","author":"Upadhyay","year":"2001","journal-title":"British Journal of Ophthalmology"},{"issue":"8","key":"10.1002\/14651858.CD014617.pub3-BIB0009|cit9","doi-asserted-by":"publisher","first-page":"440","DOI":"10.12968\/bjon.1995.4.8.440","article-title":"Nurse management of corneal abrasion","volume":"4","author":"Knox","year":"1995","journal-title":"British Journal of Nursing"},{"issue":"2","key":"10.1002\/14651858.CD014617.pub3-BIB0010|cit10","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1007\/s00417-007-0738-7","article-title":"Eye injuries in an Italian urban population: report of 10,620 cases admitted to an eye emergency department in Torino","volume":"246","author":"Fea","year":"2008","journal-title":"Graefe's Archive for Clinical & Experimental Ophthalmology"},{"issue":"Pt 5","key":"10.1002\/14651858.CD014617.pub3-BIB0011|cit11","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1038\/eye.1998.220","article-title":"The epidemiology of ocular injury in a major US automobile corporation","volume":"12","author":"Wong","year":"1998","journal-title":"Eye"},{"issue":"5","key":"10.1002\/14651858.CD014617.pub3-BIB0012|cit12","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009781.pub2","article-title":"Topical non-steroidal anti-inflammatory drugs for analgesia in traumatic corneal abrasions","author":"Wakai","year":"2017","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"4","key":"10.1002\/14651858.CD014617.pub3-BIB0013|cit13","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1007\/s10792-012-9698-y","article-title":"Controversies in ocular trauma classification and management: review","volume":"33","author":"Agrawal","year":"2013","journal-title":"International Ophthalmology"},{"issue":"11","key":"10.1002\/14651858.CD014617.pub3-BIB0014|cit14","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD011426.pub2","article-title":"Topical antibiotics for preventing surgical site infection in wounds healing by primary intention","author":"Heal","year":"2016","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"5","key":"10.1002\/14651858.CD014617.pub3-BIB0015|cit15","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1136\/emj.15.5.352","article-title":"Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Antibiotics and corneal abrasion","volume":"15","author":"Dollery","year":"1998","journal-title":"Journal of Accident & Emergency Medicine"},{"issue":"4","key":"10.1002\/14651858.CD014617.pub3-BIB0016|cit16","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1136\/emj.18.4.273","article-title":"Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Mydriatics in corneal abrasion","volume":"81","author":"Carley","year":"2001","journal-title":"Emergency Medicine Journal"},{"issue":"7","key":"10.1002\/14651858.CD014617.pub3-BIB0017|cit17","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004764.pub3","article-title":"Patching for corneal abrasion","author":"Lim","year":"2016","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"32","key":"10.1002\/14651858.CD014617.pub3-BIB0018|cit18","doi-asserted-by":"publisher","first-page":"865","DOI":"10.15585\/mmwr.mm6432a2","article-title":"Contact lens wearer demographics and risk behaviors for contact lens-related eye infections--United States, 2014","volume":"64","author":"Cope","year":"2015","journal-title":"MMWR - Morbidity & Mortality Weekly Report"},{"issue":"1","key":"10.1002\/14651858.CD014617.pub3-BIB0019|cit19","doi-asserted-by":"publisher","first-page":"P1","DOI":"10.1016\/j.ophtha.2018.10.018","article-title":"Bacterial Keratitis Preferred Practice Pattern\u00ae","volume":"126","author":"Lin","year":"2019","journal-title":"Ophthalmology"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0020|cit20","unstructured":"Clinical management guidelines. Corneal abrasion https:\/\/www.college-optometrists.org\/clinical-guidance\/clinical-management-guidelines\/cornealabrasion"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0021|cit21","unstructured":"National Institute for Health and Care Excellence Corneal superficial injury: topical antibiotics https:\/\/cks.nice.org.uk\/topics\/corneal-superficial-injury\/prescribing-information\/topical-antibiotics\/"},{"issue":"2","key":"10.1002\/14651858.CD014617.pub3-BIB0022|cit22","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.sjopt.2017.10.007","article-title":"Management of traumatic corneal abrasion by a sample of practicing ophthalmologists in Saudi Arabia","volume":"32","author":"Al-Saleh","year":"2018","journal-title":"Saudi Journal of Ophthalmology"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0023|cit23","first-page":"790","volume-title":"Rosen's Emergency Medicine: Concepts and Clinical Practice","volume":"I","author":"Guluma","year":"2018"},{"issue":"6","key":"10.1002\/14651858.CD014617.pub3-BIB0024|cit24","first-page":"934","article-title":"Emergency eye injuries","volume":"19","author":"Kruger","year":"1990","journal-title":"Australian Family Physician"},{"issue":"8","key":"10.1002\/14651858.CD014617.pub3-BIB0025|cit25","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD015091.pub2","article-title":"Topical ophthalmic anesthetics for corneal abrasions","author":"Sulewski","year":"2023","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"5","key":"10.1002\/14651858.CD014617.pub3-BIB0026|cit26","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD014617.pub2","article-title":"Antibiotic prophylaxis for corneal abrasion","author":"Algarni","year":"2022","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0027|cit27","doi-asserted-by":"publisher","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0028|cit28","unstructured":"Core Outcome Measures in Effectiveness Trials https:\/\/www.comet-initiative.org\/"},{"issue":"2","key":"10.1002\/14651858.CD014617.pub3-BIB0029|cit29","first-page":"129\u201338","article-title":"Pain assessment: global use of the brief pain inventory","volume":"23","author":"Cleeland","year":"1994","journal-title":"Annals of the Academy of Medicine, Singapore"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0030|cit30","unstructured":"Cochrane Database of Systematic Reviews: editorial policies Managing potentially problematic studies https:\/\/www.cochranelibrary.com\/cdsr\/editorial-policies#problematic-studies"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0031|cit31","unstructured":"National Library of Medicine PubMed https:\/\/pubmed.ncbi.nlm.nih.gov\/"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0032|cit32","unstructured":"The retraction watch database https:\/\/www.retractiondatabase.org\/RetractionSearch.aspx"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0033|cit33","unstructured":"Covidence Veritas Health Innovation 2025"},{"issue":"7","key":"10.1002\/14651858.CD014617.pub3-BIB0034|cit34","doi-asserted-by":"publisher","first-page":"e1000097","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Medicine"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0035|cit35","unstructured":"Review Manager The Cochrane Collaboration 2025"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0036|cit36","unstructured":"Higgins JPT Savovi\u0107 J Page MJ Elbers RG Sterne JAC Chapter 8: Assessing risk of bias in a randomized trial (chapter last updated October 2019). In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 6.5 (updated August 2024). Cochrane, 2024 Available from httpes:\/\/www.training.cochrane.org\/handbook"},{"issue":"1","key":"10.1002\/14651858.CD014617.pub3-BIB0037|cit37","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1034\/j.1600-0420.1998.760121.x","article-title":"Comparison of fucithalmic viscous eye drops and chloramphenicol eye ointment as a single treatment in corneal abrasion","volume":"76","author":"\u00a0Nissen","year":"1998","journal-title":"Acta Ophthalmologica Scandinavica"},{"issue":"6","key":"10.1002\/14651858.CD014617.pub3-BIB0038|cit38","first-page":"921-6","article-title":"The effect of topically applied sodium-hyaluronic acid (Na-HA) on corneal epithelial healing","volume":"37","author":"Chung","year":"1996","journal-title":"Journal of the Korean Ophthalmological Society"},{"issue":"37","key":"10.1002\/14651858.CD014617.pub3-BIB0039|cit39","first-page":"1444","article-title":"Foreign bodies in the eyes","volume":"71","author":"Adam","year":"1975","journal-title":"Nursing Times"},{"issue":"2","key":"10.1002\/14651858.CD014617.pub3-BIB0040|cit40","first-page":"55\u20136","article-title":"Foreign bodies in the eyes--an experiment","volume":"71","author":"Cutajar","year":"1975","journal-title":"Nursing Times"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0041|cit41","unstructured":"Clinical trial of comparison the effect of honey drop and ciprofloxacin drop in corneal ulcer https:\/\/trialsearch.who.int\/Trial2.aspx?TrialID=IRCT2015020120892N1"},{"issue":"3","key":"10.1002\/14651858.CD014617.pub3-BIB0042|cit42","doi-asserted-by":"publisher","first-page":"457","DOI":"10.2174\/1570163817666200214113055","article-title":"Efficacy of honey based ophthalmic formulation in patients with corneal ulcer; a randomized clinical trial","volume":"18","author":"Nejabat","year":"2021","journal-title":"Current Drug Discovery Technologies"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1097\/00003226-199301000-00026","article-title":"The effect of tobramycin soaked collagen shields in the treatment of corneal abrasion","volume":"12","author":"Palmon","year":"1993","journal-title":"Cornea"},{"issue":"7109","key":"10.1002\/14651858.CD014617.pub3-BIB0044|cit44","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"issue":"7304","key":"10.1002\/14651858.CD014617.pub3-BIB0045|cit45","doi-asserted-by":"publisher","first-page":"101\u20135","DOI":"10.1136\/bmj.323.7304.101","article-title":"Systematic reviews in health care: investigating and dealing with publication and other biases in meta-analysis","volume":"323","author":"Sterne","year":"2001","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0046|cit46","unstructured":"McKenzie JE Brennan SE Chapter 12: Synthesizing and presenting findings using other methods (chapter last updated October 2019). In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 6.5 (updated August 2024). Cochrane, 2024 Available from https:\/\/www.training.cochrane.org\/handbook"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0047|cit47","unstructured":"Deeks JJ Higgins JP Altman DG McKenzie JE Chapter 10: Analysing data and undertaking meta-analyses (chapter last updated November 2024). In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 6.5 (updated August 2024). Cochrane, 2024 Available from https:\/\/www.training.cochrane.org\/handbook"},{"issue":"1","key":"10.1002\/14651858.CD014617.pub3-BIB0048|cit48","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.jclinepi.2013.08.005","article-title":"Applying an equity lens to interventions: using PROGRESS ensures consideration of socially stratifying factors to illuminate inequities in health","volume":"67","author":"O'Neill","year":"2014","journal-title":"Journal of Clinical Epidemiology"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0049|cit49","unstructured":"The effects of lubricants versus chloramphenicol on corneal healing in patients with corneal abrasions www.anzctr.org.au\/Trial\/Registration\/TrialReview.aspx?ACTRN=12609000823279"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0050|cit50","unstructured":"Corneal abrasion https:\/\/www.cuh.nhs.uk\/patient-information\/corneal-abrasion\/"},{"key":"10.1002\/14651858.CD014617.pub3-BIB0051|cit51","unstructured":"Urgent care: corneal abrasion https:\/\/www.oxfordhealth.nhs.uk\/wp-content\/uploads\/2014\/08\/OP-142.15-Corneal-abrasion.pdf"},{"issue":"7","key":"10.1002\/14651858.CD014617.pub3-BIB0052|cit52","doi-asserted-by":"publisher","first-page":"e70035","DOI":"10.1111\/eci.70035","article-title":"The cost of emulated target trials: is real-world data cheaper than randomized studies?","volume":"55","author":"Barosa","year":"2025","journal-title":"European Journal of Clinical Investigation"},{"issue":"3","key":"10.1002\/14651858.CD014617.pub3-BIB0053|cit53","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD014617","article-title":"Antibiotic prophylaxisfor corneal abrasion","author":"Algarni","year":"2021","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T08:03:52Z","timestamp":1791965032000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD014617.pub3"}},"subtitle":[],"editor":[{"name":"Cochrane Central Editorial Service","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,9,29]]},"references-count":53,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2025,9]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd014617.pub3","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,29]]}}}