{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:15:13Z","timestamp":1786976113463,"version":"build-2736575974"},"update-to":[{"DOI":"10.1002\/14651858.cd015751","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T00:00:00Z","timestamp":1725494400000}}],"reference-count":131,"publisher":"Wiley","issue":"9","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd015751.pub2","type":"journal-article","created":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T07:23:23Z","timestamp":1725521003000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Lubricating drops for contact lens discomfort in adults"],"prefix":"10.1002","volume":"2024","author":[{"given":"Barbara","family":"Caffery","sequence":"additional","affiliation":[{"name":"Toronto Eye Care; Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew D","family":"Pucker","sequence":"additional","affiliation":[{"name":"School of Optometry; University of Alabama at Birmingham; Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ngozi C","family":"Chidi-Egboka","sequence":"additional","affiliation":[{"name":"School of Optometry and Vision Science, Faculty of Medicine and Health; The University of New South Wales; Sydney, NSW Australia"},{"name":"Save Sight Institute, Sydney Medical School, Faculty of Medicine and Health; The University of Sydney; Sydney, NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chukwuemeka Junior","family":"Obinwanne","sequence":"additional","affiliation":[{"name":"Cornea and Contact Lens Unit; De Lens Ophthalmics Family Eye and Vision Centre; Abuja Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brooke","family":"Harkness","sequence":"additional","affiliation":[{"name":"Casey Eye Institute; Oregon Health and Science University; Portland Oregon USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole A","family":"Carnt","sequence":"additional","affiliation":[{"name":"School of Optometry and Vision Science; Faculty of Medicine and Health, The University of New South Wales; Sydney, NSW Australia"},{"name":"Centre for Vision Research; Westmead Institute for Medical Research, University of Sydney; Westmead Australia"},{"name":"Institute of Ophthalmology; University College London; London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su-Hsun","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology; University of Colorado Anschutz Medical Campus; Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Ng","sequence":"additional","affiliation":[{"name":"Centre for Ocular Research &  Education (CORE), School of Optometry and Vision Science; University of Waterloo; Waterloo Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,5]]},"reference":[{"issue":"1","key":"10.1002\/14651858.CD015751.pub2-BIB0001|cit1","first-page":"45-50","article-title":"Effects of a 0.9% sodium chloride ophthalmic solution on the ocular surface of symptomatic contact lens wearers","volume":"40","author":"Barabino","year":"2005","journal-title":"Canadian Journal of Ophthalmology [Journal Canadien d'Ophtalmologie]"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0002|cit2","unstructured":"Dumbleton K Jones L Feng Y Keir N Woods CA Simpson TL The influence of a lubricant eye drop on contact lens discomfort in symptomatic hydrogel contact lens wearers (unpublished manuscript)"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0003|cit3","first-page":"ARVO E-abstract","article-title":"The influence of a guar-based lubricant eye drop on ocular discomfort in symptomatic hydrogel contact lens wearers","volume":"47","author":"Feng","year":"2006","journal-title":"Investigative Ophthalmology & Visual Science"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0004|cit4","unstructured":"Keir NJ Feng Y Dumbleton K Woods CA Jones L The influence of a lubricant eye drop on ocular discomfort in symptomatic hydrogel contact lens wearers American Academy of Optometry. Available at aaopt.org\/past-meeting-abstract-archives 2006 Program No. 20129"},{"issue":"1","key":"10.1002\/14651858.CD015751.pub2-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"38-43","DOI":"10.1097\/00140068-200301000-00010","article-title":"Preservative-free ocular hydrating agents in symptomatic contact lens wearers: saline versus PVP solution","volume":"29","author":"Malet","year":"2003","journal-title":"Eye & Contact Lens"},{"issue":"2","key":"10.1002\/14651858.CD015751.pub2-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"106-10","DOI":"10.1097\/ICL.0000000000000018","article-title":"Systane\u00ae Ultra lubricant eye drops for treatment of contact lens-related dryness","volume":"40","author":"McDonald","year":"2014","journal-title":"Eye & Contact Lens"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0007|cit7","unstructured":"An evaluation of a marketed lubricated eye drop in soft contact lens wearers who experience ocular dryness clinicaltrials.gov\/show\/NCT01132287"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0008|cit8","unstructured":"Formula identification (FID) 114657 in contact lens wearers clinicaltrials.gov\/show\/NCT02293538"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0009|cit9","unstructured":"Evaluation of systane complete for the treatment of contact lens discomfort clinicalTrials.gov\/show\/NCT03682809"},{"issue":"5","key":"10.1002\/14651858.CD015751.pub2-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"441-7","DOI":"10.1016\/j.clae.2019.10.141","article-title":"Evaluation of Systane\u00ae Complete for the treatment of contact lens discomfort","volume":"43","author":"Pucker","year":"2020","journal-title":"Contact Lens and Anterior Eye"},{"issue":"7","key":"10.1002\/14651858.CD015751.pub2-BIB0011|cit11","first-page":"1487","article-title":"Use of Systane\u00ae Complete over contact lenses to alleviate lens discomfort","volume":"61","author":"Brafford","year":"2020","journal-title":"Investigative Ophthalmology & Visual Science"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0012|cit12","unstructured":"Direct application of systane complete to contact lenses clinicaltrials.gov\/show\/NCT03848221"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0013|cit13","doi-asserted-by":"crossref","first-page":"101399","DOI":"10.1016\/j.clae.2020.12.004","article-title":"Application of Systane\u00ae Complete for the treatment of contact lens discomfort","volume":"44","author":"Pucker","year":"2021","journal-title":"Contact Lens and Anterior eye"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0014|cit14","unstructured":"The effect of Systane\u00ae Complete and Systane\u00ae Hydration on comfort, vision and satisfaction with mini-scleral contact lens wear trialsearch.who.int\/Trial2.aspx?TrialID=ACTRN12619000274178"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0015|cit15","unstructured":"Influences of viscosity of lubricating eye drops on orthokeratology treatment outcomes trialsearch.who.int\/Trial2.aspx?TrialID=ACTRN12619000773134"},{"issue":"2","key":"10.1002\/14651858.CD015751.pub2-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.joco.2016.03.007","article-title":"Objective and subjective assessing efficacy of a lubricating drop in eyes wearing silicone hydrogel contact lenses","volume":"28","author":"Asharlous","year":"2016","journal-title":"Journal of Current Ophthalmology"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0017|cit17","first-page":"785","volume-title":"Sullivan DA, Dartt DA, Meneray MA, editor(s). Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2. Advances in Experimental Medicine and Biology","volume":"438","author":"Berry","year":"1998"},{"issue":"3","key":"10.1002\/14651858.CD015751.pub2-BIB0018|cit18","first-page":"178-82","article-title":"Is there a better \"comfort drop\"?","volume":"61","author":"Caffery","year":"1990","journal-title":"Journal of the American Optometric Association"},{"issue":"5","key":"10.1002\/14651858.CD015751.pub2-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"538-44","DOI":"10.5301\/EJO.2011.6324","article-title":"Efficacy of 3 different artificial tears for the treatment of dry eye in frequent computer users and\/or contact lens users","volume":"21","author":"Calv\u00e3o-Santos","year":"2011","journal-title":"European Journal of Ophthalmology"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0020|cit20","first-page":"S307-11","article-title":"Comparison between viscous teardrops and saline solution to fill orthokeratology contact lenses before overnight wear","volume":"44 Suppl 1","author":"Carracedo","year":"2018","journal-title":"Eye & Contact Lens"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0021|cit21","unstructured":"A prospective, multicenter, randomized, open, parallel positive controlled clinical study to evaluate the efficacy and safety of multi-functional nursing solution for rigid gas permeable contact lens wearers trialsearch.who.int\/Trial2.aspx?TrialID=ChiCTR2200066298"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0022|cit22","unstructured":"Prospective, multicenter, randomized, parallel positive controlled clinical study to evaluate the efficacy and safety of rigid gas permeable contact lens lubrication for wearers of rigid breathable contact lenses trialsearch.who.int\/Trial2.aspx?TrialID=ChiCTR2300069668"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0023|cit23","unstructured":"A post market clinical follow up prospective study to evaluate safety and performance of eye drops with (herbal extract) (sodium hyaluronate) with euphrasia extract eye drops trialsearch.who.int\/Trial2.aspx?TrialID=CTRI\/2022\/07\/043793"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0024|cit24","unstructured":"The purpose of the study is to evaluate safety and performance of Eye Preparations - Sodium hyaluronate with Euphrasia extract eye drops trialsearch.who.int\/Trial2.aspx?TrialID=CTRI\/2022\/07\/043860"},{"issue":"8","key":"10.1002\/14651858.CD015751.pub2-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"3755-66","DOI":"10.1167\/iovs.18-24758","article-title":"Modulating contact lens discomfort with anti-inflammatory approaches: a randomized controlled trial","volume":"59","author":"Downie","year":"2018","journal-title":"Investigative ophthalmology & visual science"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0026|cit26","unstructured":"Dumbleton K Woods C Schneider S Fonn D Comparison of signs and symptoms of dry eye when using ocular lubricants of differing viscosity American Academy of Optometry. Available at aaopt.org\/past-meeting-abstract-archives 2008 Program No. 21174"},{"issue":"2","key":"10.1002\/14651858.CD015751.pub2-BIB0027|cit27","first-page":"114-9","article-title":"The effect of soft lens lubricants on symptoms and lens dehydration","volume":"17","author":"Efron","year":"1991","journal-title":"CLAO Journal"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.2147\/OPTH.S184776","article-title":"Safety and efficacy of lifitegrast 5% ophthalmic solution in contact lens discomfort","volume":"12","author":"Gonzalez","year":"2018","journal-title":"Clinical Ophthalmology"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"e43","DOI":"10.1016\/j.clae.2013.08.143","article-title":"Effect of lipid-based eyedrops on silicone hydrogel contact lens wear subjective acceptance","volume":"36","author":"Guillon","year":"2013","journal-title":"Contact Lens and Anterior Eye"},{"issue":"6","key":"10.1002\/14651858.CD015751.pub2-BIB0030|cit30","doi-asserted-by":"crossref","first-page":"373-7","DOI":"10.1097\/ICL.0000000000000138","article-title":"A comparative study between an oil-in-water emulsion and nonlipid eye drops used for rewetting contact lenses","volume":"41","author":"Guthrie","year":"2015","journal-title":"Eye & Contact Lens"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0031|cit31","unstructured":"Short-term evaluation of a commercial eyedrop in contact lens wearers trialsearch.who.int\/Trial2.aspx?TrialID=ISRCTN11194798"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0032|cit32","unstructured":"Evaluation of two different eye drops in symptomatic soft contact lens wearers trialsearch.who.int\/Trial2.aspx?TrialID=ISRCTN16230269"},{"issue":"4","key":"10.1002\/14651858.CD015751.pub2-BIB0033|cit33","first-page":"261-4","article-title":"Effect of sodium hyaluronate ophthalmic solution on peripheral staining of rigid contact lens wearers","volume":"21","author":"Itoi","year":"1995","journal-title":"CLAO Journal"},{"issue":"1","key":"10.1002\/14651858.CD015751.pub2-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"30-4","DOI":"10.1016\/j.clae.2020.02.013","article-title":"Comparison of the efficacy of eyelid warming masks and artificial tears for dry eye symptoms in contact lens wearers","volume":"44","author":"Jeon","year":"2021","journal-title":"Contact Lens & Anterior Eye"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0035|cit35","unstructured":"Changes in ocular surface after instillation of eye drops containing PVP jrct.niph.go.jp\/latest-detail\/jRCT1031230239"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0036|cit36","unstructured":"Effects of 3% diquafosol sodium ophthalmic solution on visual function in patient with dry eye wearing contact lens trialsearch.who.int\/Trial2.aspx?TrialID=JPRN-UMIN000010975"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0037|cit37","unstructured":"A randomized study comparing topical rebamipide with artificial tears in the treatment of dry eye with contact lens wearers trialsearch.who.int\/Trial2.aspx?TrialID=JPRN-UMIN000011397"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0038|cit38","unstructured":"Safety and efficacy of 3% diquafosol ophthalmic solution for soft contact lens-related dry eye trialsearch.who.int\/Trial2.aspx?TrialID=JPRN-UMIN000024064"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0039|cit39","unstructured":"Evaluation of sense of commercial eye drops for contact lens wearers trialsearch.who.int\/Trial2.aspx?TrialID=JPRN-UMIN000031169"},{"issue":"1","key":"10.1002\/14651858.CD015751.pub2-BIB0040|cit40","first-page":"27-32","article-title":"A two-week clinical evaluation of the safety of Systane\u00ae Ultra in contact lens-wearing patients","volume":"4","author":"Kading","year":"2010","journal-title":"Clinical Ophthalmology (Auckland, N.Z.)"},{"issue":"6","key":"10.1002\/14651858.CD015751.pub2-BIB0041|cit41","first-page":"499","article-title":"The influence of three lubricant eye drop on effects and ocular surface of myopia patients after orthokeratology lenses wearing","volume":"38","author":"Liu","year":"2020","journal-title":"Zhonghua Shiyan Yanke Zazhi\/Chinese Journal of Experimental Ophthalmology"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0042|cit42","unstructured":"Safety and efficacy of optive in contact lens wearers with dry eyes clinicaltrials.gov\/ct2\/show\/NCT00469573"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0043|cit43","unstructured":"Masked comparison of a new peg based artificial tear and optive for comfort, vision & wear time in patients wearing contact lenses clinicaltrials.gov\/show\/NCT00570843"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0044|cit44","unstructured":"Safety and acceptability of using a rewetting drop with contact lens wear clinicaltrials.gov\/show\/NCT00691197"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0045|cit45","unstructured":"Performance and acceptance of Optive\u00ae versus Hylocomod\u00ae eyedrops in patients with dry eye symptoms clinicaltrials.gov\/ct2\/show\/NCT00761202"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0046|cit46","unstructured":"Evaluation of the repeated usage of Systane\u00ae Ultra eyedrop clinicaltrials.gov\/show\/NCT01051804"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0047|cit47","unstructured":"A four week study of azithromycin ophthalmic solution, 1% versus rewetting drops in subjects with history and current complaint of contact lens-related dry eye (CLDE) clinicaltrials.gov\/ct2\/show\/NCT01105624"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0048|cit48","unstructured":"Study to evaluate a contact lens lubricating and rewetting drop clinicaltrials.gov\/show\/NCT01267656"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0049|cit49","unstructured":"Efficacy of the chronic application of tear formulations clinicaltrials.gov\/ct2\/show\/NCT01384851"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0050|cit50","unstructured":"Efficacy study of a new eyedrop on silicone hydrogel contact lens wearers with dry eye complaints clinicaltrials.gov\/ct2\/show\/NCT01543061"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0051|cit51","unstructured":"Assessment of safety and tolerability of chitosan-n-acetylcysteine eye drops in subjects while wearing contact lenses and before insertion of contact lenses clinicaltrials.gov\/show\/NCT01747616"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0052|cit52","unstructured":"A study to compare a new eye drop formulation with Refresh Contacts\u00ae clinicaltrials.gov\/show\/NCT01844388"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0053|cit53","unstructured":"The impact of hypo-osmolar drops on contact lens comfort (SAFFRON) clinicaltrials.gov\/ct2\/show\/NCT03050125"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0054|cit54","unstructured":"Prolongation of contact lens comfortable wear duration by CLM2 Topical Gel clinicaltrials.gov\/show\/NCT03994406"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0055|cit55","unstructured":"A safety and effectiveness study of a new preservative free rewetting drop classic.clinicaltrials.gov\/show\/NCT04175340"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0056|cit56","unstructured":"The effect of Xiidra on comfort and dryness in symptomatic contact lens wearers clinicaltrials.gov\/ct2\/show\/NCT04297618"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0057|cit57","unstructured":"Evaluation of comfort in symptomatic contact lens wearers clinicaltrials.gov\/ct2\/show\/NCT04963543"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0058|cit58","unstructured":"Efficacy of \"Aquoral Lipo\" artificial tears in contact lens wearers with discomfort clinicaltrials.gov\/show\/NCT05290727"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0059|cit59","unstructured":"Lifitegrast 5% for the treatment of dry eye in habitual soft contact lens wearers clinicaltrials.gov\/ct2\/show\/NCT05505292"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0060|cit60","unstructured":"Evaluation of comfort of ocular lubricants in symptomatic contact lens wearers clinicaltrials.gov\/show\/NCT05741216"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0061|cit61","unstructured":"Clinical investigation of visual acuity in contact lens wearers after instillation of investigational lubricating eye drops clinicaltrials.gov\/show\/NCT05814367"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0062|cit62","unstructured":"Systane\u00ae Ultra preservative free lubricant eye drops classic.clinicaltrials.gov\/show\/NCT05902364"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0063|cit63","unstructured":"Systane\u00ae Complete preservative free lubricant eye drops classic.clinicaltrials.gov\/show\/NCT05932225"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0064|cit64","unstructured":"Clinical investigation of visual acuity in contact lens wearers after instillation of a lipid-based lubricating eye drop classic.clinicaltrials.gov\/show\/NCT06131476"},{"issue":"8","key":"10.1002\/14651858.CD015751.pub2-BIB0065|cit65","doi-asserted-by":"crossref","first-page":"979-86","DOI":"10.1097\/OPX.0000000000000878","article-title":"Dual-polymer drops, contact lens comfort, and lid wiper epitheliopathy","volume":"93","author":"Nichols","year":"2016","journal-title":"Optometry and Vision Science"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0066|cit66","doi-asserted-by":"crossref","first-page":"e33","DOI":"10.1016\/j.clae.2014.11.050","article-title":"Clinical evaluation of a dual-polymer rewetting drop: improved patient-reported outcomes and lid wiper epitheliopathy in contact lens wearers","volume":"38","author":"Simmons","year":"2015","journal-title":"Contact Lens & Anterior Eye"},{"issue":"11","key":"10.1002\/14651858.CD015751.pub2-BIB0067|cit67","doi-asserted-by":"crossref","first-page":"5534","DOI":"10.1007\/s12325-021-01910-8","article-title":"The effect of diquafosol ophthalmic solution on clinical parameters and visual function in soft contact lens-related dry eye","volume":"38","author":"Ogami","year":"2021","journal-title":"Advanced Therapy"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0068|cit68","first-page":"ARVO E-abstract","article-title":"Lubricants and their effect on comfort with silicone hydrogel and conventional hydrogel lens wear","volume":"45","author":"Ozkan","year":"2004","journal-title":"Investigative Ophthalmology & Visual Science"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0069|cit69","unstructured":"Ozkan J Papas E Effect of dry eye lubricant drops on symptomatic silicone hydrogel wearers American Academy of Optometry. Available at aaopt.org\/past-meeting-abstract-archives 2005 Program No. 19162"},{"issue":"10","key":"10.1002\/14651858.CD015751.pub2-BIB0070|cit70","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1097\/OPX.0000000000000947","article-title":"Effects of lipid supplements on tear biochemistry in contact lens wearers","volume":"93","author":"Rohit","year":"2016","journal-title":"Optometry and Vision Science"},{"issue":"2","key":"10.1002\/14651858.CD015751.pub2-BIB0071|cit71","doi-asserted-by":"crossref","first-page":"174-82","DOI":"10.1097\/OPX.0000000000000996","article-title":"Lipid supplements and clinical aspects of tear film in habitual lens wearers","volume":"94","author":"Rohit","year":"2017","journal-title":"Optometry and Vision Science"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0072|cit72","unstructured":"Sasai A Vehige J Simmons P Beard B Lai F Clinical evaluation of an artificial tear in contact lens wearers American Academy of Optometry. Available at aaopt.org\/past-meeting-abstract-archives 2009 Program No. 21747"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0073|cit73","doi-asserted-by":"crossref","first-page":"75","DOI":"10.2147\/OPTO.S249078","article-title":"Effects of aqueous-supplementing artificial tears in wearers of biweekly replacement contact lenses vs wearers of daily disposable contact lenses","volume":"12","author":"Tavazzi","year":"2020","journal-title":"Clinical Optometry (Auckland)"},{"issue":"12","key":"10.1002\/14651858.CD015751.pub2-BIB0074|cit74","doi-asserted-by":"publisher","first-page":"2545-51","DOI":"10.4314\/tjpr.v22i12.18","article-title":"Effect of sodium hyaluronate eye drop on tear film stability and tear secretion in patients with rigid gas-permeable contact lens-associated xerophthalmia","volume":"22","author":"Xu","year":"2023","journal-title":"Tropical Journal of Pharmaceutical Research"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0075|cit75","unstructured":"The effect of tear supplements on contact lens comfort clinicaltrials.gov\/show\/NCT02956083"},{"issue":"4","key":"10.1002\/14651858.CD015751.pub2-BIB0076|cit76","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.preteyeres.2010.03.001","article-title":"Preservatives in eyedrops: the good, the bad and the ugly","volume":"29","author":"Baudouin","year":"2010","journal-title":"Progress in Retinal and Eye Research"},{"issue":"6","key":"10.1002\/14651858.CD015751.pub2-BIB0077|cit77","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1097\/00003226-200108000-00011","article-title":"Characterization of ocular surface symptoms from optometric practices in North America","volume":"20","author":"Begley","year":"2001","journal-title":"Cornea"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0078|cit78","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1097\/00006324-198912000-00006","article-title":"Symptomatology of HEMA contact lens wear","volume":"66","author":"Brennan","year":"1989","journal-title":"Optometry and Vision Science"},{"issue":"1","key":"10.1002\/14651858.CD015751.pub2-BIB0079|cit79","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.clae.2005.12.004","article-title":"Dryness symptoms among an unselected clinical population with and without contact lens wear","volume":"29","author":"Chalmers","year":"2006","journal-title":"Contact Lens and Anterior Eye"},{"issue":"10","key":"10.1002\/14651858.CD015751.pub2-BIB0080|cit80","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1097\/OPX.0b013e318269c90d","article-title":"Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) and opinion of contact lens performance","volume":"89","author":"Chalmers","year":"2012","journal-title":"Optometry and Vision Science"},{"issue":"5","key":"10.1002\/14651858.CD015751.pub2-BIB0081|cit81","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.clae.2016.04.005","article-title":"Cutoff score and responsiveness of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) in a large daily disposable contact lens registry","volume":"39","author":"Chalmers","year":"2016","journal-title":"Contact Lens and Anterior Eye"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0082|cit82","volume-title":"Statistical power analysis in the behavioral sciences","author":"Cohen","year":"1988"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0083|cit83","unstructured":"Covidence Veritas Health Innovation"},{"issue":"11","key":"10.1002\/14651858.CD015751.pub2-BIB0084|cit84","doi-asserted-by":"crossref","first-page":"TFOS123","DOI":"10.1167\/iovs.13-13235","article-title":"The TFOS International Workshop on Contact Lens Discomfort: report of the contact lens interactions with the tear film subcommittee","volume":"54","author":"Craig","year":"2013","journal-title":"Investigative Ophthalmology and Visual Science"},{"issue":"4","key":"10.1002\/14651858.CD015751.pub2-BIB0085|cit85","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.jtos.2017.08.003","article-title":"TFOS DEWS II Report Executive Summary","volume":"15","author":"Craig","year":"2017","journal-title":"Ocular Surface"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0086|cit86","unstructured":"Deeks JJ Higgins JP Altman DG Chapter 10: Analysing data and undertaking meta-analyses. In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 6.3 (updated February 2022). Cochrane, 2022 Available from training.cochrane.org\/handbook\/archive\/v6.3"},{"issue":"3","key":"10.1002\/14651858.CD015751.pub2-BIB0087|cit87","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1517\/14656566.2010.518612","article-title":"Pharmacotherapy of dry eye","volume":"12","author":"Dogru","year":"2011","journal-title":"Expert Opinion on Pharmacotherapy"},{"issue":"8","key":"10.1002\/14651858.CD015751.pub2-BIB0088|cit88","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1097\/00006324-199708000-00023","article-title":"A patient questionnaire approach to estimating the prevalence of dry eye symptoms in patients presenting to optometric practices across Canada","volume":"74","author":"Doughty","year":"1997","journal-title":"Optometry and Vision Science"},{"issue":"11","key":"10.1002\/14651858.CD015751.pub2-BIB0089|cit89","doi-asserted-by":"crossref","first-page":"TFOS20","DOI":"10.1167\/iovs.13-13125","article-title":"The TFOS International Workshop on Contact Lens Discomfort: report of the subcommittee on epidemiology","volume":"54","author":"Dumbleton","year":"2013","journal-title":"Investigative Ophthalmology and Visual Science"},{"issue":"11","key":"10.1002\/14651858.CD015751.pub2-BIB0090|cit90","doi-asserted-by":"crossref","first-page":"TFOS98","DOI":"10.1167\/iovs.13-13187","article-title":"The TFOS International Workshop on Contact Lens Discomfort: report of the contact lens interactions with the ocular surface and adnexa subcommittee","volume":"54","author":"Efron","year":"2013","journal-title":"Investigative Ophthalmology and Visual Science"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0091|cit91","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.preteyeres.2016.04.004","article-title":"Lid wiper epitheliopathy","volume":"53","author":"Efron","year":"2016","journal-title":"Progress in Retinal and Eye Research"},{"issue":"7109","key":"10.1002\/14651858.CD015751.pub2-BIB0092|cit92","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"issue":"3","key":"10.1002\/14651858.CD015751.pub2-BIB0093|cit93","doi-asserted-by":"crossref","first-page":"101544","DOI":"10.1016\/j.clae.2021.101544","article-title":"Improving ocular surface comfort in contact lens wearers","volume":"45","author":"Fern\u00e1ndez-Jimenez","year":"2022","journal-title":"Contact Lens and Anterior Eye"},{"issue":"1","key":"10.1002\/14651858.CD015751.pub2-BIB0094|cit94","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.jtos.2018.10.004","article-title":"Tear film inflammatory cytokine upregulation in contact lens discomfort","volume":"17","author":"Gad","year":"2019","journal-title":"Ocular Surface"},{"issue":"2","key":"10.1002\/14651858.CD015751.pub2-BIB0095|cit95","first-page":"130","article-title":"How to identify randomized controlled trials in MEDLINE: ten years on","volume":"94","author":"Glanville","year":"2006","journal-title":"Journal of the Medical Library Association"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0096|cit96","unstructured":"Higgins JP Li T Deeks JJ Chapter 6: Choosing effect measures and computing estimates of effect. In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 6.3 (updated February 2022). Cochrane, 2022 Available from www.training.cochrane.org\/handbook\/archive\/v6.3"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0097|cit97","unstructured":"Higgins JP Eldridge S Li T Chapter 23: Including variants on randomized trials. In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 6.4 (updated August 2023). Cochrane, 2023 Available from www.training.cochrane.org\/handbook"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0098|cit98","unstructured":"Higgins JP Savovi\u0107 J Page MJ Elbers RG Sterne JA Chapter 8: Assessing risk of bias in a randomized trial. In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 6.4 (updated August 2023). Cochrane, 2023 Available from training.cochrane.org\/handbook"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0099|cit99","unstructured":"Hu J Kong L Zhu S Ju M Zhang Q Efficacy and safety of manuka honey for dry eye Clinical and Experimental Optometry 1 11 10.1080\/08164622.2022.2106779"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0100|cit100","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.jtos.2023.04.010","article-title":"TFOS Lifestyle: impact of contact lenses on the ocular surface","volume":"29","author":"Jones","year":"2023","journal-title":"Ocular Surface"},{"issue":"6","key":"10.1002\/14651858.CD015751.pub2-BIB0101|cit101","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1097\/APO.0000000000000329","article-title":"Contact lens wear and dry eye: beyond the known","volume":"9","author":"Koh","year":"2020","journal-title":"Asia-Pacific Journal of Ophthalmology"},{"issue":"7","key":"10.1002\/14651858.CD015751.pub2-BIB0102|cit102","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1167\/tvst.11.7.16","article-title":"Ocular surface immune cell profiles in contact lens-induced discomfort","volume":"11","author":"Nair","year":"2022","journal-title":"Translational Vision Science and Technology"},{"issue":"4","key":"10.1002\/14651858.CD015751.pub2-BIB0103|cit103","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1167\/iovs.05-1392","article-title":"Tear film, contact lens, and patient-related factors associated with contact lens-related dry eye","volume":"47","author":"Nichols","year":"2006","journal-title":"Investigative Ophthalmology and Visual Science"},{"issue":"11","key":"10.1002\/14651858.CD015751.pub2-BIB0104|cit104","first-page":"TFOS7\u201313","article-title":"The TFOS International Workshop on Contact Lens Discomfort: executive summary","volume":"54","author":"Nichols","year":"2013","journal-title":"Investigative Ophthalmology and Visual Science"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0105|cit105","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0106|cit106","unstructured":"Page MJ Higgins JP Sterne JA Chapter 13: Assessing risk of bias due to missing results in a synthesis. In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 6.4 (updated August 2023). Cochrane, 2023 Available from training.cochrane.org\/handbook"},{"issue":"7","key":"10.1002\/14651858.CD015751.pub2-BIB0107|cit107","doi-asserted-by":"crossref","first-page":"4390","DOI":"10.1167\/iovs.10-7051","article-title":"Estimating a just-noticeable difference for ocular comfort in contact lens wearers","volume":"52","author":"Papas","year":"2011","journal-title":"Investigative Ophthalmology and Visual Science"},{"issue":"11","key":"10.1002\/14651858.CD015751.pub2-BIB0108|cit108","doi-asserted-by":"crossref","first-page":"TFOS183","DOI":"10.1167\/iovs.13-13166","article-title":"The TFOS International Workshop on Contact Lens Discomfort: report of the management and therapy subcommittee","volume":"54","author":"Papas","year":"2013","journal-title":"Investigative Ophthalmology and Visual Science"},{"issue":"2","key":"10.1002\/14651858.CD015751.pub2-BIB0109|cit109","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1177\/204946370800100203","article-title":"Cultural Influences on Pain","volume":"1","author":"Peacock","year":"2008","journal-title":"Reviews in Pain"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0110|cit110","doi-asserted-by":"crossref","first-page":"85","DOI":"10.2147\/OPTO.S198637","article-title":"A review of contact lens dropout","volume":"12","author":"Pucker","year":"2020","journal-title":"Clinical Optometry"},{"issue":"5","key":"10.1002\/14651858.CD015751.pub2-BIB0111|cit111","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.clae.2020.04.013","article-title":"A review of the compatibility of topical artificial tears and rewetting drops with contact lenses","volume":"43","author":"Pucker","year":"2020","journal-title":"Contact Lens and Anterior Eye"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0112|cit112","unstructured":"Review Manager (RevMan) The Cochrane Collaboration 2023"},{"issue":"1","key":"10.1002\/14651858.CD015751.pub2-BIB0113|cit113","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S1367-0484(97)80030-6","article-title":"Therapeutic contact lenses and eyedrops \u2014 is there a problem?","volume":"20","author":"Rubinstein","year":"1997","journal-title":"Contact Lens and Anterior Eye"},{"issue":"5","key":"10.1002\/14651858.CD015751.pub2-BIB0114|cit114","doi-asserted-by":"crossref","first-page":"101560","DOI":"10.1016\/j.clae.2021.101560","article-title":"A review of meibomian gland structure, function, and contact lens wear","volume":"45","author":"Rueff","year":"2021","journal-title":"Contact Lens and Anterior Eye"},{"issue":"10","key":"10.1002\/14651858.CD015751.pub2-BIB0115|cit115","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1001\/jamaophthalmol.2018.3352","article-title":"Research questions and outcomes prioritized by patients with dry eye","volume":"136","author":"Saldanha","year":"2018","journal-title":"JAMA Ophthalmology"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0116|cit116","unstructured":"Sch\u00fcnemann HJ Higgins JP Vist GE Glasziou P Akl EA Skoetz N Guyatt GH Chapter 14: Completing 'Summary of findings' tables and grading the certainty of the evidence. In: Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 6.4 (updated August 2023). Cochrane, 2023 Available from training.cochrane.org\/handbook"},{"issue":"1","key":"10.1002\/14651858.CD015751.pub2-BIB0117|cit117","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.clae.2017.09.011","article-title":"Exploring the links between contact lens comfort, osmolarity and lid wiper staining","volume":"41","author":"Stahl","year":"2018","journal-title":"Contact Lens and Anterior Eye"},{"issue":"3","key":"10.1002\/14651858.CD015751.pub2-BIB0118|cit118","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.jtos.2017.05.003","article-title":"TFOS DEWS II Epidemiology Report","volume":"15","author":"Stapleton","year":"2017","journal-title":"Ocular Surface"},{"issue":"2","key":"10.1002\/14651858.CD015751.pub2-BIB0119|cit119","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.clae.2021.02.010","article-title":"CLEAR - Contact lens complications","volume":"44","author":"Stapleton","year":"2021","journal-title":"Contact Lens and Anterior Eye"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0120|cit120","doi-asserted-by":"crossref","first-page":"l4898","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"BMJ"},{"issue":"11","key":"10.1002\/14651858.CD015751.pub2-BIB0121|cit121","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1016\/j.ophtha.2008.06.022","article-title":"Prevalence of dry eye disease among Japanese visual display terminal users","volume":"115","author":"Uchino","year":"2008","journal-title":"Ophthalmology"},{"issue":"6","key":"10.1002\/14651858.CD015751.pub2-BIB0122|cit122","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.ajo.2008.06.030","article-title":"Japan Ministry of Health Study on prevalence of dry eye disease among Japanese high school students","volume":"146","author":"Uchino","year":"2008","journal-title":"American Journal of Ophthalmology"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0123|cit123","unstructured":"Contact Lens Care Products \u2013 Premarket Notification 510(k) Guidance www.fda.gov\/medical-devices\/guidance-documents-medical-devices-and-radiation-emitting-products\/contact-lens-care-products-premarket-notification-510k-guidance"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0124|cit124","unstructured":"Department of Health and Human Services (DHHS) Part 349 - Ophthalmic drug products for over-the-counter human use www.govinfo.gov\/content\/pkg\/CFR-2021-title21-vol5\/pdf\/CFR-2021-title21-vol5-part349.pdf"},{"issue":"10","key":"10.1002\/14651858.CD015751.pub2-BIB0125|cit125","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1097\/00006324-199910000-00022","article-title":"The frequency of ocular symptoms during spectacle and daily soft and rigid contact lens wear","volume":"76","author":"Vajdic","year":"1999","journal-title":"Optometry and Vision Science"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0126|cit126","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.2147\/OPTH.S211611","article-title":"The use of preservatives in dry eye drops","volume":"13","author":"Walsh","year":"2019","journal-title":"Clinical Ophthalmology"},{"key":"10.1002\/14651858.CD015751.pub2-BIB0127|cit127","unstructured":"WebPlotDigitizer Rohatgi A"},{"issue":"6","key":"10.1002\/14651858.CD015751.pub2-BIB0128|cit128","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1046\/j.1475-1313.2002.00066.x","article-title":"A multi-centre study of lapsed contact lens wearers","volume":"22","author":"Young","year":"2002","journal-title":"Ophthalmic and Physiological Optics"},{"issue":"2","key":"10.1002\/14651858.CD015751.pub2-BIB0129|cit129","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.clae.2010.08.005","article-title":"Characterizing contact lens-related dryness symptoms in a cross-section of UK soft lens wearers","volume":"34","author":"Young","year":"2011","journal-title":"Contact Lens and Anterior Eye"},{"issue":"4","key":"10.1002\/14651858.CD015751.pub2-BIB0130|cit130","doi-asserted-by":"crossref","first-page":"226","DOI":"10.3109\/09286586.2012.670742","article-title":"Prevalence and risk factors associated with dry eye syndrome among senior high school students in a county of Shandong province, China","volume":"19","author":"Zhang","year":"2012","journal-title":"Ophthalmic Epidemiology"},{"issue":"11","key":"10.1002\/14651858.CD015751.pub2-BIB0131|cit131","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD015751","article-title":"Lubricating drops for contact lens discomfort in adults","author":"Caffery","year":"2023","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","deposited":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T13:19:38Z","timestamp":1764940778000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD015751.pub2"}},"subtitle":[],"editor":[{"name":"Cochrane Eyes and Vision Group","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,9,5]]},"references-count":131,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2024,9]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd015751.pub2","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,5]]}}}