{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T20:38:43Z","timestamp":1765399123735,"version":"3.46.0"},"reference-count":72,"publisher":"Wiley","issue":"12","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.cd016277","type":"journal-article","created":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T20:35:36Z","timestamp":1765398936000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evan's blue dye test for detection of aspiration in tracheostomized patients"],"prefix":"10.1002","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2486-130X","authenticated-orcid":false,"given":"Diego","family":"Ivaldi","sequence":"additional","affiliation":[{"name":"Cochrane Associate Centre; Universidad Hospital Italiano de Buenos Aires; Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana Andrea","family":"Burgos","sequence":"additional","affiliation":[{"name":"Cochrane Associate Centre; Universidad Hospital Italiano de Buenos Aires; Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Rico","sequence":"additional","affiliation":[{"name":"Kinesiology Service; Cl\u00ednica Santa Catalina; Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia B","family":"Varela","sequence":"additional","affiliation":[{"name":"Cochrane Associate Centre; Universidad Hospital Italiano de Buenos Aires; Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samanta","family":"D\u00edaz Menai","sequence":"additional","affiliation":[{"name":"Cochrane Associate Centre; Universidad Hospital Italiano de Buenos Aires; Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila Micaela","family":"Escobar Liquitay","sequence":"additional","affiliation":[{"name":"Cochrane Associate Centre; Universidad Hospital Italiano de Buenos Aires; Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis I","family":"Garegnani","sequence":"additional","affiliation":[{"name":"Cochrane Associate Centre; Universidad Hospital Italiano de Buenos Aires; Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,10]]},"reference":[{"key":"10.1002\/14651858.CD016277-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"895\u2013919","DOI":"10.4187\/respcare.02971","article-title":"Tracheostomy: epidemiology, indications, timing, technique, and outcomes","volume":"59","author":"Cheung","year":"2014","journal-title":"Respiratory Care"},{"key":"10.1002\/14651858.CD016277-BIB0002|cit2","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.ccc.2016.12.007","article-title":"Tracheostomy update: when and how","volume":"33","author":"Freeman","year":"2017","journal-title":"Critical Care Clinics"},{"key":"10.1002\/14651858.CD016277-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"744\u20137","DOI":"10.1288\/00005537-198907000-00016","article-title":"Voice intensity of patients using a Communi-Trach I cuffed speaking tracheostomy tube","volume":"99","author":"Leder","year":"1989","journal-title":"Laryngoscope"},{"key":"10.1002\/14651858.CD016277-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"199\u2013204","DOI":"10.1177\/0003489416683192","article-title":"Influence of external subglottic air flow on dysphagic tracheotomized patients with severe brain injury","volume":"126","author":"Kothari","year":"2017","journal-title":"Annals of Otology, Rhinology & Laryngology"},{"key":"10.1002\/14651858.CD016277-BIB0005|cit5","first-page":"542\u20139","article-title":"Late complications of tracheostomy","volume":"50","author":"Epstein","year":"2005","journal-title":"Respiratory Care"},{"key":"10.1002\/14651858.CD016277-BIB0006|cit6","first-page":"1076\u201381","article-title":"Tracheostomy decannulation","volume":"55","author":"O\u2019Connor","year":"2010","journal-title":"Respiratory Care"},{"key":"10.1002\/14651858.CD016277-BIB0007|cit7","first-page":"900\u20139","article-title":"Ventilator-associated pneumonia: issues related to the artificial airway","volume":"50","author":"Diaz","year":"2005","journal-title":"Respiratory Care"},{"key":"10.1002\/14651858.CD016277-BIB0008|cit8","volume-title":"StatPearls","author":"Sanivarapu","year":"2024"},{"key":"10.1002\/14651858.CD016277-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"2184\u201393","DOI":"10.1097\/01.CCM.0000181731.53912.D9","article-title":"Clinical and economic consequences of ventilator-associated pneumonia: a systematic review","volume":"33","author":"Safdar","year":"2005","journal-title":"Critical Care Medicine"},{"key":"10.1002\/14651858.CD016277-BIB0010|cit10","first-page":"1\u201312","article-title":"The practice of tracheostomy decannulation\u2014a systematic review","volume":"5","author":"Singh","year":"2017","journal-title":"Journal of Intensive Care Medicine"},{"key":"10.1002\/14651858.CD016277-BIB0011|cit11","first-page":"538\u201341","article-title":"Tracheostomy decannulation","volume":"50","author":"Christopher","year":"2005","journal-title":"Respiratory Care"},{"key":"10.1002\/14651858.CD016277-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s40560-022-00626-3","article-title":"Tracheostomy decannulation protocol in patients with prolonged tracheostomy referred to a rehabilitation hospital: a prospective cohort study","volume":"10","author":"Zhou","year":"2022","journal-title":"Journal of Intensive Care Medicine"},{"key":"10.1002\/14651858.CD016277-BIB0013|cit13","doi-asserted-by":"crossref","first-page":"1\u20139","DOI":"10.1186\/cc6802","article-title":"Determinants of tracheostomy decannulation: an international survey","volume":"12","author":"Stelfox","year":"2008","journal-title":"Critical Care"},{"key":"10.1002\/14651858.CD016277-BIB0014|cit14","first-page":"1626\u201334","article-title":"The ventilator liberation process: update on technique, timing, and termination of tracheostomy","volume":"Care 57","author":"Bittner","year":"2012","journal-title":"Respiratory Care"},{"key":"10.1002\/14651858.CD016277-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"665\u201373","DOI":"10.1378\/chest.09-1823","article-title":"The incidence of dysphagia following endotracheal intubation: a systematic review","volume":"137","author":"Skoretz","year":"2010","journal-title":"Chest Journal"},{"key":"10.1002\/14651858.CD016277-BIB0016|cit16","doi-asserted-by":"crossref","first-page":"e141\u201351","DOI":"10.1097\/CCM.0000000000004098","article-title":"Investigating swallowing and tracheostomy following critical illness: a scoping review","volume":"48","author":"Skoretz","year":"2020","journal-title":"Critical Care Medicine"},{"key":"10.1002\/14651858.CD016277-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"116\u201322","DOI":"10.1044\/sasd23.3.116","article-title":"Tracheostomy and dysphagia: true, true, and unrelated?","volume":"23","author":"Francis","year":"2014","journal-title":"Perspectives on Swallowing and Swallowing Disorders (Dysphagia)"},{"key":"10.1002\/14651858.CD016277-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"586\u201390","DOI":"10.1177\/000348948909800803","article-title":"Bedside videolaryngoscopic assessment of intubation trauma","volume":"98","author":"Alessi","year":"1989","journal-title":"Annals of Otology, Rhinology & Laryngology"},{"key":"10.1002\/14651858.CD016277-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"65\u201376","DOI":"10.1016\/0002-9343(81)90413-7","article-title":"Complications and consequences of endotracheal intubation and tracheotomy. A prospective study of 150 critically ill adult patients","volume":"70","author":"Stauffer","year":"1981","journal-title":"American Journal of Medicine"},{"key":"10.1002\/14651858.CD016277-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"1278\u201382","DOI":"10.1378\/chest.09-2792","article-title":"Swallowing dysfunction in nonneurologic critically ill patients who require percutaneous dilatational tracheostomy","volume":"137","author":"Romero","year":"2010","journal-title":"Chest Journal"},{"key":"10.1002\/14651858.CD016277-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"167\u201372","DOI":"10.1378\/chest.109.1.167","article-title":"Swallowing dysfunction in patients receiving prolonged mechanical ventilation","volume":"109","author":"Tolep","year":"1996","journal-title":"Chest Journal"},{"key":"10.1002\/14651858.CD016277-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"1357\u201360","DOI":"10.1016\/0016-5085(95)90682-7","article-title":"Deglutitive aspiration in patients with tracheostomy: effect of tracheostomy on the duration of vocal cord closure","volume":"108","author":"Shaker","year":"1995","journal-title":"Gastroenterology"},{"key":"10.1002\/14651858.CD016277-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"e9\u201313","DOI":"10.1016\/j.jcrc.2010.05.036","article-title":"Swallowing dysfunction after mechanical ventilation in trauma patients","volume":"26","author":"Brown","year":"2011","journal-title":"Journal of Critical Care"},{"issue":"8","key":"10.1002\/14651858.CD016277-BIB0024|cit24","doi-asserted-by":"crossref","first-page":"784\u201389","DOI":"10.1001\/archoto.2010.129","article-title":"Consequence of dysphagia in the hospitalized patient: impact on prognosis and hospital resources","volume":"136","author":"Altman","year":"2010","journal-title":"Archives of Otolaryngology - Head and Neck surgery"},{"key":"10.1002\/14651858.CD016277-BIB0025|cit25","first-page":"140\u201364","article-title":"Dysphagia: evaluation and treatment","volume":"47","author":"Logemann","year":"2009","journal-title":"Folia Phoniatrica et Logopaedica"},{"issue":"2","key":"10.1002\/14651858.CD016277-BIB0026|cit26","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/BF00417897","article-title":"A penetration-aspiration scale","volume":"11","author":"Rosenbek","year":"1996","journal-title":"Dysphagia"},{"key":"10.1002\/14651858.CD016277-BIB0027|cit27","first-page":"560\u20139","article-title":"Aspiration of oral feedings in patients with tracheostomies","volume":"7","author":"Pannunzio","year":"1996","journal-title":"AACN Advanced Critical Care"},{"key":"10.1002\/14651858.CD016277-BIB0028|cit28","volume-title":"Respiratory Disease Series: Diagnostic Tools and Disease Managements","author":"Komiya","year":"2020"},{"key":"10.1002\/14651858.CD016277-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"1493\u20131500","DOI":"10.1007\/s00455-022-10412-w","article-title":"Mortality from aspiration pneumonia: incidence, trends, and risk factors","volume":"37","author":"Gupte","year":"2022","journal-title":"Dysphagia"},{"key":"10.1002\/14651858.CD016277-BIB0030|cit30","first-page":"68\u201370","article-title":"Aspiration in patients with tracheostomies","volume":"136","author":"Cameron","year":"1973","journal-title":"Surgery, Gynecology & Obstetrics"},{"key":"10.1002\/14651858.CD016277-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"172\u201374","DOI":"10.1007\/BF00260973","article-title":"The modified Evan\u2019s blue dye procedure fails to detect aspiration in the tracheostomized patient: five case reports","volume":"10","author":"Thompson-Henry","year":"1995","journal-title":"Dysphagia"},{"key":"10.1002\/14651858.CD016277-BIB0032|cit32","doi-asserted-by":"crossref","first-page":"1969\u201372","DOI":"10.1097\/00005537-200311000-00021","article-title":"The accuracy of the modified Evan\u2019s blue dye test in predicting aspiration","volume":"113","author":"Belafsky","year":"2003","journal-title":"Laryngoscope"},{"key":"10.1002\/14651858.CD016277-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"441\u20135","DOI":"10.1053\/j.jvca.2016.07.031","article-title":"A new modified Evans blue dye test as screening test for aspiration in tracheostomized patients","volume":"31","author":"Fiorelli","year":"2017","journal-title":"Journal of Cardiothoracic and Vascular Anesthesia"},{"key":"10.1002\/14651858.CD016277-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1044\/sasd11.4.4","article-title":"Blue dye in the evaluation of dysphagia","volume":"11","author":"Swigert","year":"2002","journal-title":"Perspectives on Swallowing and Swallowing Disorders (Dysphagia)"},{"key":"10.1002\/14651858.CD016277-BIB0035|cit35","doi-asserted-by":"crossref","first-page":"1255\u201363","DOI":"10.4187\/respcare.05470","article-title":"Clinical criteria for tracheostomy decannulation in subjects with acquired brain injury","volume":"62","author":"Enrichi","year":"2017","journal-title":"Respiratory Care"},{"key":"10.1002\/14651858.CD016277-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"1162\u201370","DOI":"10.1080\/09638288.2016.1189607","article-title":"Implementation of a respiratory rehabilitation protocol: weaning from the ventilator and tracheostomy in difficult-to-wean patients with spinal cord injury","volume":"39","author":"Gundogdu","year":"2017","journal-title":"Disability and Rehabilitation"},{"key":"10.1002\/14651858.CD016277-BIB0037|cit37","doi-asserted-by":"crossref","first-page":"601\u201305","DOI":"10.1038\/sc.2016.194","article-title":"Successful tracheostomy decannulation after complete or sensory incomplete cervical spinal cord injury","volume":"55","author":"Kim","year":"2017","journal-title":"Spinal Cord"},{"key":"10.1002\/14651858.CD016277-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s40248-015-0032-1","article-title":"Weaning from tracheostomy in subjects undergoing pulmonary rehabilitation","volume":"10","author":"Pasqua","year":"2015","journal-title":"Multidisciplinary Respiratory Medicine"},{"key":"10.1002\/14651858.CD016277-BIB0039|cit39","first-page":"187\u201394","article-title":"Decannulation following tracheostomy for prolonged mechanical ventilation","volume":"24","author":"O\u2019Connor","year":"2009","journal-title":"Journal of Intensive Care Medicine"},{"key":"10.1002\/14651858.CD016277-BIB0040|cit40","doi-asserted-by":"crossref","first-page":"935\u201347","DOI":"10.1007\/s00455-020-10115-0","article-title":"A systematic review of tracheostomy modifications and swallowing in adults","volume":"35","author":"Skoretz","year":"2020","journal-title":"Dysphagia"},{"issue":"12","key":"10.1002\/14651858.CD016277-BIB0041|cit41","first-page":"1658","article-title":"A North American survey of respiratory therapist and physician tracheostomy decannulation practices","volume":"54","author":"Stelfox","year":"2009","journal-title":"Respiratory Care"},{"key":"10.1002\/14651858.CD016277-BIB0042|cit42","doi-asserted-by":"crossref","first-page":"462\u201372","DOI":"10.1007\/s00455-016-9700-3","article-title":"Parameters of instrumental swallowing evaluations: describing a diagnostic dilemma","volume":"31","author":"Pisegna","year":"2016","journal-title":"Dysphagia"},{"key":"10.1002\/14651858.CD016277-BIB0043|cit43","first-page":"32\u20138","article-title":"Simultaneous modified barium swallow and blue dye tests: a determination of the accuracy of blue dye test aspiration findings","volume":"18","author":"O\u2019Neil-Pirozzi","year":"2003","journal-title":"Dysphagia"},{"issue":"1","key":"10.1002\/14651858.CD016277-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/hed.2880160105","article-title":"Scintigraphic assessment of aspiration in head and neck cancer patients with tracheostomy","volume":"16","author":"Muz","year":"1994","journal-title":"Head & Neck"},{"issue":"3","key":"10.1002\/14651858.CD016277-BIB0045|cit45","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.oraloncology.2010.11.020","article-title":"The clinical application of the 100mL water swallow test in head and neck cancer","volume":"47","author":"Patterson","year":"2011","journal-title":"Oral Oncology"},{"key":"10.1002\/14651858.CD016277-BIB0046|cit46","doi-asserted-by":"crossref","first-page":"1328\u201330","DOI":"10.1097\/00003246-199012000-00004","article-title":"Swallowing disorders in patients with prolonged orotracheal intubation or tracheostomy tubes","volume":"18","author":"DeVita","year":"1990","journal-title":"Critical Care Medicine"},{"key":"10.1002\/14651858.CD016277-BIB0047|cit47","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fneur.2023.1099307","article-title":"Predictors of long-term decannulation in patients with disorders of consciousness","volume":"14","author":"Chen","year":"2023","journal-title":"Frontiers in Neurology"},{"key":"10.1002\/14651858.CD016277-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"552\u201372","DOI":"10.1007\/s00455-023-10646-2","article-title":"Predictive factors for successful decannulation in patients with tracheostomies and brain injuries: a systematic review","volume":"39","author":"Gallice","year":"2024","journal-title":"Dysphagia"},{"key":"10.1002\/14651858.CD016277-BIB0049|cit49","doi-asserted-by":"crossref","first-page":"749\u201353","DOI":"10.1016\/j.rmed.2010.01.003","article-title":"Tracheostomy in patients with long-term mechanical ventilation: a survey","volume":"104","author":"Marchese","year":"2010","journal-title":"Respiratory Medicine"},{"key":"10.1002\/14651858.CD016277-BIB0050|cit50","doi-asserted-by":"crossref","first-page":"1106\u201311","DOI":"10.1080\/02699052.2020.1786601","article-title":"Factors associated with tracheostomy decannulation in patients with severe traumatic brain injury","volume":"34","author":"Jenkins","year":"2020","journal-title":"Brain Injury"},{"key":"10.1002\/14651858.CD016277-BIB0051|cit51","doi-asserted-by":"crossref","first-page":"146\u201349","DOI":"10.1007\/PL00009596","article-title":"Simultaneous videofluoroscopic swallow study and modified Evans blue dye procedure: an evaluation of blue dye visualization in cases of known aspiration","volume":"14","author":"Brady","year":"1999","journal-title":"Dysphagia"},{"key":"10.1002\/14651858.CD016277-BIB0052|cit52","first-page":"206\u201311","article-title":"Fiberoptic endoscopic evaluation of swallowing (FEES): proposal for informed consent","volume":"28","author":"Nacci","year":"2008","journal-title":"Acta Otorhinolaryngologica Italica"},{"issue":"3","key":"10.1002\/14651858.CD016277-BIB0053|cit53","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1086\/600391","article-title":"Long-term acute care hospitals","volume":"49","author":"Munoz-Price","year":"2009","journal-title":"Clinical Infectious Diseases"},{"issue":"5","key":"10.1002\/14651858.CD016277-BIB0054|cit54","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.rppneu.2012.04.008","article-title":"Prolonged mechanical ventilation: new facilities and new models of care","volume":"18","author":"Ambrosino","year":"2012","journal-title":"Revista Portuguesa de Pneumolog\u00eda"},{"key":"10.1002\/14651858.CD016277-BIB0055|cit55","doi-asserted-by":"crossref","first-page":"484\u201394","DOI":"10.1007\/s00455-023-10633-7","article-title":"Understanding dysphagia care in Pakistan: a survey of current speech language therapy practice","volume":"39","author":"Akhtar","year":"2024","journal-title":"Dysphagia"},{"key":"10.1002\/14651858.CD016277-BIB0056|cit56","first-page":"1","article-title":"Assessment and management approaches for dysphagia in tracheostomized patients: practices of speech-language pathologists in India","volume":"0","author":"Chilwan","year":"2024","journal-title":"World Journal of Otorhinolaryngology \u2013 Head and Neck Surgery"},{"key":"10.1002\/14651858.CD016277-BIB0057|cit57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s43163-023-00462-8","article-title":"Role of blue dye test as an early predictor of post-laryngectomy pharyngocutaneous fistula","volume":"39","author":"Alsedra","year":"2023","journal-title":"Egyptian Journal of Otolaryngology"},{"key":"10.1002\/14651858.CD016277-BIB0058|cit58","doi-asserted-by":"crossref","first-page":"721\u201329","DOI":"10.1007\/s00455-016-9737-3","article-title":"Diagnostic accuracy of the modified Evan\u2019s blue dye test in detecting aspiration in patients with tracheostomy: a systematic review of the evidence","volume":"31","author":"B\u00e9chet","year":"2016","journal-title":"Dysphagia"},{"issue":"4","key":"10.1002\/14651858.CD016277-BIB0059|cit59","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1001\/jama.2019.18307","article-title":"Preferred reporting items for a systematic review and meta-analysis of diagnostic test accuracy studies: the PRISMA-DTA statement","volume":"319","author":"McInnes","year":"2018","journal-title":"Journal of the American Medical Association"},{"key":"10.1002\/14651858.CD016277-BIB0060|cit60","doi-asserted-by":"crossref","first-page":"213\u201324","DOI":"10.1007\/BF01893104","article-title":"Dynamic imaging of the pharynx","volume":"10","author":"Jones","year":"1985","journal-title":"Gastrointestinal Radiology"},{"key":"10.1002\/14651858.CD016277-BIB0061|cit61","doi-asserted-by":"crossref","first-page":"216\u20139","DOI":"10.1007\/BF02414429","article-title":"Fiberoptic endoscopic examination of swallowing safety: a new procedure","volume":"2","author":"Langmore","year":"1988","journal-title":"Dysphagia"},{"issue":"9","key":"10.1002\/14651858.CD016277-BIB0062|cit62","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1002\/lary.26419","article-title":"Accuracy of endoscopic and videofluoroscopic evaluations of swallowing for oropharyngeal dysphagia","volume":"127","author":"Giraldo-Cadavid","year":"2017","journal-title":"Laryngoscope"},{"key":"10.1002\/14651858.CD016277-BIB0063|cit63","doi-asserted-by":"crossref","first-page":"101598","DOI":"10.1016\/j.bjorl.2025.101598","article-title":"Endoscopic and videofluoroscopic evaluations of swallowing for dysphagia: a systematic review","volume":"91 Suppl 1","author":"Ferrari de Castro","year":"2025","journal-title":"Brazilian Journal of Otorhinolaryngology"},{"key":"10.1002\/14651858.CD016277-BIB0064|cit64","unstructured":"Covidence Veritas Health Innovation 2024"},{"key":"10.1002\/14651858.CD016277-BIB0065|cit65","unstructured":"Review Manager (RevMan) The Cochrane Collaboration 2024"},{"issue":"8","key":"10.1002\/14651858.CD016277-BIB0066|cit66","doi-asserted-by":"publisher","first-page":"529","DOI":"10.7326\/0003-4819-155-8-201110180-00009","article-title":"QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies","volume":"155","author":"Whiting","year":"2011","journal-title":"Annals of Internal Medicine"},{"key":"10.1002\/14651858.CD016277-BIB0067|cit67","unstructured":"Stata StataCorp 2019"},{"key":"10.1002\/14651858.CD016277-BIB0068|cit68","doi-asserted-by":"crossref","unstructured":"Deeks JJ Bossuyt PM Leeflang MM Takwoingi Y Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy Version 2.0 (updated July 2023). The Cochrane Collaboration, 2023 Available from https:\/\/www.cochrane.org\/authors\/handbooks-and-manuals\/handbook-systematic-reviews-diagnostic-test-accuracy","DOI":"10.1002\/14651858.ED000163"},{"key":"10.1002\/14651858.CD016277-BIB0069|cit69","unstructured":"Sch\u00fcnemann H Bro\u017cek J Guyatt G Oxman A Handbook for grading the quality of evidence and the strength of recommendations using the GRADE approach (updated October 2013). GRADE Working Group, 2013 Available from https:\/\/gdt.gradepro.org\/app\/handbook\/handbook.html"},{"key":"10.1002\/14651858.CD016277-BIB0070|cit70","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.jclinepi.2010.07.015","article-title":"GRADE guidelines: 3. Rating the quality of evidence","volume":"64","author":"Balshem","year":"2011","journal-title":"Journal of Clinical Epidemiology"},{"key":"10.1002\/14651858.CD016277-BIB0071|cit71","doi-asserted-by":"crossref","unstructured":"Macaskill P Takwoingi Y Deeks JJ Gatsonis C Macaskill P, Takwoingi Y, Deeks JJ, Gatsonis C. Chapter 9: Understanding meta-analysis. In: Deeks JJ, Bossuyt PM, Leeflang MM, Takwoingi Y, editor(s). Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy . Version 2.0 (updated July 2023). Cochrane, 2023 Available from https:\/\/training.cochrane.org\/handbook-diagnostic-test-accuracy\/current","DOI":"10.1002\/14651858.ED000163"},{"issue":"9","key":"10.1002\/14651858.CD016277-BIB0072|cit72","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.jclinepi.2005.01.016","article-title":"The performance of tests of publication bias and other sample size effects in systematic reviews of diagnostic test accuracy was assessed","volume":"58","author":"Deeks","year":"2005","journal-title":"Journal of Clinical Epidemiology"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","deposited":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T20:35:45Z","timestamp":1765398945000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.CD016277"}},"subtitle":[],"editor":[{"name":"Cochrane Central Editorial Service","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,12,10]]},"references-count":72,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2025,12]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.cd016277","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,10]]}}}