{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T18:55:17Z","timestamp":1790276117625,"version":"4.1.0"},"update-to":[{"DOI":"10.1002\/14651858.mr000007.pub2","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2016,9,6]],"date-time":"2016-09-06T00:00:00Z","timestamp":1473120000000}}],"reference-count":54,"publisher":"Wiley","issue":"9","content-domain":{"domain":["wiley.com","cochranelibrary.com"],"crossmark-restriction":true},"short-container-title":[],"DOI":"10.1002\/14651858.mr000007.pub3","type":"journal-article","created":{"date-parts":[[2016,9,6]],"date-time":"2016-09-06T04:49:03Z","timestamp":1473137343000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Individual participant data meta-analyses compared with meta-analyses based on aggregate data"],"prefix":"10.1002","volume":"2016","author":[{"given":"Catrin","family":"Tudur Smith","sequence":"first","affiliation":[{"name":"The University of Liverpool; Department of Biostatistics; Shelley's Cottage Brownlow Street Liverpool UK L69 3GS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maura","family":"Marcucci","sequence":"additional","affiliation":[{"name":"McMaster University; Department of Clinical Epidemiology and Biostatistics; 1280 Main Street West Hamilton ON Canada L8S 4K1"},{"name":"University of Milan & Geriatric Unit; Department of Clinical Sciences and Community Health; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Via Francesco Sforza, 35 Milan Italy 20122"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah J","family":"Nolan","sequence":"additional","affiliation":[{"name":"The University of Liverpool; Department of Biostatistics; Shelley's Cottage Brownlow Street Liverpool UK L69 3GS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Iorio","sequence":"additional","affiliation":[{"name":"McMaster University; Department of Clinical Epidemiology and Biostatistics; 1280 Main Street West Hamilton ON Canada L8S 4K1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Sudell","sequence":"additional","affiliation":[{"name":"The University of Liverpool; Department of Biostatistics; Shelley's Cottage Brownlow Street Liverpool UK L69 3GS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Riley","sequence":"additional","affiliation":[{"name":"Keele University; Research Institute for Primary Care and Health Sciences; David Weatherall Building, Keele University Campus Staffordshire England UK ST5 5BG"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maroeska M","family":"Rovers","sequence":"additional","affiliation":[{"name":"Radboud University Nijmegen Medical Centre; Department of Operating Rooms; Hp 630, route 631 PO Box 9101 Nijmegen Netherlands 6500 HB"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula R","family":"Williamson","sequence":"additional","affiliation":[{"name":"University of Liverpool; Centre for Medical Statistics and Health Evaluation; Shelley's Cottage Brownlow Street Liverpool Merseyside UK L69 3GS"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,9,6]]},"reference":[{"issue":"3","key":"10.1002\/14651858.MR000007.pub3-BIB0001|cit1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1002\/sim.1023","article-title":"Individual patient- versus group-level data meta-regressions for the investigation of treatment effect modifiers: ecological bias rears its ugly head","volume":"21","author":"Berlin","year":"2002","journal-title":"Statistics in Medicine"},{"issue":"1","key":"10.1002\/14651858.MR000007.pub3-BIB0002|cit2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001545","article-title":"Palliative chemotherapy for advanced or metastatic colorectal cancer","author":"Best","year":"2000","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"5","key":"10.1002\/14651858.MR000007.pub3-BIB0003|cit3","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1001\/jamainternmed.2015.0237","article-title":"Effect of vitamin D supplementation on blood pressure: a systematic review and meta-analysis incorporating individual patient data","volume":"175","author":"Beveridge","year":"2015","journal-title":"JAMA Internal Medicine"},{"issue":"7","key":"10.1002\/14651858.MR000007.pub3-BIB0004|cit4","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1093\/eurheartj\/ehp003","article-title":"Effect of fish oil on ventricular tachyarrhythmia in three studies in patients with implantable cardioverter defibrillators","volume":"30","author":"Brouwer","year":"2009","journal-title":"European Heart Journal"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0005|cit5","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1023\/A:1008468705492","article-title":"Systematic reviews using individual patient data: A map for the minefields?","volume":"9","author":"Clarke","year":"1998","journal-title":"Annals of Oncology"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0006|cit6","doi-asserted-by":"crossref","first-page":"1275-85","DOI":"10.1136\/bmj.316.7140.1275","article-title":"Effectiveness of antibiotic prophylaxis in critically ill adult patients: systematic review of randomised controlled trials","volume":"316","author":"D'Amico","year":"1998","journal-title":"BMJ"},{"issue":"5","key":"10.1002\/14651858.MR000007.pub3-BIB0007|cit7","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/S0197-2456(01)00152-0","article-title":"Individual patient-versus literature-based meta-analysis of survival data: time to event and event rate at a particular time can make a difference, an example based on head and neck cancer","volume":"22","author":"Duchateau","year":"2001","journal-title":"Controlled Clinical Trials"},{"issue":"11","key":"10.1002\/14651858.MR000007.pub3-BIB0008|cit8","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/0895-4356(95)00028-3","article-title":"Validation of a meta-analysis: the effects of fish oil in rheumatoid arthritis","volume":"48","author":"Fortin","year":"1995","journal-title":"Journal of Clinical Epidemiology"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0009|cit9","doi-asserted-by":"crossref","first-page":"183s","DOI":"10.1016\/S0197-2456(97)91213-7","article-title":"Prospective meta-analysis using individual patient data vs meta-analysis of published reports: the case of ACE-inhibitors in myocardial infarction","volume":"18","author":"Franzosi","year":"1997","journal-title":"Controlled Clinical Trials"},{"issue":"4","key":"10.1002\/14651858.MR000007.pub3-BIB0010|cit10","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0895-4356(98)00159-0","article-title":"Recursive cumulative meta-analysis: a diagnostic for the evolution of total randomized evidence from group and individual patient data","volume":"52","author":"Ioannidis","year":"1999","journal-title":"Journal of Clinical Epidemiology"},{"issue":"10","key":"10.1002\/14651858.MR000007.pub3-BIB0011|cit11","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1001\/jama.1995.03530100070037","article-title":"A comparison of meta-analytic results using literature vs individual patient data: Paternal cell immunization for recurrent miscarriage","volume":"274","author":"Jeng","year":"1995","journal-title":"JAMA"},{"issue":"1","key":"10.1002\/14651858.MR000007.pub3-BIB0012|cit12","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1177\/1740774508100984","article-title":"Meta-analysis of individual patient data versus aggregate data from longitudinal clinical trials","volume":"6","author":"Jones","year":"2009","journal-title":"Clinical Trials"},{"issue":"4","key":"10.1002\/14651858.MR000007.pub3-BIB0013|cit13","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1086\/655131","article-title":"Meta-analysis of a possible signal of increased mortality associated with cefepime use","volume":"51","author":"Kim","year":"2010","journal-title":"Clinical Infectious Diseases"},{"issue":"3","key":"10.1002\/14651858.MR000007.pub3-BIB0014|cit14","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1017\/S0266462308080471","article-title":"Empirical comparison of subgroup effects in conventional and individual patient data meta-analyses","volume":"24","author":"Koopman","year":"2008","journal-title":"International Journal of Technology Assessment in Health Care"},{"issue":"5 Suppl","key":"10.1002\/14651858.MR000007.pub3-BIB0015|cit15","doi-asserted-by":"crossref","first-page":"107s","DOI":"10.1378\/chest.109.5_Supplement.107S","article-title":"Chemotherapy for advanced NSCLC: Will meta-analysis provide the answer?","volume":"109","author":"Chevalier","year":"1996","journal-title":"Chest"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0016|cit16","unstructured":"Legg L Leonardi-Bee J Langhorne P Walker M Is getting individual patient data for meta-analyses worthwhile? XI Cochrane Colloquium: Evidence, Health Care and Culture 2003"},{"issue":"4","key":"10.1002\/14651858.MR000007.pub3-BIB0017|cit17","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S1474-4422(05)70044-2","article-title":"Alteplase and ischaemic stroke: have new reviews of old data helped?","volume":"4","author":"Lindley","year":"2005","journal-title":"Lancet Neurology"},{"issue":"3","key":"10.1002\/14651858.MR000007.pub3-BIB0018|cit18","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3747\/co.v13i3.85","article-title":"Maximal androgen blockade for the treatment of metastatic prostate cancer--a systematic review","volume":"13","author":"Lukka","year":"2006","journal-title":"Current Oncology (Toronto, Ont.)"},{"issue":"1","key":"10.1002\/14651858.MR000007.pub3-BIB0019|cit19","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1017\/S0266462305050154","article-title":"Meta-analysis when only the median survival times are known: a comparison with individual patient data results","volume":"21","author":"Michiels","year":"2005","journal-title":"International Journal of Technology Assessment in Health Care"},{"issue":"12","key":"10.1002\/14651858.MR000007.pub3-BIB0020|cit20","doi-asserted-by":"crossref","first-page":"3832","DOI":"10.1200\/JCO.1998.16.12.3832","article-title":"Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: an overview of 6,633 patients from 27 randomized trials","volume":"16","author":"Myeloma Trialists' Collaborative Group","year":"1998","journal-title":"Journal of Clinical Oncology"},{"issue":"11","key":"10.1002\/14651858.MR000007.pub3-BIB0021|cit21","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1200\/JCO.1992.10.11.1819","article-title":"Role of thoracic radiotherapy in limited-stage small-cell lung cancer: quantitative review based on the literature versus meta-analysis based on individual data","volume":"10","author":"Pignon","year":"1992","journal-title":"Journal of Clinical Oncology"},{"issue":"8","key":"10.1002\/14651858.MR000007.pub3-BIB0022|cit22","doi-asserted-by":"crossref","first-page":"2670","DOI":"10.1210\/jc.2011-3328","article-title":"Vitamin D with calcium reduces mortality: patient level pooled analysis of 70,528 patients from eight major vitamin D trials","volume":"97","author":"Rejnmark","year":"2012","journal-title":"Journal of Clinical Endocrinology"},{"issue":"9759","key":"10.1002\/14651858.MR000007.pub3-BIB0023|cit23","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0140-6736(10)62110-1","article-title":"Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials","volume":"377","author":"Rothwell","year":"2011","journal-title":"Lancet"},{"issue":"1","key":"10.1002\/14651858.MR000007.pub3-BIB0024|cit24","first-page":"17","article-title":"Effect of dapsone on survival in HIV infected patients: a meta- analysis of finished trials","volume":"48","author":"Saillourglenisson","year":"2000","journal-title":"Revue d'Epidemiologie et de Sante Publique"},{"issue":"7","key":"10.1002\/14651858.MR000007.pub3-BIB0025|cit25","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.jclinepi.2003.12.001","article-title":"Meta-regression detected associations between heterogeneous treatment effects and study-level, but not patient-level, factors","volume":"57","author":"Schmid","year":"2004","journal-title":"Journal of Clinical Epidemiology"},{"issue":"1","key":"10.1002\/14651858.MR000007.pub3-BIB0026|cit26","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000356.pub3","article-title":"Hospital at home early discharge","author":"Shepperd","year":"2009","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0027|cit27","unstructured":"Spooner C Rowe BH Saunders LD Milner RA Nedocromil sodium as treatment of exercise-induced bronchoconstriction: a comparison of results from a meta-analysis with individual patient data 6th Cochrane Colloquium 1998"},{"issue":"8842","key":"10.1002\/14651858.MR000007.pub3-BIB0028|cit28","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/0140-6736(93)93004-K","article-title":"Meta-analysis of the literature or of individual patient data: is there a difference?","volume":"341","author":"Stewart","year":"1993","journal-title":"Lancet"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0029|cit29","doi-asserted-by":"crossref","first-page":"817","DOI":"10.7326\/0003-4819-128-10-199805150-00004","article-title":"The effect of antilymphocyte induction therapy on renal allograft survival","volume":"128","author":"Szczech","year":"1998","journal-title":"Annals of Internal Medicine"},{"issue":"12","key":"10.1002\/14651858.MR000007.pub3-BIB0030|cit30","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1093\/jjco\/hyh138","article-title":"Individual patient-level and study-level meta-analysis for investigating modifiers of treatment effect","volume":"34","author":"Teramukai","year":"2004","journal-title":"Japanese Journal of Clinical Oncology"},{"issue":"6","key":"10.1002\/14651858.MR000007.pub3-BIB0031|cit31","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1177\/096228020101000602","article-title":"Multilevel models for meta-analysis, and their application to absolute risk differences","volume":"10","author":"Thompson","year":"2001","journal-title":"Statistical Methods in Medical Research"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0032|cit32","doi-asserted-by":"crossref","unstructured":"Tierney J Rydzewska L Burdett S Feasibility and reliability of using hazard ratios in meta-analyses of published time-to-event data 9th Cochrane Colloquium 2001","DOI":"10.1186\/2048-4623-1-S3-OP002"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0033|cit33","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/978-1-4419-7073-2_13","article-title":"Ten years of meta-analyses on erythropoiesis-stimulating agents in cancer patients","volume":"157","author":"Tonia","year":"2011","journal-title":"Cancer Treatment and Research"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0034|cit34","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1111\/1467-985X.00207","article-title":"The value of the aggregate data approach in meta-analysis with time-to-event outcomes","volume":"164","author":"Tudur","year":"2001","journal-title":"Journal of the Royal Statistical Society. Series a (General)"},{"issue":"5","key":"10.1002\/14651858.MR000007.pub3-BIB0035|cit35","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1111\/j.1365-2753.2005.00559.x","article-title":"An overview of methods and empirical comparison of aggregate data and individual patient data results for investigating heterogeneity in meta-analysis of time-to-event outcomes","volume":"11","author":"Tudur Smith","year":"2005","journal-title":"Journal of Evaluation in Clinical Practice"},{"issue":"24","key":"10.1002\/14651858.MR000007.pub3-BIB0036|cit36","doi-asserted-by":"crossref","first-page":"3417","DOI":"10.1002\/1097-0258(20001230)19:24<3417::AID-SIM614>3.0.CO;2-L","article-title":"A multilevel model framework for meta-analysis of clinical trials with binary outcomes","volume":"19","author":"Turner","year":"2000","journal-title":"Statistics in Medicine"},{"issue":"3","key":"10.1002\/14651858.MR000007.pub3-BIB0037|cit37","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.lungcan.2011.12.015","article-title":"Benefits and risks of using erythropoiesis-stimulating agents (ESAs) in lung cancer patients: study-level and patient-level meta-analyses","volume":"76","author":"Vansteenkiste","year":"2012","journal-title":"Lung Cancer (Amsterdam, Netherlands)"},{"issue":"6","key":"10.1002\/14651858.MR000007.pub3-BIB0038|cit38","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1002\/sim.6379","article-title":"Meta-analysis of absolute mean differences from randomised trials with treatment-related clustering associated with care providers","volume":"34","author":"Walwyn","year":"2015","journal-title":"Statistics in Medicine"},{"issue":"2","key":"10.1002\/14651858.MR000007.pub3-BIB0039|cit39","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1046\/j.1365-2753.2000.00236.x","article-title":"Individual patient data meta-analysis of randomized anti-epileptic drug monotherapy trials","volume":"6","author":"Williamson","year":"2000","journal-title":"Journal of Evaluation in Clinical Practice"},{"issue":"344","key":"10.1002\/14651858.MR000007.pub3-BIB0040|cit40","doi-asserted-by":"crossref","first-page":"d7762","DOI":"10.1136\/bmj.d7762","article-title":"Assessment of publication bias, selection bias, and unavailable data in meta-analyses using individual participant data: a database survey","volume":"3","author":"Ahmed","year":"2012","journal-title":"BMJ"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0041|cit41","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1111\/j.1749-6632.1993.tb26345.x","article-title":"The Cochrane Collaboration: preparing, maintaining, and disseminating systematic reviews of the effects of health care","volume":"703","author":"Chalmers","year":"1993","journal-title":"Annals of the New York Academy of Sciences"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0042|cit42","unstructured":"Clarke M Stewart L Individual patient data or published data meta-analysis: a systematic review Proceedings of the Fifth Cochrane Collaboration Colloquium 1997 94, abstract 019.04"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0043|cit43","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1016\/S0140-6736(10)60278-4","article-title":"Elective high-frequency oscillatory versus conventional ventilation in preterm infants: a systematic review and meta-analysis of individual patients' data","volume":"375","author":"Cools","year":"2010","journal-title":"Lancet"},{"issue":"2","key":"10.1002\/14651858.MR000007.pub3-BIB0044|cit44","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1037\/a0015565","article-title":"The relative benefits of meta-analysis conducted with individual participant data versus aggregated data","volume":"14","author":"Cooper","year":"2009","journal-title":"Psychological Methods"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0045|cit45","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1471-2466-12-29","article-title":"Efficacy of once-daily indacaterol 75 \u03bcg relative to alternative bronchodilators in COPD: a study level and a patient level network meta-analysis","volume":"12","author":"Cope","year":"2012","journal-title":"BMC Pulmonary Medicine"},{"issue":"6","key":"10.1002\/14651858.MR000007.pub3-BIB0046|cit46","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1002\/sim.5584","article-title":"Combining individual patient data and aggregate data in mixed treatment comparison meta-analysis: Individual patient data may be beneficial if only for a subset of trials","volume":"32","author":"Donegan","year":"2013","journal-title":"Statistics in Medicine"},{"issue":"8","key":"10.1002\/14651858.MR000007.pub3-BIB0047|cit47","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.MR000026.pub2","article-title":"Checking reference lists to find additional studies for systematic reviews","author":"Horsley","year":"2011","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0048|cit48","doi-asserted-by":"crossref","first-page":"86-94","DOI":"10.1016\/S0895-4356(01)00414-0","article-title":"A comparison of summary patient-level covariates in meta-regressionwith individual patient data meta-analysis","volume":"55","author":"Lambert","year":"2002","journal-title":"Journal of Clinical Epidemiology"},{"issue":"4","key":"10.1002\/14651858.MR000007.pub3-BIB0049|cit49","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1111\/j.0006-341X.1999.01221.x","article-title":"On the equivalence of meta-analysis using literature and using individual patient data","volume":"55","author":"Mathew","year":"1999","journal-title":"Biometrics"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0050|cit50","unstructured":"Mukhtar MA Incorporation of heterogeneity in meta-analysis of randomised controlled trials PhD Thesis 2008"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0051|cit51","doi-asserted-by":"crossref","first-page":"317","DOI":"10.2307\/2534018","article-title":"Comparison of meta-analysis versus analysis of variance of individual patient data","volume":"54","author":"Olkin","year":"1998","journal-title":"Biometrics"},{"key":"10.1002\/14651858.MR000007.pub3-BIB0052|cit52","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1093\/oxfordjournals.aje.a009051","article-title":"Comparison of effect estimates from a meta-analysis of summary data from published studies and from a meta-analysis using individual patient data for ovarian cancer studies","volume":"145","author":"Steinberg","year":"1997","journal-title":"American Journal of Epidemiology"},{"issue":"3","key":"10.1002\/14651858.MR000007.pub3-BIB0053|cit53","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.MR000007","article-title":"Individual patient data meta-analyses compared with meta-analyses based on aggregate data","author":"Clarke","year":"2001","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"2","key":"10.1002\/14651858.MR000007.pub3-BIB0054|cit54","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.MR000007.pub2","article-title":"Individual patient data meta-analyses compared with meta-analyses based on aggregate data","author":"Clarke","year":"2007","journal-title":"Cochrane Database of Systematic Reviews"}],"container-title":["Cochrane Database of Systematic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/14651858.MR000007.pub3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T21:32:26Z","timestamp":1664400746000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1002\/14651858.MR000007.pub3"}},"subtitle":[],"editor":[{"name":"Cochrane Methodology Review Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,9,6]]},"references-count":54,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2016,9]]}},"URL":"https:\/\/doi.org\/10.1002\/14651858.mr000007.pub3","relation":{},"ISSN":["1465-1858"],"issn-type":[{"value":"1465-1858","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,6]]}}}