{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:10:51Z","timestamp":1790244651291,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T00:00:00Z","timestamp":1765929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T00:00:00Z","timestamp":1765929600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Children on anticoagulation have traditionally been discouraged from participating in contact and collision sports due to a perceived bleeding risk. The predictable pharmacokinetics of direct oral anticoagulants permit more individualized management. At Boston Children's Hospital, pharmacokinetic (PK) data were used to develop individualized anticoagulation plans for five athletes on anticoagulation who wished to participate in contact or collision sports. Median (range) duration of follow\u2010up for the cohort was 27 (1\u201342) months. During this period, two patients sustained four sports\u2010related injuries during anticoagulation interruption, but no clinically significant bleeding or recurrent\/progressive thrombosis was observed. All patients safely resumed anticoagulation post\u2010injury.<\/jats:p>","DOI":"10.1002\/1545-5017.70052","type":"journal-article","created":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T10:41:49Z","timestamp":1765968109000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pharmacokinetic\u2010Driven Individualized Anticoagulation Plan for Pediatric Athletes on Direct Oral Anticoagulants"],"prefix":"10.1002","volume":"73","author":[{"given":"Devin","family":"Donnelly","sequence":"first","affiliation":[{"name":"Dana Farber\/Boston Children's Cancer and Blood Disorders Center  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8004-4190","authenticated-orcid":false,"given":"Riten","family":"Kumar","sequence":"additional","affiliation":[{"name":"Dana Farber\/Boston Children's Cancer and Blood Disorders Center  Boston Massachusetts USA"},{"name":"Department of Pediatrics Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2021-054649"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2017013292"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2024015328"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1249\/JSR.0b013e318214d828"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jth.13676"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2018.1.412"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtha.2023.03.004"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rpth.2023.100094"},{"issue":"6","key":"e_1_2_9_10_1","first-page":"1263","article-title":"Clinical Laboratory Measurement of Direct Factor Xa Inhibitors: Anti\u2010Xa Assay Is Preferable to Prothrombin Time Assay","volume":"104","author":"Barrett Y. 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