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We report nine patients with NF1 who presented with concurrent diagnoses of juvenile myelomonocytic leukemia and low\u2010grade glioma, a rare combination. One notable feature of this cohort is that eight patients (89%) harbored nonsense germline\n                    <jats:italic>NF1<\/jats:italic>\n                    variants. This case series highlights the emergence of synchronous or metachronous malignancies in children with NF1 and provides a rationale for heightened awareness of this phenomenon.\n                  <\/jats:p>","DOI":"10.1002\/1545-5017.70060","type":"journal-article","created":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T12:38:51Z","timestamp":1766839131000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Concurrent Juvenile Myelomonocytic Leukemia and Gliomas in Patients With Neurofibromatosis Type 1"],"prefix":"10.1002","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0235-2240","authenticated-orcid":false,"given":"Henry","family":"Hongo","sequence":"first","affiliation":[{"name":"Department of Pediatrics UCSF Benioff Children's Hospitals, University of California San Francisco  San Francisco California USA"},{"name":"School of Medicine Loma Linda University  Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah K.","family":"Tasian","sequence":"additional","affiliation":[{"name":"Division of Oncology and Center for Childhood Cancer Research Children's Hospital of Philadelphia  Philadelphia Pennsylvania USA"},{"name":"Department of Pediatrics and Abramson Cancer Center University of Pennsylvania School of Medicine  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alix E.","family":"Seif","sequence":"additional","affiliation":[{"name":"Division of Oncology and Center for Childhood Cancer Research Children's Hospital of Philadelphia  Philadelphia Pennsylvania USA"},{"name":"Department of Pediatrics and Abramson Cancer Center University of Pennsylvania School of Medicine  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0471-9883","authenticated-orcid":false,"given":"Jenna","family":"Rossoff","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology Oncology and Stem Cell Transplantation Ann &amp; Robert H. 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