{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T21:24:55Z","timestamp":1783113895250,"version":"3.54.6"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","award":["Doctoral Research Fellow 303289"],"award-info":[{"award-number":["Doctoral Research Fellow 303289"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp;amp; Cancer"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK Principal Treatment Centres (PTCs). Our study explored the key barriers and facilitators to implementing photobiomodulation into standard care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>CYP, their parents, and healthcare professionals (HCPs) were purposively sampled for diversity in theoretically important characteristics: stage of adoption of PTC, professional role (HCPs), age (CYP), and photobiomodulation modality. Initial deductive framework analysis on semi\u2010structured interview data was guided by the Consolidated Framework for Implementation Research (CFIR). Qualitative summaries were then inductively generated, articulating the valence of influence and effect. Overarching themes were developed and refined in collaboration with patient involvement groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010seven participants were interviewed: 18 HCPs from 11 diverse PTCs, 1 industry representative, and 4 CYP\/Parent dyads. Participants had experience with low\u2010level laser (\n                      <jats:italic>n<\/jats:italic>\n                      = 15) and light\u2010emitting diode (LED) (\n                      <jats:italic>n<\/jats:italic>\n                      = 13) systems. Perceived barriers and facilitators varied between PTCs, participant groups, and photobiomodulation systems. Five themes were developed: (1) framing photobiomodulation as essential to routine care in busy cancer services; (2) photobiomodulation as simple, proactive, and rewarding; (3) need for navigable, interconnected, multiprofessional networks to support implementation; (4) balancing individualisation of services with the need for guidance and standardisation; and (5) increasing implementation of LED systems, with fewer barriers, over time.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Implementing photobiomodulation in paediatric oncology depends less on its clinical evidence and more on the local conditions that enable reliable delivery. This study highlights the importance of aligning service structures, workforce capacity, and professional networks to \u2018embed\u2019 photobiomodulation as routine care. Theory\u2010informed implementation strategies can reduce current inequities in access and provide a transferable model for introducing other evidence\u2010based supportive care interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/1545-5017.70282","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T09:37:45Z","timestamp":1777455465000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Why and When Are Evidence\u2010Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation"],"prefix":"10.1002","volume":"73","author":[{"given":"Claudia","family":"Heggie","sequence":"first","affiliation":[{"name":"Paediatric Dentistry School of Dentistry University of Leeds  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kara A.","family":"Gray\u2010Burrows","sequence":"additional","affiliation":[{"name":"Behavioural Sciences &amp; Complex Intervention Methodology School of Dentistry University of Leeds  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9711-9638","authenticated-orcid":false,"given":"Peter F.","family":"Day","sequence":"additional","affiliation":[{"name":"Children's Oral Health &amp; Paediatric Dentistry School of Dentistry University of Leeds and Community Dental Service, Leeds Bradford District Care NHS Foundation Trust, Bradford  UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4938-9673","authenticated-orcid":false,"given":"Bob","family":"Phillips","sequence":"additional","affiliation":[{"name":"Paediatrics and Evidence Synthesis &amp; Paediatric Oncology University of York  York UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl A.","family":"Thompson","sequence":"additional","affiliation":[{"name":"Applied Health Research School of Healthcare University of Leeds  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,29]]},"reference":[{"key":"e_1_2_18_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40368\u2010022\u201000727\u20105"},{"key":"e_1_2_18_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010011\u20101343\u20101"},{"key":"e_1_2_18_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild\u20102024\u2010327529"},{"key":"e_1_2_18_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1368\u20108375(97)00053\u20105"},{"key":"e_1_2_18_6_1","doi-asserted-by":"publisher","DOI":"10.5863\/1551\u20106776\u201017.4.340"},{"key":"e_1_2_18_7_1","doi-asserted-by":"publisher","DOI":"10.1109\/jstqe.2016.2561201"},{"key":"e_1_2_18_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431\u2010017\u20103043\u20104"},{"key":"e_1_2_18_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild\u20102020\u2010321216"},{"key":"e_1_2_18_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjspcare\u20102014\u2010000804"},{"key":"e_1_2_18_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2021.05.013"},{"key":"e_1_2_18_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.31978"},{"key":"e_1_2_18_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010022\u201007450\u20103"},{"key":"e_1_2_18_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1748\u20105908\u20101\u20101"},{"key":"e_1_2_18_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjqs\u20102018\u2010009036"},{"key":"e_1_2_18_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/intqhc\/mzm042"},{"key":"e_1_2_18_17_1","volume-title":"Specialist Hospitals","author":"Children's Cancer and Young People's Cancer Association","year":"2025"},{"key":"e_1_2_18_18_1","volume-title":"Diffusion of Innovations","author":"Rogers E. 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