{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:01:42Z","timestamp":1777942902194,"version":"3.51.4"},"reference-count":13,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:00:00Z","timestamp":1775088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:00:00Z","timestamp":1775088000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp;amp; Cancer"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Childhood cancer survivors face lifelong risks requiring ongoing monitoring. We report three cases of survivors who subsequently developed colon polyps in their teens or twenties within 10 years of completing cancer treatment. They presented with gastrointestinal symptoms, leading to early colonoscopies revealing tubular adenomas and other polyps. None had a family history of colon cancer or positive germline testing. Two had a history of astrocytoma, and one a history of relapsed T\u2010cell acute lymphoblastic leukemia; all had high cyclophosphamide equivalent doses (CED) of chemotherapy, and some received radiation. These observations suggest a diagnosis of therapy\u2010associated polyposis (TAP) linked to alkylating agents in addition to radiation and the need for heightened clinical awareness of TAP in cancer survivors.<\/jats:p>","DOI":"10.1002\/1545-5017.70301","type":"journal-article","created":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T10:36:46Z","timestamp":1775126206000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Therapy\u2010Associated Polyposis in Pediatric Cancer Survivors"],"prefix":"10.1002","volume":"73","author":[{"given":"Sue L.","family":"Jaspersen","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Hematology and Oncology Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea V.","family":"Stacy","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Hematology and Oncology Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2916-9335","authenticated-orcid":false,"given":"Kalin","family":"Kyte","sequence":"additional","affiliation":[{"name":"Division of Genetics and Genomic Medicine Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer D.","family":"Henry","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Hematology and Oncology Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4056-4084","authenticated-orcid":false,"given":"David A.","family":"Rudnick","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Nutrition Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David B.","family":"Wilson","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Hematology and Oncology Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katie","family":"Gettinger","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Hematology and Oncology Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,4,2]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1158\/1940\u20106207.CAPR\u201019\u20100416"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/JXX.0000000000000474"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2013.11.040"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.14309\/crj.0000000000001379"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/S11938\u2010019\u201000251\u20104"},{"key":"e_1_2_5_7_1","unstructured":"NCCN Survivorship Care for Cancer\u2010Related Late and Long\u2010Term EffectsAccessed March 23 2026.https:\/\/www.nccn.org\/patients\/guidelines\/content\/PDF\/survivorship\u2010crl\u2010patient.pdf."},{"key":"e_1_2_5_8_1","unstructured":"Children's Oncology GroupAccessed August 25 2025.https:\/\/www.survivorshipguidelines.org\/."},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/PBC.24679"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/BLOOD\u20102010\u201006\u2010292615"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/APT.13800"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/CNCR.29987"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620\u2010011\u20101972\u20108"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.5946\/ce.2018.046"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/1545-5017.70301","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/1545-5017.70301","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/1545-5017.70301","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:10:14Z","timestamp":1777705814000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/1545-5017.70301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,2]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/1545-5017.70301"],"URL":"https:\/\/doi.org\/10.1002\/1545-5017.70301","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,2]]},"assertion":[{"value":"2025-11-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70301"}}