{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:01:51Z","timestamp":1777942911771,"version":"3.51.4"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:00:00Z","timestamp":1775088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:00:00Z","timestamp":1775088000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp;amp; Cancer"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>X\u2010linked sideroblastic anemia (XLSA) is categorized as hypochromic microcytic anemia. In 3 children with XLSA, we observed prominent elliptocytosis, and red cell band 3 content histograms were similar to those found in hereditary elliptocytosis, thus validating Cooley's descriptions in 1945.<\/jats:p>","DOI":"10.1002\/1545-5017.70313","type":"journal-article","created":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T10:21:31Z","timestamp":1775125291000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cooley's Legacy Endures\u2014Elliptocytes in X\u2010Linked Sideroblastic Anemia Due to Aminolevulinate Synthase 2 Mutations"],"prefix":"10.1002","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5136-1525","authenticated-orcid":false,"given":"Alex","family":"Ciurej","sequence":"first","affiliation":[{"name":"Children's Hospital of Michigan  Detroit Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7138-3027","authenticated-orcid":false,"given":"S\u00fcreyya","family":"Sava\u015fan","sequence":"additional","affiliation":[{"name":"Children's Hospital of Michigan Division of Hematology\/Oncology Transplant and Cellular Therapy Program Karmanos Cancer Institute  Detroit Michigan USA"},{"name":"Department of Pediatrics Central Michigan University College of Medicine  Mt. Pleasant Michigan USA"},{"name":"Division of Hematology\/Oncology Children's Hospital of Michigan  Detroit Michigan USA"},{"name":"Hematology\/Oncology Flow Cytometry Laboratory Children's Hospital of Michigan  Detroit Michigan USA"},{"name":"Department of Pediatrics Wayne State University School of Medicine  Detroit Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7479-1349","authenticated-orcid":false,"given":"Kanta","family":"Bhambhani","sequence":"additional","affiliation":[{"name":"Children's Hospital of Michigan Division of Hematology\/Oncology Transplant and Cellular Therapy Program Karmanos Cancer Institute  Detroit Michigan USA"},{"name":"Department of Pediatrics Central Michigan University College of Medicine  Mt. Pleasant Michigan USA"},{"name":"Department of Pediatrics Wayne State University School of Medicine  Detroit Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8366-9487","authenticated-orcid":false,"given":"Manisha","family":"Gadgeel","sequence":"additional","affiliation":[{"name":"Hematology\/Oncology Flow Cytometry Laboratory Children's Hospital of Michigan  Detroit Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5884-6776","authenticated-orcid":false,"given":"Madhvi","family":"Rajpurkar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Central Michigan University College of Medicine  Mt. Pleasant Michigan USA"},{"name":"Division of Hematology\/Oncology Children's Hospital of Michigan  Detroit Michigan USA"},{"name":"Hematology\/Oncology Flow Cytometry Laboratory Children's Hospital of Michigan  Detroit Michigan USA"},{"name":"Department of Pediatrics Wayne State University School of Medicine  Detroit Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9577-9624","authenticated-orcid":false,"given":"Yaddanapudi","family":"Ravindranath","sequence":"additional","affiliation":[{"name":"Hematology\/Oncology Flow Cytometry Laboratory Children's Hospital of Michigan  Detroit Michigan USA"},{"name":"Department of Pediatrics Wayne State University School of Medicine  Detroit Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,4,2]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2014.04.008"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000441\u2010194606000\u201000001"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood\u20102018\u201008\u2010815951"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2000.02416.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI109888"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-199605000-00005"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2020.00636"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/108.4.391"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcmd.2015.09.001"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V84.8.2823.2823"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms2899"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.07370"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2024024294"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.20049"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-194505000-00001"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V84.11.3915.bloodjournal84113915"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/1545-5017.70313","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/1545-5017.70313","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/1545-5017.70313","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:10:29Z","timestamp":1777705829000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/1545-5017.70313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,2]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/1545-5017.70313"],"URL":"https:\/\/doi.org\/10.1002\/1545-5017.70313","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,2]]},"assertion":[{"value":"2025-12-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70313"}}