{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:35:27Z","timestamp":1787758527966,"version":"build-2784847793"},"reference-count":10,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Paronychia is a frequent cutaneous adverse event associated with MEK inhibitor therapy and may significantly impair quality of life and compromise treatment adherence. Treatment is usually medical, with poor and unsustained results. We retrospectively evaluated the safety and efficacy of CO\n                    <jats:sub>2<\/jats:sub>\n                    laser matrixectomy in children at a tertiary center between 2016 and 2026. Five patients with prolonged symptoms despite multiple conservative treatments were identified. Complete resolution was achieved in all patients, with no procedure\u2010related complications. MEK inhibitor therapy was continued without recurrence of paronychia. Outcomes remained favorable during a mean follow\u2010up of 4 years.\n                  <\/jats:p>","DOI":"10.1002\/1545-5017.70466","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T03:50:11Z","timestamp":1785383411000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["CO\n                    <sub>2<\/sub>\n                    Laser Matrixectomy for Refractory MEK Inhibitor\u2013Induced Paronychia in Children: A Case Series"],"prefix":"10.1002","volume":"73","author":[{"given":"Rivka","family":"Friedland","sequence":"first","affiliation":[{"name":"Pediatric Dermatology Unit Schneider Children's Medical Center of Israel  Petah Tikva Israel"},{"name":"School of Medicine, Gray Faculty of Medical and Health Sciences Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yehonatan","family":"Noyman","sequence":"additional","affiliation":[{"name":"School of Medicine, Gray Faculty of Medical and Health Sciences Tel Aviv University  Tel Aviv Israel"},{"name":"Laser Unit, Division of Dermatology Rabin Medical Center  Petah Tikva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4735-2890","authenticated-orcid":false,"given":"Assi","family":"Levi","sequence":"additional","affiliation":[{"name":"School of Medicine, Gray Faculty of Medical and Health Sciences Tel Aviv University  Tel Aviv Israel"},{"name":"Laser Unit, Division of Dermatology Rabin Medical Center  Petah Tikva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rony","family":"Cohen","sequence":"additional","affiliation":[{"name":"School of Medicine, Gray Faculty of Medical and Health Sciences Tel Aviv University  Tel Aviv Israel"},{"name":"Institute of Pediatric Neurology Schneider Children's Medical Center of Israel  Petah Tikva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1476-7937","authenticated-orcid":false,"given":"Helen","family":"Toledano","sequence":"additional","affiliation":[{"name":"School of Medicine, Gray Faculty of Medical and Health Sciences Tel Aviv University  Tel Aviv Israel"},{"name":"Department of Pediatric Hematology\u2010Oncology Schneider Children's Medical Center of Israel  Petah Tikva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13038"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.07.044"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000539374"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/nop\/npae038"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13205"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000003036"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.14079"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.14276"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2002.22028.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2012.04546.x"}],"container-title":["Pediatric Blood &amp; 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