{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:17:29Z","timestamp":1787761049858,"version":"build-2784847793"},"reference-count":41,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100006058","name":"St. Baldrick's Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006058","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Sleep disturbances are associated with increased fatigue, reduced quality of life, and neurocognitive dysfunction and have emerged as a common complication among pediatric cancer survivors. Sleep disturbances are particularly concerning given their potential to exacerbate existing neurocognitive impacts of cancer treatments. This pilot study examined the feasibility and acceptability of a home\u2010wearable EEG\u2010based sleep device (Sleep Profiler\n                      <jats:sup>TM<\/jats:sup>\n                      ) for acute lymphoblastic leukemia (ALL) survivors as well as associations between specific sleep parameters and neurocognitive functioning.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Procedure<\/jats:title>\n                    <jats:p>\n                      Children (ages 8\u201312;\n                      <jats:italic>M<\/jats:italic>\n                      = 10 years,\n                      <jats:italic>SD<\/jats:italic>\n                      = 1.6;\n                      <jats:italic>N<\/jats:italic>\n                      = 23) &gt;6 months post\u2010treatment for ALL were enrolled at clinical visits and wore the Sleep Profiler\n                      <jats:sup>TM<\/jats:sup>\n                      for two consecutive nights at home, followed by neurocognitive testing of attention, inhibitory control, working memory, and processing speed. Parents completed subjective measures of child sleep, anxiety, depression, and acceptability. Feasibility reflected the percentage of children wearing the device at least one night and the percentage of nights with good EEG quality data.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      All participants wore the device both nights, with 84% meeting the threshold for good quality measurement. Few children met recommended quantity and quality sleep thresholds based on objective measurement, including 5 patients with elevated snoring levels; 43.5% of subjective ratings fell above the threshold for sleep disturbance. Greater sleep latency was associated with worse inhibitory control (\n                      <jats:italic>r<\/jats:italic>\n                      = \u22120.42,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.046), and total sleep time was positively associated with inhibitory control and attention.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Findings confirm the feasibility and acceptability of home EEG sleep monitoring in school\u2010age survivors, and associations of sleep latency and snoring with reduced neurocognitive functioning may offer modifiable risk factors for aspects of neuropsychological dysfunction common in pediatric survivorship.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Trial Registration<\/jats:title>\n                    <jats:p>At the time this study was conducted, we were not required to register the study on ClinicalTrials.gov. It was a single\u2010institution feasibility study without intervention, which was not considered a clinical trial.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/1545-5017.70476","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T03:50:48Z","timestamp":1785383448000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Wearable Sleep Monitoring in Pediatric Acute Lymphoblastic Leukemia: Associations With Subjective Sleep Ratings and Neurocognitive Functioning"],"prefix":"10.1002","volume":"73","author":[{"given":"Kathy","family":"Ruble","sequence":"first","affiliation":[{"name":"Johns Hopkins School of Medicine Pediatric Oncology Baltimore  Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Northrup","sequence":"additional","affiliation":[{"name":"Kennedy Krieger Institute, Center for Neuropsychological and Psychological Assessment Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomer","family":"Nusinov","sequence":"additional","affiliation":[{"name":"Kennedy Krieger Institute, Center for Neuropsychological and Psychological Assessment Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa A.","family":"Jacobson","sequence":"additional","affiliation":[{"name":"Kennedy Krieger Institute, Center for Neuropsychological and Psychological Assessment Baltimore Maryland USA"},{"name":"Psychiatry and Behavioral Sciences Johns Hopkins School of Medicine Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,29]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.64.3205"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsaa086"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215\u20100366(16)30283\u20108"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/1043454209358890"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/23809000.2016.1168265"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2009.10.004"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12519\u2010022\u201000647\u2010w"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2015.04.053"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2017.05.002"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2015.03.016"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsaa043"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010010\u20100921\u2010y"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25797"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.15\u20101365"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsaf090.1002"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.6618"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102869.1996.00251.x"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2010.07.005"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10802\u2010010\u20109460\u20108"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0005\u20107967(99)00130\u20108"},{"key":"e_1_2_9_22_1","doi-asserted-by":"crossref","unstructured":"D.Wechsler Wechsler Intelligence Scale for Children\u2013Fifth Edition (APA PsycTests 2014) https:\/\/doi.org\/10.1037\/t79359\u2010000.","DOI":"10.1037\/t79359-000"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/1087054712464269"},{"key":"e_1_2_9_24_1","unstructured":"M.WolfandM. 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