{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:17:51Z","timestamp":1787761071609,"version":"build-2784847793"},"reference-count":25,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Childhood cancer survivors (CCS) are at increased risk of obesity and related cardiometabolic complications. Evidence for multidisciplinary (MD) lifestyle interventions in CCS, particularly from low\u2013 and middle\u2010income countries (LMICs), remains limited, and long\u2010term adherence is poorly understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We conducted a prospective single\u2010arm interventional study among overweight and obese CCS attending a survivorship clinic at a tertiary cancer centre between January 2021 and June 2022. Participants received a structured MD intervention including dietary counselling, physical activity guidance and psychological support, with telephonic reinforcement up to 24 weeks. Outcomes assessed at 1 year included BMI\n                      <jats:italic>z<\/jats:italic>\n                      \u2010score, physical activity, functional endurance (6\u2010min walk test), dietary intake and sedentary behaviour. Factors associated with response were explored using logistic regression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sixty CCS (median age 15 years) were enrolled. At 1 year, mean BMI\n                      <jats:italic>z<\/jats:italic>\n                      \u2010score decreased modestly from 2.13\u00a0\u00b1\u00a00.69 to 1.8\u00a0\u00b1\u00a00.7 (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.01). Significant improvements were observed in physical activity levels, 6\u2010min walk distance (507.8\u2013600\u00a0m,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) and sedentary time (11.5\u20139.0\u00a0h\/day,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). Dietary patterns showed reduced caloric and fat intake with improved protein consumption. Adherence to intervention components declined progressively after cessation of structured reinforcement at 24 weeks. Younger age and lower BMI at cancer diagnosis were associated with better response.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>MD lifestyle interventions integrated into survivorship care are feasible in an LMIC setting and improved behavioural and functional outcomes, with modest reduction in BMI. Declining adherence over time emphasises need for sustained reinforcement strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/1545-5017.70499","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T04:58:12Z","timestamp":1785387492000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility and Impact of a Multidisciplinary Lifestyle Intervention Among Overweight and Obese Childhood Cancer Survivors in a Low\u2013 and Middle\u2010Income Setting"],"prefix":"10.1002","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0720-8336","authenticated-orcid":false,"given":"Gauri","family":"Kapoor","sequence":"first","affiliation":[{"name":"Department of Pediatric Hematology Oncology &amp; BMT Rajiv Gandhi Cancer Institute and Research Centre  Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navneet","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy Rajiv Gandhi Cancer Institute and Research Centre  Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology Oncology &amp; BMT Rajiv Gandhi Cancer Institute and Research Centre  Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakshi","family":"Dudeja","sequence":"additional","affiliation":[{"name":"Department of Dietetics Rajiv Gandhi Cancer Institute and Research Centre  Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Payal","family":"Malhotra","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology Oncology &amp; BMT Rajiv Gandhi Cancer Institute and Research Centre  Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jahnvi","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Psycho\u2010Oncology Rajiv Gandhi Cancer Institute and Research Centre  Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aayushi","family":"Khaneja","sequence":"additional","affiliation":[{"name":"Department of Psycho\u2010Oncology Rajiv Gandhi Cancer Institute and Research Centre  Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juhi","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Psycho\u2010Oncology Rajiv Gandhi Cancer Institute and Research Centre  Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khushi","family":"Jha","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology Oncology &amp; BMT Rajiv Gandhi Cancer Institute and Research Centre  Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3482-0774","authenticated-orcid":false,"given":"Anurag","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Statistics Ram Lal Anand College, University of Delhi  Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,29]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1200\/GO.22.00044"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0000000000000249"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijmr.IJMR_196_16"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2021.104754"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.3945\/an.115.008946"},{"issue":"3","key":"e_1_2_12_7_1","article-title":"Addressing the Challenge: A Review of Effective Prevention Strategies for Childhood Obesity in India","volume":"16","author":"Jambholkar P. 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