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Complete tumor resection is the cornerstone of treatment, with meticulous attention to preventing tumor spillage. Risk stratification of adjuvant chemotherapy decisions incorporates tumor stage and critical parameters, including histological differentiation and mitotic rate. Optimal patient management requires treatment within cooperative networks providing centralized histopathological review and comprehensive genetic testing, multidisciplinary tumor board evaluation, and prospective registry enrollment to advance knowledge for these exceptionally rare malignancies.<\/jats:p>","DOI":"10.1002\/1545-5017.70571","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T08:20:35Z","timestamp":1785140435000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ovarian Sex Cord Stromal Tumors in Children and Adolescents\u2014The European Standard Clinical Practice Recommendations"],"prefix":"10.1002","volume":"73","author":[{"given":"Dominik T.","family":"Schneider","sequence":"first","affiliation":[{"name":"Clinic of Pediatrics Klinikum Dortmund  Dortmund Germany"},{"name":"University Witten\/Herdecke  Witten 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