{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T14:00:00Z","timestamp":1790172000440,"version":"4.1.0"},"reference-count":59,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Blood &amp;amp; Cancer"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Pain is a common and clinically significant complication of pediatric hematopoietic cell transplantation (HCT). It evolves across conditioning, engraftment, early recovery, and survivorship, and may result from mucosal injury, procedures, graft\u2010versus\u2010host disease (GVHD), infection, medication toxicity, immobility, and long\u2010term complications. Pediatric HCT\u2010specific guidance remains limited, so practice is often extrapolated from broader pediatric oncology, adult HCT, and supportive\/palliative care literature. This narrative review summarizes major pain phenotypes after pediatric HCT and emphasizes developmentally appropriate, repeated assessment; phenotype\u2010based pharmacologic management; and multimodal care integrating opioids, adjuvant analgesics, nonpharmacologic strategies, rehabilitation, child life, psychology, pharmacy, and palliative care. Evidence remains fragmented. Future work should prioritize standardized pain phenotyping, patient\u2010 and proxy\u2010reported outcomes, longitudinal assessment of pain and function, and multicenter supportive\u2010care pathways extending beyond acute transplant.<\/jats:p>","DOI":"10.1002\/1545-5017.70661","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T08:45:32Z","timestamp":1788425132000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pain Management After Pediatric Hematopoietic Cell Transplantation: A Narrative Review of Pain Phenotypes, Assessment, and Multimodal Care"],"prefix":"10.1002","volume":"73","author":[{"given":"Ayodeji","family":"Otufowora","sequence":"first","affiliation":[{"name":"Division of Pediatric Hematology Oncology and Stem Cell Transplantation Department of Pediatrics Columbia University Irving Medical Center  New York New York 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