{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T09:36:21Z","timestamp":1777628181597,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T00:00:00Z","timestamp":1769990400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T00:00:00Z","timestamp":1769990400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["24FC2004"],"award-info":[{"award-number":["24FC2004"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The efficacy of plasma exchange (PEx) in patients with anti\u2010glomerular basement membrane antibody (anti\u2010GBM Ab) disease requiring renal replacement therapy (RRT) at diagnosis remains unclear. This study aimed to investigate the outcomes and safety of patients with uremic anti\u2010GBM Ab disease undergoing PEx.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed nine patients confirmed by renal biopsy who received PEx using fresh frozen plasma or 5% human albumin solution and underwent hemodialysis (HD) concomitantly with standard immunosuppressive therapy. The outcome was determined as dialysis dependency, and safety was evaluated for adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Two patients (22.2%) achieved dialysis independence at 10 and 11\u2009months. Both patients had relatively preserved normal glomeruli (15.8%\u201337.2%) and achieved early remission. Retroperitoneal hemorrhage and recalcitrant anti\u2010GBM Ab were noteworthy in other cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PEx can facilitate renal recovery in selected patients with anti\u2010GBM disease requiring RRT. Pathological evaluation may be useful to determine the intensity and duration of treatment, including PEx.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/1744-9987.70121","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T04:26:53Z","timestamp":1770092813000},"page":"353-362","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Plasma Exchange for Anti\u2010\n                    <scp>GBM<\/scp>\n                    Disease With Dialysis Dependency: A Case Series on Clinical Outcomes and Safety"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-5108-7137","authenticated-orcid":false,"given":"Minoru","family":"Sakuragi","sequence":"first","affiliation":[{"name":"Department of Nephrology and Dialysis Medical Research Institute Kitano Hospital, PIIF Tazuke\u2010Kofukai  Osaka Japan"},{"name":"Department of Biomedical Data Intelligence, Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miho","family":"Miyauchi","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis Medical Research Institute Kitano Hospital, PIIF Tazuke\u2010Kofukai  Osaka Japan"},{"name":"Department of Medicine, Division of Diabetology, Endocrinology and Nephrology Shiga University of Medical Science  Otsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Misaki","family":"Kubo","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis Medical Research Institute Kitano Hospital, PIIF Tazuke\u2010Kofukai  Osaka Japan"},{"name":"Department of Nephrology Tottori Prefectural Central Hospital  Tottori Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mea","family":"Aso","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis Medical Research Institute Kitano Hospital, PIIF Tazuke\u2010Kofukai  Osaka Japan"},{"name":"Division of Nephrology and Hypertension, Department of Internal Medicine St. Marianna University School of Medicine  Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanae","family":"Ogura","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis Medical Research Institute Kitano Hospital, PIIF Tazuke\u2010Kofukai  Osaka Japan"},{"name":"Center for Preventive Medicine Medical Research Institute Kitano Hospital, PIIF Tazuke\u2010Kofukai  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuko","family":"Sokai","sequence":"additional","affiliation":[{"name":"Department of Clinical Engineering Medical Research Institute Kitano Hospital, PIIF Tazuke\u2010Kofukai  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Tsuji","sequence":"additional","affiliation":[{"name":"Department of Clinical Engineering Medical Research Institute Kitano Hospital, PIIF Tazuke\u2010Kofukai  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keita P.","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis Medical Research Institute Kitano Hospital, PIIF Tazuke\u2010Kofukai  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Torikoshi","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis Medical Research Institute Kitano Hospital, PIIF Tazuke\u2010Kofukai  Osaka Japan"},{"name":"Katagiri Memorial Clinic  Niigata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis Medical Research Institute Kitano Hospital, PIIF Tazuke\u2010Kofukai  Osaka Japan"},{"name":"Division of Nephrology and Dialysis Ozawa Hospital  Odawara 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