{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:28:12Z","timestamp":1787498892941,"version":"build-2736575974"},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:00:00Z","timestamp":1775692800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:00:00Z","timestamp":1775692800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>This study aimed to assess the short\u2010term antioxidant effects of a vitamin E\u2010coated membrane during continuous kidney replacement therapy (CKRT) based on the neutrophil\u2010to\u2010lymphocyte ratio (NLR) and red cell distribution width (RDW).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>CKRT sessions conducted between December 2023 and May 2025 at a single tertiary\u2010care center were retrospectively analyzed. Based on the type of hemofilter used, sessions were categorized into polysulfone membrane (PS) and vitamin E\u2010coated membrane (VE) groups. Laboratory parameters at CKRT initiation and 48\u2009h thereafter were compared between the two groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 79 CKRT sessions (33 patients) were analyzed. In the PS group, NLR and RDW\u2010SD increased significantly (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01 and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03), whereas no significant changes were observed in the VE group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Vitamin E\u2010coated membranes may exert short\u2010term antioxidant effects during CKRT by reducing inflammatory and oxidative responses as reflected by NLR and RDW.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/1744-9987.70135","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:35:27Z","timestamp":1775781327000},"page":"530-535","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Short\u2010Term Antioxidant Effects of Vitamin E\u2010Coated Filters During Continuous Kidney Replacement Therapy in Critically Ill Patients"],"prefix":"10.1002","volume":"30","author":[{"given":"Masahiro","family":"Kawamura","sequence":"first","affiliation":[{"name":"Advanced Emergency and Critical Care Center Kurume University Hospital  Kurume Japan"},{"name":"Clinical Engineering Center Kurume University Hospital  Kurume Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6979-1419","authenticated-orcid":false,"given":"Masafumi","family":"Fukuda","sequence":"additional","affiliation":[{"name":"Advanced Emergency and Critical Care 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