{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T09:36:45Z","timestamp":1777628205603,"version":"3.51.4"},"reference-count":11,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Selective plasma exchange (SePE) using the Evacure Plus EC\u20104A10D selective membrane separator is a useful therapeutic option for removing immunoglobulin G (IgG) in autoimmune diseases while retaining coagulation factors, including fibrinogen. This study aimed to clarify the clinical usefulness of SePE in pediatric autoimmune neurological disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We reported five pediatric patients with pediatric autoimmune neurological disorders successfully treated with SePE. We analyzed the removal rates of IgG and fibrinogen in a total of 29 SePE sessions and 3 conventional plasma exchange (PE) sessions performed on five pediatric patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Clinical symptoms improved in all patients without coagulation factor supplementation, and no severe adverse events of SePE\/PE were observed. The mean IgG removal rates were similar for SePE and PE, at 55.5% and 61.8%, respectively. In contrast, the mean fibrinogen removal rate was lower for SePE than for PE, at 17.9% and 61.3%, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>SePE might be effective for pediatric autoimmune neurological disorders.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/1744-9987.70136","type":"journal-article","created":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T00:45:22Z","timestamp":1773967522000},"page":"412-417","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Usefulness of Selective Plasma Exchange for Treating Pediatric Autoimmune Neurological Diseases"],"prefix":"10.1002","volume":"30","author":[{"given":"Tomoya","family":"Nakamizo","sequence":"first","affiliation":[{"name":"Department of Pediatrics and Developmental Biology Institute of Science Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toru","family":"Kanamori","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Developmental Biology Institute of Science Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoya","family":"Kaneda","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Developmental Biology Institute of Science Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kei","family":"Osaka","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Developmental Biology Institute of Science Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miki","family":"Murakoshi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Developmental Biology Institute of Science Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mika","family":"Okutsu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Developmental Biology Institute of Science Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Ohkubo","sequence":"additional","affiliation":[{"name":"Medical Engineering Center Medical Hospital of Institute of Science Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7177-6426","authenticated-orcid":false,"given":"Tomohiro","family":"Udagawa","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Developmental Biology Institute of Science Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8451-6909","authenticated-orcid":false,"given":"Tomoko","family":"Mizuno","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Developmental Biology Institute of Science Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shotaro","family":"Naito","sequence":"additional","affiliation":[{"name":"Department of Nephrology Institute of Science Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7580-9184","authenticated-orcid":false,"given":"Masatoshi","family":"Takagi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Developmental Biology Institute of Science Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1077-7772","authenticated-orcid":false,"given":"Masaki","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Perinatal and Maternal Medicine Institute of Science Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.12114"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2017.08.010"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.12346"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21513"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.12464"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000001052"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.14959"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.16073"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.5301\/ijao.5000435"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.12465"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.12674"}],"container-title":["Therapeutic 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Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/1744-9987.70136","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/1744-9987.70136","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/1744-9987.70136","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T01:31:46Z","timestamp":1777426306000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/1744-9987.70136"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,19]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/1744-9987.70136"],"URL":"https:\/\/doi.org\/10.1002\/1744-9987.70136","archive":["Portico"],"relation":{},"ISSN":["1744-9979","1744-9987"],"issn-type":[{"value":"1744-9979","type":"print"},{"value":"1744-9987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,19]]},"assertion":[{"value":"2025-10-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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