{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T17:21:35Z","timestamp":1783012895902,"version":"3.54.6"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Pre\u2010dilution online hemodiafiltration (Pre\u2010HDF) is predominantly used in Japan, whereas post\u2010dilution online HDF (Post\u2010HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility. This study compared biocompatibility and solute removal performance between Pre\u2010 and Post\u2010HDF using the ATA membrane.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Eight stable maintenance hemodialysis patients underwent both Pre\u2010 (60\u2009L\/session) and Post\u2010HDF (12\u2009L\/session) using an ATA membrane. Blood flow rate was 250\u2009mL\/min, total dialysate flow rate was 500\u2009mL\/min, and treatment time was 4\u2009h. Biocompatibility and solute removal parameters were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>White blood cell and platelet counts showed mild decreases; inflammatory markers remained unchanged in both modalities. CD62P expression increased more in Post\u2010HDF. Reduction rates of urea, creatinine, and \u03b11\u2010microglobulin were higher in Post\u2010HDF, while \u03b22\u2010microglobulin was comparable. Albumin leakage was greater in Post\u2010HDF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Using the ATA membrane, Pre\u2010 and Post\u2010HDF showed comparable biocompatibility, while Post\u2010HDF provided superior solute removal performance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/1744-9987.70147","type":"journal-article","created":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T04:21:15Z","timestamp":1775708475000},"page":"523-529","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-4776-8945","authenticated-orcid":false,"given":"Kenji","family":"Sakurai","sequence":"first","affiliation":[{"name":"Dialysis Center, Hashimoto Clinic  Sagamihara Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshitaka","family":"Kurihara","sequence":"additional","affiliation":[{"name":"Dialysis Center, Hashimoto Clinic  Sagamihara Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumi","family":"Yamauchi","sequence":"additional","affiliation":[{"name":"Dialysis Center, Hashimoto Clinic  Sagamihara Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromi","family":"Hosoya","sequence":"additional","affiliation":[{"name":"Dialysis Center, Hashimoto Clinic  Sagamihara Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Saito","sequence":"additional","affiliation":[{"name":"Dialysis Center, Hashimoto Clinic  Sagamihara Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,8]]},"reference":[{"issue":"12","key":"e_1_2_12_2_1","first-page":"543","article-title":"Annual Dialysis Data Report, JSDT Renal Data Registry","volume":"57","author":"Masaki T.","year":"2023","journal-title":"Journal of the Japanese Society for Dialysis Therapy"},{"key":"e_1_2_12_3_1","unstructured":"Japanese Society for Dialysis Therapy \u201cWADDA System Ver2.1 \u201d(2025.1.16 Search; Age and HDF Dilution Method for End of Year 2023 Facility Hemodialysis Patients) https:\/\/member.jsdt.or.jp\/member\/statistics."},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)31694-5"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfx277"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10047-013-0698-0"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10047-021-01281-5"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/prca.201700140"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10047-018-1062-1"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M708535200"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000346364"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2011.4282"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfac160"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10047-020-01167-y"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41100-025-00678-9"}],"container-title":["Therapeutic Apheresis and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/1744-9987.70147","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/1744-9987.70147","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/1744-9987.70147","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T16:47:50Z","timestamp":1783010870000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/1744-9987.70147"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,8]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/1744-9987.70147"],"URL":"https:\/\/doi.org\/10.1002\/1744-9987.70147","archive":["Portico"],"relation":{},"ISSN":["1744-9979","1744-9987"],"issn-type":[{"value":"1744-9979","type":"print"},{"value":"1744-9987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,8]]},"assertion":[{"value":"2026-01-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}