{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T20:01:32Z","timestamp":1785268892009,"version":"3.55.0"},"reference-count":60,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:00:00Z","timestamp":1783987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:00:00Z","timestamp":1783987200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health\u2010related quality of life. Intradialytic exercise has been proposed as a non\u2010pharmacological strategy to improve these outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Randomized clinical trial with 35 hemodialysis patients randomly allocated to a resistance group (RG) or aerobic group (AG). Exercises were performed during hemodialysis for 12\u2009weeks. The primary outcome was handgrip strength (HGS). Secondary outcomes included the 30\u2010second sit\u2010to\u2010stand test (30sec\u2010STS), gait speed (GS), frailty, fatigue, sleep quality, and health\u2010related quality of life (HRQL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In intragroup analyses, RG improved HGS (MD: 2.4; 95% CI: 0.3\u20134.5), 30sec\u2010STS, GS, mental fatigue, and sleep quality, whereas AG improved 30sec\u2010STS, GS, and HRQL measured by EQ\u2010VAS. In intergroup analyses, AG was more effective than RG in reducing general fatigue (MD: 2.2; 95% CI: 0.4\u20134.0) and improving HRQL utility (MD: \u22120.04; 95% CI: \u22120.10 to \u22120.04). No significant between\u2010group differences were observed for HGS or the other outcomes. No adverse events or harms were reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Resistance and aerobic intradialytic exercise were both feasible and safe. Resistance exercise improved handgrip strength within\u2010group; however, no significant between\u2010group difference was observed for handgrip strength (the primary outcome). Aerobic exercise was more effective in improving general fatigue and health\u2010related quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/1744-9987.70175","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T07:55:13Z","timestamp":1784015713000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9595-9182","authenticated-orcid":false,"given":"Klebson","family":"da Silva Almeida","sequence":"first","affiliation":[{"name":"Master's and Doctoral Program in Physical Therapy Universidade Cidade de S\u00e3o Paulo \u2013 UNICID  S\u00e3o Paulo Brazil"},{"name":"Center University Fibra \u2013 FIBRA  Bel\u00e9m Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6826-4278","authenticated-orcid":false,"given":"Gisela Cristiane","family":"Miyamoto","sequence":"additional","affiliation":[{"name":"Master's and Doctoral Program in Physical Therapy Universidade Cidade de S\u00e3o Paulo \u2013 UNICID  S\u00e3o Paulo Brazil"},{"name":"Department of Health Sciences Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo \u2013 FMRP\u2010USP  Ribeirao Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8820-1645","authenticated-orcid":false,"given":"Daniel","family":"da Costa Torres","sequence":"additional","affiliation":[{"name":"Master's and Doctoral Program in Physical Therapy Universidade Cidade de S\u00e3o Paulo \u2013 UNICID  S\u00e3o Paulo Brazil"},{"name":"Center University Fibra \u2013 FIBRA  Bel\u00e9m Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6616-5254","authenticated-orcid":false,"given":"Ian Setubal Reis","family":"Chaves","sequence":"additional","affiliation":[{"name":"Center University Fibra \u2013 FIBRA  Bel\u00e9m Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8837-9125","authenticated-orcid":false,"given":"Jonas","family":"do Carmo Paschoalin","sequence":"additional","affiliation":[{"name":"Center University Fibra \u2013 FIBRA  Bel\u00e9m Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2477-5164","authenticated-orcid":false,"given":"Bra\u00falio Lima","family":"Nascimento","sequence":"additional","affiliation":[{"name":"Methodist University of Piracicaba \u2013 UNIMEP  Piracicaba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6374-3002","authenticated-orcid":false,"given":"Luciana Dias","family":"Chiavegato","sequence":"additional","affiliation":[{"name":"Master's and Doctoral Program in Physical Therapy Universidade Cidade de S\u00e3o Paulo \u2013 UNICID  S\u00e3o Paulo Brazil"},{"name":"Federal University of S\u00e3o Paulo \u2013 UNIFESP  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)32977-0"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/2175-8239-jbn-2018-0178"},{"issue":"4","key":"e_1_2_10_4_1","doi-asserted-by":"crossref","first-page":"S117","DOI":"10.1016\/j.kint.2023.10.018","article-title":"KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease","volume":"105","author":"Kidney Disease: Improving Global Outcomes CKDWG","year":"2024","journal-title":"Kidney International"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2019.01.034"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gft070"},{"issue":"10","key":"e_1_2_10_7_1","first-page":"1921","article-title":"Chronic Kidney Disease: Prevention and Treatment of Common Complications","volume":"70","author":"Snively C. 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