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We discovered and sequenced a novel 4.4 kb human linc<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content> called linc\u20109432 in pterygium, an ocular disease characterized by a wedge lesion. This transcript inhibited differentiation\u2010induced cell death, promoted expression of stem cell markers, and decreased expression of epithelial and mesenchymal differentiation markers. This linc<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content> regulated 30 differentiation\u2010related genes in transcriptome analysis and 17\/30 gene products were known to be directly associated in a network. When the linc<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content> was silenced with pooled si<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>, the levels of these transcripts decreased in accordance with their predicted binding affinity for the linc<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">TBC<\/jats:styled-content>1D8B had the strongest affinity, interacting <jats:italic>in\u2010vitro<\/jats:italic> at positions 269\u2013292 within <jats:styled-content style=\"fixed-case\">TBC<\/jats:styled-content>1D8B.<\/jats:p>","DOI":"10.1002\/1873-3468.13027","type":"journal-article","created":{"date-parts":[[2018,3,7]],"date-time":"2018-03-07T16:12:09Z","timestamp":1520439129000},"page":"1173-1184","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Linc\u20109432 is a novel pterygium linc<scp>RNA<\/scp> which regulates 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