{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T13:23:19Z","timestamp":1788009799648,"version":"build-2784847793"},"reference-count":264,"publisher":"Wiley","issue":"24","license":[{"start":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T00:00:00Z","timestamp":1576022400000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["EY013124"],"award-info":[{"award-number":["EY013124"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["EY021558"],"award-info":[{"award-number":["EY021558"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["EY014104"],"award-info":[{"award-number":["EY014104"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007745","name":"Massachusetts Lions Eye Research Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007745","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["febs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["FEBS Letters"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:p>Human adenovirus commonly causes infections of respiratory, gastrointestinal, genitourinary, and ocular surface mucosae. Although most adenovirus eye infections are mild and self\u2010limited, specific viruses within human adenovirus species D are associated with epidemic keratoconjunctivitis (EKC), a severe and highly contagious ocular surface infection, which can lead to chronic and\/or recurrent, visually disabling keratitis. In this review, we discuss the links between adenovirus ontogeny, genomics, immune responses, and corneal pathogenesis, for those viruses that cause EKC.<\/jats:p>","DOI":"10.1002\/1873-3468.13693","type":"journal-article","created":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T10:01:55Z","timestamp":1574762515000},"page":"3583-3608","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Genomic foundations of evolution and ocular pathogenesis in human adenovirus species D"],"prefix":"10.1002","volume":"593","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8694-7235","authenticated-orcid":false,"given":"Ashrafali Mohamed","family":"Ismail","sequence":"first","affiliation":[{"name":"Massachusetts Eye and Ear Harvard Medical School Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohong","family":"Zhou","sequence":"additional","affiliation":[{"name":"Massachusetts Eye and Ear Harvard Medical School Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David W.","family":"Dyer","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology University of Oklahoma Health Sciences Center OK USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald","family":"Seto","sequence":"additional","affiliation":[{"name":"Bioinformatics and Computational Biology Program School of Systems Biology George Mason University Manassas VA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaya","family":"Rajaiya","sequence":"additional","affiliation":[{"name":"Massachusetts Eye and Ear Harvard Medical School Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7463-1599","authenticated-orcid":false,"given":"James","family":"Chodosh","sequence":"additional","affiliation":[{"name":"Massachusetts Eye and Ear Harvard Medical School Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,11]]},"reference":[{"key":"e_1_2_12_2_1","first-page":"125","volume-title":"Virus Taxonomy: Classification and Nomenclature of Viruses: Ninth Report of the International Committee on Taxonomy of Viruses","author":"Harrach B","year":"2012"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.137.3533.835"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.48.12.2051"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.8.3171"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(77)90180-5"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.76.2.655"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(85)80079-9"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.32.371.426"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.122.3181.1190-a"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-92-22394"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-84-20714"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep01812"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890070204"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0005635"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.7883\/yoken.64.353"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2010.10.020"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.12-9656"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1099\/jgv.0.000968"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2014.09.009"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00116-13"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.5.3.262"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.gt.3302036"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-10-557"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0125954"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0078679"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.80.4.1688-1699.2006"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2014.05.030"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00720-16"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.4218"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis670"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis671"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.17.6763"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(12)70345-6"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/166.4.769"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2019.1588113"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1006\/mthe.2001.0575"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3002925"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1411627"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01597-10"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.71.1.398-404.1997"},{"key":"e_1_2_12_42_1","first-page":"783","article-title":"Adenovirus keratitis: a role for interleukin\u20108","volume":"41","author":"Chodosh J","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_12_43_1","first-page":"837","article-title":"Keratitis punctata superficialis","author":"Fuchs E","year":"1889","journal-title":"Wien Klin Wochenschr"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5126.873"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.14.11.595"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.14.6.257"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(42)91318-7"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197312202892504"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(55)91856-0"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(57)90433-6"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(57)91484-8"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1961.tb03518.x"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196305092681901"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.60.7.1230"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2018.07.008"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2018.08.033"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu225"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2206.151898"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2402.171407"},{"key":"e_1_2_12_60_1","first-page":"71","article-title":"Viruria in man","volume":"6","author":"Utz JP","year":"1964","journal-title":"Prog Med Virol"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196803282781303"},{"key":"e_1_2_12_62_1","first-page":"1242","article-title":"Adenovirus infection of the urinary tract","volume":"1","year":"1968","journal-title":"Lancet"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197308162890704"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0212434"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjm.2015.11.011"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02650-06"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.296.6617.229-a"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(79)91853-1"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.20.3.365-372.1984"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.386"},{"key":"e_1_2_12_71_1","first-page":"95","article-title":"An outbreak of pharyngoconjunctival fever caused by types 3 and 4 adenovirus at Waalwijk, The Netherlands","volume":"68","author":"Van Der Veen J","year":"1958","journal-title":"Am J Hyg"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.8.3644-3648.2004"},{"key":"e_1_2_12_73_1","first-page":"637","article-title":"Adenovirus\u2010associated epidemic keratoconjunctivitis outbreaks\u2013four states, 2008\u20132010","volume":"62","author":"Centers for Disease Control and Prevention (CDC)","year":"2013","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ico.0000170693.13326.fb"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0502.990212"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0908.030190"},{"key":"e_1_2_12_77_1","first-page":"1407","volume-title":"Manual of Clinical Microbiology","author":"Swenson PD","year":"2003"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400064809"},{"key":"e_1_2_12_79_1","first-page":"9","article-title":"A primary school outbreak of pharyngoconjunctival fever caused by adenovirus type 3","volume":"25","author":"Harley D","year":"2001","journal-title":"Commun Dis Intell"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.59.12.1182"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.2807\/ese.14.08.19125-en"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.06523-11"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004290050160"},{"key":"e_1_2_12_84_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268815003246"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2018.02.016"},{"key":"e_1_2_12_86_1","first-page":"10","article-title":"Genomic analysis of a large set of currently\u2010and historically\u2010important human adenovirus pathogens","volume":"7","author":"Ismail AM","year":"2018","journal-title":"Emerg Microbes Infect"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.80118-0"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-9-213"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1408462111"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.str.2011.03.023"},{"key":"e_1_2_12_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2008.06.026"},{"key":"e_1_2_12_92_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1995.tb00298.x"},{"key":"e_1_2_12_93_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3704642"},{"key":"e_1_2_12_94_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1187292"},{"key":"e_1_2_12_95_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4614-0980-9_3"},{"key":"e_1_2_12_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81516-0"},{"key":"e_1_2_12_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.str.2011.06.004"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.70.3.1836-1844.1996"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature04721"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2009.06.041"},{"key":"e_1_2_12_101_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.68.6.4104-4106.1994"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.275.5304.1320"},{"key":"e_1_2_12_103_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.286.5444.1579"},{"key":"e_1_2_12_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm952"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.8.3897-3905.2004"},{"key":"e_1_2_12_106_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2267"},{"key":"e_1_2_12_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2004.11.041"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.1038\/44880"},{"key":"e_1_2_12_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(58)90050-3"},{"key":"e_1_2_12_110_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.24.15265-15276.2005"},{"key":"e_1_2_12_111_1","first-page":"120","article-title":"A hemagglutination\u2010inhibition technique for typing adenoviruses","volume":"71","author":"Rosen L","year":"1960","journal-title":"Am J Hyg"},{"key":"e_1_2_12_112_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01044-10"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02289-09"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.7883\/yoken.65.457"},{"key":"e_1_2_12_115_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.02178"},{"key":"e_1_2_12_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90231-E"},{"key":"e_1_2_12_117_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.11.5405-5409.2001"},{"key":"e_1_2_12_118_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02019-16"},{"key":"e_1_2_12_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1702(99)00087-8"},{"key":"e_1_2_12_120_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-28255-7"},{"key":"e_1_2_12_121_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.72.3.2388-2397.1998"},{"key":"e_1_2_12_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2005.03.077"},{"key":"e_1_2_12_123_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00595-12"},{"key":"e_1_2_12_124_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.2.1053-1061.2005"},{"key":"e_1_2_12_125_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00936-14"},{"key":"e_1_2_12_126_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01694-09"},{"key":"e_1_2_12_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2013.09.025"},{"key":"e_1_2_12_128_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a121632"},{"key":"e_1_2_12_129_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00282-09"},{"key":"e_1_2_12_130_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01928-09"},{"key":"e_1_2_12_131_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02225-12"},{"key":"e_1_2_12_132_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep07365"},{"key":"e_1_2_12_133_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2211.160728"},{"key":"e_1_2_12_134_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2306.161848"},{"key":"e_1_2_12_135_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2016.03.002"},{"key":"e_1_2_12_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2018.02.050"},{"key":"e_1_2_12_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2018.04.001"},{"key":"e_1_2_12_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2011.04.031"},{"key":"e_1_2_12_139_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.11.5375-5380.2001"},{"key":"e_1_2_12_140_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.13.7225-7235.2003"},{"key":"e_1_2_12_141_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.70.11.7614-7621.1996"},{"key":"e_1_2_12_142_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.3.1100-1108.2002"},{"key":"e_1_2_12_143_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.2.1157-1162.2003"},{"key":"e_1_2_12_144_1","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.83142-0"},{"key":"e_1_2_12_145_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-08599-y"},{"key":"e_1_2_12_146_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-13-2-345"},{"key":"e_1_2_12_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(72)90249-8"},{"key":"e_1_2_12_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(68)90189-X"},{"key":"e_1_2_12_149_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-0004(99)01413-9"},{"key":"e_1_2_12_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81229-5"},{"key":"e_1_2_12_151_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.161004898"},{"key":"e_1_2_12_152_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01407"},{"key":"e_1_2_12_153_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a016550"},{"key":"e_1_2_12_154_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-79499-5_4"},{"key":"e_1_2_12_155_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(80)90464-X"},{"key":"e_1_2_12_156_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0042-6822(83)80014-2"},{"key":"e_1_2_12_157_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.51.3.571-577.1984"},{"key":"e_1_2_12_158_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(80)90564-4"},{"key":"e_1_2_12_159_1","doi-asserted-by":"publisher","DOI":"10.1086\/507533"},{"key":"e_1_2_12_160_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-107-26648"},{"key":"e_1_2_12_161_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00786-09"},{"key":"e_1_2_12_162_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2009.04.019"},{"key":"e_1_2_12_163_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2015.08.018"},{"key":"e_1_2_12_164_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1959.8.492"},{"key":"e_1_2_12_165_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400068789"},{"key":"e_1_2_12_166_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197406202902512"},{"key":"e_1_2_12_167_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/132.2.142"},{"key":"e_1_2_12_168_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2008.10.001"},{"key":"e_1_2_12_169_1","first-page":"113","article-title":"Mechanisms of E3 modulation of immune and inflammatory responses","volume":"273","author":"Fessler SP","year":"2004","journal-title":"Curr Top Microbiol Immunol"},{"key":"e_1_2_12_170_1","first-page":"29","article-title":"Immune evasion by adenovirus E3 proteins: exploitation of intracellular trafficking pathways","volume":"273","author":"Windheim M","year":"2004","journal-title":"Curr Top Microbiol Immunol"},{"key":"e_1_2_12_171_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-59421-2_16"},{"key":"e_1_2_12_172_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1999.tb01287.x"},{"key":"e_1_2_12_173_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01927-13"},{"key":"e_1_2_12_174_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.06969-11"},{"key":"e_1_2_12_175_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.22328"},{"key":"e_1_2_12_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2013.05.014"},{"key":"e_1_2_12_177_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2013.09.009"},{"key":"e_1_2_12_178_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00564-19"},{"key":"e_1_2_12_179_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000841"},{"key":"e_1_2_12_180_1","first-page":"2879","article-title":"Specific NFkappaB subunit activation and kinetics of cytokine induction in adenoviral keratitis","volume":"15","author":"Rajaiya J","year":"2009","journal-title":"Mol Vis"},{"key":"e_1_2_12_181_1","doi-asserted-by":"publisher","DOI":"10.1093\/genetics\/77.3.425"},{"key":"e_1_2_12_182_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.53.2.451"},{"key":"e_1_2_12_183_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(89)90125-3"},{"key":"e_1_2_12_184_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.6.2244"},{"key":"e_1_2_12_185_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(85)90070-4"},{"key":"e_1_2_12_186_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80315-3"},{"key":"e_1_2_12_187_1","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.05026-11"},{"key":"e_1_2_12_188_1","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00105-18"},{"key":"e_1_2_12_189_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2012.04.009"},{"key":"e_1_2_12_190_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1206.050245"},{"key":"e_1_2_12_191_1","doi-asserted-by":"publisher","DOI":"10.3390\/v11050395"},{"key":"e_1_2_12_192_1","doi-asserted-by":"publisher","DOI":"10.3390\/v11030247"},{"key":"e_1_2_12_193_1","doi-asserted-by":"publisher","DOI":"10.3390\/v11030242"},{"key":"e_1_2_12_194_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5OB01025J"},{"key":"e_1_2_12_195_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.73.4.2798-2802.1999"},{"key":"e_1_2_12_196_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01010-16"},{"key":"e_1_2_12_197_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25041"},{"key":"e_1_2_12_198_1","first-page":"1","article-title":"Epidemic kerato\u2010conjunctivitis; new era of required clinical practices due to the emergence of novel recombinant types in human mastadenovirus D","volume":"1","author":"Gonzalez G","year":"2017","journal-title":"J Clin Ophthalmol Eye Disorders"},{"key":"e_1_2_12_199_1","first-page":"225","volume-title":"Am Soc Virol 27th Annu Meet","author":"Fahnestock PKS","year":"2008"},{"key":"e_1_2_12_200_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/172.3.629"},{"key":"e_1_2_12_201_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-199503000-00010"},{"key":"e_1_2_12_202_1","doi-asserted-by":"publisher","DOI":"10.1089\/10445490260099782"},{"key":"e_1_2_12_203_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.170.12.6234"},{"key":"e_1_2_12_204_1","first-page":"2685","article-title":"Activation of focal adhesion kinase in adenovirus\u2010infected human corneal fibroblasts","volume":"43","author":"Natarajan K","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_12_205_1","doi-asserted-by":"publisher","DOI":"10.1186\/1743-422X-5-17"},{"key":"e_1_2_12_206_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.05-0724"},{"key":"e_1_2_12_207_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.6b00858"},{"key":"e_1_2_12_208_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi3007127"},{"key":"e_1_2_12_209_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.19.12332-12341.2005"},{"key":"e_1_2_12_210_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0077462"},{"key":"e_1_2_12_211_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2019.01.008"},{"key":"e_1_2_12_212_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1350-9462(98)00033-0"},{"key":"e_1_2_12_213_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-5155(97)00115-9"},{"key":"e_1_2_12_214_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(00)00088-9"},{"key":"e_1_2_12_215_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI115093"},{"key":"e_1_2_12_216_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11626-015-9910-2"},{"key":"e_1_2_12_217_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.77.8.4494"},{"key":"e_1_2_12_218_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1992.01080200147043"},{"key":"e_1_2_12_219_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-199409000-00011"},{"key":"e_1_2_12_220_1","first-page":"574","article-title":"An ocular model of adenovirus type 5 infection in the NZ rabbit","volume":"33","author":"Gordon YJ","year":"1992","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_12_221_1","first-page":"2740","article-title":"Studies of adenovirus\u2010induced eye disease in the rabbit model","volume":"36","author":"Trousdale MD","year":"1995","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_12_222_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-5944"},{"key":"e_1_2_12_223_1","first-page":"33","article-title":"An ocular model of adenovirus type 5 infection in the rabbit","volume":"259","author":"De Hauwere B","year":"1995","journal-title":"Bull Soc Belge Ophtalmol"},{"key":"e_1_2_12_224_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200204000-00010"},{"key":"e_1_2_12_225_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2003.08.003"},{"key":"e_1_2_12_226_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200108000-00020"},{"key":"e_1_2_12_227_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.05-1270"},{"key":"e_1_2_12_228_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-3542(95)00962-0"},{"key":"e_1_2_12_229_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-199505000-00009"},{"key":"e_1_2_12_230_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(86)90406-X"},{"key":"e_1_2_12_231_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.5.1651"},{"key":"e_1_2_12_232_1","first-page":"346","article-title":"Human adenovirus type 37 and the BALB\/c mouse: progress toward a restricted adenovirus keratitis model (an American Ophthalmological Society thesis)","volume":"104","author":"Chodosh J","year":"2006","journal-title":"Trans Am Ophthalmol Soc"},{"key":"e_1_2_12_233_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.06-1036"},{"key":"e_1_2_12_234_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.14-15635"},{"key":"e_1_2_12_235_1","doi-asserted-by":"publisher","DOI":"10.1089\/jir.2009.0006"},{"key":"e_1_2_12_236_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2016.05.016"},{"key":"e_1_2_12_237_1","doi-asserted-by":"publisher","DOI":"10.1038\/icb.2016.73"},{"key":"e_1_2_12_238_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2015.12.013"},{"key":"e_1_2_12_239_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02392-08"},{"key":"e_1_2_12_240_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00562-10"},{"key":"e_1_2_12_241_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0024859"},{"key":"e_1_2_12_242_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a120913"},{"key":"e_1_2_12_243_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.164.supplement_2.2106063"},{"key":"e_1_2_12_244_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25441"},{"key":"e_1_2_12_245_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000233542.48267.fd"},{"key":"e_1_2_12_246_1","doi-asserted-by":"publisher","DOI":"10.1002\/1873-3468.13576"},{"key":"e_1_2_12_247_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2016.02.007"},{"key":"e_1_2_12_248_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.23736"},{"key":"e_1_2_12_249_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/158.4.804"},{"key":"e_1_2_12_250_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2005.09.005"},{"key":"e_1_2_12_251_1","doi-asserted-by":"publisher","DOI":"10.1159\/000150325"},{"key":"e_1_2_12_252_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.12.3940-3945.1999"},{"key":"e_1_2_12_253_1","doi-asserted-by":"publisher","DOI":"10.1089\/088922299309937"},{"key":"e_1_2_12_254_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-009-0539-x"},{"key":"e_1_2_12_255_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0024491"},{"key":"e_1_2_12_256_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0033212"},{"key":"e_1_2_12_257_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.23331"},{"key":"e_1_2_12_258_1","doi-asserted-by":"publisher","DOI":"10.1128\/genomeA.01267-13"},{"key":"e_1_2_12_259_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01319812"},{"key":"e_1_2_12_260_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005415"},{"key":"e_1_2_12_261_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.162.12.7534"},{"key":"e_1_2_12_262_1","doi-asserted-by":"publisher","DOI":"10.1128\/CDLI.7.2.279-287.2000"},{"key":"e_1_2_12_263_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01844-08"},{"key":"e_1_2_12_264_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0000000000000451"},{"key":"e_1_2_12_265_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms7090351"}],"container-title":["FEBS Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/1873-3468.13693","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/1873-3468.13693","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/1873-3468.13693","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T01:56:55Z","timestamp":1694138215000},"score":1,"resource":{"primary":{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/10.1002\/1873-3468.13693"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":264,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["10.1002\/1873-3468.13693"],"URL":"https:\/\/doi.org\/10.1002\/1873-3468.13693","archive":["Portico"],"relation":{},"ISSN":["0014-5793","1873-3468"],"issn-type":[{"value":"0014-5793","type":"print"},{"value":"1873-3468","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"2019-10-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}