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However, little information is available regarding the effects of \u03b2\u2010CAS activity changes on plant resistance to environmental stress. Here, we found that \u03b2\u2010CAS overexpression (CAS\u2010OE) improves the resistance of tobacco plants to salt stress, whereas plants with \u03b2\u2010CAS silencing suffer more oxidative damage than wild\u2010type plants. Notably, blocking respiration by the alternative oxidase (AOX) pathway significantly aggravates stress injury and impairs the salt stress tolerance mediated by CAS\u2010OE. These findings present novel insights into the synergistic effect between \u03b2\u2010CAS and AOX in protecting plants from salt stress, where \u03b2\u2010CAS plays a vital role in restraining cyanide accumulation, and AOX helps to alleviate the toxic effect of cyanide.<\/jats:p>","DOI":"10.1002\/1873-3468.13723","type":"journal-article","created":{"date-parts":[[2019,12,20]],"date-time":"2019-12-20T07:50:30Z","timestamp":1576828230000},"page":"1284-1295","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Overexpressed \u03b2\u2010cyanoalanine synthase functions with alternative oxidase to improve tobacco resistance to salt stress by alleviating oxidative damage"],"prefix":"10.1002","volume":"594","author":[{"given":"Lu\u2010Lu","family":"Yu","sequence":"first","affiliation":[{"name":"Applied Biotechnology Center Wuhan University of Bioengineering 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