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Compared with other MAP kinases, the biological roles of ERK7 remain poorly understood. Recent work, however, has revealed several novel functions for ERK7. These include a highly conserved essential role in ciliogenesis, the ability to control cell growth, metabolism and autophagy, as well as the maintenance of genomic integrity. ERK7 functions through phosphorylation\u2010dependent and \u2010independent mechanisms and it is activated by cellular stressors, including DNA\u2010damaging agents, and nutrient deprivation. 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