{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:15:37Z","timestamp":1786976137371,"version":"build-2736575974"},"reference-count":157,"publisher":"Wiley","issue":"20","license":[{"start":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T00:00:00Z","timestamp":1731369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011659","name":"L\u00e9ka\u0159sk\u00e1 fakulta, Masarykova univerzita","doi-asserted-by":"publisher","award":["MUNI\/A\/1558\/2023"],"award-info":[{"award-number":["MUNI\/A\/1558\/2023"]}],"id":[{"id":"10.13039\/501100011659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011659","name":"L\u00e9ka\u0159sk\u00e1 fakulta, Masarykova univerzita","doi-asserted-by":"publisher","award":["MUNI\/A\/1685\/2024"],"award-info":[{"award-number":["MUNI\/A\/1685\/2024"]}],"id":[{"id":"10.13039\/501100011659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003243","name":"Ministerstvo Zdravotnictv\u00ed Cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["MH CZ\u2010DRO 65269705"],"award-info":[{"award-number":["MH CZ\u2010DRO 65269705"]}],"id":[{"id":"10.13039\/501100003243","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003243","name":"Ministerstvo Zdravotnictv\u00ed Cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["NW24\u201003\u201000369"],"award-info":[{"award-number":["NW24\u201003\u201000369"]}],"id":[{"id":"10.13039\/501100003243","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["febs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["FEBS Letters"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:p>\n                    FoxO transcription factors (FoxO1, FoxO3a, FoxO4, FoxO6) are a highly evolutionary conserved subfamily of the \u2018forkhead\u2019 box proteins. They have traditionally been considered tumor suppressors, but FoxO1 also exhibits oncogenic properties. The complex nature of FoxO1 is illustrated by its various roles in B cell development and differentiation, immunoglobulin gene rearrangement and cell\u2010surface B cell receptor (BCR) structure, DNA damage control, cell cycle regulation, and germinal center reaction. FoxO1 is tightly regulated at a transcriptional (STAT3, HEB, EBF, FoxOs) and post\u2010transcriptional level (Akt, AMPK, CDK2, GSK3, IKKs, JNK, MAPK\/Erk, SGK1, miRNA). In B cell malignancies, recurrent\n                    <jats:italic>FoxO1<\/jats:italic>\n                    activating mutations (S22\/T24) and aberrant nuclear export and activity have been described, underscoring the potential of its therapeutic inhibition. Here, we review FoxO1's roles across B cell and myeloid malignancies, namely acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL), follicular lymphoma (FL), diffuse large B cell lymphoma (DLBCL), mantle cell lymphoma (MCL), Burkitt lymphoma (BL), Hodgkin lymphoma (HL), and multiple myeloma (MM). We also discuss preclinical evidence for FoxO1 targeting by currently available inhibitors (AS1708727, AS1842856, cpd10).\n                  <\/jats:p>","DOI":"10.1002\/1873-3468.15057","type":"journal-article","created":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T07:30:55Z","timestamp":1731483055000},"page":"2911-2931","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["<scp>FoxO1<\/scp>\n                    signaling in B cell malignancies and its therapeutic targeting"],"prefix":"10.1002","volume":"599","author":[{"given":"Krystof","family":"Hlavac","sequence":"first","affiliation":[{"name":"Central European Institute of Technology Masaryk University  Brno Czech Republic"},{"name":"Department of Internal Medicine, Hematology and Oncology University Hospital Brno and Faculty of Medicine  Brno Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Pavelkova","sequence":"additional","affiliation":[{"name":"Central European Institute of Technology Masaryk University  Brno Czech Republic"},{"name":"Department of Internal Medicine, Hematology and Oncology University Hospital Brno and Faculty of Medicine  Brno Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Ondrisova","sequence":"additional","affiliation":[{"name":"Central European Institute of Technology Masaryk University  Brno Czech Republic"},{"name":"Department of Internal Medicine, Hematology and Oncology University Hospital Brno and Faculty of Medicine  Brno Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6975-8838","authenticated-orcid":false,"given":"Marek","family":"Mraz","sequence":"additional","affiliation":[{"name":"Central European Institute of Technology Masaryk University  Brno Czech Republic"},{"name":"Department of Internal Medicine, Hematology and Oncology University Hospital Brno and Faculty of Medicine  Brno Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.12.029"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1667"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.08.041"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2015.10.015"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2015.10.021"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-09-381905"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2019001393"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2018029546"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI160767"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI173770"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-01-479865"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1124\/mol.110.065714"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2010.07.018"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.str.2008.06.013"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells8090966"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M704735200"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2008.09.025"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2008.20"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M302804200"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1179101"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.253500"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1111766108"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M808848200"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2015.103"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-07-795278"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2011.05.001"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2017.07.008"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.21.10.3534-3546.2001"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80595-4"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.24.17184"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1474-9726.2008.00420.x"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi050618r"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.002725"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.069062"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M708083200"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0002819"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0502738102"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2008.09.013"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(02)00086-7"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.22.22.7842-7852.2002"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.20.23.8969-8982.2000"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1068712"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M800517200"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01036"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M207509200"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.168.10.5024"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20060353"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1130512"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.24.17179"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature02330"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature02381"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2008.104"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13619-024-00190-1"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2009.09.014"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-020-00593-7"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2013.06.035"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1008097"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11895"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2293"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2017.90"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11468"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200307056"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.079962"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI68049"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1089\/scd.2012.0306"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA119.009409"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2021.12.008"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-05-159848"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1709"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.880668"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2009.03.008"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1612"},{"key":"e_1_2_11_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80373-6"},{"key":"e_1_2_11_75_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-01-477505"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-09-3071"},{"key":"e_1_2_11_77_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-09-241638"},{"key":"e_1_2_11_78_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200939817"},{"key":"e_1_2_11_79_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20021101"},{"key":"e_1_2_11_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2023.112378"},{"key":"e_1_2_11_81_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2018100249"},{"key":"e_1_2_11_82_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20161263"},{"key":"e_1_2_11_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2242"},{"key":"e_1_2_11_84_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1725"},{"key":"e_1_2_11_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2006.08.015"},{"key":"e_1_2_11_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2021.07.009"},{"key":"e_1_2_11_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.107982"},{"key":"e_1_2_11_88_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-07-590570"},{"key":"e_1_2_11_89_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.2107"},{"key":"e_1_2_11_90_1","doi-asserted-by":"publisher","DOI":"10.1111\/cas.14207"},{"key":"e_1_2_11_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2017.11.009"},{"key":"e_1_2_11_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2021.01.008"},{"key":"e_1_2_11_93_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-04-016907"},{"key":"e_1_2_11_94_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1305656110"},{"key":"e_1_2_11_95_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.3729"},{"key":"e_1_2_11_96_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-06-654111"},{"key":"e_1_2_11_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2013.05.002"},{"key":"e_1_2_11_98_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-05334-4"},{"key":"e_1_2_11_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xgen.2024.100537"},{"key":"e_1_2_11_100_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.72786"},{"key":"e_1_2_11_101_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminoncol.2018.07.005"},{"key":"e_1_2_11_102_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature03147"},{"key":"e_1_2_11_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2013.12.027"},{"key":"e_1_2_11_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(15)00169-2"},{"key":"e_1_2_11_105_1","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2016.175"},{"key":"e_1_2_11_106_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-06-856203"},{"key":"e_1_2_11_107_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers11101427"},{"key":"e_1_2_11_108_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-18-2036"},{"key":"e_1_2_11_109_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2020008101"},{"key":"e_1_2_11_110_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2020005627"},{"key":"e_1_2_11_111_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-018-0211-0"},{"key":"e_1_2_11_112_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-04-709519"},{"key":"e_1_2_11_113_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2018881029"},{"key":"e_1_2_11_114_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-01-621623"},{"key":"e_1_2_11_115_1","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2016.9"},{"key":"e_1_2_11_116_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3160"},{"key":"e_1_2_11_117_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4062"},{"key":"e_1_2_11_118_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200112876"},{"key":"e_1_2_11_119_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1203825"},{"key":"e_1_2_11_120_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00156.2003"},{"key":"e_1_2_11_121_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M600272200"},{"key":"e_1_2_11_122_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.134023"},{"key":"e_1_2_11_123_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms6190"},{"key":"e_1_2_11_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.09.045"},{"key":"e_1_2_11_125_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-11-750976"},{"key":"e_1_2_11_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2009.04.024"},{"key":"e_1_2_11_127_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-05-222976"},{"key":"e_1_2_11_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.07.032"},{"key":"e_1_2_11_129_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-023-06168-2"},{"key":"e_1_2_11_130_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-10-813576"},{"key":"e_1_2_11_131_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI135937"},{"key":"e_1_2_11_132_1","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2014.351"},{"key":"e_1_2_11_133_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-024-02284-w"},{"key":"e_1_2_11_134_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.10702"},{"key":"e_1_2_11_135_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-020-03133-w"},{"key":"e_1_2_11_136_1","doi-asserted-by":"publisher","DOI":"10.1002\/2211-5463.13547"},{"key":"e_1_2_11_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2021.101187"},{"key":"e_1_2_11_138_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-019-0196-7"},{"key":"e_1_2_11_139_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj20030022"},{"key":"e_1_2_11_140_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2007.08.006"},{"key":"e_1_2_11_141_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2015-1852"},{"key":"e_1_2_11_142_1","doi-asserted-by":"publisher","DOI":"10.1530\/JME-18-0178"},{"key":"e_1_2_11_143_1","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.13065"},{"key":"e_1_2_11_144_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.12891"},{"key":"e_1_2_11_145_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1286838"},{"key":"e_1_2_11_146_1","doi-asserted-by":"publisher","DOI":"10.1677\/JOE-06-0191"},{"key":"e_1_2_11_147_1","unstructured":"TalchaiCandAcciliD(2020)Methods for producing enteroendocrine cells that make and secrete insulin."},{"key":"e_1_2_11_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2022.101624"},{"key":"e_1_2_11_149_1","unstructured":"BelvedereS LinHV DeVitaRJ TurcotteSandJohnstoneS(2023)Agents for the treatment of diseases by inhibition of foxo1."},{"key":"e_1_2_11_150_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2019.243543"},{"key":"e_1_2_11_151_1","article-title":"FOXO1 promotes resistance of non\u2010Hodgkin lymphomas to anti\u2010CD20\u2010based therapy","volume":"7","author":"Pyrzynska B","year":"2018","journal-title":"Onco Targets Ther"},{"key":"e_1_2_11_152_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-15-2123"},{"key":"e_1_2_11_153_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-019-0221-9"},{"key":"e_1_2_11_154_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.03.001"},{"key":"e_1_2_11_155_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-07242-1"},{"key":"e_1_2_11_156_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-07300-8"},{"key":"e_1_2_11_157_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2020.274258"},{"key":"e_1_2_11_158_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.09.027"}],"container-title":["FEBS Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/1873-3468.15057","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T04:57:20Z","timestamp":1764392240000},"score":1,"resource":{"primary":{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/10.1002\/1873-3468.15057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,12]]},"references-count":157,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/1873-3468.15057"],"URL":"https:\/\/doi.org\/10.1002\/1873-3468.15057","archive":["Portico"],"relation":{},"ISSN":["0014-5793","1873-3468"],"issn-type":[{"value":"0014-5793","type":"print"},{"value":"1873-3468","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,12]]},"assertion":[{"value":"2024-07-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}