{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T16:35:20Z","timestamp":1793032520197,"version":"4.5.0"},"reference-count":14,"publisher":"Wiley","issue":"20","license":[{"start":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:00:00Z","timestamp":1791849600000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["febs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["FEBS Letters"],"published-print":{"date-parts":[[2026,10]]},"abstract":"\n Progeria is an extremely rare genetic disease in which affected individuals age rapidly due to a specific mutation in the\n LMNA<\/jats:italic>\n gene, which results in the production of progerin, an abnormal protein that damages cell nuclei and causes progressive multi\u2010organ disease. AIProSaB is an Italian association founded by Sammy Basso, who was diagnosed with progeria at the age of two, and by his parents. The association supports research, promotes experimental therapies, and provides information for families and clinicians, with a strong emphasis on understanding LMNA\/progerin biology and developing targeted treatments and gene\u2010editing approaches. As part of our series on patient advocacy,\n FEBS Letters<\/jats:italic>\n interviews Dr. Giovanna Lattanzi, a researcher at the CNR Institute of Molecular Genetics \u2018Luigi Luca Cavalli\u2010Sforza\u2019 in Bologna on the aims, achievements, and activities of AIProSaB.\n <\/jats:p>","DOI":"10.1002\/1873-3468.70481","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:27:33Z","timestamp":1791894453000},"page":"2975-2980","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Collaborating with\n AIProSaB<\/scp>\n \u2014A researcher's perspective on patient advocacy for progeria"],"prefix":"10.1002","volume":"600","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7103-8722","authenticated-orcid":false,"given":"Giovanna","family":"Lattanzi","sequence":"first","affiliation":[{"name":"Istituto di Genetica Molecolare \u201cLuigi Luca Cavalli\u2010Sforza\u201d \u2013 Sede di Bologna c\/o Istituto Ortopedico Rizzoli Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5312-5278","authenticated-orcid":false,"given":"Lavinia","family":"Arseni","sequence":"additional","affiliation":[{"name":"FEBS Letters Editorial Office Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,13]]},"reference":[{"key":"e_1_2_18_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.31346"},{"key":"e_1_2_18_3_1","first-page":"188","article-title":"Progeria: a form of senilism","volume":"73","author":"Gilford H","year":"1904","journal-title":"Practitioner"},{"key":"e_1_2_18_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/095952878606900127"},{"key":"e_1_2_18_5_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1084125"},{"key":"e_1_2_18_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01629"},{"key":"e_1_2_18_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018\u2010005\u20105318\u20106"},{"key":"e_1_2_18_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2020.101073"},{"key":"e_1_2_18_9_1","doi-asserted-by":"publisher","DOI":"10.1042\/BST20110657"},{"key":"e_1_2_18_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.12.028"},{"key":"e_1_2_18_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/19491034.2025.2611484"},{"key":"e_1_2_18_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000001297"},{"key":"e_1_2_18_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25179324"},{"key":"e_1_2_18_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/acel.13285"},{"key":"e_1_2_18_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-018-0338-6"}],"container-title":["FEBS Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/1873-3468.70481","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/1873-3468.70481","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/1873-3468.70481","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T15:43:03Z","timestamp":1793029383000},"score":1,"resource":{"primary":{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/10.1002\/1873-3468.70481"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":14,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1002\/1873-3468.70481"],"URL":"https:\/\/doi.org\/10.1002\/1873-3468.70481","archive":["Portico"],"relation":{},"ISSN":["0014-5793","1873-3468"],"issn-type":[{"value":"0014-5793","type":"print"},{"value":"1873-3468","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"2026-09-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}