{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:58:59Z","timestamp":1791219539102,"version":"4.1.0"},"edition-number":"1","reference-count":71,"publisher":"Wiley","isbn-type":[{"value":"9780470663837","type":"print"},{"value":"9780470720554","type":"electronic"}],"license":[{"start":{"date-parts":[[1980,1,1]],"date-time":"1980-01-01T00:00:00Z","timestamp":315532800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1980,1]]},"DOI":"10.1002\/9780470720554.ch9","type":"other","created":{"date-parts":[[2008,5,30]],"date-time":"2008-05-30T13:23:17Z","timestamp":1212153797000},"page":"135-161","source":"Crossref","is-referenced-by-count":3,"title":["New Aspects of Glutathione Metabolism and Translocation in Mammals"],"prefix":"10.1002","author":[{"given":"Alton","family":"Meister","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Owen W.","family":"Griffith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraham","family":"Novogrodsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suresh S.","family":"Tate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,5,30]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/S0021-9258(19)52816-2","article-title":"Enzymatic oxidation of glutathione","volume":"159","author":"Ames SR","year":"1945","journal-title":"J Biol Chem"},{"key":"e_1_2_1_3_1","first-page":"1803","article-title":"Glutathione metabolism in tumors","volume":"38","author":"Anderson ME","year":"1979","journal-title":"Fed Proc"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(78)80105-7"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/177377a0"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.73.2.420"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(77)90472-6"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(79)80159-3"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.8.3330"},{"key":"e_1_2_1_10_1","first-page":"99","article-title":"Metabolism and transport of glutathione and \u03b3\u2010glutamyl amino acids; in vivo studies with selective inhibitors of the \u03b3\u2010glutamyl cycle enzymes","volume":"38","author":"Griffith OW","year":"1979","journal-title":"Fed Proc"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.76.1.268"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.75.11.5405"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.76.5.2249"},{"key":"e_1_2_1_14_1","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/S0021-9258(17)34188-1","article-title":"Inhibition of glutathione biosynthesis by prothionine sulphoximine (S\u2010n\u2010propyl homocysteine sulphoximine), a selective inhibitor of y\u2010glutamylcysteine synthetase","volume":"254","author":"Griffith OW","year":"1979","journal-title":"J Biol Chem"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4165(78)90037-5"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj0510025"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(78)90430-7"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(69)90512-6"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365517009046241"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-67132-6_24"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(75)90494-4"},{"key":"e_1_2_1_22_1","first-page":"305","article-title":"Effects of amino acids on the function of the isolated perfused rat kidney","volume":"33","author":"Maack T","year":"1974","journal-title":"Fed Proc"},{"key":"e_1_2_1_23_1","first-page":"671","volume-title":"The enzymes","author":"Meister A","year":"1974"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-81-2-247"},{"key":"e_1_2_1_25_1","first-page":"101","volume-title":"Metabolic pathways","author":"Meister A","year":"1975"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-67132-6_7"},{"key":"e_1_2_1_27_1","first-page":"328","volume-title":"The metabolic basis of inherited diseases","author":"Meister A","year":"1978"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.45.070176.003015"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4684-2658-8_13"},{"key":"e_1_2_1_30_1","series-title":"Ciba Found Symp 50","first-page":"141","volume-title":"Peptide transport and hydrolysis","author":"Meister A","year":"1977"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(78)90416-3"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.73.7.2414"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.71.3.921"},{"key":"e_1_2_1_34_1","doi-asserted-by":"crossref","first-page":"5184","DOI":"10.1016\/S0021-9258(18)50577-9","article-title":"Glutathione synthetase; purification from rat kidney and mapping of the substrate binding sites","volume":"254","author":"Oppenheimer L","year":"1979","journal-title":"J Biol Chem"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(75)90448-9"},{"key":"e_1_2_1_36_1","unstructured":"RichmanPG 1969y\u2010Glutamylcysteine synthetase and related studies on the metabolism of the y\u2010glutamyl group. Doctoral Dissertation Cornell University Graduate School of Medical Sciences New York."},{"key":"e_1_2_1_37_1","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1016\/S0021-9258(19)41830-9","article-title":"Regulation of \u03b3\u2010glutamyl\u2010cysteine synthetase by non\u2010allosteric feedback inhibition by glutathione","volume":"250","author":"Richman P","year":"1975","journal-title":"J Biol Chem"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(75)80062-3"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.71.8.2969"},{"key":"e_1_2_1_40_1","doi-asserted-by":"crossref","first-page":"2599","DOI":"10.1016\/S0021-9258(17)40500-X","article-title":"\u03b3\u2010Glutamylcysteine synthetase: further purification, \u201chalf of the sites\u201d reactivity, subunits, and specificity","volume":"252","author":"Sekura R","year":"1977","journal-title":"J Biol Chem"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(76)90242-4"},{"key":"e_1_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4832-2900-3.50014-6"},{"key":"e_1_2_1_43_1","first-page":"1799","article-title":"\u03b3\u2010Glutamyl cyclotransferase from rat kidney; sulfhydryl groups and isolation of a stable form of the enzyme","volume":"253","author":"Taniguchi N","year":"1978","journal-title":"J Biol Chem"},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-472702-1.50051-7"},{"key":"e_1_2_1_45_1","doi-asserted-by":"crossref","first-page":"7593","DOI":"10.1016\/S0021-9258(19)81279-6","article-title":"Interaction of \u03b3\u2010glutamyl transpeptidase with amino acids. dipeptides, and derivatives and analogs of glutathione","volume":"249","author":"Tate SS","year":"1974","journal-title":"J Biol Chem"},{"key":"e_1_2_1_46_1","doi-asserted-by":"crossref","first-page":"4619","DOI":"10.1016\/S0021-9258(19)41346-X","article-title":"Identity of maleate\u2010stimulated \u2018glutaminase\u2019 with y\u2010glutamyl transpeptidase in rat kidney","volume":"250","author":"Tate SS","year":"1975","journal-title":"J Biol Chem"},{"key":"e_1_2_1_47_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.73.8.2599"},{"key":"e_1_2_1_48_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.3.931"},{"key":"e_1_2_1_49_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.75.10.4806"},{"key":"e_1_2_1_50_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.76.6.2715"},{"key":"e_1_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)39919-2"},{"key":"e_1_2_1_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(69)90064-5"},{"key":"e_1_2_1_53_1","unstructured":"Van Der WerfP 1970Metabolism of 5\u2010oxo\u2010L\u2010proline; conversion to L\u2010glutamate in an ATP\u2010dependent reaction catalyzed by 5\u2010oxoprolinase. Doctoral Dissertation Cornell University Graduate School of Medical Sciences New York."},{"key":"e_1_2_1_54_1","first-page":"519","article-title":"The metabolic formation and utilization of 5\u2010oxo\u2010L\u2010proline (l\u2010pyroglutamate, L\u2010pyrrolidone carboxylate)","volume":"43","author":"Van Der Werf P","year":"1975","journal-title":"Adv Enzymol Relat Areas Mol Biol"},{"key":"e_1_2_1_55_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.68.12.2982"},{"key":"e_1_2_1_56_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.70.3.759"},{"key":"e_1_2_1_57_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.71.4.1026"},{"key":"e_1_2_1_58_1","doi-asserted-by":"crossref","first-page":"6686","DOI":"10.1016\/S0021-9258(19)40988-5","article-title":"5\u2010oxo\u2010L\u2010prolinase (L\u2010pyroglutamate hydrolase); purification and catalytic properties","volume":"250","author":"Van Der Werf P","year":"1975","journal-title":"J Biol Chem"},{"key":"e_1_2_1_59_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.71.6.2505"},{"key":"e_1_2_1_60_1","first-page":"2629","article-title":"Structure\u2010function relationships of 5\u2010oxo\u2010L\u2010prolinase","volume":"38","author":"Williamson J","year":"1979","journal-title":"Fed Proc"},{"key":"e_1_2_1_61_1","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/S0021-9258(18)51286-2","article-title":"The effect of pH on the formation of pyrrolidone\u2010carboxylic acid and glutamic acid during enzymatic hydrolysis of glutathione by rat kidney extract","volume":"145","author":"Woodward GE","year":"1942","journal-title":"J Biol Chem"},{"key":"e_1_2_1_62_1","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0021-9258(17)35148-7","article-title":"Enzymatic oxidation and hydrolysis of glutathione by different tissues","volume":"161","author":"Ziegenhagen AJ","year":"1947","journal-title":"J Biol Chem"},{"key":"e_1_2_1_63_1","unstructured":"References"},{"key":"e_1_2_1_64_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365517009046241"},{"key":"e_1_2_1_65_1","doi-asserted-by":"crossref","first-page":"2787","DOI":"10.1016\/S0021-9258(17)30142-4","article-title":"Metabolism of glutathione and a glutathione conjugate by isolated kidney cells","volume":"254","author":"Jones DP","year":"1979","journal-title":"J Biol Chem"},{"key":"e_1_2_1_66_1","first-page":"328","volume-title":"The metabolic basis of inherited diseases","author":"Meister A","year":"1978"},{"key":"e_1_2_1_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(75)80062-3"},{"key":"e_1_2_1_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(72)80434-4"},{"key":"e_1_2_1_69_1","first-page":"261","volume-title":"Glutathione","author":"Sies H","year":"1973"},{"key":"e_1_2_1_70_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.75.10.4806"},{"key":"e_1_2_1_71_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.76.6.2715"},{"key":"e_1_2_1_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(75)90132-1"}],"container-title":["Novartis Foundation Symposia","Ciba Foundation Symposium 72 \u2010 Sulphur in Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2F9780470720554.ch9","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/9780470720554.ch9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,26]],"date-time":"2023-08-26T10:54:33Z","timestamp":1693047273000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/9780470720554.ch9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,1]]},"ISBN":["9780470663837","9780470720554"],"references-count":71,"alternative-id":["10.1002\/9780470720554.ch9","10.1002\/SERIES1767","10.1002\/9780470720554"],"URL":"https:\/\/doi.org\/10.1002\/9780470720554.ch9","archive":["Portico"],"relation":{},"ISSN":["1935-4657"],"issn-type":[{"value":"1935-4657","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,1]]}}}