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To assist in outlining basic approaches to evaluating mice clinically as well as microscopically with the help of a pathologist, methods are provided here that are used routinely in many laboratories. The mouse is a very useful mammalian model system for studying normal and abnormal (disease) development, and there is a high degree of correlation not only with human biology and medicine but with that of most other mammalian species. Utilizing basic approaches standardizes analysis and provides quality samples for analysis. <jats:italic>Curr. Protoc. Mouse Biol<\/jats:italic>. 4:105\u2010119 \u00a9 2014 by John Wiley &amp; Sons, Inc.<\/jats:p>","DOI":"10.1002\/9780470942390.mo140035","type":"journal-article","created":{"date-parts":[[2014,9,3]],"date-time":"2014-09-03T14:44:46Z","timestamp":1409755486000},"page":"105-119","source":"Crossref","is-referenced-by-count":1,"title":["Systematic Evaluation of Skin and Adnexa in Mutant Laboratory Mice"],"prefix":"10.1002","volume":"4","author":[{"given":"Kathleen A.","family":"Silva","sequence":"first","affiliation":[{"name":"The Jackson Laboratory  Bar Harbor Maine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria E.","family":"Kennedy","sequence":"additional","affiliation":[{"name":"The Jackson Laboratory  Bar Harbor Maine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Sundberg","sequence":"additional","affiliation":[{"name":"The Jackson Laboratory  Bar Harbor Maine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,9,3]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"121","volume-title":"Systematic Characterization of Mouse Mutations","author":"Bechtold L.S.","year":"2000"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1009534129331"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0625.2002.00112.x"},{"key":"e_1_2_10_5_1","first-page":"557","article-title":"Comparative morphological study of the mammary gland in a high and a low tumor strain of mice","volume":"14","author":"Fekete E.","year":"1938","journal-title":"Am. 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