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Flexible electronics also call for customized chips in smart wearable devices. Common chips in intelligent systems process digital signals, and continuous operation of the system clock brings great power consumption. Herein, an intelligent gesture recognition system is developed by combining the flexible 2D materials and an analog computing chip. The pressure\u2010sensitive sponge with graphene fillings is proposed as a piezoresistive sensor. A nine\u2010sensor array is used to detect the pressure field distribution caused by hand movement. To get rid of the power consumption caused by the system clock, a novel analog\u2010computing customized chip which adopts a near\u2010sensor processing architecture is proposed. It implements the binary neural network algorithm with an analog circuit and completes the recognition of the transmission signal at the hardware level. The chip possesses a low power consumption which is less than 1.8\u2009mW. Moreover, a glove assembled by highly pressure\u2010sensitive material recognizes mute gestures including Arabic numerals 0\u20139, with a recognition rate as high as 98.5%. 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