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Herein, a skin\u2010like and stretchable optical fiber (SSOF) sensor with excellent stretchability (up to 100%), flexibility, and excellent compliance with skin is reported. A hybrid coding based on the light intensity difference of two fiber Bragg gratings (FBGs) is created to achieve the resistance for light power fluctuations and the capability of distributed measurement. The SSOF sensor has outstanding durability (&gt;10\u2009000 cycles), waterproofness, and impact resistance. And it can stably work in heat (55\u2009\u00b0C) or cold (\u22480\u2009\u00b0C) environment as well. Furthermore, the SSOF sensor\u2010based human\u2013computer interaction system is created to achieve the distributed monitoring of physiological parameters and human full\u2010body movement leading to the enormous potential for virtual reality (VR) and rehabilitation therapy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/aisy.202100193","type":"journal-article","created":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T08:45:46Z","timestamp":1638434746000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["A Skin\u2010Like and Highly Stretchable Optical Fiber Sensor with the Hybrid Coding of Wavelength\u2013Light Intensity"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7323-169X","authenticated-orcid":false,"given":"Tianliang","family":"Li","sequence":"first","affiliation":[{"name":"School of Mechanical and Electronic Engineering Wuhan University of Technology  Wuhan 430070 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifei","family":"Su","sequence":"additional","affiliation":[{"name":"School of Mechanical and Electronic Engineering Wuhan University of Technology  Wuhan 430070 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fayin","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Mechanical and Electronic Engineering Wuhan University of Technology  Wuhan 430070 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinqin","family":"Liao","sequence":"additional","affiliation":[{"name":"School of Electronic Science and Engineering Xiamen University  422 Siming South Road Xiamen 361005 China"},{"name":"School of Electrical and Electronic Engineering Nanyang Technological University  50 Nanyang Avenue Singapore 639798 Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, West China Hospital Sichuan University  No. 37 Guo Xue Alley, Wuhou District Chengdu Sichuan 610041 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, West China Hospital Sichuan University  No. 37 Guo Xue Alley, Wuhou District Chengdu Sichuan 610041 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuegang","family":"Tan","sequence":"additional","affiliation":[{"name":"School of Mechanical and Electronic Engineering Wuhan University of Technology  Wuhan 430070 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zude","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Mechanical and Electronic Engineering Wuhan University of Technology  Wuhan 430070 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.8b00500"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nanoen.2019.05.033"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201504755"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)32656-8"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/s19030686"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0NR03446K"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-16040-y"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7TC01169E"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nanoen.2018.08.036"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-40828-8"},{"key":"e_1_2_8_12_1","volume":"11","author":"Dong C.","year":"2020","journal-title":"Nat. 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