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The synergistic interplay of additive manufacturing (AM) technologies, specifically 4D\u2010printing, and artificial intelligence (AI), have widened the design space and accelerated the design phase. 4D\u2010printing, intended as the combination of 3D\u2010printing with a fourth dimension (i.e., time), ensures the fabrication of complex topologies with materials that can be selectively triggered to change specific features (e.g., shape, color), whereas the use of smart inks or embedded sensors can bring additional functionalities (e.g., repairing, sensing, actuating) to fulfill the requirements of the targeted application. AI is the tool allowing scientists to train machines for developing human\u2010like capabilities to discern, predict, and represent the statistically significant behavior of a phenomenon. If applied to the design of smart structures, it can be a powerful and efficient tool capable of reducing the time\u2010to\u2010manufacturing, improving the traditional design approach. 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