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Despite their success in the field, their precision synthesis and fundamental mechanistic studies remain a challenge. The vast colloidal synthesis and processing parameters of LHP NCs in combination with the batch\u2010to\u2010batch and lab\u2010to\u2010lab variation problems further complicate their progress. In response, a self\u2010driving fluidic micro\u2010processor is presented for accelerated navigation through the complex synthesis and processing parameter space of NCs with multistage chemistries. The capability of the developed autonomous experimentation strategy is demonstrated for a time\u2010, material\u2010, and labor\u2010efficient search through the sequential halide exchange and cation doping reactions of LHP NCs. Next, a machine learning model of the modular fluidic micro\u2010processors is autonomously built for accelerated fundamental studies of the in\u2010flow metal cation doping of LHP NCs. The surrogate model of the sequential halide exchange and cation doping reactions of LHP NCs is then utilized for five closed\u2010loop synthesis campaigns with different target NC doping levels. The precise and intelligent NC synthesis and processing strategy, presented herein, can be further applied toward the autonomous discovery and development of novel impurity\u2010doped NCs with applications in next\u2010generation energy technologies.<\/jats:p><\/jats:sec>","DOI":"10.1002\/aisy.202200017","type":"journal-article","created":{"date-parts":[[2022,3,13]],"date-time":"2022-03-13T11:24:36Z","timestamp":1647170676000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Autonomous Nanocrystal Doping by Self\u2010Driving Fluidic Micro\u2010Processors"],"prefix":"10.1002","volume":"4","author":[{"given":"Fazel","family":"Bateni","sequence":"first","affiliation":[{"name":"Department of Chemical and Biomolecular Engineering North Carolina State University  Raleigh NC 27695-7905 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert 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