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Herein, a hyperbaric vacuum\u2010based artificial muscle (Hyper\u2010VAM) making use of both positive and negative pressures almost interchangeably is described. This is done by placing a vacuum\u2010based actuator inside a hyperbaric chamber which enables both the large deformations possible using negative pressure, and large forces through the action of high pressure differential, exceeding those possible using only negative pressure. This actuator can lift heavy payloads (up to 80\u2009kg) for its entire contraction range, with large deformations (89.1% contraction of the active length) and high power (maximum power of 101.3\u2009W), while using relatively low pressures, which can be supplied by a portable pneumatic pump. By exchanging air between the two chambers in closed\u2010loop pneumatic actuation, this actuator can also be driven using a single pump without exchanging air with the environment and its position can be controlled using a single pneumatic regulator.<\/jats:p><\/jats:sec>","DOI":"10.1002\/aisy.202200090","type":"journal-article","created":{"date-parts":[[2022,7,24]],"date-time":"2022-07-24T21:36:54Z","timestamp":1658698614000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Hyperbaric Vacuum\u2010Based Artificial Muscles for High\u2010Performance Actuation"],"prefix":"10.1002","volume":"5","author":[{"given":"Altair","family":"Coutinho","sequence":"first","affiliation":[{"name":"School of Mechanical Engineering Sungkyunkwan University  Suwon 16419 Korea"}]},{"given":"Jae Hyeong","family":"Park","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering Sungkyunkwan University  Suwon 16419 Korea"}]},{"given":"Babar","family":"Jamil","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering Sungkyunkwan University  Suwon 16419 Korea"}]},{"given":"Hyouk Ryeol","family":"Choi","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering Sungkyunkwan University  Suwon 16419 Korea"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1358-9630","authenticated-orcid":false,"given":"Hugo","family":"Rodrigue","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering Sungkyunkwan University  Suwon 16419 Korea"}]}],"member":"311","published-online":{"date-parts":[[2022,7,24]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibtech.2013.03.002"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201800907"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1109\/70.481753"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1089\/soro.2017.0044"},{"key":"e_1_2_11_6_1","first-page":"33","volume":"13","author":"Geddes L. 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