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Herein, a sensory modality that has been largely neglected is explored: the ability to perceive wetness. Providing moisture\u2010related information to prosthesis users can increase their overall sensory palette toward a more natural sensory experience. A rapid decrease in skin temperature is found to trigger the illusion of contact with something wet. Two body parts were tested, the upper arm and the lateral abdomen, in a group of non amputated participants, and it was found that a wetness sensation can be elicited and maintained for at least 10 s in 86% and 93% of participants, respectively. It is then demonstrated how to mediate the wetness sensation in real\u2010time using a thermal wearable device that mimics the thermal properties of the skin. Finally, two upper limb amputee individuals used their prosthetic arm, sensorized with the device, to discriminate between three levels of moisture; their detection accuracy was similar to one they had with their intact hands. The current study is a stepping stone for future prostheses aimed at restoring the richness of sensory experience in upper limb amputees.<\/jats:p>","DOI":"10.1002\/aisy.202300512","type":"journal-article","created":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T02:30:30Z","timestamp":1705631430000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Remapping Wetness Perception in Upper Limb Amputees"],"prefix":"10.1002","volume":"6","author":[{"given":"Maria","family":"Ploumitsakou","sequence":"first","affiliation":[{"name":"Bertarelli Foundation Chair in Translational Neural Engineering Neuro\u2010X Institute \u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne  Lausanne 1015 Switzerland"},{"name":"Laboratory for Behavioral Neurology and Imaging of Cognition Department of Fundamental Neuroscience University of Geneva  Geneva 1202 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