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While most docking programs usually manage to produce at least a near\u2010native pose for a bioactive molecule inside its binding pocket, their integrated classical scoring functions (SFs) generally fail to prioritize this pose. Many studies have been carried out to tackle this SF problem, offering multiple pose refinement and\/or classification methods, albeit with limitations. This study presents a new support vector machine model for pose classification, called \u201cClassyPose\u201d, which predicts the probability that a receptor\u2010bound ligand conformation could be near\u2010native, without any additional pose optimization step. 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