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Using a specific Schwann cell marker, the 1E8 antibody, we have found that olfactory nerve glia can be identified throughout development. These glia appear to originate in the olfactory placode and migrate initially into the periphery of the olfactory nerve, and later into the center of the nerve. Olfactory nerve glia enter the presumptive olfactory bulb with the olfactory receptor neuron axons and distribute themselves along the edge of the olfactory nerve layer. The fact that olfactory nerve glia are specifically immunostained by the 1E8 monoclonal antibody, which recognizes the Schwann cell\u2010specific protein P<jats:sub>0<\/jats:sub>, suggests that these cells more closely resemble Schwann cells than astrocytes or enteric glia. These results support and extend previous findings suggesting that olfactory nerve glia have distinctive developmental and anatomical features which may be important to the regenerative capacity of the olfactory system. \u00a9 1992 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/aja.1001940308","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T21:00:19Z","timestamp":1109451619000},"page":"231-238","source":"Crossref","is-referenced-by-count":48,"title":["Development of olfactory nerve glia defined by a monoclonal antibody specific for schwann cells"],"prefix":"10.1002","volume":"194","author":[{"suffix":"Jr.","given":"Robert B.","family":"Norgren","sequence":"first","affiliation":[]},{"given":"Nancy","family":"Ratner","sequence":"additional","affiliation":[]},{"given":"Robert","family":"Brackenbury","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2005,2,3]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"12","article-title":"Neurogenesis and regeneration in the primary olfactory pathway of mammals","volume":"23","author":"Barber P. 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