{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:06:05Z","timestamp":1761523565801},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[1985,5,1]],"date-time":"1985-05-01T00:00:00Z","timestamp":483753600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1985,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A review of 90 patients presenting in Leeds over the period 1976-80 with synchronous hepatic metastases from colorectal cancer has been undertaken. The median survival for the group was 10.3 months (range 1\u201348 months). A multivariate analysis identified factors in the history and examination of the patient, results of biochemical and haematological investigations and characteristics of both the primary and secondary tumour, which influenced survival. Recognition of these factors allowed both a clinical scoring index and computer survival model to be constructed. When applied to the group as a whole both were reasonably accurate at predicting survival (62 per cent for the survival model and 66 per cent for the scoring index). However, the computer model correctly identified 80 per cent of the long-term survivors (&amp;gt; 12 months from the time of diagnosis). It is concluded that many trials of therapy for hepatic metastases from colorectal cancer have failed to consider the natural history of the disease and the identification of prognostic indices should allow for adequate stratification within the treatment arms of any future study.<\/jats:p>","DOI":"10.1002\/bjs.1800720514","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T04:40:51Z","timestamp":1172896851000},"page":"373-377","source":"Crossref","is-referenced-by-count":70,"title":["Factors affecting survival in patients presenting with synchronous hepatic metastases from colorectal cancer: A clinical and computer analysis"],"prefix":"10.1093","volume":"72","author":[{"given":"P J","family":"Finan","sequence":"first","affiliation":[{"name":"University Department of Surgery, St James's University Hospital and Unit for Cancer Research, University of Leeds , Leeds,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R J","family":"Marshall","sequence":"additional","affiliation":[{"name":"University Department of Surgery, St James's University Hospital and Unit for Cancer Research, University of Leeds , Leeds,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E H","family":"Cooper","sequence":"additional","affiliation":[{"name":"University Department of Surgery, St James's University Hospital and Unit for Cancer Research, University of Leeds , Leeds,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G R","family":"Giles","sequence":"additional","affiliation":[{"name":"University Department of Surgery, St James's University Hospital and Unit for Cancer Research, University of Leeds , Leeds,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1985,5,1]]},"reference":[{"key":"2024092717123469800_bib1","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1002\/1097-0142(196901)23:1<198::AID-CNCR2820230126>3.0.CO;2-J","article-title":"The natural history of primary and secondary malignant tumours of the liver. 1. 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Prognostic factors in 200 melanoma patients with distant metastases (stage III)","volume":"1","author":"Balch","year":"1983","journal-title":"J Clin Oncol"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.1800720514","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/72\/5\/373\/59379416\/bjs1800720514.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/72\/5\/373\/59379416\/bjs1800720514.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T17:12:58Z","timestamp":1727457178000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/72\/5\/373\/6193211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,5,1]]},"references-count":17,"journal-issue":{"issue":"5","published-online":{"date-parts":[[1985,5,1]]},"published-print":{"date-parts":[[1985,5,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.1800720514","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"type":"print","value":"0007-1323"},{"type":"electronic","value":"1365-2168"}],"subject":[],"published-other":{"date-parts":[[1985,5]]},"published":{"date-parts":[[1985,5,1]]}}}